Most cited papers from Pharmalog (Germany)

Pharmalog (Germany)

What are the most cited papers from Pharmalog (Germany)?

The most cited paper from Pharmalog (Germany) is "The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial" (M. M. Heiss, P. Murawa, P. Koralewski et al., 2010), with 557 citations. Next come "Defective smooth muscle regulation in cGMP kinase I‐deficient mice" (502) and "Molecular Basis for CA2+ Channel Diversity" (461).

Published TypeFieldAccessCitations

Showing 50 of 61 papers. Every paper with more than 37 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial M. M. Heiss, P. Murawa, P. Koralewski et al. · International Journal of Cancer Open access	28 Apr 2010	557
2	Defective smooth muscle regulation in cGMP kinase I‐deficient mice Alexander Pfeifer, Peter Klatt, Steffen Massberg et al. · The EMBO Journal Open access	Jun 1998	502
3	Molecular Basis for CA2+ Channel Diversity Franz Bruno Hofmann, Martin Biel, Veit Flockerzi · Annual Review of Neuroscience Open access	Mar 1994	461
4	Development and approval of the trifunctional antibody catumaxomab (anti-EpCAM×anti-CD3) as a targeted cancer immunotherapy Diane Seimetz, Horst Lindhofer, Carsten Bokemeyer · Cancer Treatment Reviews	30 Mar 2010	285
5	Effective Relief of Malignant Ascites in Patients with Advanced Ovarian Cancer by a Trifunctional Anti-EpCAM × Anti-CD3 Antibody: A Phase I/II Study Alexander Burges, Pauline Wimberger, Carolin Kümper et al. · Clinical Cancer Research	Jul 2007	258
6	Determination of reference intervals for serum creatinine, creatinine excretion and creatinine clearance with an enzymatic and a modified Jaffé method Wolfgang Junge, Baerbel Wilke, Atef Halabi et al. · Clinica Chimica Acta	29 Apr 2004	244
7	Recovery of platelet function after discontinuation of clopidogrel treatment in healthy volunteers Artur‐Aron Weber, Marina Braun, Thomas Hohlfeld et al. · British Journal of Clinical Pharmacology Open access	Sep 2001	178
8	Intra-articular sodium hyaluronate in osteoarthritis of the knee: a multicenter, double-blind study W. Puhl, A Bernau, H. Greiling et al. · Osteoarthritis and Cartilage	Oct 1993	144
9	Structural and functional characterization of the trifunctional antibody catumaxomab Dirk Chelius, Peter Ruf, Patrick R. Gruber et al. · mAbs Open access	May 2010	144
10	Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-α and Modulated by IL23R Genotype Status Johannes Stallhofer, Matthias Friedrich, Astrid Konrad-Zerna et al. · Inflammatory Bowel Diseases Open access	Aug 2015	130
11	Treatment of pruritus with topically applied opiate receptor antagonist Paul Lorenz Bigliardi, Holger Stammer, Gerhard Jost et al. · Journal of the American Academy of Dermatology	23 Feb 2007	127
12	Immunotherapy of malignant ascites with trifunctional antibodies M. M. Heiss, Michael Alfred Ströhlein, Michael Jäger et al. · International Journal of Cancer Open access	19 May 2005	119
13	Long-Term Potentiation in the Hippocampal CA1 Region of Mice Lacking cGMP-Dependent Kinases Is Normal and Susceptible to Inhibition of Nitric Oxide Synthase Thomas Kleppisch, Alexander Pfeifer, Peter Klatt et al. · Journal of Neuroscience Open access	1999	117
14	Reactions of nitrosobenzene with reduced glutathione Peter Eyer · Chemico-Biological Interactions	Feb 1979	109
15	Urinary Excretion and Metabolism of Arbutin after Oral Administration of Arctostaphylos uvae ursi Extract as Film‐Coated Tablets and Aqueous Solution in Healthy Humans G Schindler, Ulrich Patzak, Benno Brinkhaus et al. · The Journal of Clinical Pharmacology	Aug 2002	103
16	Characterisation of the new EpCAM-specific antibody HO-3: implications for trifunctional antibody immunotherapy of cancer Peter Ruf, Olivier Gires, Michael Jäger et al. · British Journal of Cancer Open access	10 Jul 2007	102
17	Treatment of non-small cell lung cancer patients with the trifunctional monoclonal antibody catumaxomab (anti-EpCAM × anti-CD3): a phase I study Martin Sebastian, Bernward Passlick, Hilke Friccius-Quecke et al. · Cancer Immunology Immunotherapy Open access	4 Apr 2007	100
18	EpCAM an immunotherapeutic target for gastrointestinal malignancy: current experience and future challenges M. Asif Chaudry, K. M. Sales, Peter Ruf et al. · British Journal of Cancer Open access	27 Feb 2007	96
19	The Trifunctional Antibody Ertumaxomab Destroys Tumor Cells That Express Low Levels of Human Epidermal Growth Factor Receptor 2 Michael Jäger, Alexandra Schoberth, Peter Ruf et al. · Cancer Research Open access	13 May 2009	94
20	Efficacy and Tolerability of a Fluid Extract Combination of Thyme Herb and Ivy Leaves and Matched Placebo in Adults Suffering from Acute Bronchitis with Productive Cough Bernd Kemmerich, Reinhild Eberhardt, Holger Stammer · Arzneimittelforschung	22 Dec 2011	92
21	Pharmacokinetics, immunogenicity and bioactivity of the therapeutic antibody catumaxomab intraperitoneally administered to cancer patients Peter Ruf, Michael Kluge, Michael Jäger et al. · British Journal of Clinical Pharmacology Open access	Feb 2010	91
22	Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22phox in mice Karine M. Laude, Hua “Linda” Cai, Bruno Fink et al. · American Journal of Physiology-Heart and Circulatory Physiology	8 Oct 2004	90
23	An acylated allose-containing 8-hydroxyflavone glycoside from Veronica filiformis Vedantha Mohan Chari, Rence J. Grayer-Barkmeijer, Jeffrey B. Harborne et al. · Phytochemistry	1981	89
24	p8-deficient fibroblasts grow more rapidly and are more resistant to adriamycin-induced apoptosis Sophie Vasseur, Albrecht Hoffmeister, Andrés C. García‐Montero et al. · Oncogene	7 Mar 2002	88
25	Slack Channels Expressed in Sensory Neurons Control Neuropathic Pain in Mice Ruirui Lu, Anne E. Bausch, Wiebke Kallenborn-Gerhardt et al. · Journal of Neuroscience Open access	21 Jan 2015	88
26	AntimiR-132 Attenuates Myocardial Hypertrophy in an Animal Model of Percutaneous Aortic Constriction Rabea Hinkel et al. · Journal of the American College of Cardiology Open access	Jun 2021	85
27	Droloxifene, a new antiestrogen: Its role in metastatic breast cancer Winrich Rauschning, Kathleen I. Pritchard · Breast Cancer Research and Treatment	1994	82
28	Tissue Binding versus Plasma Binding of Drugs: General Principles and Pharmacokinetic Consequences Burckhard Fichtl, A von Nieciecki, K Walter · Advances in Drug Research Book chapter	1991	81
29	β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells Raphael Silvanus Haider, Edda S. F. Matthees, Julia Drube et al. · Nature Communications Open access	26 Sep 2022	78
30	Pain Perception in Mice Lacking the β3 Subunit of Voltage-activated Calcium Channels Manabu Murakami, Bernd K. Fleischmann, Carmen De Felipe et al. · Journal of Biological Chemistry Open access	Oct 2002	78
31	Treatment of recalcitrant venous leg ulcers with autologous keratinocytes in fibrin sealant: A multinational randomized controlled clinical trial Wolfgang Vanscheidt, A. Ukat, Vratislav Horák et al. · Wound Repair and Regeneration Open access	May 2007	78
32	Humoral response to catumaxomab correlates with clinical outcome: Results of the pivotal phase II/III study in patients with malignant ascites Marion Gabriele Ott, Frederik Marmé, Gerhard Moldenhauer et al. · International Journal of Cancer Open access	23 Jun 2011	76
33	High CA repeat numbers in intron 13 of the endothelial nitric oxide synthase gene and increased risk of coronary artery disease Karl Stangl, Ingolf Cascorbi, Michael Laule et al. · Pharmacogenetics	Mar 2000	69
34	Preclinical data for Droloxifene Max Hasmann, Benno Rattel, R. Löser · Cancer Letters	Sep 1994	68
35	Phase III Randomized Trial of Droloxifene and Tamoxifen As First-Line Endocrine Treatment of ER/PgR-Positive Advanced Breast Cancer Aman U. Buzdar, Daniel F.C. Hayes, A. El-Khoudary et al. · Breast Cancer Research and Treatment	May 2002	67
36	Bi20 (fBTA05), a novel trifunctional bispecific antibody (anti‐CD20 × anti‐CD3), mediates efficient killing of B‐cell lymphoma cells even with very low CD20 expression levels Michael Stanglmaier, M. Faltin, Peter Ruf et al. · International Journal of Cancer	10 Jun 2008	67
37	Signaling through cGMP-Dependent Protein Kinase I in the Amygdala Is Critical for Auditory-Cued Fear Memory and Long-Term Potentiation Cindy Paul, Florian Schöberl, Pascal Weinmeister et al. · Journal of Neuroscience Open access	24 Dec 2008	61
38	Cytotoxic Sesquiterpene Lactones Mediate their Death-Inducing Effect in Leukemia T Cells by Triggering Apoptosis Verena Maria Dirsch, Hermann Stuppner, Angelika M. Vollmar · Planta Medica	17 Aug 2001	59
39	Pivotal role of the interstitial cells of Cajal in the nitric oxide signaling pathway of rat small intestine Hermann Salmhofer, Winfried Neuhuber, Peter Ruth et al. · Cell and Tissue Research	Sep 2001	58
40	Flow cytometry analysis of platelet cyclooxygenase‐2 expression: induction of platelet cyclooxygenase‐2 in patients undergoing coronary artery bypass grafting Artur‐Aron Weber, Boris Przytulski, Marc M. Schumacher et al. · British Journal of Haematology	25 Apr 2002	56
41	Two new trifunctional antibodies for the therapy of human malignant melanoma Peter Ruf, Michael Jäger, Joachim W. Ellwart et al. · International Journal of Cancer	13 Nov 2003	55
42	Inhibition of growth‐factor‐activated proliferation by anti‐estrogens and effects on early gene expression of mcf‐7 cells Katja Wosikowski, Willy Küng, Max Hasmann et al. · International Journal of Cancer	21 Jan 1993	55
43	Proteomic comparison of etioplast and chloroplast protein complexes Matthias Plöscher, Veronika Reisinger, Lutz Andreas Eichacker · Journal of Proteomics	Apr 2011	54
44	BKCa channels expressed in sensory neurons modulate inflammatory pain in mice Ruirui Lu, Robert Łukowski, Matthias Sausbier et al. · Pain	11 Dec 2013	52
45	The sodium-activated potassium channel Slack is required for optimal cognitive flexibility in mice Anne E. Bausch, Rebekka Dieter, Yvette Nann et al. · Learning & Memory Open access	15 Jun 2015	50
46	Immunotherapy of recurrent B-cell malignancies after allo-SCT with Bi20 (FBTA05), a trifunctional anti-CD3 × anti-CD20 antibody and donor lymphocyte infusion Raymund Buhmann, Belinda Pinto Simões, Michael Stanglmaier et al. · Bone Marrow Transplantation	13 Oct 2008	49
47	Impaired motor skill learning and altered seizure susceptibility in mice with loss or gain of function of the Kcnt1 gene encoding Slack (KNa1.1) Na+-activated K+ channels Imran H. Quraishi, Michael R. Mercier, Heather M. McClure et al. · Scientific Reports Open access	21 Feb 2020	48
48	Intracellular localization, vesicular accumulation and kinetics of daunorubicin in sensitive and multidrug-resistant gastric carcinoma EPG85-257 cells André Seidel, Andreas Bunge, Birgit M. Schaefer et al. · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin	Apr 1995	48
49	Influence of process parameters on sustained-release theophylline pellets coated with aqueous polymer dispersions and organic solvent-based polymer solutions Claudio Alexander Lorck, P Grunenberg, H Jünger et al. · European Journal of Pharmaceutics and Biopharmaceutics	Apr 1997	48
50	Lipid-independent control of endothelial and neuronal TRPC3 channels by light Oleksandra Tiapko, Niroj Shrestha, Sonja Lindinger et al. · Chemical Science Open access	2019	45

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.