Institution · Pharmo Institute
Most cited papers from Pharmo Institute
What are the most cited papers from Pharmo Institute?
The most cited paper from Pharmo Institute is "Novel crosslinking methods to design hydrogels" (Wim E. Hennink, Cornelus F. van Nostrum, 2002), with 1,964 citations. Next come "mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability" (1,561) and "A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions" (1,385).
Showing 50 of 60 papers. Every paper with more than 323 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Novel crosslinking methods to design hydrogels Wim E. Hennink, Cornelus F. van Nostrum · Advanced Drug Delivery Reviews | 2002 | 1,964 |
| 2 | mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability Linde Schoenmaker, Dominik Witzigmann, Jayesh A. Kulkarni et al. · International Journal of Pharmaceutics | 8 Apr 2021 | 1,561 |
| 3 | A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions Eugène van Puijenbroek, Andrew M. Bate, Hubert G.M. Leufkens et al. · Pharmacoepidemiology and Drug Safety | 2002 | 1,385 |
| 4 | Colonic bacterial composition in Parkinson's disease Ali Keshavarzian, Stefan J. Green, Phillip A. Engen et al. · Movement Disorders | 16 Jul 2015 | 1,335 |
| 5 | The Epidemiology of Corticosteroid-Induced Osteoporosis: a Meta-analysis Tjeerd Pieter van Staa, Tjeerd Pieter van Staa, T. P. van Staa et al. · Osteoporosis International | Oct 2002 | 1,308 |
| 6 | Polymeric Micelles in Anticancer Therapy: Targeting, Imaging and Triggered Release Chris Oerlemans, Wouter Bult, Mariska Bos et al. · Pharmaceutical Research | 19 Aug 2010 | 944 |
| 7 | Nitric Oxide in Health and Disease of the Respiratory System Fabio Luigi Massimo Ricciardolo, Peter J. Sterk, Benjamin M Gaston et al. · Physiological Reviews | Jul 2004 | 906 |
| 8 | Prolonged QTc Interval and Risk of Sudden Cardiac Death in a Population of Older Adults Sabine M. J. M. Straus, Jan A. Kors, Marie L. De Bruin et al. · Journal of the American College of Cardiology | 2006 | 845 |
| 9 | Curcumin nanoformulations: A review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment Ornchuma Naksuriya, Siriporn Okonogi, Raymond Michel Schiffelers et al. · Biomaterials | 15 Jan 2014 | 842 |
| 10 | Complement Is Activated by IgG Hexamers Assembled at the Cell Surface Christoph A. Diebolder, Frank J M Beurskens, Rob N. de Jong et al. · Science | 13 Mar 2014 | 813 |
| 11 | The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers Javier Muñoz, Daniel E. Stange, Arnout G. Schepers et al. · The EMBO Journal | 12 Jun 2012 | 807 |
| 12 | Photodynamic Therapy in Oncology Martijn Triesscheijn, Paul Baas, Jan H.M. Schellens et al. · The Oncologist | Oct 2006 | 742 |
| 13 | Protein Instability in Poly(Lactic-co-Glycolic Acid) Microparticles Marco van de Weert, Wim E. Hennink, Wim Jiskoot · Pharmaceutical Research | Oct 2000 | 707 |
| 14 | Oral corticosteroids and fracture risk: relationship to daily and cumulative doses Tjeerd Pieter van Staa, Hubert G. M. Leufkens, Lucien Abenhaim et al. · Lara D. Veeken | Dec 2000 | 702 |
| 15 | Rare and low-frequency coding variants alter human adult height Eirini Marouli et al. · Nature | 31 Jan 2017 | 665 |
| 16 | A Genotype-Guided Strategy for Oral P2Y 12 Inhibitors in Primary PCI Daniel M.F. Claassens, Gerrit J.A. Vos, Thomas O. Bergmeijer et al. · New England Journal of Medicine | 3 Sep 2019 | 649 |
| 17 | Structure-Immunogenicity Relationships of Therapeutic Proteins Suzanne Hermeling, Daan J.A. Crommelin, Huub Schellekens et al. · Pharmaceutical Research | 27 May 2004 | 626 |
| 18 | Pro- and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells Meng Li, Betty C. A. M. van Esch, Gerry T. M. Wagenaar et al. · European Journal of Pharmacology | 9 May 2018 | 623 |
| 19 | Chitosan-based delivery systems for protein therapeutics and antigens Maryam Amidi, Enrico Mastrobattista, Wim Jiskoot et al. · Advanced Drug Delivery Reviews | 17 Nov 2009 | 617 |
| 20 | Drug binding to human alpha-1-acid glycoprotein in health and disease. Joel M. Kremer, Jaap Wilting, Lambert H.M. Janssen · Pharmacological Reviews | Mar 1988 | 583 |
| 21 | Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors Kimberley M. Heinhuis, Willeke Ros, Marleen Kok et al. · Annals of Oncology | 3 Jan 2019 | 575 |
| 22 | Inflammatory Disease Processes and Interactions with Nutrition Philip C. Calder et al. · British Journal Of Nutrition | May 2009 | 575 |
| 23 | A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study Jesse Joachim Swen et al. · The Lancet | Feb 2023 | 564 |
| 24 | Sheddable Coatings for Long-Circulating Nanoparticles Birgit Romberg, Wim E. Hennink, Gert Storm · Pharmaceutical Research | 5 Jun 2007 | 555 |
| 25 | Tumour-targeted nanomedicines: principles and practice Twan Lammers, Wim E. Hennink, G. Storm · British Journal of Cancer | 22 Jul 2008 | 542 |
| 26 | Addressing the Cold Reality of mRNA Vaccine Stability Daan J.A. Crommelin, Thomas J. Anchordoquy, David B. Volkin et al. · Journal of Pharmaceutical Sciences | 13 Dec 2020 | 531 |
| 27 | Use of oral glucocorticoids and risk of cardiovascular and cerebrovascular disease in a population based case–control study Patrick Cyriel Souverein, Anick Bérard, Tjeerd Pieter van Staa et al. · Heart | 14 Jul 2004 | 486 |
| 28 | A Compositional Look at the Human Gastrointestinal Microbiome and Immune Activation Parameters in HIV Infected Subjects Ece Mutlu, Ali Keshavarzian, John Losurdo et al. · PLoS Pathogens | 20 Feb 2014 | 483 |
| 29 | Amine Coupling Through EDC/NHS: A Practical Approach Marcel J.E. Fischer · Methods in molecular biology | 2010 | 481 |
| 30 | Epidemiology of Adverse Drug Reactions in Europe: A Review of Recent Observational Studies Jacoline C. Bouvy, Marie L. De Bruin, Marc A. Koopmanschap · Drug Safety | 30 Mar 2015 | 478 |
| 31 | An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation Ege Can Şerefoğlu, Chris G. McMahon, Marcel D. Waldinger et al. · The Journal of Sexual Medicine | 22 May 2014 | 470 |
| 32 | RGD-based strategies for selective delivery of therapeutics and imaging agents to the tumour vasculature Kai Temming, Raymond Michel Schiffelers, Grietje Molema et al. · Drug Resistance Updates | 24 Nov 2005 | 467 |
| 33 | Adverse drug events in hospitalized patients Patricia M. L. A. van den Bemt, Toine C. G. Egberts, Albert W. Lenderink et al. · European Journal of Clinical Pharmacology | 13 Apr 1999 | 462 |
| 34 | Estimating interaction on an additive scale between continuous determinants in a logistic regression model Mirjam J. Knol, Ingeborg van der Tweel, Diederick E. Grobbee et al. · International Journal of Epidemiology | 27 Aug 2007 | 457 |
| 35 | An Update of the International Society of Sexual Medicine's Guidelines for the Diagnosis and Treatment of Premature Ejaculation (PE) Stanley E. Althof, Chris G. McMahon, Marcel D. Waldinger et al. · Sexual Medicine | 22 May 2014 | 446 |
| 36 | DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis Linda M. Henricks et al. · The Lancet Oncology | 19 Oct 2018 | 442 |
| 37 | Altered gut microbiota and activity in a murine model of autism spectrum disorders Caroline G. M. de Theije, Harm Wopereis, Mohamed Ramadan et al. · Brain Behavior and Immunity | 11 Dec 2013 | 441 |
| 38 | Is HIV a Model of Accelerated or Accentuated Aging? Sophia Pathai, Hendren Bajillan, ALAN L. LANDAY et al. · The Journals of Gerontology Series A | 24 Oct 2013 | 424 |
| 39 | The battle of “nano” paclitaxel Alexandros Marios Sofias, Michael Dunne, Gert Storm et al. · Advanced Drug Delivery Reviews | 28 Feb 2017 | 408 |
| 40 | Exploring Braak’s Hypothesis of Parkinson’s Disease Carmen D. Rietdijk, Paula Perez‐Pardo, Johan Garssen et al. · Frontiers in Neurology | 13 Feb 2017 | 401 |
| 41 | PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study Amand Floriaan Schmidt et al. · The Lancet Diabetes & Endocrinology | 28 Nov 2016 | 393 |
| 42 | Circadian rhythms and the gut microbiota: from the metabolic syndrome to cancer Faraz Bishehsari, Robin M. Voigt, Ali Keshavarzian · Nature Reviews Endocrinology | 26 Oct 2020 | 388 |
| 43 | Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data Didier Meulendijks et al. · The Lancet Oncology | 25 Oct 2015 | 384 |
| 44 | Bridging the efficacy–effectiveness gap: a regulator's perspective on addressing variability of drug response Hans‐Georg Eichler, Eric C. Abadie, Alasdair M. Breckenridge et al. · Nature Reviews Drug Discovery | Jul 2011 | 381 |
| 45 | What Is Real-World Data? A Review of Definitions Based on Literature and Stakeholder Interviews Amr Makady, Anthonius de Boer, Hans L. Hillege et al. · Value in Health | 11 May 2017 | 379 |
| 46 | Validation of pharmacy records in drug exposure assessment Hong S. Lau, Anthonius de Boer, K. S. Beuning et al. · Journal of Clinical Epidemiology | May 1997 | 376 |
| 47 | A large fraction of HLA class I ligands are proteasome-generated spliced peptides Juliane Liepe, Fabio Marino, John Sidney et al. · Science | 20 Oct 2016 | 369 |
| 48 | Relevance of methodological design for the interpretation of efficacy of drug treatment of premature ejaculation: a systematic review and meta-analysis Marcel D. Waldinger, Aeilko Having Zwinderman, Dave H. Schweitzer et al. · International Journal of Impotence Research | 12 Feb 2004 | 369 |
| 49 | Incidence and Natural History of Paget's Disease of Bone in England and Wales Tjeerd Pieter van Staa, Peter L. Selby, Hubert G. M. Leufkens et al. · Journal of Bone and Mineral Research | Mar 2002 | 369 |
| 50 | Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man Jan J.P. Bogaards, Marc Bertrand, Peter F. Jackson et al. · Xenobiotica | 2000 | 368 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.