| 1 |
Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II–Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3
Yong‐Chen Lu, Linda L. Parker, Tangying Lu et al. · Journal of Clinical Oncology
Open access |
15 Aug 2017 |
280 |
| 2 |
Visualization of self-delivering hydrophobically modified siRNA cellular internalization
Socheata Ly, Deanna M. Navaroli, Marie-Cécile Didiot et al. · Nucleic Acids Research
Open access |
24 Oct 2016 |
133 |
| 3 |
Rabenosyn-5 defines the fate of the transferrin receptor following clathrin-mediated endocytosis
Deanna M. Navaroli, Karl D. Bellve, Clive Standley et al. · Proceedings of the National Academy of Sciences
Open access |
30 Jan 2012 |
93 |
| 4 |
The TeGenero Incident and the Duff Report Conclusions: A Series of Unfortunate Events or an Avoidable Event?
Christopher J. Horvath, Mark Milton · Toxicologic Pathology
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24 Feb 2009 |
87 |
| 5 |
Specificity and functionality of microRNA inhibitors
Barbara Robertson, Andrew B Dalby, Jon M. Karpilow et al. · Silence
Open access |
Apr 2010 |
81 |
| 6 |
Novel Hydrophobically Modified Asymmetric RNAi Compounds (sd-rxRNA) Demonstrate Robust Efficacy in the Eye
MICHAEL J. BYRNE, Radouil T. Tzekov, Yi Wang et al. · Journal of Ocular Pharmacology and Therapeutics
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Nov 2013 |
78 |
| 7 |
The EMEA Guideline on First-in-Human Clinical Trials and Its Impact on Pharmaceutical Development
Mark Milton, Christopher J. Horvath · Toxicologic Pathology
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26 Feb 2009 |
74 |
| 8 |
Self-Delivering RNAi Targeting PD-1 Improves Tumor-Specific T Cell Functionality for Adoptive Cell Therapy of Malignant Melanoma
Maarten Alexander Ligtenberg, Yago Pico de Coaña, Taisia Shmushkovich et al. · Molecular Therapy
Open access |
13 Apr 2018 |
51 |
| 9 |
Using pulse field gradient NMR diffusion measurements to define molecular size distributions in glycan preparations
Michelle C. Miller, Anatole A. Klyosov, David Platt et al. · Carbohydrate Research
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18 Apr 2009 |
29 |
| 10 |
Linear growth and bone maturation are unaffected by 1 year of therapy with inhaled flunisolide hydrofluoroalkane in prepubescent children with mild persistent asthma: A randomized, double-blind, placebo-controlled trial
George W. Bensch, Leon S. Greos, Sandra M. Gawchik et al. · Annals of Allergy Asthma & Immunology
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7 Sep 2011 |
19 |
| 11 |
Lyophilization of Nonviral Gene Delivery Systems
Steven Allison, Thomas J. Anchordoquy · Humana Press eBooks
Book chapter |
15 Nov 2003 |
15 |
| 12 |
Cloning of ground-state intestinal stem cells from endoscopic biopsy samples
Marcin Dulęba et al. · Nature Protocols
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Apr 2020 |
12 |
| 13 |
Diphencyprone Treatment of Alopecia Areata: Postulated Mechanism of Action and Prospects for Therapeutic Synergy with RNA Interference
Karen G. Bulock, James P. Cardia, Pamela A. Pavco et al. · Journal of Investigative Dermatology Symposium Proceedings
Conference paperOpen access |
Nov 2015 |
9 |
| 14 |
Potent and systematic RNAi mediated silencing with single oligonucleotide compounds
Jennifer L. Lapierre, William E. Salomon, James P. Cardia et al. · RNA
Open access |
14 Apr 2011 |
8 |
| 15 |
Clinical Characterization of Nursing Facility Residents With Chronic Obstructive Pulmonary Disease
H. Edward Davidson, Peter Radlowski, Lisa Han et al. · The Senior Care Pharmacist
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21 Apr 2021 |
6 |
| 16 |
Self-delivering RNAi immunotherapeutic PH-762 silences PD-1 to generate local and abscopal antitumor efficacy
Benjamin Cuiffo, Melissa Maxwell, Dingxue Yan et al. · Frontiers in Immunology
Open access |
4 Dec 2024 |
5 |
| 17 |
INTASYL self-delivering RNAi decreases TIGIT expression, enhancing NK cell cytotoxicity: a potential application to increase the efficacy of NK adoptive cell therapy against cancer
Melissa Maxwell, Dingxue Yan, Brianna Rivest et al. · Cancer Immunology Immunotherapy
Open access |
3 Oct 2024 |
5 |
| 18 |
Early diagnosis and successful long-term management of a rare, severe lysosomal acid lipase deficiency/Wolman disease patient: Infancy to age five
Antoine Cossette, Julie Castilloux, Chantal Bouffard et al. · Canadian Liver Journal
Open access |
3 Jun 2022 |
3 |
| 19 |
Evaluation of the Path to Diagnosis and Time to Treatment in Patients with Light-Chain Amyloidosis Using the Komodo Claims Database
Julia Catini, Quan V. Doan, Jennifer Evans et al. · Blood
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15 Nov 2022 |
2 |
| 20 |
Self-delivering RNAi compounds as therapeutic agents in the central nervous system to enhance axonal regeneration after injury
Sarah A. Woller, Joerg Ruschel, Barbara Morquette et al. · iScience
Open access |
10 May 2022 |
2 |
| 21 |
O-03.05 Targeting PD-1 with self-delivering RNAi: preclinical advances and ongoing clinical evaluation in intratumoral immunotherapy
Mary Claire Maxwell, Larry T. Mahoney, Mary C. Spellman · Oral Presentations
Conference paperOpen access |
24 Mar 2025 |
1 |
| 22 |
Self-Delivering RNAi Compounds for Reduction of Hyperpigmentation
Melissa Maxwell, Katherine Holton, Richard J. Looby et al. · Clinical Cosmetic and Investigational Dermatology
Open access |
Dec 2024 |
1 |
| 23 |
496 RXI-109 treatment to reduce the formation of hypertrophic dermal scars
Laurie A. Barefoot, M. Survi, James P. Cardia et al. · Journal of Investigative Dermatology
Open access |
19 Apr 2018 |
1 |
| 24 |
0470 Clinical study of intratumoral PH-762 targeting PD-1 for cutaneous carcinomas
Mary C. Spellman, Katharine Furst, Larry T. Mahoney · Journal of Investigative Dermatology
Open access |
21 Jul 2025 |
0 |
| 25 |
O-13.04 SIlencing BRD4 to increase NK cell activity for adoptive cell therapy: a novel self-delivering RNAi approach
Melissa Maxwell, Elfriede Noeßner · Oral Presentations
Conference paperOpen access |
24 Mar 2025 |
0 |
| 26 |
283 Intratumoral PH-762 targeting PD-1 for cutaneous carcinoma
Mary C. Spellman, K. Furst, Larry T. Mahoney · Journal of Investigative Dermatology
Open access |
19 Jul 2024 |
0 |
| 27 |
575 INTASYL self-delivering RNAi: A flexible platform to treat dermatological malignancies
Melissa Maxwell, Dingxue Yan, B. Rivest et al. · Journal of Investigative Dermatology
Open access |
19 Jul 2024 |
0 |
| 28 |
576 INTASYL PH-762: Intratumoral immunotherapy targeting PD-1
Melissa Maxwell, Dingxue Yan, Andrew R. Boone et al. · Journal of Investigative Dermatology
Open access |
19 Jul 2024 |
0 |
| 29 |
P01.03 RNAi mediated PD-1 knockdown induces a TCF-1 positive population in activated human CD8 T cells with stem-like associated marker profile
AS Herbstritt, Melissa Maxwell, Dingxue Yan et al. · Poster presentations
Conference paperOpen access |
Sep 2022 |
0 |
| 30 |
1257 Topical application of self-delivering RNAi (sd-rxRNA®) compounds for reduction of hyperpigmentation
Melissa Maxwell, G Dispersyn, Katherine Holton et al. · Journal of Investigative Dermatology
Open access |
19 Apr 2018 |
0 |
| 31 |
1792P Dual targeting PD-1 and BRD4 with INTASYL self-delivering RNAi elicits persistent anti-tumor immunity in-vivo following complete resolution of tumors
Benjamin Cuiffo, Melissa Maxwell, Dingxue Yan et al. · Annals of Oncology
Open access |
Sep 2021 |
0 |
| 32 |
P01.03 Targeting diaclyglycerol kinase alpha and zeta by self delivering RNAi to optimize tlymphocytes for adoptive therapy of solid tumors
AS Herbstritt, Melissa Maxwell, Dingxue Yan et al. · Poster presentations
Conference paperOpen access |
Oct 2021 |
0 |
| 33 |
Formulation and Release of sd-rxRNA® from a Cross-linked, Thiolated CMHA-based Film for Topical Delivery to Reduce the Formation of Corneal Scarring
MICHAEL J. BYRNE, Hee‐Kyoung Lee, James P. Cardia et al. · Investigative Ophthalmology & Visual Science
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11 Jun 2015 |
0 |
| 34 |
490 Samcyprone (diphenylcyclopropenone ointment) for the treatment of common warts
Karen G. Bulock, James P. Cardia, M. Survi et al. · Journal of Investigative Dermatology
Open access |
19 Apr 2018 |
0 |
| 35 |
“What’s up over the ditch?” a look at NP practice in New Zealand
Diane Williams · The Journal for Nurse Practitioners
Open access |
Jul 2017 |
0 |
| 36 |
810 Topical application of self-delivering RNAi (sd-rxRNA®) compounds for reduction of hyperpigmentation
Melissa Maxwell, Katherine Holton, James P. Cardia et al. · Journal of Investigative Dermatology
Open access |
12 Apr 2017 |
0 |
| 37 |
756 Prevention of uvr induced mmp1 upregulation with mmp1 targeting self-delivering rnai (sd-rxrna ® ) compounds may reduce the effects of skin photoaging
Katherine Holton, Melissa Maxwell, MICHAEL J. BYRNE et al. · Journal of Investigative Dermatology
Open access |
12 Apr 2017 |
0 |
| 38 |
sd-rxRNA®: Self-Delivering RNAi Compounds Show Potential for Corneal Indications Following Topical Application
MICHAEL J. BYRNE, Melissa Maxwell, Richard J. Looby et al. · Investigative Ophthalmology & Visual Science
Open access |
26 Sep 2016 |
0 |
| 39 |
651 Self-delivering RNAi compounds for reduction of hyperpigmentation
Melissa Maxwell, Katherine Holton, James P. Cardia et al. · Journal of Investigative Dermatology
Open access |
28 Apr 2016 |
0 |
| 40 |
582 Potent self-delivering rnai compounds targeting MMP1 reduce UVR induced MMP1 upregulation
Katherine Holton, Melissa Maxwell, James P. Cardia et al. · Journal of Investigative Dermatology
Open access |
28 Apr 2016 |
0 |
| 41 |
MDM2 Targeting sd-rxRNA® for Retinoblastoma Therapy
Kevin Stachelek, James P. Cardia, Dong-Lai Qi et al. · Investigative Ophthalmology & Visual Science
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11 Jun 2015 |
0 |