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Generation of glyco‐engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human‐like N‐glycan structure
Richard Strasser, Johannes Stadlmann, Matthias Schähs et al. · Plant Biotechnology Journal
Open access |
13 Mar 2008 |
531 |
| 2 |
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
Alexandra Trkola, Herbert Kuster, Peter Rusert et al. · Nature Medicine
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8 May 2005 |
514 |
| 3 |
Liposome Technology for Industrial Purposes
Andreas Wagner, Karola Vorauer‐Uhl · Journal of Drug Delivery
Open access |
5 Dec 2010 |
437 |
| 4 |
Regulatory approval and a first‐in‐human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants
Julian K‐C. et al. · Plant Biotechnology Journal
Open access |
3 Jul 2015 |
265 |
| 5 |
In Planta Protein Sialylation through Overexpression of the Respective Mammalian Pathway
Alexandra Castilho, Richard Strasser, Johannes Stadlmann et al. · Journal of Biological Chemistry
Open access |
20 Mar 2010 |
231 |
| 6 |
Process parameter shifting: Part I. Effect of DOT, pH, and temperature on the performance of Epo‐Fc expressing CHO cells cultivated in controlled batch bioreactors
Evelyn Trummer, Katharina Fauland, Silke Seidinger et al. · Biotechnology and Bioengineering
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30 May 2006 |
220 |
| 7 |
Improved Virus Neutralization by Plant-produced Anti-HIV Antibodies with a Homogeneous β1,4-Galactosylated N-Glycan Profile
Richard Strasser, Alexandra Castilho, Johannes Stadlmann et al. · Journal of Biological Chemistry
Open access |
29 May 2009 |
179 |
| 8 |
Recombinant antibody 2G12 produced in maize endosperm efficiently neutralizes HIV‐1 and contains predominantly single‐GlcNAc N ‐glycans
Thomas W. Rademacher, M. Sack, Elsa Arcalís et al. · Plant Biotechnology Journal
Open access |
4 Nov 2007 |
174 |
| 9 |
Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques
Christiane Moog, N Dereuddre-Bosquet, J-L Teillaud et al. · Mucosal Immunology
Open access |
17 Apr 2013 |
159 |
| 10 |
Cost-effective production of a vaginal protein microbicide to prevent HIV transmission
Koreen Ramessar, Thomas W. Rademacher, M. Sack et al. · Proceedings of the National Academy of Sciences
Open access |
3 Mar 2008 |
158 |
| 11 |
Complete Protection of Neonatal Rhesus Macaques against Oral Exposure to Pathogenic Simian‐Human Immunodeficiency Virus by Human Anti‐HIV Monoclonal Antibodies
Flavia Ferrantelli, Robert A. Rasmussen, Kathleen A. Buckley et al. · The Journal of Infectious Diseases
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2 Jun 2004 |
158 |
| 12 |
A phase 1 dose-escalation study on the safety, tolerability and activity of liposomal curcumin (Lipocurc™) in patients with locally advanced or metastatic cancer
Richard Greil, Sigrun Greil‐Ressler, Lukas Weiß et al. · Cancer Chemotherapy and Pharmacology
Open access |
3 Aug 2018 |
139 |
| 13 |
A phase I trial with two human monoclonal antibodies (hMAb 2F5, 2G12) against HIV-1
Christine Armbruster, Gabriela M. Stiegler, Brigitta A. Vcelar et al. · AIDS
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2002 |
130 |
| 14 |
Adjunctive Passive Immunotherapy in Human Immunodeficiency Virus Type 1-Infected Individuals Treated with Antiviral Therapy during Acute and Early Infection
Saurabh Mehandru, Brigitta A. Vcelar, Terri Wrin et al. · Journal of Virology
Open access |
9 Aug 2007 |
123 |
| 15 |
THE CROSSFLOW INJECTION TECHNIQUE: AN IMPROVEMENT OF THE ETHANOL INJECTION METHOD
Andreas Wagner, Karola Vorauer‐Uhl, Günther Kreismayr et al. · Journal of Liposome Research
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2002 |
122 |
| 16 |
Anti-neuroblastoma effect of ch14.18 antibody produced in CHO cells is mediated by NK-cells in mice
Yan Zeng, Stefan Fest, Renate Kunert et al. · Molecular Immunology
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8 Apr 2005 |
113 |
| 17 |
Post-exposure prophylaxis with human monoclonal antibodies prevented SHIV89.6P infection or disease in neonatal macaques
Flavia Ferrantelli, Regina Hofmann‐Lehmann, Robert A. Rasmussen et al. · AIDS
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Feb 2003 |
107 |
| 18 |
Liposomes produced in a pilot scale: production, purification and efficiency aspects
Andreas Wagner, Karola Vorauer‐Uhl, Hermann W. D. Katinger · European Journal of Pharmaceutics and Biopharmaceutics
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Sep 2002 |
101 |
| 19 |
In Vivo and In Vitro Escape from Neutralizing Antibodies 2G12, 2F5, and 4E10
Amapola Manrique, Peter Rusert, Béda Joos et al. · Journal of Virology
Open access |
14 Jun 2007 |
95 |
| 20 |
Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Synthesis
David Reinhart, Lukas Damjanovic, Christian Kaisermayer et al. · Biotechnology Journal
Open access |
27 Apr 2018 |
93 |
| 21 |
Functional analysis of the broadly neutralizing human anti‐HIV‐1 antibody 2F5 produced in transgenic BY‐2 suspension cultures
M. Sack, Antje Paetz, Renate Kunert et al. · The FASEB Journal
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27 Feb 2007 |
90 |
| 22 |
Inhibition of In Vivo HIV Infection in Humanized Mice by Gene Therapy of Human Hematopoietic Stem Cells with a Lentiviral Vector Encoding a Broadly Neutralizing Anti-HIV Antibody
Aviva Joseph, Jian Hua Zheng, Ken Chen et al. · Journal of Virology
Open access |
21 Apr 2010 |
84 |
| 23 |
Generation of Biologically Active Multi-Sialylated Recombinant Human EPOFc in Plants
Alexandra Castilho, Laura Neumann, Pia Gattinger et al. · PLoS ONE
Open access |
25 Jan 2013 |
82 |
| 24 |
Ch14.18 antibody produced in CHO cells in relapsed or refractory Stage 4 neuroblastoma patients
Ruth Lydia Ladenstein, Silke Weixler, Bianca Baykan et al. · mAbs
Open access |
31 May 2013 |
81 |
| 25 |
Virus Isolates during Acute and Chronic Human Immunodeficiency Virus Type 1 Infection Show Distinct Patterns of Sensitivity to Entry Inhibitors
Peter Rusert, Herbert Kuster, Béda Joos et al. · Journal of Virology
Open access |
15 Jun 2005 |
80 |
| 26 |
Neutralization Profiles of Newly Transmitted Human Immunodeficiency Virus Type 1 by Monoclonal Antibodies 2G12, 2F5, and 4E10
Saurabh Mehandru, Terri Wrin, Justin Galovich et al. · Journal of Virology
Open access |
24 Nov 2004 |
78 |
| 27 |
Process parameter shifting: Part II. Biphasic cultivation—A tool for enhancing the volumetric productivity of batch processes using Epo‐Fc expressing CHO cells
Evelyn Trummer, Katharina Fauland, Silke Seidinger et al. · Biotechnology and Bioengineering
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30 May 2006 |
76 |
| 28 |
Antibodies to conserved epitopes of the HIV-1 envelope in sera from long-term non-progressors: prevalence and association with neutralizing activity
Martine Braibant, S. Brunet, Dominique G. Costagliola et al. · AIDS
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21 Sep 2006 |
76 |
| 29 |
Liposomal Recombinant Human Superoxide Dismutase for the Treatment of Peyronie's Disease: A Randomized Placebo-Controlled Double-Blind Prospective Clinical Study
CLAUS R. RIEDL, Peter Sternig, Günter Gallè et al. · European Urology
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12 May 2005 |
66 |
| 30 |
Glycan profiles of the 27 N-glycosylation sites of the HIV envelope protein CN54gp140
Martin Pabst, Martina Wei-Fen Chang, Johannes Stadlmann et al. · Biological Chemistry
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Aug 2012 |
63 |
| 31 |
Long-Term Multiple-Dose Pharmacokinetics of Human Monoclonal Antibodies (MAbs) against Human Immunodeficiency Virus Type 1 Envelope gp120 (MAb 2G12) and gp41 (MAbs 4E10 and 2F5)
Béda Joos, Alexandra Trkola, Herbert Kuster et al. · Antimicrobial Agents and Chemotherapy
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26 Apr 2006 |
62 |
| 32 |
Biochemical characterization of rhEpo-Fc fusion protein expressed in CHO cells
Kornelia Schriebl, Evelyn Trummer, Christine Lattenmayer et al. · Protein Expression and Purification
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16 Jun 2006 |
60 |
| 33 |
In Vivo Efficacy of Human Immunodeficiency Virus Neutralizing Antibodies: Estimates for Protective Titers
Alexandra Trkola, Herbert Kuster, Peter Rusert et al. · Journal of Virology
Open access |
22 Nov 2007 |
56 |
| 34 |
Characterisation of recombinant CHO cell lines by investigation of protein productivities and genetic parameters
Christine Lattenmayer, Evelyn Trummer, Kornelia Schriebl et al. · Journal of Biotechnology
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31 Dec 2006 |
54 |
| 35 |
Sustained release of proteins from a modified vaginal ring device
Ryan J. Morrow, A. David Woolfson, Louise Donnelly et al. · European Journal of Pharmaceutics and Biopharmaceutics
Open access |
4 Nov 2010 |
53 |
| 36 |
HIV-1 mutants escaping neutralization by the human antibodies 2F5, 2G12, and 4E10: in vitro experiments versus clinical studies
Sabine Nakowitsch, Heribert Quendler, Helga Fekete et al. · AIDS
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31 Oct 2005 |
52 |
| 37 |
Expression of functionally active sialylated human erythropoietin in plants
Jakub Jeż, Alexandra Castilho, Josephine Grass et al. · Biotechnology Journal
Open access |
17 Jan 2013 |
50 |
| 38 |
Heterologous protein production using euchromatin-containing expression vectors in mammalian cells
Katalin Zboray, Wolfgang Sommeregger, Edith Bogner et al. · Nucleic Acids Research
Open access |
14 May 2015 |
50 |
| 39 |
Reassessment of autoreactivity of the broadly neutralizing HIV antibodies 4E10 and 2F5 and retrospective analysis of clinical safety data
Brigitta A. Vcelar, Gabriela M. Stiegler, Hermann Maximilian Wolf et al. · AIDS
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Oct 2007 |
48 |
| 40 |
Potent Cross‐Group Neutralization of Primary Human Immunodeficiency Virus Isolates with Monoclonal Antibodies—Implications for Acquired Immunodeficiency Syndrome Vaccine
Flavia Ferrantelli, Moiz Kitabwalla, Robert A. Rasmussen et al. · The Journal of Infectious Diseases
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2004 |
46 |
| 41 |
Live attenuated influenza viruses produced in a suspension process with avian AGE1.CR.pIX cells
Verena Lohr, Yvonne Genzel, Ingo Jordan et al. · BMC Biotechnology
Open access |
30 Oct 2012 |
43 |
| 42 |
Reepithelialization of experimental scalds effected by topically applied superoxide dismutase: controlled animal studies
Karola Vorauer‐Uhl, Eckhard Fürnschlief, Andreas Wagner et al. · Wound Repair and Regeneration
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Nov 2002 |
43 |
| 43 |
ENHANCED PROTEIN LOADING INTO LIPOSOMES BY THE MULTIPLE CROSSFLOW INJECTION TECHNIQUE
Andreas Wagner, Karola Vorauer‐Uhl, Günther Kreismayr et al. · Journal of Liposome Research
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2002 |
42 |
| 44 |
Analysis of recombinant human follicle-stimulating hormone (FSH) by mass spectrometric approaches
Josephine Grass, Martin Pabst, Martina Wei-Fen Chang et al. · Analytical and Bioanalytical Chemistry
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2 Apr 2011 |
42 |
| 45 |
Proteomic differences in recombinant CHO cells producing two similar antibody fragments
Wolfgang Sommeregger, Patrick Mayrhofer, Willibald Steinfellner et al. · Biotechnology and Bioengineering
Open access |
25 Feb 2016 |
40 |
| 46 |
High level expression of a promising anti-idiotypic antibody fragment vaccine against HIV-1 in Pichia pastoris
Johannes S. Gach, Michael Maurer, Rainer Hahn et al. · Journal of Biotechnology
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11 Jan 2007 |
40 |
| 47 |
Repeated vaginal administration of trimeric HIV-1 clade C gp140 induces serum and mucosal antibody responses
Martin P Cranage, Caroline Fraser, Zoe Stevens et al. · Mucosal Immunology
Open access |
9 Sep 2009 |
39 |
| 48 |
Escape the Fake: Development and Evaluation of an Augmented Reality Escape Room Game for Fighting Fake News
Irina Paraschivoiu, Josef Buchner, Robert Praxmarer et al.
Conference paper |
15 Oct 2021 |
37 |
| 49 |
Time dependence of protective post-exposure prophylaxis with human monoclonal antibodies against pathogenic SHIV challenge in newborn macaques
Flavia Ferrantelli, Kathleen A. Buckley, Robert A. Rasmussen et al. · Virology
Open access |
26 Sep 2006 |
37 |
| 50 |
Comparison of carbamylated erythropoietin-FC fusion protein and recombinant human erythropoietin during porcine aortic balloon occlusion-induced spinal cord ischemia/reperfusion injury
Florian Simon, Angelika Scheuerle, Michael Gröger et al. · Intensive Care Medicine
Open access |
15 Jul 2011 |
36 |