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Most cited papers from Protagonist Therapeutics (United States)

What are the most cited papers from Protagonist Therapeutics (United States)?

The most cited paper from Protagonist Therapeutics (United States) is "Discovery and Characterization of a Potent Interleukin-6 Binding Peptide with Neutralizing Activity In Vivo" (Sheila H. Ranganath et al., 2015), with 44 citations. Next come "JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans" (42) and "Rusfertide for the treatment of iron overload in HFE-related haemochromatosis: an open-label, multicentre, proof-of-concept phase 2 trial" (40).

Showing 50 of 88 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Discovery and Characterization of a Potent Interleukin-6 Binding Peptide with Neutralizing Activity In Vivo Sheila H. Ranganath et al. · PLoS ONE Open access 10 Nov 2015 44
2 JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans Anne M. Fourie et al. · Scientific Reports Open access 30 Jul 2024 42
3 Rusfertide for the treatment of iron overload in HFE-related haemochromatosis: an open-label, multicentre, proof-of-concept phase 2 trial Kris V. Kowdley, Nishit B. Modi, Kevork Minas Peltekian et al. · ˜The œLancet. Gastroenterology & hepatology 17 Oct 2023 40
4 PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis William J. Sandborn, Larry C. Mattheakis, Nishit B. Modi et al. · Gastroenterology Open access 30 Aug 2021 37
5 Preclinical Serological Signatures are Associated With Complicated Crohn’s Disease Phenotype at Diagnosis Rok Seon Choung, Francesca Petralia, Joana Torres et al. · Clinical Gastroenterology and Hepatology Open access 12 Feb 2023 29
6 Mercaptopurine for the Treatment of Ulcerative Colitis: A Randomized Placebo-Controlled Trial Mark Löwenberg, Adriaan Volkers, Sara van Gennep et al. · Journal of Crohn s and Colitis Open access 27 Feb 2023 26
7 Real-world treatments and thrombotic events in polycythemia vera patients in the USA Srđan Verstovšek, Naveen Pemmaraju, Nancy L. Reaven et al. · Annals of Hematology Open access 13 Jan 2023 25
8 751 Safety, Tolerability, and Pharmacokinetics of PTG-200, an Oral GI-Restricted Peptide Antagonist of IL-23 Receptor, in Normal Healthy Volunteers Xiaoli Cheng, Tien-Yi Lee, Grace A. Ledet et al. · The American Journal of Gastroenterology Oct 2019 17
9 Translational Pharmacokinetics of Icotrokinra, a Targeted Oral Peptide that Selectively Blocks Interleukin-23 Receptor and Inhibits Signaling Beverly Knight et al. · Dermatology and Therapy Open access 8 Jul 2025 16
10 Single‐ and Multiple‐Dose Pharmacokinetics and Pharmacodynamics of PN‐943, a Gastrointestinal‐Restricted Oral Peptide Antagonist of α4β7, in Healthy Volunteers Nishit B. Modi, Xiaoli Cheng, Larry C. Mattheakis et al. · Clinical Pharmacology in Drug Development Open access 4 May 2021 16
11 Contemporary Challenges in Polycythemia Vera Management From the Perspective of Patients and Physicians Andrew Tucker Kuykendall, Jennifer T. Fine, Marina Kremyanskaya · Clinical Lymphoma Myeloma & Leukemia Open access 16 Apr 2024 14
12 Clustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23 David T. Barkan, Xiaoli Cheng, Herodion Celino et al. · BMC Bioinformatics Open access 23 Nov 2016 14
13 NCCN Guidelines® Insights: Systemic Mastocytosis, Version 3.2024 Jason R. Gotlib et al. · Journal of the National Comprehensive Cancer Network Jun 2024 12
14 Pharmacokinetics, pharmacodynamics, and tolerability of an aqueous formulation of rusfertide ( PTG ‐300), a hepcidin mimetic, in healthy volunteers: A double‐blind first‐in‐human study Nishit B. Modi, Richard S. Shames, Jason D. Lickliter et al. · European Journal Of Haematology Open access 24 May 2024 10
15 Antibody-Drug Conjugates in Myeloid Leukemias Jayastu Senapati, Naval Guastad Daver, Naveen Pemmaraju · The Cancer Journal Nov 2022 8
16 Mechanism of Systemic Iron Regulation and Hematocrit Control By Hepcidin Peptidomimetics in Pre-Clinical Models Roopa Taranath, Larry C. Mattheakis, Li Zhao et al. · Blood 4 Nov 2020 6
17 Hepcidin Mimetic (PTG-300) Reverses Iron Deficiency While Controlling Hematocrit in Polycythemia Vera Patients Yelena Z. Ginzburg, Marina Kremyanskaya, Andrew Tucker Kuykendall et al. · Blood 5 Nov 2020 6
18 Defining scaffold geometries for interacting with proteins: geometrical classification of secondary structure linking regions Tran T. Tran, Christina Kulis, Steven M. Long et al. · Journal of Computer-Aided Molecular Design 22 Sep 2010 6
19 Physiological immunity or pathological autoimmunity — A question of balance Chai Ezerzer, Nicholas L. Harris · Autoimmunity Reviews 23 Mar 2007 6
20 Results from VERIFY, a phase 3, double-blind, placebo (PBO)-controlled study of rusfertide for treatment of polycythemia vera (PV). Andrew Tucker Kuykendall, Naveen Pemmaraju, Kristen Marie Pettit et al. · Journal of Clinical Oncology 4 Jun 2025 5
21 Pharmacokinetics and Pharmacodynamics of Rusfertide, a Hepcidin Mimetic, Following Subcutaneous Administration of a Lyophilized Powder Formulation in Healthy Volunteers Nishit B. Modi, Sarita Khanna, Sneha Rudraraju et al. · Drugs in R&D Open access 15 Nov 2024 5
22 1109 First-in-class oral peptide systemically targeting the IL-23 pathway A. Fourie, X. Cheng, L. Chang et al. · Journal of Investigative Dermatology Open access 17 Apr 2023 5
23 Real-World Treatments and Thrombotic Events in Polycythemia Vera Patients: A Retrospective Analysis between 2018-2019 in US Population Srđan Verstovšek, Ariel Han, Karin Chun Hayes et al. · Blood 5 Nov 2020 5
24 Ensino médio no Brasil: uma análise de melhores práticas e de políticas públicas Rose Mary Ferreira Lisboa da Silva, Cláudia Davis, Gisela Lobo B. P. Tartuce et al. · Revista Brasileira de Estudos Pedagógicos Open access 18 Jun 2019 5
25 P113 Model based predictions of the PTG-100 pharmacodynamic responses in ulcerative colitis patients Larry C. Mattheakis, Cecilia Fosser, Ramanatha Saralaya et al. · Journal of Crohn s and Colitis Open access 26 Jan 2017 5
26 The past decade of Genentech experience in elucidation of novel reaction mechanisms in drug metabolism Siamak Cyrus Khojasteh, Jasleen K. Sodhi, Jason S. Halladay et al. · Medicinal Chemistry Research 18 Aug 2023 4
27 Time to Endorse A Sensitive Method for Scoring Endoscopic Activity of Ulcerative Colitis in Clinical Research Neeraj Narula, Shahin Merat, David Liu et al. · Journal of Crohn s and Colitis 24 Aug 2022 4
28 Hepcidin Peptidomimetics - Oral Efficacy in Pre-Clinical Disease Model of Iron Overload Roopa Taranath et al. · Blood 4 Nov 2020 4
29 Rusfertide rapidly decreases hematocrit in patients with suboptimally controlled polycythemia vera Lee Ping Chew, Yelena Z. Ginzburg, Kamini Kirubamoorthy et al. · Leukemia Research Open access 29 Oct 2025 3
30 Multiple‐Dose Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Subcutaneous Rusfertide, a Hepcidin Mimetic, in Healthy Subjects Nishit B. Modi, Phillip V. Dinh, Ifode Ajari · Clinical Pharmacology in Drug Development Open access 29 Jan 2025 3
31 Quality of Life in Patients with Malignant Wounds Treated at a Wound Care Clinic Anna M. Chen, Stephen W. Dusza, Jacqueline Bromberg et al. · Research Square PreprintOpen access 2 Sep 2024 3
32 Netflix’s Maid and representations of masculinities through social class: a textual analysis. Melissa Boehm · Ámbitos Revista Internacional de Comunicación Open access 2023 3
33 730 Safety, Pharmacokinetics, and Pharmacodynamics of the Novel Oral Peptide Therapeutic PN-10943 (alpha4beta7 Integrin Antagonist) in Normal Healthy Volunteers Suneel Gupta, Xiaoli Cheng, Bittoo Kanwar et al. · The American Journal of Gastroenterology Oct 2019 3
34 Evaluation of Rusfertide, a Hepcidin Mimetic, on Cardiac Repolarization: A Randomized, Placebo- and Positive-Controlled Crossover Thorough QT Study in Healthy Participants Nishit B. Modi, Phillip V. Dinh, Hongqi Xue et al. · Clinical Therapeutics Open access Oct 2025 2
35 American Society of Hematology: building a comprehensive minority recruitment and retention professional program Margo Renee Rollins, Rahma M. Warsame, Melody Smith et al. · Blood Advances Open access 21 Nov 2024 2
36 P1016: RUSFERTIDE (PTG-300) IMPROVES POLYCYTHEMIA VERA (PV) RELATED SYMPTOMS IN PV PATIENTS Andrew Tucker Kuykendall, Marina Kremyanskaya, Yelena Z. Ginzburg et al. · HemaSphere Open access Aug 2023 2
37 O PROCESSO DE ENSINO-APRENDIZAGEM DA MATEMÁTICA NOS ANOS INICIAIS DO ENSINO FUNDAMENTAL: UMA CONSTRUÇÃO A PARTIR DE METODOLOGIAS ATIVAS Ana Jéssica Ribeiro, Edilson Raniere Gonçalves Pereira, Gerúnia Moraes Santos Carlos et al. · Revista Ibero-Americana de Humanidades, Ciências e Educação Open access 7 Dec 2021 2
38 Leonora Carrington en sus ochenta: la creación compartida Ana Rosa Domenella · Debate Feminista Open access Apr 1997 2
39 Reforma protestante e jacobinismo nos Quaderni del carcere: exemplos do “nacional-popular” Cláudio Edward dos Reis · Revista Aurora Open access 31 Dec 1969 2
40 An observational study of disease management in adult patients with polycythemia vera: results from a large U.S. claims database Andrew Tucker Kuykendall, Lucy Bellamy, Lopa Desai et al. · Expert Review of Hematology Open access 23 Jul 2025 1
41 CONSTRUINDO O FUTURO DA EDUCAÇÃO: A SINERGIA ENTRE ENSINO E TECNOLOGIA Bárbara Ribeiro Cardozo, Camila Caetano Tambara, Cristina Alice Pontes Estevão et al. · Revista Foco Open access 18 Oct 2023 1
42 A política de assistência estudantil em uma universidade pública: um estudo à luz das repercussões da COVID-19 Diego Souza de Medeiros, Jairo de Carvalho Guimarães · OBSERVATÓRIO DE LA ECONOMÍA LATINOAMERICANA Open access 11 Sep 2023 1
43 Metaficção Historiográfica em Desmundo, de Ana Miranda Gislaine da Silva Feitosa, Ana Carolina Negrão Berlini de Andrade · Scripta Open access 18 Nov 2022 1
44 É Heitor quem dá as ordens / Heitor calls the shots Renata Bittencourt · arte e ensaios Open access 31 Aug 2022 1
45 P1028: PTG-300 (RUSFERTIDE) TREATMENT INTERRUPTION REVERSES HEMATOLOGICAL GAINS AND RESTORES THERAPEUTIC BENEFIT ON REINITIATION IN SUBJECTS WITH POLYCYTHEMIA VERA Andrew Tucker Kuykendall, M. Kremyanskaya, Y. Ginsburg et al. · HemaSphere Open access Jun 2022 1
46 “¿Cuánto hace que dejaste de jugar a las muñecas?” Infancias y adolescencias militantes durante la última dictadura cívicomilitar en el Uruguay: el caso de Treinta y Tres Ana Laura Cafaro Mango · Tramas y Redes Open access Jun 2022 1
47 A utilização dos X-mencomo identidade gay no livro no presente, de Márcio El-jaick José Vilian Mangueira · Revista Darandina Open access 13 Sep 2019 1
48 El trabajo por proyectos es una promesa para la escuela en un país que sueña Dino Segura · Revista Rutas de formación prácticas y experiencias Open access Jul 2017 1
49 Resultados de um trabalho de parceria da Fundação Bradesco com as escolas públicas no Vale do Ribeira/SP Rose Neubauer, Yara Lúcia Espósito, Ana Luísa RestanI et al. · Estudos em Avaliação Educacional Open access 30 Aug 2010 1
50 A herança de Rubião Marcos Rogério Cordeiro Fernandes · O Eixo e a Roda Revista de Literatura Brasileira Open access 30 Jun 2008 1

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.