| 1 |
Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial
Mila Donker et al. · The Lancet Oncology
Open access |
15 Oct 2014 |
1,891 |
| 2 |
Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial
Carien L. Creutzberg, Wim LJ van Putten, Peter C.M. Koper et al. · The Lancet
|
Apr 2000 |
1,786 |
| 3 |
Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial
Remi A. Nout, VTHBM Smit, Hein Putter et al. · The Lancet
|
Mar 2010 |
1,154 |
| 4 |
Prophylactic Cranial Irradiation in Extensive Small-Cell Lung Cancer
Ben J. Slotman, Corinne Faivre Finn, Gijs W.P.M. Kramer et al. · New England Journal of Medicine
Open access |
15 Aug 2007 |
1,138 |
| 5 |
Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer—Combined Analysis of the PORTEC Cohorts
Ellen Stelloo, Remi A. Nout, Elisabeth M. Osse et al. · Clinical Cancer Research
|
22 Mar 2016 |
872 |
| 6 |
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
Kasper M. A. Rouschop, Twan van den Beucken, Ludwig Jerome Dubois et al. · Journal of Clinical Investigation
Open access |
28 Dec 2009 |
821 |
| 7 |
Randomized Controlled Trial of Resection Versus Radiotherapy After Induction Chemotherapy in Stage IIIA-N2 Non-Small-Cell Lung Cancer
Jan P. van Meerbeeck, Gijs W.P.M. Kramer, Paul E. Van Schil et al. · JNCI Journal of the National Cancer Institute
Open access |
20 Mar 2007 |
713 |
| 8 |
MRI-guided adaptive brachytherapy in locally advanced cervical cancer (EMBRACE-I): a multicentre prospective cohort study
Richard Pötter et al. · The Lancet Oncology
Open access |
29 Mar 2021 |
666 |
| 9 |
Patterns of Recurrence After Surgery Alone Versus Preoperative Chemoradiotherapy and Surgery in the CROSS Trials
Vera Oppedijk, Ate van der Gaast, J. Jan B. van Lanschot et al. · Journal of Clinical Oncology
|
14 Jan 2014 |
515 |
| 10 |
Single-dose brachytherapy versus metal stent placement for the palliation of dysphagia from oesophageal cancer: multicentre randomised trial
Marjolein Y.V. Homs, Ewout Willem Steyerberg, Wilhelmina M.H. Eijkenboom et al. · The Lancet
|
Oct 2004 |
510 |
| 11 |
Hypofractionated versus conventionally fractionated radiotherapy for patients with localised prostate cancer (HYPRO): final efficacy results from a randomised, multicentre, open-label, phase 3 trial
Luca Incrocci, Ruud C. Wortel, Wendimagegn Ghidey Alemayehu et al. · The Lancet Oncology
|
21 Jun 2016 |
483 |
| 12 |
Substantial lymph-vascular space invasion (LVSI) is a significant risk factor for recurrence in endometrial cancer – A pooled analysis of PORTEC 1 and 2 trials
Tjalling Bosse, Elke E.M. Peters, Carien L. Creutzberg et al. · European Journal of Cancer
Open access |
6 Jun 2015 |
453 |
| 13 |
Prediction of survival in patients with metastases in the spinal column
Yvette M. van der Linden, P. D. S. Dijkstra, Ernest J. A. Vonk et al. · Cancer
Open access |
8 Dec 2004 |
403 |
| 14 |
Survival after relapse in patients with endometrial cancer: results from a randomized trial☆
Carien L. Creutzberg, Wim L.J. van Putten, Peter C.M. Koper et al. · Gynecologic Oncology
|
25 Apr 2003 |
376 |
| 15 |
Hypofractionated versus conventionally fractionated radiotherapy for patients with prostate cancer (HYPRO): late toxicity results from a randomised, non-inferiority, phase 3 trial
Shafak Aluwini, Floris J. Pos, Erik C. Schimmel et al. · The Lancet Oncology
Open access |
8 Mar 2016 |
319 |
| 16 |
Randomized Study on Dose Escalation in Definitive Chemoradiation for Patients With Locally Advanced Esophageal Cancer (ARTDECO Study)
Maarten C.C.M. Hulshof, Elisabeth D. Geijsen, Tom Rozema et al. · Journal of Clinical Oncology
Open access |
8 Jun 2021 |
316 |
| 17 |
Reduction of observer variation using matched CT-PET for lung cancer delineation: A three-dimensional analysis
Roel J.H.M. Steenbakkers, Joop C. Duppen, Isabelle Fitton et al. · International Journal of Radiation Oncology*Biology*Physics
|
29 Sep 2005 |
309 |
| 18 |
Internal mammary and medial supraclavicular lymph node chain irradiation in stage I–III breast cancer (EORTC 22922/10925): 15-year results of a randomised, phase 3 trial
Philip M. Poortmans et al. · The Lancet Oncology
Open access |
2 Nov 2020 |
302 |
| 19 |
Single versus multiple fractions of repeat radiation for painful bone metastases: a randomised, controlled, non-inferiority trial
Edward Chow, Yvette M. van der Linden, Daniel E. Roos et al. · The Lancet Oncology
Open access |
22 Dec 2013 |
299 |
| 20 |
Ten-year results of the PORTEC-2 trial for high-intermediate risk endometrial carcinoma: improving patient selection for adjuvant therapy
for the PORTEC Study Group, Bastiaan G. Wortman, Carien L. Creutzberg et al. · British Journal of Cancer
Open access |
Oct 2018 |
291 |
| 21 |
Radiotherapy for Management of Extremity Soft Tissue Sarcomas: Why, When, and Where?
Rick L. Haas, Thomas F. DeLaney, Brian P O'Sullivan et al. · International Journal of Radiation Oncology*Biology*Physics
|
19 Apr 2012 |
265 |
| 22 |
PORTEC-4a: international randomized trial of molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer
Anne Sophie V M van den Heerik et al. · International Journal of Gynecological Cancer
Open access |
12 Oct 2020 |
251 |
| 23 |
Long-Term Outcome and Quality of Life of Patients With Endometrial Carcinoma Treated With or Without Pelvic Radiotherapy in the Post Operative Radiation Therapy in Endometrial Carcinoma 1 (PORTEC-1) Trial
Remi A. Nout, Lonneke V. van de Poll‐Franse, Marnix L.M. Lybeert et al. · Journal of Clinical Oncology
Open access |
29 Mar 2011 |
245 |
| 24 |
The morbidity of treatment for patients with stage I endometrial cancer: results from a randomized trial
Carien L. Creutzberg, Wim L.J. van Putten, Peter C.M. Koper et al. · International Journal of Radiation Oncology*Biology*Physics
|
Dec 2001 |
194 |
| 25 |
Clinical neurological outcome and quality of life among patients with limited small-cell cancer treated with two different doses of prophylactic cranial irradiation in the intergroup phase III trial (PCI99-01, EORTC 22003-08004, RTOG 0212 and IFCT 99-01)
Cecile Le Pechoux, A. Laplanche, Corinne Faivre Finn et al. · Annals of Oncology
Open access |
8 Dec 2010 |
191 |
| 26 |
Clinically node negative breast cancer patients undergoing breast conserving therapy, sentinel lymph node procedure versus follow-up: a Dutch randomized controlled multicentre trial (BOOG 2013-08)
Lori M. van Roozendaal, Marissa L. G. Vane, Thijs van Dalen et al. · BMC Cancer
Open access |
Jul 2017 |
190 |
| 27 |
Hypofractionated versus conventionally fractionated radiotherapy for patients with prostate cancer (HYPRO): acute toxicity results from a randomised non-inferiority phase 3 trial
Shafak Aluwini, Floris J. Pos, Erik C. Schimmel et al. · The Lancet Oncology
Open access |
2 Feb 2015 |
186 |
| 28 |
Low-Dose Palliative Radiotherapy for Cutaneous B- and T-Cell Lymphomas
Karen J. Neelis, Erik C. Schimmel, Maarten H. Vermeer et al. · International Journal of Radiation Oncology*Biology*Physics
|
2 Oct 2008 |
174 |
| 29 |
Molecular-integrated risk profile to determine adjuvant radiotherapy in endometrial cancer: Evaluation of the pilot phase of the PORTEC-4a trial
Bastiaan G. Wortman, Tjalling Bosse, Remi A. Nout et al. · Gynecologic Oncology
Open access |
3 Aug 2018 |
172 |
| 30 |
Five-year quality of life of endometrial cancer patients treated in the randomised Post Operative Radiation Therapy in Endometrial Cancer (PORTEC-2) trial and comparison with norm data
Remi A. Nout, Hein Putter, Ina Maria Jurgenliemk-Schulz et al. · European Journal of Cancer
Open access |
14 Dec 2011 |
168 |
| 31 |
Observer variation in target volume delineation of lung cancer related to radiation oncologist–computer interaction: A ‘Big Brother’ evaluation
Roel J.H.M. Steenbakkers, Joop C. Duppen, Isabelle Fitton et al. · Radiotherapy and Oncology
|
27 Oct 2005 |
163 |
| 32 |
Results of a phase II pilot study of moderate dose radiotherapy for inoperable desmoid-type fibromatosis—an EORTC STBSG and ROG study (EORTC 62991–22998)
Ronald B. Keus, Remi A. Nout, Jean‐Yves Blay et al. · Annals of Oncology
Open access |
18 Jul 2013 |
138 |
| 33 |
Interpretable deep learning model to predict the molecular classification of endometrial cancer from haematoxylin and eosin-stained whole-slide images: a combined analysis of the PORTEC randomised trials and clinical cohorts
Sarah Fremond et al. · The Lancet Digital Health
Open access |
7 Dec 2022 |
136 |
| 34 |
Long-Term Impact of Endometrial Cancer Diagnosis and Treatment on Health-Related Quality of Life and Cancer Survivorship: Results From the Randomized PORTEC-2 Trial
Stephanie M. de Boer, Remi A. Nout, Ina Maria Jurgenliemk-Schulz et al. · International Journal of Radiation Oncology*Biology*Physics
Open access |
18 Aug 2015 |
126 |
| 35 |
Desmoid tumors: need for an individualized approach
Eelco de Bree, Ronald B. Keus, John Melissas et al. · Expert Review of Anticancer Therapy
|
Apr 2009 |
120 |
| 36 |
First results of triple‐modality treatment combining radiotherapy, chemotherapy, and hyperthermia for the treatment of patients with Stage IIB, III, and IVA cervical carcinoma
Anneke M. Westermann, Ellen Louise Jones, Baard‐Christian Schem et al. · Cancer
Open access |
20 Jun 2005 |
119 |
| 37 |
First experience with model-based selection of head and neck cancer patients for proton therapy
Makbule Tambaş, Roel J.H.M. Steenbakkers, Hans Paul van der Laan et al. · Radiotherapy and Oncology
Open access |
5 Aug 2020 |
112 |
| 38 |
Radiation doses and fractionation schedules in non-low-risk ductal carcinoma in situ in the breast (BIG 3–07/TROG 07.01): a randomised, factorial, multicentre, open-label, phase 3 study
Boon Hui Chua et al. · The Lancet
Open access |
Aug 2022 |
109 |
| 39 |
Randomized Phase III Study Comparing Neoadjuvant Chemotherapy Followed by Surgery Versus Chemoradiation in Stage IB2-IIB Cervical Cancer: EORTC-55994
Gemma G. Kenter et al. · Journal of Clinical Oncology
Open access |
Sep 2023 |
106 |
| 40 |
Tumor volume as prognostic factor in chemoradiation for advanced head and neck cancer
J. Knegjens, Michael Hauptmann, Frank A. Pameijer et al. · Head & Neck
|
13 Jul 2010 |
103 |
| 41 |
Molecular Classification Predicts Response to Radiotherapy in the Randomized PORTEC-1 and PORTEC-2 Trials for Early-Stage Endometrioid Endometrial Cancer
Nanda Horeweg et al. · Journal of Clinical Oncology
Open access |
24 Jul 2023 |
101 |
| 42 |
Perspectives, fears and expectations of patients with gynaecological cancers during the COVID‐19 pandemic: A Pan‐European study of the European Network of Gynaecological Cancer Advocacy Groups (ENGAGe)
Murat Gültekin et al. · Cancer Medicine
Open access |
18 Nov 2020 |
101 |
| 43 |
Acute toxicity of curative radiotherapy for intermediate- and high-risk localised prostate cancer in the EORTC trial 22991
Oscar Matzinger, Frederic Duclos, A. van den Bergh et al. · European Journal of Cancer
|
13 Aug 2009 |
101 |
| 44 |
Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series ofin vitrobreast cancer models
Carol Ward, James R. Meehan, Peter Mullen et al. · Oncotarget
Open access |
3 Jul 2015 |
98 |
| 45 |
Engagement of I-Branching β-1, 6- N -Acetylglucosaminyltransferase 2 in Breast Cancer Metastasis and TGF-β Signaling
Haijun Zhang, Fanyan Meng, Sherwin Wu et al. · Cancer Research
Open access |
13 Jul 2011 |
95 |
| 46 |
Functional characterization of the 19q12 amplicon in grade III breast cancers
Rachael Natrajan, Alan G. Mackay, Paul M Wilkerson et al. · Breast Cancer Research
Open access |
20 Mar 2012 |
95 |
| 47 |
Shortened irradiation scheme, continuous infusion of 5-fluorouracil and fractionation of mitomycin C in locally advanced anal carcinomas. Results of a phase II study of the European Organization for Research and Treatment of Cancer. Radiotherapy and Gastrointestinal Cooperative Groups
Jean-François Bosset, Felicitas Roelofsen, David A.L. Morgan et al. · European Journal of Cancer
Open access |
28 Dec 2002 |
92 |
| 48 |
Prognostic Integrated Image-Based Immune and Molecular Profiling in Early-Stage Endometrial Cancer
Nanda Horeweg, Marco de Bruyn, Remi A. Nout et al. · Cancer Immunology Research
Open access |
30 Sep 2020 |
91 |
| 49 |
Ring Versus Ovoids and Intracavitary Versus Intracavitary-Interstitial Applicators in Cervical Cancer Brachytherapy: Results From the EMBRACE I Study
Monica F. Serban, Christian Kirisits, Astrid de Leeuw et al. · International Journal of Radiation Oncology*Biology*Physics
|
30 Jan 2020 |
90 |
| 50 |
Proteolytic Cleavage of Notch: “HIT and RUN”
Geert van Tetering, Marc Vooijs · Current Molecular Medicine
Open access |
Jun 2011 |
90 |