Science Explorer Back to mapMap

Most cited papers from Redx Pharma (United Kingdom)

What are the most cited papers from Redx Pharma (United Kingdom)?

The most cited paper from Redx Pharma (United Kingdom) is "Cross-validation pitfalls when selecting and assessing regression and classification models" (Damjan Krstajić, Ljubomir J. Buturović, David E. Leahy et al., 2014), with 1,115 citations. Next come "Standardization of test conditions for high performance liquid chromatography columns" (523) and "Immunohistochemical localisation of urogastrone to human duodenal and submandibular glands." (201).

Showing 50 of 69 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Cross-validation pitfalls when selecting and assessing regression and classification models Damjan Krstajić, Ljubomir J. Buturović, David E. Leahy et al. · Journal of Cheminformatics Open access 29 Mar 2014 1,115
2 Standardization of test conditions for high performance liquid chromatography columns Paul A. Bristow, John Henderson Knox · Chromatographia Jun 1977 523
3 Immunohistochemical localisation of urogastrone to human duodenal and submandibular glands. Philipp U. Heitz, M. Kasper, Susan Van Noorden et al. · Gut Open access May 1978 201
4 Further characterization of the covalent linking reaction of α2-macroglobulin Guy S. Salvesen, C A Sayers, A. John Barrett · Biochemical Journal Open access May 1981 195
5 Oxidative Stress and Assisted Reproduction: A Comprehensive Review of Its Pathophysiological Role and Strategies for Optimizing Embryo Culture Environment Ashok Kumar Agarwal, Israel Maldonado Rosas, Christina Anagnostopoulou et al. · Antioxidants Open access 28 Feb 2022 143
6 Inhibition of Bruton's TK regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation Gareth S. D. Purvis, Massimo Collino, Haidée Aranda-Tavío et al. · British Journal of Pharmacology Open access Jul 2020 73
7 Impairment of Atg5-Dependent Autophagic Flux Promotes Paraquat- and MPP+-Induced Apoptosis But Not Rotenone or 6-Hydroxydopamine Toxicity Aracely García‐García, Annandurai Anandhan, Michaela Burns et al. · Toxicological Sciences Open access 31 Aug 2013 68
8 Role of Lymph Nodes in Adjuvant-Induced Arthritis in Rats B. B. Newbould · Annals of the Rheumatic Diseases Open access Sep 1964 64
9 Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability Iryna Bohovych, Mario R. Fernandez, Jennifer J. Rahn et al. · Scientific Reports Open access 14 Sep 2015 60
10 Electron transfer amongst flavo- and hemo-proteins: diffusible species effect the relay processes, not protein–protein binding Kelath Murali Manoj, Sudeep Kumar Gade, Avanthika Venkatachalam et al. · RSC Advances 2016 59
11 Tumours of the Liver and Kidney Induced in Wistar Rats with 4′-Fluoro-4-Aminodiphenyl JOYCE J. MATTHEWS, Arthur L. Walpole · British Journal of Cancer Open access Jun 1958 52
12 Novel Bacterial Topoisomerase Inhibitors with Potent Broad-Spectrum Activity against Drug-Resistant Bacteria Cédric Charrier, Anne‐Marie Salisbury, Victoria J. Savage et al. · Antimicrobial Agents and Chemotherapy Open access 22 Feb 2017 45
13 The Wnt Pathway Inhibitor RXC004 Blocks Tumor Growth and Reverses Immune Evasion in Wnt Ligand–dependent Cancer Models Caroline Phillips, Inder Bhamra, Catherine Eagle et al. · Cancer Research Communications Open access 11 Aug 2022 37
14 Targeting ligand-dependent wnt pathway dysregulation in gastrointestinal cancers through porcupine inhibition Dustin James Flanagan, Simon A. Woodcock, Caroline Phillips et al. · Pharmacology & Therapeutics Open access 28 Mar 2022 37
15 Protection of Mice by Interferon Against Systemic Virus Infections Norman B. Finter · BMJ Open access 17 Oct 1964 33
16 Biological profiling of novel tricyclic inhibitors of bacterial DNA gyrase and topoisomerase IV Victoria J. Savage, Cédric Charrier, Anne‐Marie Salisbury et al. · Journal of Antimicrobial Chemotherapy 30 Mar 2016 28
17 Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase Sara R. Henderson, C.E.M. Stevenson, Brandon F. Malone et al. · Journal of Antimicrobial Chemotherapy Open access 13 Jun 2020 27
18 Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation Graham F. Smith et al. · Bioorganic & Medicinal Chemistry Letters Open access 17 Apr 2017 26
19 Estimation of Airborne Rat-Derived Antigens by ELISA Graham E. Davies, A Thompson, M. Rackham · Journal of Immunoassay 1983 26
20 Design, synthesis and antibacterial properties of pyrimido[4,5-b]indol-8-amine inhibitors of DNA gyrase David McGarry, Ian R. Cooper, Rolf Walker et al. · Bioorganic & Medicinal Chemistry Letters Open access 26 May 2018 18
21 Conformation Partition and Drug Design Robin H. Davies, Brian Sheard, Peter J. Taylor · Journal of Pharmaceutical Sciences Mar 1979 17
22 Discovery and structure–activity relationships of a novel oxazolidinone class of bacterial type II topoisomerase inhibitors Amanda J. Lyons et al. · Bioorganic & Medicinal Chemistry Letters Open access 26 Feb 2022 15
23 Identification of compounds acting as negative allosteric modulators of the LPA1 receptor Jonathan M. Ellery, Louise Dickson, Toni Cheung et al. · European Journal of Pharmacology Open access 26 May 2018 15
24 Inclusion of cancer-associated fibroblasts in drug screening assays to evaluate pancreatic cancer resistance to therapeutic drugs Sarah Brumskill, Lawrence N. Barrera, Peter J. Calcraft et al. · Journal of Physiology and Biochemistry Open access 5 Dec 2021 14
25 Whole body physiologically based modelling of β‐blockers in the rat: events in tissues and plasma following an i.v. bolus dose S.Y. Amy Cheung, Trudy Rodgers, Leon J Aarons et al. · British Journal of Pharmacology Open access 20 Oct 2017 14
26 The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses Rosie May Walker, Michael Chong, Nicolas Perrot et al. · Translational Psychiatry Open access 18 May 2024 13
27 Studies on the metabolism of the protozoa. The molecular structure of the reserve polysaccharide from Astasia ocellata DJ Manners, J. F. Ryley, J. Roger Stark · Biochemical Journal Open access Nov 1966 13
28 MRI texture analysis of T2-weighted images is preferred over magnetization transfer imaging for readily longitudinal quantification of gut fibrosis Isabelle De Kock, Simon Bos, Louke J. Delrue et al. · European Radiology Open access 18 Apr 2023 11
29 Discovery and structure–activity relationships of a novel isothiazolone class of bacterial type II topoisomerase inhibitors Ian R. Cooper et al. · Bioorganic & Medicinal Chemistry Letters Open access 29 Jul 2016 11
30 517MO Phase I study of the porcupine (PORCN) inhibitor RXC004 in patients with advanced solid tumours Natalie Cook, Sarah Patricia Blagden, Juanita Suzanne Lopez et al. · Annals of Oncology Open access Sep 2021 10
31 Efficacy of a Novel Tricyclic Topoisomerase Inhibitor in a Murine Model of Neisseria gonorrhoeae Infection Victoria J. Savage, Cédric Charrier, Anne‐Marie Salisbury et al. · Antimicrobial Agents and Chemotherapy Open access 22 Jun 2016 10
32 Adhesion G protein-coupled receptors Tobias Langenhan et al. · Pharmacological Reviews Open access 16 Jan 2026 9
33 New approach methodologies (NAMs) in drug safety assessment: A vision of the future Ruth Angela Roberts · Current Opinion in Toxicology 4 Sep 2024 9
34 Differential expression of cyclin-dependent kinases in the adult human retina in relation to CDK inhibitor retinotoxicity Phillip Wright, Janet Kelsall, Guy Healing et al. · Archives of Toxicology Open access 8 Jan 2019 9
35 In vitrobiological evaluation of novel broad-spectrum isothiazolone inhibitors of bacterial type II topoisomerases Cédric Charrier, Anne‐Marie Salisbury, Victoria J. Savage et al. · Journal of Antimicrobial Chemotherapy 26 Jun 2016 9
36 Analysis of β-catenin gene mutations and gene expression in liver tumours of C57BL/10J mice produced by chronic administration of sodium phenobarbital James E. Sidaway, Terry C. Orton, Kassiani Kalaitzi et al. · Toxicology 10 Dec 2019 8
37 A Conceptual Framework for Building Robust Data Governance and Quality Assurance Models in Multi-Cloud Analytics Ecosystems Jeffrey Chidera Ogeawuchi, Olanrewaju Oluwaseun Ajayi, Andrew Ifesinachi Daraojimba et al. · International Journal of Advanced Multidisciplinary Research and Studies Open access 31 Dec 2023 7
38 37P Phase II results of the porcupine (PORCN) inhibitor zamaporvint (RXC004) in genetically selected microsatellite stable colorectal cancer patients Natalie Cook, J.A. Bridgewater, Mark P. Saunders et al. · Annals of Oncology Open access Jun 2024 7
39 Rho-associated protein kinase 1 inhibition in hepatocytes attenuates nonalcoholic steatohepatitis Ester Dohnálková, Rachel L. Bayer, Qianqian Guo et al. · Hepatology Communications Open access Jun 2023 6
40 Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 1 Ralph Kirk et al. · RSC Medicinal Chemistry Open access 2020 5
41 Interplay between age, APOE Ɛ4 and the metabolome in plasma and brain in Alzheimer’s disease Najaf Amin, Jun Liu, William Sproviero et al. · Translational Psychiatry Open access 31 Oct 2025 4
42 REDX08608, a Novel, Potent and Selective, Reversible BTK Inhibitor with Efficacy and Equivalent Potency Against Wild-Type and Mutant C481S BTK Nicolas E. S. Guisot et al. · Blood 2 Dec 2016 4
43 WHAT IS A β-BLOCKER? J.D. Fitzgerald, A. M. Barrett · The Lancet Sep 1967 4
44 Safety considerations for cereblon-recruiting targeted protein degraders Helen Garside et al. · Nature Reviews Drug Discovery Review 20 Apr 2026 3
45 Inhibition of Bruton’s tyrosine kinase reduces NF-kB and NLRP3 inflammasome activity preventing insulin resistance and microvascular disease Gareth S. D. Purvis, Massimo Collino, Haidee M. A. Tavio et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 28 Aug 2019 3
46 On the utility of coupling polarised light microscopy to a solubility assay in drug discovery Philip A. MacFaul, Andrew J. Ratcliffe, Matute Tamara et al. · MedChemComm 2016 3
47 Application of A Tiered Approach to The Validation of Accelerator MS Assays David M. Higton, Mark Seymour · Bioanalysis Mar 2014 3
48 Synthesis of 3-Diethylamino-1-ethylisothiazolo[3,4-b]pyridinium Perchlorate and an Improved Route to 3-Azaisatoic Anhydride D. Le Count, D. J. DEWSBURY · Synthesis 15 May 2002 3
49 Novel N-thiazolyl piperazine-1-carboxamide CCR2 antagonists – investigation of an unexpected reaction with glutathione John G. Cumming, Philip A. MacFaul, Andrew G. Leach · MedChemComm 2015 3
50 391P Phase II results of the porcupine (PORCN) inhibitor zamaporvint (RXC004) in patients with pancreatic and biliary tract cancer J.A. Bridgewater, L. Chantrill, R. Gillmore et al. · Annals of Oncology Open access Jun 2024 2

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.