Most cited papers from Regeneron (United States)

Regeneron (United States)

What are the most cited papers from Regeneron (United States)?

The most cited paper from Regeneron (United States) is "Vascular-specific growth factors and blood vessel formation" (George D. Yancopoulos, Samuel H. Davis, Nicholas W. Gale et al., 2000), with 3,706 citations. Next come "Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome" (3,654) and "Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis" (3,588).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 59 papers. Every paper with more than 967 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Vascular-specific growth factors and blood vessel formation George D. Yancopoulos, Samuel H. Davis, Nicholas W. Gale et al. · Nature	Sep 2000	3,706
2	Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome Gregory G. Schwartz et al. · New England Journal of Medicine Open access	7 Nov 2018	3,654
3	Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis Peter C. Maisonpierre, Chitra Suri, Pamela F. Jones et al. · Science	4 Jul 1997	3,588
4	Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy Sue C. Bodine, Esther Latres, Susanne Baumhueter et al. · Science Open access	23 Nov 2001	3,550
5	The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function Jesse M. Cedarbaum, Nancy Stambler, Errol Malta et al. · Journal of the Neurological Sciences	Oct 1999	3,349
6	Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis Chitra Suri, Pamela F. Jones, Sybill Patan et al. · Cell Open access	Dec 1996	2,867
7	Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo Sue C. Bodine, Trevor N. Stitt, Michael Gonzalez et al. · Nature Cell Biology	10 Oct 2001	2,769
8	Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration Jeffrey S. Heier, David M. Brown, Victor N. Chong et al. · Ophthalmology	17 Oct 2012	2,522
9	Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events Jennifer G. Robinson, Michel Farnier, Michel Krempf et al. · New England Journal of Medicine Open access	15 Mar 2015	2,316
10	Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF Jocelyn A. Holash, Peter C. Maisonpierre, Debra L. Compton et al. · Science	18 Jun 1999	2,209
11	Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis Eric Lawrence Simpson et al. · New England Journal of Medicine Open access	Oct 2016	2,101
12	COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses Uğur Şahin et al. · Nature Open access	30 Sep 2020	2,072
13	Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning Samuel H. Davis, Thomas H. Aldrich, Pamela F. Jones et al. · Cell Open access	Dec 1996	1,998
14	The IGF-1/PI3K/Akt Pathway Prevents Expression of Muscle Atrophy-Induced Ubiquitin Ligases by Inhibiting FOXO Transcription Factors Trevor N. Stitt, Doreen Drujan, Brian A. Clarke et al. · Molecular Cell Open access	May 2004	1,972
15	ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF Teri G. Boulton, Steven H. Nye, David J. Robbins et al. · Cell	May 1991	1,921
16	Recognition of single-stranded RNA viruses by Toll-like receptor 7 Jennifer M. Lund, Lena Alexopoulou, Ayuko Sato et al. · Proceedings of the National Academy of Sciences Open access	19 Mar 2004	1,870
17	REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19 David M. Weinreich et al. · New England Journal of Medicine Open access	17 Dec 2020	1,806
18	CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis Julian David Gillmore et al. · New England Journal of Medicine Open access	26 Jun 2021	1,751
19	Plasma proteomic associations with genetics and health in the UK Biobank Benjamin B. Sun et al. · Nature Open access	4 Oct 2023	1,716
20	VEGF-Trap: A VEGF blocker with potent antitumor effects Jocelyn A. Holash, Sam Davis, Nick Papadopoulos et al. · Proceedings of the National Academy of Sciences Open access	12 Aug 2002	1,694
21	Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6 Raúl Mostoslavsky et al. · Cell Open access	2006	1,649
22	Computationally efficient whole-genome regression for quantitative and binary traits Joelle S. Mbatchou, Leland Barnard, Joshua Backman et al. · Nature Genetics	20 May 2021	1,637
23	Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways Christian Rommel, Sue C. Bodine, Brian A. Clarke et al. · Nature Cell Biology	5 Oct 2001	1,587
24	Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials Claus Bachert et al. · The Lancet	19 Sep 2019	1,564
25	BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra Carolyn Hyman, Magdalena Hofer, Yves‐Alain Barde et al. · Nature	Mar 1991	1,521
26	Regulation of the Germinal Center Response by MicroRNA-155 To‐Ha Thai, Dinis Pedro Calado, Stefano S Casola et al. · Science	26 Apr 2007	1,486
27	Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies Alina Baum, Benjamin O. Fulton, Elzbieta H Wloga et al. · Science Open access	15 Jun 2020	1,484
28	Molecular cloning and expression of brain-derived neurotrophic factor Joachim Leibrock, Friedrich Lottspeich, Andreas Höhn et al. · Nature	Sep 1989	1,474
29	Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system Hellmut G. Augustin, Gou Young Koh, Gavin Thurston et al. · Nature Reviews Molecular Cell Biology Review	23 Feb 2009	1,468
30	Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair Jeremy S. Duffield, Stuart John Forbes, Christothea M. Constandinou et al. · Journal of Clinical Investigation Open access	3 Jan 2005	1,448
31	Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail Johanna K. Hansen et al. · Science Open access	15 Jun 2020	1,436
32	PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma Michael Robert Migden et al. · New England Journal of Medicine Open access	4 Jun 2018	1,430
33	Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis Lisa A. Beck, Diamant Thaçi, Jennifer D. Hamilton et al. · New England Journal of Medicine	9 Jul 2014	1,426
34	Leakage-Resistant Blood Vessels in Mice Transgenically Overexpressing Angiopoietin-1 Gavin Thurston, Chitra Suri, Kenneth J. Smith et al. · Science	24 Dec 1999	1,369
35	IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice Dongsheng Cai, J. Daniel Frantz, Nicholas E. Tawa et al. · Cell Open access	Oct 2004	1,369
36	Dupilumab in Persistent Asthma with Elevated Eosinophil Levels Sally E. Wenzel, Linda Ford, David S. Pearlman et al. · New England Journal of Medicine Open access	21 May 2013	1,329
37	Angiopoietin-1 protects the adult vasculature against plasma leakage Gavin Thurston, John S. Rudge, Ella Ioffe et al. · Nature Medicine	Apr 2000	1,310
38	Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial Andrew Blauvelt et al. · The Lancet Open access	4 May 2017	1,269
39	Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF Peter C. Maisonpierre, Leonardo Belluscio, Stephen P. Squinto et al. · Science	23 Mar 1990	1,255
40	NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression Peter C. Maisonpierre, Leonardo Belluscio, Beth Friedman et al. · Neuron	Oct 1990	1,242
41	Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation David B. Lombard, Frederick W. Alt, Hwei-Ling Cheng et al. · Molecular and Cellular Biology Open access	9 Oct 2007	1,227
42	SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells Marcia C. Haigis, Raúl Mostoslavsky, Kevin M. Haigis et al. · Cell Open access	Sep 2006	1,162
43	Mapping the human genetic architecture of COVID-19 COVID-19 Host Genetics Initiative et al. · Nature Open access3,896 authors	8 Jul 2021	1,130
44	Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant Leonid Yurkovetskiy et al. · Cell Open access	15 Sep 2020	1,122
45	Skeletal muscle hypertrophy and atrophy signaling pathways David J. Glass · The International Journal of Biochemistry & Cell Biology	Jun 2005	1,105
46	The power of genetic diversity in genome-wide association studies of lipids Sarah E. Graham et al. · Nature Open access527 authors	9 Dec 2021	1,099
47	Exome sequencing and analysis of 454,787 UK Biobank participants Joshua Backman et al. · Nature Open access	18 Oct 2021	1,092
48	X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor Alexander I. Sobolevsky, Michael P. Rosconi, Eric Gouaux · Nature Open access	29 Nov 2009	1,051
49	Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab Nicholas J. Papadopoulos, Joel H. Martin, Qin Ruan et al. · Angiogenesis Open access	3 Feb 2012	1,048
50	Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis Ralf H. Adams, George A. Wilkinson, Chana Weiss et al. · Genes & Development Open access	Feb 1999	1,039

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.