Institution · Repligen (United States)
Most cited papers from Repligen (United States)
What are the most cited papers from Repligen (United States)?
The most cited paper from Repligen (United States) is "Cloning of B7-2: a CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation" (Gordon James Freeman, John G. Gribben, Vassiliki A. Boussiotis et al., 1993), with 920 citations. Next come "Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides" (708) and "Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant" (655).
Showing 50 of 60 papers. Every paper with more than 122 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Cloning of B7-2: a CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation Gordon James Freeman, John G. Gribben, Vassiliki A. Boussiotis et al. · Science | 5 Nov 1993 | 920 |
| 2 | Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides Theodore E. Maione, Gary S. Gray, Joan Petro et al. · Science | 5 Jan 1990 | 708 |
| 3 | Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant Gregory J. LaRosa, Joseph P. Davide, Kent J. Weinhold et al. · Science | 24 Aug 1990 | 655 |
| 4 | Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120. J R Rusche, Kashi Javaherian, Charlene B. McDanal et al. · Proceedings of the National Academy of Sciences | May 1988 | 624 |
| 5 | Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein. Kashi Javaherian, A J Langlois, Charlene B. McDanal et al. · Proceedings of the National Academy of Sciences | Sep 1989 | 620 |
| 6 | Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis Scott L. Gottlieb, Patricia Gilleaudeau, Ray A. Johnson et al. · Nature Medicine | May 1995 | 616 |
| 7 | Validation of the general purpose QUANTA ®3.2/CHARMm® force field Frank A. Momany, Rebecca J. Rone · Journal of Computational Chemistry | Sep 1992 | 581 |
| 8 | B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4 Gordon James Freeman, Vassiliki A. Boussiotis, Anukanth Anumanthan et al. · Immunity | May 1995 | 566 |
| 9 | HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation Susan C. McQuown, Ruth M. Barrett, Dina P. Matheos et al. · Journal of Neuroscience | 12 Jan 2011 | 514 |
| 10 | Production of multiple ligninases by Phanerochaete chrysosporium: effect of selected growth conditions and use of a mutant strain T. Kent Kirk, Suki C. Croan, Ming Tien et al. · Enzyme and Microbial Technology | 1986 | 504 |
| 11 | CERTS Microgrid Laboratory Test Bed Robert H. Lasseter, Joseph H. Eto, Benjamin L. Schenkman et al. · IEEE Transactions on Power Delivery | 29 Dec 2010 | 477 |
| 12 | Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs Hidemi Takahashi, Toshiyuki Takeshfta, Brør Morein et al. · Nature | 26 Apr 1990 | 476 |
| 13 | Prevention of HIV-1 infection in chimpanzees by gpl20 V3 domain-specific monoclonal antibody Emilio A. Emini, William A. Schleif, Jack H. Nunberg et al. · Nature | Feb 1992 | 476 |
| 14 | HIV-1 structural gene expression requires binding of the rev trans-activator to its RNA target sequence Michael H. Malim, Laurence S. Tiley, David F. McCarn et al. · Cell | Feb 1990 | 444 |
| 15 | Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma Assaf Magen et al. · Nature Medicine | Jun 2023 | 429 |
| 16 | HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner Melissa Malvaez, Susan C. McQuown, George A. Rogge et al. · Proceedings of the National Academy of Sciences | 7 Jan 2013 | 416 |
| 17 | A Formalin-Inactivated Whole SIV Vaccine Confers Protection in Macaques Michael Murphey‐Corb, Louis N. Martin, B. Davison‐Fairburn et al. · Science | 8 Dec 1989 | 407 |
| 18 | G protein-coupled signal transduction pathways for interleukin-8 Ding Wen Wu, G J LaRosa, Melvin I. Simon · Science | 2 Jul 1993 | 384 |
| 19 | Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro Thomas J. Daly, Kathleen Sue Cook, Gary S. Gray et al. · Nature | Dec 1989 | 382 |
| 20 | Absence of B7-dependent responses in CD28-deficient mice Jonathan M. Green, Patricia J. Noel, Anne I. Sperling et al. · Immunity | Sep 1994 | 382 |
| 21 | Multiple biological activities of human recombinant interleukin 1. Charles Anthony Dinarello, Joseph G. Cannon, J W Mier et al. · Journal of Clinical Investigation | Jun 1986 | 369 |
| 22 | Uncovering of Functional Alternative CTLA-4 Counter-Receptor in B7-Deficient Mice Gordon James Freeman, Frank Borriello, Richard J. Hodes et al. · Science | 5 Nov 1993 | 366 |
| 23 | Broadly Neutralizing Antibodies Elicited by the Hypervariable Neutralizing Determinant of HIV-1 Kashi Javaherian, A J Langlois, Greg J. LaRosa et al. · Science | 14 Dec 1990 | 351 |
| 24 | Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7. Gordon James Freeman, G S Gray, Claude D. Gimmi et al. · The Journal of Experimental Medicine | Sep 1991 | 347 |
| 25 | HTLV-III/LAV-Neutralizing Antibodies to an E. coli -Produced Fragment of the Virus Envelope Scott D. Putney, Thomas J. Matthews, W. Gerard Robey et al. · Science | 12 Dec 1986 | 332 |
| 26 | CTLA4 mediates antigen-specific apoptosis of human T cells. John G. Gribben, Gordon James Freeman, Vassiliki A. Boussiotis et al. · Proceedings of the National Academy of Sciences | 31 Jan 1995 | 326 |
| 27 | Characterization of CTLA-4 structure and expression on human T cells. Tullia Lindsten, K P Lee, Estelle S. Harris et al. · The Journal of Immunology | Oct 1993 | 323 |
| 28 | Differential up-regulation of the B7-1 and B7-2 costimulatory molecules after Ig receptor engagement by antigen. Deborah J. Lenschow, Anne I. Sperling, Michael P. Cooke et al. · The Journal of Immunology | Sep 1994 | 292 |
| 29 | Defining the Interleukin-8-binding Domain of Heparan Sulfate Dorothe Spillmann, Dan Witt, Ulf Lindahl · Journal of Biological Chemistry | Jun 1998 | 269 |
| 30 | Clinical and Biological Subtypes of B-cell Lymphoma Revealed by Microenvironmental Signatures Nikita Kotlov et al. · Cancer Discovery | 4 Feb 2021 | 266 |
| 31 | C5L2, a Nonsignaling C5A Binding Protein Shoji Okinaga, Dubhfeasa Slattery, Alison A. Humbles et al. · Biochemistry | 15 Jul 2003 | 263 |
| 32 | A Leucine Zipper Stabilizes the Pentameric Membrane Domain of Phospholamban and Forms a Coiled-coil Pore Structure Heather K.B. Simmerman, Yvonne Monique Kobayashi, Joseph M. Autry et al. · Journal of Biological Chemistry | Mar 1996 | 257 |
| 33 | Interleukin-8 gene induction in the myocardium after ischemia and reperfusion in vivo. Gilbert L. Kukielka, C. Wayne Smith, G J LaRosa et al. · Journal of Clinical Investigation | 1995 | 246 |
| 34 | Crystal Structure of the Principal Neutralization Site of HIV-1 Jayant B. Ghiara, Enrico Adriano Stura, Robyn L. Stanfield et al. · Science | Apr 1994 | 242 |
| 35 | Anti‐CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat H. Chen, Michael Chopp, R. L. Zhang et al. · Annals of Neurology | Apr 1994 | 230 |
| 36 | Physical and enzymatic properties of lignin peroxidase isoenzymes from Phanerochaete chrysosporium Roberta L. Farrell, Karen E. Murtagh, Ming Tien et al. · Enzyme and Microbial Technology | Jun 1989 | 215 |
| 37 | Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans Salman R. Khetani, Chitra Kanchagar, Okechukwu T. Ukairo et al. · Toxicological Sciences | 14 Nov 2012 | 211 |
| 38 | Major antigen-induced domain rearrangements in an antibody Robyn L. Stanfield, Midori Takimoto‐Kamimura, James M. Rini et al. · Structure | Oct 1993 | 209 |
| 39 | Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation. Vassiliki A. Boussiotis, Gordon James Freeman, JG Gribben et al. · Proceedings of the National Academy of Sciences | Dec 1993 | 206 |
| 40 | Platelet Factor-4 Inhibits the Mitogenic Activity of VEGF121 and VEGF165 Using Several Concurrent Mechanisms Stela Gengrinovitch, Sheryl M. Greenberg, Tzafra Cohen et al. · Journal of Biological Chemistry | Jun 1995 | 200 |
| 41 | Distinct roles for B7-1 (CD-80) and B7-2 (CD-86) in the initiation of experimental allergic encephalomyelitis. Michael K. Racke, Dorothy E. Scott, Laura Quigley et al. · Journal of Clinical Investigation | Nov 1995 | 192 |
| 42 | Growth Inhibition of Murine Melanoma and Human Colon Carcinoma by Recombinant Human Platelet Factor 4 Richard J. Sharpe, H. Randolph Byers, Charles F. Scott et al. · JNCI Journal of the National Cancer Institute | 16 May 1990 | 192 |
| 43 | A Single Amino Acid Interchange Yields Reciprocal CTL Specificities for HIV-1 gp160 Hidemi Takahashi, Silvia Merli, Scott D. Putney et al. · Science | 6 Oct 1989 | 178 |
| 44 | Amino terminus of the interleukin-8 receptor is a major determinant of receptor subtype specificity. G J LaRosa, Kaden M. Thomas, Maren Kaufmann et al. · Journal of Biological Chemistry | Dec 1992 | 175 |
| 45 | Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease Haiqun Jia, Judit Pallos, Vincent Jacques et al. · Neurobiology of Disease | 12 Feb 2012 | 166 |
| 46 | INHIBITION OF TRANSPLANT REJECTION FOLLOWING TREATMENT WITH ANTI-B7-2 AND ANTI-B7-1 ANTIBODIES Deborah J. Lenschow, Yijun Zeng, Karen S. Hathcock et al. · Transplantation | Nov 1995 | 162 |
| 47 | Epigenetic therapy for F riedreich ataxia Elisabetta Soragni et al. · Annals of Neurology | 27 Aug 2014 | 155 |
| 48 | Meeting the Challenge of Predicting Hepatic Clearance of Compounds Slowly Metabolized by Cytochrome P450 Using a Novel Hepatocyte Model, HepatoPac Tom S. Chan, Hongbin Yu, Amanda Moore et al. · Drug Metabolism and Disposition | 20 Aug 2013 | 151 |
| 49 | Role of B7:CD28/CTLA-4 in the induction of chronic relapsing experimental allergic encephalomyelitis. Peter James Perrin, Dorothy E. Scott, Laura Quigley et al. · The Journal of Immunology | Feb 1995 | 149 |
| 50 | Inhibition of tumor growth in mice by an analogue of platelet factor 4 that lacks affinity for heparin and retains potent angiostatic activity. T E Maione, G S Gray, Anthony J. Hunt et al. · PubMed | 15 Apr 1991 | 148 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.