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Most cited papers from Robert Koch Institute

What are the most cited papers from Robert Koch Institute?

The most cited paper from Robert Koch Institute is "SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor" (Markus Hoffmann, Hannah Kleine‐Weber, Simon Schroeder et al., 2020), with 21,493 citations. Next come "ResFinder 4.0 for predictions of phenotypes from genotypes" (3,475) and "Estimates of global seasonal influenza-associated respiratory mortality: a modelling study" (3,158).

Showing 50 of 60 papers. Every paper with more than 631 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Markus Hoffmann, Hannah Kleine‐Weber, Simon Schroeder et al. · Cell Open access 8 Mar 2020 21,493
2 ResFinder 4.0 for predictions of phenotypes from genotypes Valeria Bortolaia et al. · Journal of Antimicrobial Chemotherapy Open access 16 Jul 2020 3,475
3 Estimates of global seasonal influenza-associated respiratory mortality: a modelling study Angela Danielle Iuliano et al. · The Lancet Open access138 authors 13 Dec 2017 3,158
4 How long do nosocomial pathogens persist on inanimate surfaces? A systematic review Axel Krämer, Ingeborg Schwebke, Günter Kampf · BMC Infectious Diseases ReviewOpen access 16 Aug 2006 2,546
5 Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study Ting Shi et al. · The Lancet ReviewOpen access122 authors 7 Jul 2017 2,491
6 PCR inhibitors - occurrence, properties and removal Christina Schrader, Anika Schielke, Lüppo Ihno Ellerbroek et al. · Journal of Applied Microbiology 2 Jul 2012 2,194
7 CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells Volker Henn, Joseph R. Slupsky, Michael Gräfe et al. · Nature Feb 1998 2,088
8 Using Fourier transform IR spectroscopy to analyze biological materials Matthew J. Baker et al. · Nature Protocols Open access 3 Jul 2014 1,974
9 Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation Gero Hütter, Daniel R. Nowak, Maximilian Mossner et al. · New England Journal of Medicine Open access 11 Feb 2009 1,852
10 Guideline to reference gene selection for quantitative real-time PCR Aleksandar Radonić, Stefanie Thulke, Ian M Mackay et al. · Biochemical and Biophysical Research Communications 19 Dec 2003 1,664
11 COVID-19: towards controlling of a pandemic Juliet Bedford, Delia Alcira Enria, Johan Giesecke et al. · The Lancet Open access Mar 2020 1,649
12 Real-time, portable genome sequencing for Ebola surveillance Joshua C Quick et al. · Nature Open access102 authors Feb 2016 1,600
13 Typing of Methicillin-Resistant Staphylococcus aureus in a University Hospital Setting by Using Novel Software for spa Repeat Determination and Database Management Dag Harmsen, Heike Claus, Wolfgang Witte et al. · Journal of Clinical Microbiology Open access Dec 2003 1,588
14 Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19 Jenny Meinhardt et al. · Nature Neuroscience Open access 30 Nov 2020 1,511
15 ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28 Andreas Hutloff, Anna‐Maria Dittrich, Katja C. Beier et al. · Nature 1999 1,492
16 Vitamin D deficiency in Europe: pandemic? Kevin D. Cashman et al. · American Journal of Clinical Nutrition Open access 11 Feb 2016 1,401
17 SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19 Julian Braun et al. · Nature Open access 29 Jul 2020 1,400
18 Impact of sex and gender on COVID-19 outcomes in Europe Cathérine Gebhard, Vera Regitz‐Zagrosek, Hannelore K. Neuhauser et al. · Biology of Sex Differences Open access 25 May 2020 1,375
19 The Hidden Geometry of Complex, Network-Driven Contagion Phenomena Dirk Brockmann, Dirk Helbing · Science 12 Dec 2013 1,331
20 Salt-responsive gut commensal modulates TH17 axis and disease Nicola Wilck et al. · Nature Open access Nov 2017 1,326
21 Epidemiology of benign paroxysmal positional vertigo: a population based study M. von Brevern, Andrea Radtke, Franziska Lezius et al. · Journal of Neurology Neurosurgery & Psychiatry Open access 29 Nov 2006 1,255
22 Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage René S. Hendriksen et al. · Nature Communications Open access128 authors 8 Mar 2019 1,232
23 Candida albicans Secreted Aspartyl Proteinases in Virulence and Pathogenesis Julian R. Naglik, Stephen Challacombe, Bernhard Hube · Microbiology and Molecular Biology Reviews ReviewOpen access Sep 2003 1,186
24 Epidemic Profile of Shiga-Toxin–ProducingEscherichia coliO104:H4 Outbreak in Germany Christina Frank et al. · New England Journal of Medicine Open access 22 Jun 2011 1,143
25 Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution Jörg Hinrich Hacker, Gabriele Blum–Oehler, Inge Mühldorfer et al. · Molecular Microbiology Open access Mar 1997 1,140
26 Hypertension Treatment and Control in Five European Countries, Canada, and the United States Katharina Wolf-Maier, Richard Cooper, Holly Kramer et al. · Hypertension Open access 25 Nov 2003 1,086
27 Impact of the COVID-19 pandemic on quality of life and mental health in children and adolescents in Germany Ulrike Ravens‐Sieberer, Anne Kaman, Michael Erhart et al. · European Child & Adolescent Psychiatry Open access 25 Jan 2021 1,085
28 Tackling antibiotic resistance Karen Bush et al. · Nature Reviews Microbiology Open access 2 Nov 2011 1,077
29 The order Herpesvirales Andrew J. Davison, Richard L. Eberle, Bernhard Ehlers et al. · Archives of Virology Open access 8 Dec 2008 1,015
30 Critical Assessment of Metagenome Interpretation—a benchmark of metagenomics software Alexander Sczyrba et al. · Nature Methods Open access 2 Oct 2017 983
31 Effective containment explains subexponential growth in recent confirmed COVID-19 cases in China Benjamin F. Maier, Dirk Brockmann · Science Open access 8 Apr 2020 975
32 Burden of Six Healthcare-Associated Infections on European Population Health: Estimating Incidence-Based Disability-Adjusted Life Years through a Population Prevalence-Based Modelling Study Alessandro Cassini, Diamantis Plachouras, Tim Eckmanns et al. · PLoS Medicine Open access 18 Oct 2016 954
33 Medical Consequences of Antibiotic Use in Agriculture Wolfgang Witte · Science 13 Feb 1998 942
34 Swarm Learning for decentralized and confidential clinical machine learning Stefanie Warnat‐Herresthal et al. · Nature Open access181 authors 26 May 2021 896
35 Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study Christian Karagiannidis, Carina Mostert, Corinna Hentschker et al. · The Lancet Respiratory Medicine Open access 28 Jul 2020 867
36 Lessons learnt from easing COVID-19 restrictions: an analysis of countries and regions in Asia Pacific and Europe Emeline Kai Lin Han, Melisa Mei Jin Tan, Eva Turk et al. · The Lancet Open access 24 Sep 2020 859
37 KIDSCREEN-52 quality-of-life measure for children and adolescents Ulrike Ravens‐Sieberer, Angela Gosch, Luís Rajmil et al. · Expert Review of Pharmacoeconomics & Outcomes Research Jun 2005 837
38 Identification of medically relevant microorganisms by vibrational spectroscopy Kees Maquelin, C. Kirschner, Lin‐P'ing Choo‐Smith et al. · Journal of Microbiological Methods 8 Oct 2002 829
39 Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells Annabell Bachem, Steffen Güttler, Evelyn Hartung et al. · The Journal of Experimental Medicine Open access 17 May 2010 813
40 A very small porcine virus with circular single-stranded DNA Ilse Tischer, Hans A. J. Gelderblom, W. Vettermann et al. · Nature 1982 807
41 Towards tuberculosis elimination: an action framework for low-incidence countries Knut Lönnroth et al. · European Respiratory Journal Open access 18 Mar 2015 791
42 Prospective Genomic Characterization of the German Enterohemorrhagic Escherichia coli O104:H4 Outbreak by Rapid Next Generation Sequencing Technology Alexander Mellmann, Dag Harmsen, Craig A. Cummings et al. · PLoS ONE Open access 20 Jul 2011 775
43 Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study Martina Bielaszewska, Alexander Mellmann, Wenlan Zhang et al. · The Lancet Infectious Diseases Open access 25 Jun 2011 767
44 Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 Simon I Hay et al. · The Lancet Open access2,780 authors Oct 2025 762
45 Rising rural body-mass index is the main driver of the global obesity epidemic in adults Honor Bixby et al. · Nature Open access1,155 authors 8 May 2019 758
46 Psychische Störungen in der Allgemeinbevölkerung Frank Jacobi, Michael Höfler, Jens Strehle et al. · Der Nervenarzt 2014 746
47 Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency Bodo Grimbacher, Andreas Hutloff, Michael Schlesier et al. · Nature Immunology 10 Feb 2003 738
48 Risk Factors for Severe Outcomes following 2009 Influenza A (H1N1) Infection: A Global Pooled Analysis Maria D. Van Kerkhove et al. · PLoS Medicine Open access 5 Jul 2011 734
49 Escherichia coliHarboring Shiga Toxin 2 Gene Variants: Frequency and Association with Clinical Symptoms Alexander W. Friedrich, Martina Bielaszewska, Wenlan Zhang et al. · The Journal of Infectious Diseases 2002 727
50 German Outbreak of Escherichia coli O104:H4 Associated with Sprouts Udo Buchholz et al. · New England Journal of Medicine Open access 26 Oct 2011 722

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.