| 1 |
Should We STOP Angiotensin Converting Enzyme Inhibitors/Angiotensin Receptor Blockers in Advanced Kidney Disease?
Aimun Ahmed, Tom Jorna, Sunil Bhandari · The Nephron journals/Nephron journals
|
2016 |
11,736 |
| 2 |
Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial
Nicholas David James et al. · The Lancet
Open access |
21 Dec 2015 |
1,985 |
| 3 |
Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy
Nicholas David James et al. · New England Journal of Medicine
Open access |
3 Jun 2017 |
1,806 |
| 4 |
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
Ashley Harris Beecham et al. · Nature Genetics
Open access193 authors |
29 Sep 2013 |
1,466 |
| 5 |
Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial
David Paul Dearnaley et al. · The Lancet Oncology
Open access |
22 Jun 2016 |
1,350 |
| 6 |
Prognostic factors in ALS: A critical review
Adriano Chiò, Giancarlo Logroscino, Orla M. Hardiman et al. · Amyotrophic Lateral Sclerosis
Open access |
2009 |
1,184 |
| 7 |
Mapping the human genetic architecture of COVID-19
COVID-19 Host Genetics Initiative et al. · Nature
Open access3,896 authors |
8 Jul 2021 |
1,130 |
| 8 |
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)
Robert G. Miller, John D. Mitchell, Dan H. Moore · Cochrane Database of Systematic Reviews
Open access |
9 Mar 2012 |
1,064 |
| 9 |
LOW-ANGLE FIXATION IN FRACTURES OF THE FEMORAL NECK
R. S. Garden · Journal of Bone and Joint Surgery - British Volume
|
Nov 1961 |
980 |
| 10 |
Unpublished rating scales: A major source of bias in randomised controlled trials of treatments for schizophrenia
Max J. Marshall, Austin Lockwood, Caroline E. Bradley et al. · The British Journal of Psychiatry
Open access |
Mar 2000 |
870 |
| 11 |
Multilocus Sequence Typing System for Campylobacter jejuni
Kate E. Dingle, Frances M. Colles, David R A Wareing et al. · Journal of Clinical Microbiology
Open access |
2001 |
863 |
| 12 |
Watch-and-wait approach versus surgical resection after chemoradiotherapy for patients with rectal cancer (the OnCoRe project): a propensity-score matched cohort analysis
Andrew G. Renehan, Lee Malcomson, Richard A Emsley et al. · The Lancet Oncology
|
18 Dec 2015 |
813 |
| 13 |
Incidence of amyotrophic lateral sclerosis in Europe
Giancarlo Logroscino, Bryan J Traynor, Orla M. Hardiman et al. · Journal of Neurology Neurosurgery & Psychiatry
Open access |
25 Aug 2009 |
771 |
| 14 |
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection
Yanick Joseph Crow et al. · Nature Genetics
|
16 Jul 2006 |
683 |
| 15 |
Characterization of human disease phenotypes associated with mutations in TREX1 , RNASEH2A , RNASEH2B , RNASEH2C , SAMHD1 , ADAR , and IFIH1
Yanick Joseph Crow et al. · American Journal of Medical Genetics Part A
Open access136 authors |
16 Jan 2015 |
617 |
| 16 |
Prophylactic vaccination against human papillomaviruses to prevent cervical cancer and its precursors
Marc Arbyn, Lan Xu, Cindy Simoens et al. · Cochrane Database of Systematic Reviews
Open access |
8 May 2018 |
612 |
| 17 |
Randomised controlled trial of efficacy of teaching patients with bipolar disorder to identify early symptoms of relapse and obtain treatment
Amy L. Perry, Nicholas Tarrier, Richard Keith Morriss et al. · BMJ
Open access |
16 Jan 1999 |
591 |
| 18 |
Amyotrophic lateral sclerosis
J D Mitchell, Gian Domenico Borasio · The Lancet
|
Jun 2007 |
568 |
| 19 |
Cytology versus HPV testing for cervical cancer screening in the general population
George Koliopoulos, Victoria Nyawira Nyaga, Nancy A. Santesso et al. · Cochrane Database of Systematic Reviews
Open access |
10 Aug 2017 |
505 |
| 20 |
Tracing the Source of Campylobacteriosis
Daniel J. Wilson, Edith Gabriel, A. J. H. Leatherbarrow et al. · PLoS Genetics
Open access |
25 Sep 2008 |
452 |
| 21 |
Descriptive epidemiology of amyotrophic lateral sclerosis: new evidence and unsolved issues
Giancarlo Logroscino, Bryan J. Traynor, Orla M. Hardiman et al. · Journal of Neurology Neurosurgery & Psychiatry
|
13 Dec 2007 |
448 |
| 22 |
Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study
Gillian Rice et al. · The Lancet Neurology
Open access |
30 Oct 2013 |
447 |
| 23 |
Incidence of Vestibular Schwannoma and Neurofibromatosis 2 in the North West of England over a 10-year Period: Higher Incidence than Previously Thought
D. Gareth Evans, Anthony Moran, Andrew Thomas King et al. · Otology & Neurotology
|
2005 |
424 |
| 24 |
Glucose transporter-1 deficiency syndrome: the expanding clinical and genetic spectrum of a treatable disorder
Willemijn G. Leen et al. · Brain
Open access |
2 Feb 2010 |
422 |
| 25 |
Surgery for cervical intraepithelial neoplasia
Pierre PL Martin-Hirsch, Evangelos A. Paraskevaidis, Andrew Bryant et al. · Cochrane Database of Systematic Reviews
Open access |
4 Dec 2013 |
408 |
| 26 |
Systematic Review and Individual Patient Data Meta-analysis of Randomized Trials Comparing a Single Immediate Instillation of Chemotherapy After Transurethral Resection with Transurethral Resection Alone in Patients with Stage pTa–pT1 Urothelial Carcinoma of the Bladder: Which Patients Benefit from the Instillation?
Richard J Sylvester, Willem Oosterlinck, Sten Holmäng et al. · European Urology
ReviewOpen access |
16 Jun 2015 |
393 |
| 27 |
Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol
Gerhardt Attard et al. · The Lancet
ReviewOpen access173 authors |
23 Dec 2021 |
387 |
| 28 |
ENDEMIC CHOLERA IN RURAL BANGLADESH, 1966–1980
Roger I. Glass, Stan Becker, M. I. Huq et al. · American Journal of Epidemiology
|
Dec 1982 |
361 |
| 29 |
Whole-genome sequencing reveals host factors underlying critical COVID-19
Athanasios Kousathanas et al. · Nature
Open access2,399 authors |
7 Mar 2022 |
356 |
| 30 |
Randomized Controlled Trial of Oral Antifungal Treatment for Severe Asthma with Fungal Sensitization
David W. Denning, B. Ronan O’Driscoll, Georgina Powell et al. · American Journal of Respiratory and Critical Care Medicine
Open access |
23 Oct 2008 |
345 |
| 31 |
MALREDUCTION AND AVASCULAR NECROSIS IN SUBCAPITAL FRACTURES OF THE FEMUR
R. S. Garden · Journal of Bone and Joint Surgery - British Volume
|
May 1971 |
343 |
| 32 |
A new method for active surveillance of adverse events from diphtheria/tetanus/pertussis and measles/mumps/rubella vaccines
Paddy Farrington, Marie C. Rush, Emma Ruth Miller et al. · The Lancet
Open access |
Mar 1995 |
339 |
| 33 |
Interventions targeted at women to encourage the uptake of cervical screening
Thomas R. Everett, Andrew Bryant, Michelle F. Griffin et al. · Cochrane Database of Systematic Reviews
Open access |
11 May 2011 |
338 |
| 34 |
STABILITY AND UNION IN SUBCAPITAL FRACTURES OF THE FEMUR
R. S. Garden · Journal of Bone and Joint Surgery - British Volume
|
Nov 1964 |
337 |
| 35 |
Campylobacter Contamination of Raw Meat and Poultry at Retail Sale: Identification of Multiple Types and Comparison with Isolates from Human Infection
John M. Kramer, Jennifer A. Frost, F. J. Bolton et al. · Journal of Food Protection
Open access |
Dec 2000 |
329 |
| 36 |
Prevalence and numbers of Salmonella and Campylobacter spp. on raw, whole chickens in relation to sampling methods
Frieda Jorgensen, Richard Anthony Bailey, Scott David Williams et al. · International Journal of Food Microbiology
|
Jun 2002 |
323 |
| 37 |
Hepatotoxicity of herbal remedies.
Fiona B. MacGregor, V. E. Abernethy, S. Dahabra et al. · BMJ
Open access |
4 Nov 1989 |
315 |
| 38 |
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
Heather Jane Cordell et al. · Nature Communications
Open access462 authors |
22 Sep 2015 |
313 |
| 39 |
Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol.
Attard, Gerhardt et al. · BORIS (University Library Bern)
ReviewOpen access |
29 Jan 2022 |
311 |
| 40 |
HIV infection and stroke: current perspectives and future directions
Laura A. Benjamin, Alan Bryer, Hedley C A Emsley et al. · The Lancet Neurology
Open access |
17 Sep 2012 |
311 |
| 41 |
Ten-Year Results of FAST: A Randomized Controlled Trial of 5-Fraction Whole-Breast Radiotherapy for Early Breast Cancer
Adrian Murray Brunt et al. · Journal of Clinical Oncology
Open access |
14 Jul 2020 |
310 |
| 42 |
The identification and management of interstitial lung disease in systemic sclerosis: evidence-based European consensus statements
Anna‐Maria Hoffmann‐Vold et al. · The Lancet Rheumatology
Open access |
14 Jan 2020 |
309 |
| 43 |
Obstetric outcomes after conservative treatment for cervical intraepithelial lesions and early invasive disease
Maria Kyrgiou, Antonios Athanasiou, Ilkka E. J. Kalliala et al. · Cochrane Database of Systematic Reviews
Open access |
2 Nov 2017 |
306 |
| 44 |
Vocational rehabilitation for people with severe mental illness
Ruth Crowther, Max J. Marshall, Gary R. Bond et al. · Cochrane Database of Systematic Reviews
Open access |
23 Apr 2001 |
294 |
| 45 |
The effect of a multicomponent multidisciplinary bundle of interventions on sleep and delirium in medical and surgical intensive care patients
Jankee Patel, Jacqueline Baldwin, Peter S. Bunting et al. · Anaesthesia
|
11 May 2014 |
288 |
| 46 |
A Self-Rating Scale for Measuring Neuroleptic Side-Effects
Jennifer Cheeseman Day, Graham Charles Wood, Mike Dewey et al. · The British Journal of Psychiatry
|
May 1995 |
287 |
| 47 |
Verotoxin producing Escherichia coli O 157 infections associated with the consumption of yoghurt
D R Morgan, C Newman, D. N. Hutchinson et al. · Epidemiology and Infection
Open access |
Oct 1993 |
270 |
| 48 |
Bariatric surgery and its impact on cardiovascular disease and mortality: A systematic review and meta-analysis
Chun Shing Kwok, Ashish Kumar Pradhan, Muhammad A Khan et al. · International Journal of Cardiology
ReviewOpen access |
24 Feb 2014 |
265 |
| 49 |
The Extended Deep Inferior Epigastric Flap
G. Ian Taylor, Russell J. Corlett, J. Brian Boyd · Plastic & Reconstructive Surgery
|
Dec 1983 |
263 |
| 50 |
Randomised, double-blind, placebo-controlled treatment trial of fluoxetine and graded exercise for chronic fatigue syndrome†
Alison J. Wearden, Richard Keith Morriss, Ricky Mullis et al. · The British Journal of Psychiatry
|
Jun 1998 |
254 |