Most cited papers from Saitama Cancer Center

Saitama Cancer Center

What are the most cited papers from Saitama Cancer Center?

The most cited paper from Saitama Cancer Center is "The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology" (N.K. Aaronson, Sam Hjelmeland Ahmedzai, Bengt Bergman et al., 1993), with 16,252 citations. Next come "Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer" (2,901) and "Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer" (2,660).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 60 papers. Every paper with more than 306 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology N.K. Aaronson, Sam Hjelmeland Ahmedzai, Bengt Bergman et al. · JNCI Journal of the National Cancer Institute	3 Mar 1993	16,252
2	Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer Matthew David Hellmann et al. · New England Journal of Medicine Open access	28 Sep 2019	2,901
3	Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer Fabrice André, Eva M. Ciruelos, Gábor Rubovszky et al. · New England Journal of Medicine Open access	15 May 2019	2,660
4	An improved algorithm for matching biological sequences Osamu Gotoh · Journal of Molecular Biology	Dec 1982	1,777
5	Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo-controlled, phase 3 study Jong‐Mu Sun et al. · The Lancet Open access	Aug 2021	1,679
6	First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial Luis G Paz-Ares et al. · The Lancet Oncology	18 Jan 2021	1,396
7	Substrate recognition sites in cytochrome P450 family 2 (CYP2) proteins inferred from comparative analyses of amino acid and coding nucleotide sequences. Osamu Gotoh · Journal of Biological Chemistry Open access	1992	1,208
8	Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population Kazue Imai, Satoru Matsuyama, Satoshi Miyaké et al. · The Lancet	Nov 2000	1,194
9	Adjuvant chemotherapy of S-1 versus gemcitabine for resected pancreatic cancer: a phase 3, open-label, randomised, non-inferiority trial (JASPAC 01) Katsuhiko Uesaka, Narikazu Boku, Akira Fukutomi et al. · The Lancet	3 Jun 2016	1,145
10	Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability–High/Mismatch Repair–Deficient Metastatic Colorectal Cancer: KEYNOTE-164 Dung Thi Le et al. · Journal of Clinical Oncology Open access	14 Nov 2019	1,038
11	The Effect of Abemaciclib Plus Fulvestrant on Overall Survival in Hormone Receptor–Positive, ERBB2-Negative Breast Cancer That Progressed on Endocrine Therapy—MONARCH 2 George W. Sledge, Masakazu Toi, Patrick Neven et al. · JAMA Oncology Open access	29 Sep 2019	1,016
12	Regorafenib Plus Nivolumab in Patients With Advanced Gastric or Colorectal Cancer: An Open-Label, Dose-Escalation, and Dose-Expansion Phase Ib Trial (REGONIVO, EPOC1603) Shota Fukuoka, Hiroki Hara, Naoki Takahashi et al. · Journal of Clinical Oncology	28 Apr 2020	947
13	t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1. Hiroyuki Miyoshi, K Shimizu, T Kozu et al. · Proceedings of the National Academy of Sciences Open access	Dec 1991	893
14	Tepotinib in Non–Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations Paul K. Paik et al. · New England Journal of Medicine Open access	28 May 2020	891
15	Genetic Polymorphisms in the 5′-Flanking Region Change Transcriptional Regulation of the Human Cytochrome P450IIE1 Gene1 Shin‐ichi Hayashi, Junko A. Watanabe, Kaname Kawajiri · The Journal of Biochemistry	Oct 1991	677
16	Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-squamous non-small-cell lung cancer (NEJ026): interim analysis of an open-label, randomised, multicentre, phase 3 trial Haruhiro Saito et al. · The Lancet Oncology Open access	8 Apr 2019	646
17	Alpelisib plus fulvestrant for PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor-2–negative advanced breast cancer: final overall survival results from SOLAR-1 Fabrice André, Eva Ciruelos, Dejan Juric et al. · Annals of Oncology Open access	24 Nov 2020	621
18	Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial Miguel Martín et al. · The Lancet Oncology 626 authors	13 Nov 2017	594
19	Fluorouracil versus combination of irinotecan plus cisplatin versus S-1 in metastatic gastric cancer: a randomised phase 3 study Narikazu Boku, Seiichiro Yamamoto, Haruhiko Fukuda et al. · The Lancet Oncology	9 Oct 2009	594
20	Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene. Yasuhiro Higashi, H. Yoshioka, Miki Yamane et al. · Proceedings of the National Academy of Sciences Open access	May 1986	562
21	Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction. Jun'ichiro Hayashi, Shigeo Ohta, Azusa Kikuchi et al. · Proceedings of the National Academy of Sciences Open access	Dec 1991	557
22	Prophylactic cranial irradiation versus observation in patients with extensive-disease small-cell lung cancer: a multicentre, randomised, open-label, phase 3 trial Toshiaki Takahashi, Takeharu Yamanaka, Takashi Seto et al. · The Lancet Oncology	23 Mar 2017	553
23	Phase III study comparing oxaliplatin plus S-1 with cisplatin plus S-1 in chemotherapy-naïve patients with advanced gastric cancer Yasuhide Yamada et al. · Annals of Oncology Open access	15 Oct 2014	546
24	Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue Masashi Suganuma · Carcinogenesis	Oct 1998	528
25	The t(8;21) translocation in acute myeloid leukemia results in production of an AML1‐MTG8 fusion transcript. Hiroyuki Miyoshi, T Kozu, Kimiko Shimizu et al. · The EMBO Journal Open access	Jul 1993	516
26	Rearrangement of the MLL Gene in Acute Lymphoblastic and Acute Myeloid Leukemias with 11q23 Chromosomal Translocations Michael J. Thirman, Heidi J. Gill, Robert C. Burnett et al. · New England Journal of Medicine Open access	23 Sep 1993	511
27	Survival benefit of liver resection for hepatocellular carcinoma associated with portal vein invasion Takashi Kokudo, Kiyoshi Hasegawa, Yutaka Matsuyama et al. · Journal of Hepatology Open access	5 Jun 2016	500
28	Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database on behalf of InSiGHT et al. · Nature Genetics Open access	22 Dec 2013	484
29	Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P45 0IA1 gene Kaname Kawajiri, Kei Nakachi, Kazue Imai et al. · FEBS Letters Open access	9 Apr 1990	477
30	Age-Related EBV-Associated B-Cell Lymphoproliferative Disorders Constitute a Distinct Clinicopathologic Group: A Study of 96 Patients Takashi Oyama et al. · Clinical Cancer Research	Sep 2007	461
31	Genetic Linkage of Lung Cancer-Associated MspI Polymorphisms with Amino Acid Replacement in the Heme Binding Region of the Human Cytochrome P450IA1 Gene1 Shin‐ichi Hayashi, Junko A. Watanabe, Kei Nakachi et al. · The Journal of Biochemistry	Sep 1991	440
32	Palonosetron plus dexamethasone versus granisetron plus dexamethasone for prevention of nausea and vomiting during chemotherapy: a double-blind, double-dummy, randomised, comparative phase III trial Mitsue Saito, Kenjiro Aogi, Ikuo Sekine et al. · The Lancet Oncology	9 Jan 2009	437
33	Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population Hayashi S-I · Lung Cancer	Mar 1994	431
34	Cross sectional study of effects of drinking green tea on cardiovascular and liver diseases Kazue Imai, Kei Nakachi · BMJ Open access	18 Mar 1995	414
35	A multicenter retrospective study of endoscopic resection for early gastric cancer Ichiro Oda, Daizo Saito, Masahiro Tada et al. · Gastric Cancer Open access	24 Nov 2006	409
36	cDNA cloning and structure of mouse putative Ah receptor Masatsugu Ema, Kazuhiro Sogawa, Nobuaki Watanabe et al. · Biochemical and Biophysical Research Communications	Apr 1992	409
37	Preventive effects of drinking green tea on cancer and cardiovascular disease: Epidemiological evidence for multiple targeting prevention Kei Nakachi, Satoru Matsuyama, Satoshi Miyaké et al. · BioFactors	2000	406
38	Continuum of overlapping clones spanning the entire human chromosome 21q Ilya M. Chumakov et al. · Nature	Oct 1992	391
39	High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma Ashraful Islam, Hajime Kageyama, Naoyuki Takada et al. · Oncogene	3 Feb 2000	388
40	Nivolumab treatment for oesophageal squamous-cell carcinoma: an open-label, multicentre, phase 2 trial Toshihiro Kudo, Yasuo Hamamoto, Ken Kato et al. · The Lancet Oncology	14 Mar 2017	386
41	An imprinted gene p57KIP2 is mutated in Beckwith–Wiedemann syndrome Izuho Hatada, Hirofumi Ohashi, Yoshimitsu Fukushima et al. · Nature Genetics	Oct 1996	385
42	Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies Yoshiaki Nakamura et al. · Nature Medicine	5 Oct 2020	380
43	High incidence of microscopic gastrointestinal stromal tumors in the stomach Kaori Kawanowa, Yuji Sakuma, Shinji Sakurai et al. · Human Pathology	26 Sep 2006	364
44	Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos Hideyuki Fujii, Takashi Sato, Sinya Kaneko et al. · The EMBO Journal Open access	15 Jul 1997	357
45	Cancer-Preventive Effects of Drinking Green Tea among a Japanese Population Kazue Imai, Kenji Suga, Kei Nakachi · Preventive Medicine	Nov 1997	352
46	Neoadjuvant chemotherapy with S-1 and cisplatin followed by D2 gastrectomy with para-aortic lymph node dissection for gastric cancer with extensive lymph node metastasis Akira Tsuburaya, Junki Mizusawa, Yoshihiro Tanaka et al. · British journal of surgery	25 Mar 2014	350
47	Prediction of the invasion depth of superficial squamous cell carcinoma based on microvessel morphology: magnifying endoscopic classification of the Japan Esophageal Society Tsuneo Oyama, Haruhiro Inoue, Miwako Arima et al. · Esophagus Open access	6 Apr 2016	347
48	Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population Genta Sawada et al. · Gastroenterology Open access	10 Feb 2016	345
49	Combination gemcitabine plus S-1 versus gemcitabine plus cisplatin for advanced/recurrent biliary tract cancer: the FUGA-BT (JCOG1113) randomized phase III clinical trial Chigusa Morizane et al. · Annals of Oncology Open access	26 Sep 2019	338
50	The runt domain identifies a new family of heterometric transcriptional regulators Hiroshi Kagoshima, Katsuya Shigesada, Masanobu Satake et al. · Trends in Genetics Review	Oct 1993	336

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.