| 1 |
Phases of Aβ-deposition in the human brain and its relevance for the development of AD
Dietmar Rudolf Thal, Udo Rüb, Mario Orantes et al. · Neurology
|
25 Jun 2002 |
3,605 |
| 2 |
Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer
Gϋnter von Minckwitz et al. · New England Journal of Medicine
Open access |
5 Dec 2018 |
2,689 |
| 3 |
Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy
Carsten Denkert et al. · The Lancet Oncology
|
8 Dec 2017 |
2,205 |
| 4 |
11 years' follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive early breast cancer: final analysis of the HERceptin Adjuvant (HERA) trial
David Cameron, Martine J Piccart, Richard D. Gelber et al. · The Lancet
Open access |
16 Feb 2017 |
1,052 |
| 5 |
Neoadjuvant carboplatin in patients with triple-negative and HER2-positive early breast cancer (GeparSixto; GBG 66): a randomised phase 2 trial
Gϋnter von Minckwitz et al. · The Lancet Oncology
|
30 Apr 2014 |
1,048 |
| 6 |
EULAR recommendations for the management of primary small and medium vessel vasculitis
Chetan B. Mukhtyar, Loı̈c Guillevin, Maria Cinta Cid et al. · Annals of the Rheumatic Diseases
Open access |
15 Apr 2008 |
994 |
| 7 |
Pulse Versus Daily Oral Cyclophosphamide for Induction of Remission in Antineutrophil Cytoplasmic Antibody—Associated Vasculitis
Kirsten de Groot, Lorraine Harper, David R.W. Jayne et al. · Annals of Internal Medicine
|
19 May 2009 |
956 |
| 8 |
Long-term patient survival in ANCA-associated vasculitis
Oliver Floßmann, Annelies E. Berden, Kirsten de Groot et al. · Annals of the Rheumatic Diseases
|
26 Nov 2010 |
946 |
| 9 |
Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline
Marco Pennazio et al. · Endoscopy
Open access |
31 Mar 2015 |
908 |
| 10 |
A randomised phase II study investigating durvalumab in addition to an anthracycline taxane-based neoadjuvant therapy in early triple-negative breast cancer: clinical results and biomarker analysis of GeparNuevo study
S. Loibl et al. · Annals of Oncology
Open access |
7 May 2019 |
714 |
| 11 |
Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin
Cyrile Anne Curat, Valérie Wegner, Coralie Sengenès et al. · Diabetologia
Open access |
22 Feb 2006 |
693 |
| 12 |
EULAR recommendations for the management of large vessel vasculitis
Chetan B. Mukhtyar, Loı̈c Guillevin, Maria Cinta Cid et al. · Annals of the Rheumatic Diseases
Open access |
15 Apr 2008 |
675 |
| 13 |
Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: a 4-year follow-up of a randomised controlled trial
Luca Gianni et al. · The Lancet Oncology
|
26 Feb 2011 |
614 |
| 14 |
From Blood Monocytes to Adipose Tissue-Resident Macrophages
Cyrile Anne Curat, Alexandra Miranville, Coralie Sengenès et al. · Diabetes
Open access |
May 2004 |
589 |
| 15 |
Clinical and molecular characteristics of HER2-low-positive breast cancer: pooled analysis of individual patient data from four prospective, neoadjuvant clinical trials
Carsten Denkert et al. · The Lancet Oncology
|
9 Jul 2021 |
581 |
| 16 |
Randomized Phase II Trial of Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: CAO/ARO/AIO-12
Emmanouil Fokas et al. · Journal of Clinical Oncology
Open access |
31 May 2019 |
556 |
| 17 |
2 years versus 1 year of adjuvant trastuzumab for HER2-positive breast cancer (HERA): an open-label, randomised controlled trial
Aron Goldhirsch et al. · The Lancet
|
17 Jul 2013 |
504 |
| 18 |
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): survival outcomes of a randomised, open-label, multicentre, phase 3 trial and their association with pathological complete response
Evandro de Azambuja et al. · The Lancet Oncology
|
14 Aug 2014 |
461 |
| 19 |
Acute Cholecystitis
Carsten N. Gutt et al. · Annals of Surgery
|
9 Aug 2013 |
460 |
| 20 |
Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase 3 trial
Michael Untch, Sibylle Loibl, Joachim Bischoff et al. · The Lancet Oncology
|
16 Jan 2012 |
459 |
| 21 |
Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Technical Review
Emanuele Rondonotti, Cristiano Spada, Samuel Nathan Adler et al. · Endoscopy
Open access |
14 Mar 2018 |
458 |
| 22 |
Early mortality in systemic vasculitis: relative contribution of adverse events and active vasculitis
Mark Alan Little, Peter Nightingale, Cornelis A. Verburgh et al. · Annals of the Rheumatic Diseases
|
3 Jul 2009 |
444 |
| 23 |
Adjuvant bevacizumab-containing therapy in triple-negative breast cancer (BEATRICE): primary results of a randomised, phase 3 trial
David Cameron et al. · The Lancet Oncology
|
6 Aug 2013 |
443 |
| 24 |
Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: phase III, randomised controlled trial
D. Jocham, Axel Richter, Lothar Hoffmann et al. · The Lancet
|
Feb 2004 |
436 |
| 25 |
Pulse versus daily oral cyclophosphamide for induction of remission in ANCA-associated vasculitis: long-term follow-up
Lorraine Harper, Matthew David Morgan, Michael W. Walsh et al. · Annals of the Rheumatic Diseases
Open access |
Dec 2011 |
432 |
| 26 |
Nab-paclitaxel versus solvent-based paclitaxel in neoadjuvant chemotherapy for early breast cancer (GeparSepto—GBG 69): a randomised, phase 3 trial
Michael Untch et al. · The Lancet Oncology
|
8 Feb 2016 |
422 |
| 27 |
An Overview of PARP Inhibitors for the Treatment of Breast Cancer
Laura Cortesi, Hope S. Rugo, Christian Jackisch · Targeted Oncology
Open access |
12 Mar 2021 |
400 |
| 28 |
Germline Mutation Status, Pathological Complete Response, and Disease-Free Survival in Triple-Negative Breast Cancer
Eric Hahnen et al. · JAMA Oncology
Open access |
17 Jul 2017 |
398 |
| 29 |
ESOPEC: prospective randomized controlled multicenter phase III trial comparing perioperative chemotherapy (FLOT protocol) to neoadjuvant chemoradiation (CROSS protocol) in patients with adenocarcinoma of the esophagus (NCT02509286)
Jens Hoeppner, Florian Lordick, Thomas Baptist Brunner et al. · BMC Cancer
Open access |
19 Jul 2016 |
360 |
| 30 |
Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I–III breast cancer (HannaH study): a phase 3, open-label, multicentre, randomised trial
Gustavo Ismael, Roberto Hegg, Susanne Muehlbauer et al. · The Lancet Oncology
|
8 Aug 2012 |
352 |
| 31 |
A conformal index (COIN) to evaluate implant quality and dose specification in brachytherapy
Dimos Baltas, Christos Kolotas, Konstantina Geramani et al. · International Journal of Radiation Oncology*Biology*Physics
Open access |
1998 |
330 |
| 32 |
Review of clinical brachytherapy uncertainties: Analysis guidelines of GEC-ESTRO and the AAPM
Christian Kirisits, Mark J. Rivard, Dimos Baltas et al. · Radiotherapy and Oncology
Open access |
30 Nov 2013 |
315 |
| 33 |
Survival analysis of carboplatin added to an anthracycline/taxane-based neoadjuvant chemotherapy and HRD score as predictor of response—final results from GeparSixto
Sibylle Loibl et al. · Annals of Oncology
Open access |
15 Oct 2018 |
308 |
| 34 |
Indications for Surgery for Obesity and Weight-Related Diseases: Position Statements from the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO)
Maurizio De Luca et al. · Obesity Surgery
Open access |
13 Jul 2016 |
297 |
| 35 |
German Association of Endocrine Surgeons practice guideline for the surgical management of malignant thyroid tumors
Henning Dralle et al. · Langenbeck s Archives of Surgery
|
Mar 2013 |
290 |
| 36 |
Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group
Carsten Denkert et al. · Modern Pathology
Open access |
Jul 2016 |
289 |
| 37 |
Neoadjuvant durvalumab improves survival in early triple-negative breast cancer independent of pathological complete response
Sibylle Loibl, Andreas Schneeweiß, Jens Huober et al. · Annals of Oncology
Open access |
9 Aug 2022 |
259 |
| 38 |
Late side-effects and cosmetic results of accelerated partial breast irradiation with interstitial brachytherapy versus whole-breast irradiation after breast-conserving surgery for low-risk invasive and in-situ carcinoma of the female breast: 5-year results of a randomised, controlled, phase 3 trial
Csaba Polgár et al. · The Lancet Oncology
|
13 Jan 2017 |
259 |
| 39 |
Functional Outcome Following Stroke Thrombectomy in Clinical Practice
Frank Arne Wollenweber et al. · Stroke
Open access |
24 Jul 2019 |
255 |
| 40 |
Intensified Neoadjuvant Chemotherapy in Early-Responding Breast Cancer: Phase III Randomized GeparTrio Study
Gϋnter von Minckwitz, Sherko Kümmel, P. Vogel et al. · JNCI Journal of the National Cancer Institute
|
8 Apr 2008 |
254 |
| 41 |
Ki67 levels as predictive and prognostic parameters in pretherapeutic breast cancer core biopsies: a translational investigation in the neoadjuvant GeparTrio trial
Carsten Denkert, Sibylle Loibl, Berit Maria Müller et al. · Annals of Oncology
Open access |
23 Aug 2013 |
249 |
| 42 |
Tumor mutational burden and immune infiltration as independent predictors of response to neoadjuvant immune checkpoint inhibition in early TNBC in GeparNuevo
Thomas Karn et al. · Annals of Oncology
Open access |
24 May 2020 |
241 |
| 43 |
Trastuzumab-Associated Cardiac Events at 8 Years of Median Follow-Up in the Herceptin Adjuvant Trial (BIG 1-01)
Evandro de Azambuja, Marion Jennifer Procter, Dirk J. van Veldhuisen et al. · Journal of Clinical Oncology
|
10 Jun 2014 |
236 |
| 44 |
The RENAISSANCE (AIO-FLOT5) trial: effect of chemotherapy alone vs. chemotherapy followed by surgical resection on survival and quality of life in patients with limited-metastatic adenocarcinoma of the stomach or esophagogastric junction – a phase III trial of the German AIO/CAO-V/CAOGI
Salah‐Eddin Al‐Batran et al. · BMC Cancer
Open access |
Dec 2017 |
235 |
| 45 |
Improved Detection of Silent Atrial Fibrillation Using 72-Hour Holter ECG in Patients With Ischemic Stroke
Martin Grond, Marek Jauss, Gerhard F. Hamann et al. · Stroke
|
16 Oct 2013 |
231 |
| 46 |
Second international consensus guidelines for breast cancer in young women (BCY2)
Shani Paluch–Shimon, Olivia Pagani, Ann H. Partridge et al. · The Breast
Open access |
7 Feb 2016 |
230 |
| 47 |
Ovarian suppression using luteinizing hormone-releasing hormone agonists during chemotherapy to preserve ovarian function and fertility of breast cancer patients: a meta-analysis of randomized studies
Matteo Lambertini, Marcello Ceppi, Francesca Benedetta Poggio et al. · Annals of Oncology
ReviewOpen access |
8 Sep 2015 |
229 |
| 48 |
Randomised controlled trial of prolonged treatment in the remission phase of ANCA-associated vasculitis
Alexandre Karras, Christian Pagnoux, Marion Haubitz et al. · Annals of the Rheumatic Diseases
Open access |
25 May 2017 |
212 |
| 49 |
Estimating the magnitude of trastuzumab effects within patient subgroups in the HERA trial
Michael Untch et al. · Annals of Oncology
Open access |
23 Feb 2008 |
198 |
| 50 |
Influence of the Angiotensin II Antagonist Valsartan on Left Ventricular Hypertrophy in Patients With Essential Hypertension
Petra Thürmann, Peter Kenedi, Andor Schmidt et al. · Circulation
Open access |
10 Nov 1998 |
198 |