| 1 |
Slowing Progression of Cardiovascular Calcification With SNF472 in Patients on Hemodialysis
Paolo Raggi, Antonio Bellasi, David A. Bushinsky et al. · Circulation
Open access |
11 Nov 2019 |
154 |
| 2 |
Characterization of SNF472 pharmacokinetics and efficacy in uremic and non-uremic rats models of cardiovascular calcification
Miguel D. Ferrer, Markus Ketteler, Fernando Tur et al. · PLoS ONE
Open access |
9 May 2018 |
52 |
| 3 |
Improvement in wound healing, pain, and quality of life after 12 weeks of SNF472 treatment: a phase 2 open-label study of patients with calciphylaxis
Vincent Mathias Brandenburg, Smeeta Sinha, José‐Vicente Torregrosa et al. · Journal of Nephrology
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10 Aug 2019 |
50 |
| 4 |
Inositol Hexakisphosphate Inhibits Osteoclastogenesis on RAW 264.7 Cells and Human Primary Osteoclasts
María del Mar Arriero, Joana Maria Ramis, Joan Perelló et al. · PLoS ONE
Open access |
14 Aug 2012 |
50 |
| 5 |
Mechanism of action of SNF472, a novel calcification inhibitor to treat vascular calcification and calciphylaxis
Joan Perelló, Miguel D. Ferrer, María del Mar Pérez Gómez et al. · British Journal of Pharmacology
Open access |
19 Jun 2020 |
48 |
| 6 |
Direct Covalent Grafting of Phytate to Titanium Surfaces through Ti–O–P Bonding Shows Bone Stimulating Surface Properties and Decreased Bacterial Adhesion
Alba Córdoba, Margarita Hierro‐Oliva, Miguel A. Pacha‐Olivenza et al. · ACS Applied Materials & Interfaces
Open access |
18 Apr 2016 |
44 |
| 7 |
A novel pharmacodynamic assay to evaluate the effects of crystallization inhibitors on calcium phosphate crystallization in human plasma
Miguel D. Ferrer, María Mar Pérez, M. M. Cànaves et al. · Scientific Reports
Open access |
25 Jul 2017 |
40 |
| 8 |
Plant phosphates, phytate and pathological calcifications in chronic kidney disease
Juan Manuel Buades, Pilar Sanchís, Joan Perelló Bestard et al. · Nefrología (English Edition)
Open access |
2017 |
40 |
| 9 |
First‐time‐in‐human randomized clinical trial in healthy volunteers and haemodialysis patients with SNF472, a novel inhibitor of vascular calcification
Joan Perelló, Pieter Joubert, Miguel D. Ferrer et al. · British Journal of Clinical Pharmacology
Open access |
3 Oct 2018 |
38 |
| 10 |
The CALCIPHYX study: a randomized, double-blind, placebo-controlled, Phase 3 clinical trial of SNF472 for the treatment of calciphylaxis
Smeeta Sinha, Lisa J. Gould, Sagar U. Nigwekar et al. · Clinical Kidney Journal
Open access |
2 Jul 2021 |
37 |
| 11 |
Fosfatos de origen vegetal, fitato y calcificaciones patológicas en la enfermedad renal crónica
Juan Manuel Buades, Pilar Sanchís Cortés, Joan Perelló Bestard et al. · Nefrología
Open access |
6 Oct 2016 |
37 |
| 12 |
Validation of an LC–MS bioanalytical method for quantification of phytate levels in rat, dog and human plasma
Fernando Tur, Eva Tur, Irene Lenthéric et al. · Journal of Chromatography B
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8 Apr 2013 |
34 |
| 13 |
SNF472, a novel inhibitor of vascular calcification, could be administered during hemodialysis to attain potentially therapeutic phytate levels
Joan Perelló, Miquel Gómez, Miguel D. Ferrer et al. · Journal of Nephrology
Open access |
19 Jan 2018 |
32 |
| 14 |
Differential Response of MC3T3-E1 and Human Mesenchymal Stem Cells to Inositol Hexakisphosphate
María del Mar Arriero, Joana Maria Ramis, Joan Perelló et al. · Cellular Physiology and Biochemistry
Open access |
2012 |
32 |
| 15 |
Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview
Maria Bogdanova, Arsenii Zabirnyk, Anna Malashicheva et al. · Frontiers in Pharmacology
Open access |
2 Jun 2022 |
27 |
| 16 |
Effects of Myo-inositol Hexaphosphate (SNF472) on Bone Mineral Density in Patients Receiving Hemodialysis
David A. Bushinsky, Paolo Raggi, Jordi Bover et al. · Clinical Journal of the American Society of Nephrology
Open access |
7 Apr 2021 |
22 |
| 17 |
A Novel Ex Vivo Model of Aortic Valve Calcification. A Preliminary Report
Arsenii Zabirnyk, María del Mar Pérez Gómez, Marc Blasco et al. · Frontiers in Pharmacology
Open access |
17 Dec 2020 |
22 |
| 18 |
SNF472, a novel anti-crystallization agent, inhibits induced calcification in an in vitro model of human aortic valve calcification
Arsenii Zabirnyk, Miguel D. Ferrer, Maria Bogdanova et al. · Vascular Pharmacology
Open access |
19 Aug 2019 |
21 |
| 19 |
Effects of SNF472, a Novel Inhibitor of Hydroxyapatite Crystallization in Patients Receiving Hemodialysis — Subgroup Analyses of the CALIPSO Trial
Paolo Raggi, Antonio Bellasi, Smeeta Sinha et al. · Kidney International Reports
Open access |
4 Nov 2020 |
18 |
| 20 |
Hypothesis: Phytate is an important unrecognised nutrient and potential intravenous drug for preventing vascular calcification
Pieter Joubert, Markus Ketteler, Carolina Salcedo et al. · Medical Hypotheses
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14 Jul 2016 |
18 |
| 21 |
A phase 1b randomized, placebo‐controlled clinical trial with SNF472 in haemodialysis patients
Carolina Salcedo, Pieter Joubert, Miguel D. Ferrer et al. · British Journal of Clinical Pharmacology
Open access |
11 Jan 2019 |
16 |
| 22 |
Trial design and baseline characteristics of CaLIPSO: a randomized, double-blind placebo-controlled trial of SNF472 in patients receiving haemodialysis with cardiovascular calcification
Antonio Bellasi, Paolo Raggi, Jordi Bover et al. · Clinical Kidney Journal
Open access |
28 Sep 2019 |
12 |
| 23 |
Phytate levels in biological fluids of mammals
Joan Perelló, Felix Grases · Journal of Chromatography B
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3 Jan 2014 |
9 |
| 24 |
A novel assay to measure calcification propensity: from laboratory to humans
María Mar Pérez, Miguel D. Ferrer, Marta Lazo-Rodríguez et al. · Scientific Reports
Open access |
16 Oct 2020 |
8 |
| 25 |
P1234SNF472 IMPROVES LIMB BLOOD PERFUSION AND WALKING ABILITY IN A PERIPHERAL ARTERY DISEASE VASCULAR CALCIFICATION RAT MODEL
Firas Bassissi, Miguel David Ferrer Reynes, María Mar Pérez et al. · Nephrology Dialysis Transplantation
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Jun 2020 |
2 |
| 26 |
Mechanistic insights into protonation state as a critical factor in hFPPS enzyme inhibition
David Fernández, Joaquín Ortega‐Castro, Laura Mariño et al. · Journal of Computer-Aided Molecular Design
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16 Jun 2015 |
2 |
| 27 |
Hexasodium Fytate (SNF472 or CSL525) Inhibits Ectopic Calcification in Various Pseudoxanthoma Elasticum and Calcinosis Cutis Animal Models
Miguel D. Ferrer, Maria del Mar Pérez-Ferrer, Marc Blasco et al. · Pharmaceuticals
Open access |
14 Apr 2025 |
1 |
| 28 |
Hexasodium fytate exposure-response correlations in a randomized, placebo-controlled study of patients on dialysis with cardiovascular calcification
Joan Perelló, Joan J. Alberti, Juan Vicente Torres et al. · Frontiers in Pharmacology
Open access |
7 Feb 2024 |
0 |
| 29 |
FC 107SNF472 ATTENUATES THE PROGRESSION OF FEMORAL ARTERY CALCIFICATION AND RECOVERS LIMB BLOOD PERFUSION AND WALKING ABILITY IN A RAT MODEL OF PERIPHERAL ARTERY DISEASE
Firas Bassissi, Miguel David Ferrer Reynes, María Mar Pérez et al. · Nephrology Dialysis Transplantation
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May 2021 |
0 |
| 30 |
SO086SNF472 CONSISTENTLY SLOWS PROGRESSION OF CORONARY CALCIFICATION IN PATIENTS ON HEMODIALYSIS: SUBGROUP ANALYSIS OF THE CALIPSO STUDY
Paolo Raggi, Antonio Bellasi, David A. Bushinsky et al. · Nephrology Dialysis Transplantation
Open access |
Jun 2020 |
0 |
| 31 |
P0884MYO-INOSITOL HEXAPHOSPHATE PEGYLATION IMPROVES BIOAVAILABILITY BUT REDUCES ITS ANTI-VASCULAR CALCIFICATION EFFECT IN RATS
María Mar Pérez, Miguel David Ferrer Reynes, Joaquín Ortega‐Castro et al. · Nephrology Dialysis Transplantation
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Jun 2020 |
0 |
| 32 |
P4487Inhibition of aortic valve calcification by SNF472 in vitro
Arsenii Zabirnyk, Maria Bogdanova, Miguel D. Ferrer et al. · European Heart Journal
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Oct 2019 |
0 |
| 33 |
FP446IN VITRO EFFECTS OF SNF472 ON OSTEOBLAST CELL CULTURE
Geert J. S. Behets, Miguel D. Ferrer, María Mar Pérez et al. · Nephrology Dialysis Transplantation
Open access |
Jun 2019 |
0 |
| 34 |
FP633A DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED PHASE 2B STUDY TO ASSESS THE EFFECT OF SNF472 ADDED TO STANDARD OF CARE ON PROGRESSION OF CARDIOVASCULAR CALCIFICATION IN PATIENTS WITH END-STAGE RENAL DISEASE ON MAINTENANCE HAEMODIALYSIS (CaLIPSO STUDY)
Paolo Raggi, Antonio Bellasi, Jordi Bover Sanjuán et al. · Nephrology Dialysis Transplantation
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Jun 2019 |
0 |
| 35 |
SP655DESIGN OF A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO ASSESS THE EFFICACY AND SAFETY OF SNF472 FOR THE TREATMENT OF CALCIFIC UREMIC ARTERIOLOPATHY (CALCIPHYLAXIS)
Smeeta Sinha, Glenn Matthew Chertow, Vincent Mathias Brandenburg et al. · Nephrology Dialysis Transplantation
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Jun 2019 |
0 |