| 1 |
IgG Subclasses and Allotypes: From Structure to Effector Functions
Gestur Vidarsson, Gillian Dekkers, Theo T. Rispens · Frontiers in Immunology
Open access |
20 Oct 2014 |
2,735 |
| 2 |
Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
Catherine Dostert, Virginie Pétrilli, Robin van Bruggen et al. · Science
Open access |
10 Apr 2008 |
2,685 |
| 3 |
Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
Thomas Kuilman, Chrysiis Michaloglou, Liesbeth C.W. Vredeveld et al. · Cell
Open access |
Jun 2008 |
2,107 |
| 4 |
Specific autoantibodies precede the symptoms of rheumatoid arthritis: A study of serial measurements in blood donors
Markus M. J. Nielen, Dirkjan van Schaardenburg, Henk W. Reesink et al. · Arthritis & Rheumatism
Open access |
Feb 2004 |
1,868 |
| 5 |
Large-scale association analysis identifies new risk loci for coronary artery disease
Panos Deloukas et al. · Nature Genetics
Open access183 authors |
2 Dec 2012 |
1,681 |
| 6 |
Allergy, Parasites, and the Hygiene Hypothesis
Maria Yazdanbakhsh, Peter G. Kremsner, Ronald van Ree · Science
|
19 Apr 2002 |
1,539 |
| 7 |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease
William John Astle et al. · Cell
Open access |
Nov 2016 |
1,429 |
| 8 |
Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
Philip J. M. Brouwer et al. · Science
Open access |
15 Jun 2020 |
1,356 |
| 9 |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
Eli A. Stahl et al. · Nature Genetics
Open access |
9 May 2010 |
1,289 |
| 10 |
Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids
Krijn K. Dijkstra et al. · Cell
Open access |
9 Aug 2018 |
1,129 |
| 11 |
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Kyriaki Michailidou et al. · Nature Genetics
Open access222 authors |
27 Mar 2013 |
1,109 |
| 12 |
Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19
Irani Thevarajan, Thi H. O. Nguyen, Marios Koutsakos et al. · Nature Medicine
Open access |
16 Mar 2020 |
1,107 |
| 13 |
Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes
Laura K. Mackay et al. · Science
Open access |
21 Apr 2016 |
1,038 |
| 14 |
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
Andrea Cossarizza et al. · European Journal of Immunology
Open access436 authors |
Oct 2019 |
1,014 |
| 15 |
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors
Stephen A. Migueles, Alisha C. Laborico, W. Lesley Shupert et al. · Nature Immunology
|
7 Oct 2002 |
1,012 |
| 16 |
Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange
Marijn van der Neut Kolfschoten, Janine Schuurman, Mario Losen et al. · Science
|
13 Sep 2007 |
990 |
| 17 |
EAACI Molecular Allergology User's Guide
Paolo Maria Matricardi et al. · Pediatric Allergy and Immunology
Open access |
May 2016 |
926 |
| 18 |
International consensus statement on the peri‐operative management of anaemia and iron deficiency
Manuel Múñoz, Austin George Acheson, Michael Auerbach et al. · Anaesthesia
Open access |
20 Dec 2016 |
876 |
| 19 |
The Interaction Between Signal Regulatory Protein Alpha (SIRPα) and CD47: Structure, Function, and Therapeutic Target
A. Neil Barclay, Timo K. van den Berg · Annual Review of Immunology
Review |
11 Nov 2013 |
860 |
| 20 |
C-Reactive Protein as a Cardiovascular Risk Factor
Wim K. Lagrand, Cees A. Visser, Willem T. Hermens et al. · Circulation
Open access |
6 Jul 1999 |
839 |
| 21 |
Immunoglobulin G4: an odd antibody
Rob C. Aalberse, Steven O. Stapel, Janine Schuurman et al. · Clinical & Experimental Allergy
|
16 Feb 2009 |
836 |
| 22 |
Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells
Lu Chen et al. · Cell
Open access |
Nov 2016 |
793 |
| 23 |
Development of Antidrug Antibodies Against Adalimumab and Association With Disease Activity and Treatment Failure During Long-term Follow-up
G. M. Bartelds · JAMA
|
12 Apr 2011 |
787 |
| 24 |
Persistent immune activation in HIV-1 infection is associated with progression to AIDS
Mette D. Hazenberg, Sigrid A. Otto, Birgit HB van Benthem et al. · AIDS
|
27 Aug 2003 |
786 |
| 25 |
Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial
Merih I. Baharoglu, Charlotte Cordonnier, Rustam Al‐Shahi Salman et al. · The Lancet
Open access |
10 May 2016 |
773 |
| 26 |
Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials
Nicholas J. Viney, Julian C. van Capelleveen, Richard S. Geary et al. · The Lancet
|
21 Sep 2016 |
759 |
| 27 |
Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts
Willem J. H. van Berkel, Nanne M. Kamerbeek, Marco W. Fraaije · Journal of Biotechnology
Open access |
22 May 2006 |
718 |
| 28 |
Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data
Vincent H. J. van der Velden, Giovanni Cazzaniga, André Schrauder et al. · Leukemia
Open access |
8 Feb 2007 |
711 |
| 29 |
Chronic Granulomatous Disease: The European Experience
J. Merlijn van den Berg, Elsbeth van Koppen, Anders Åhlin et al. · PLoS ONE
Open access |
20 Apr 2009 |
697 |
| 30 |
Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injury
Philipp Krüger, Mona Saffarzadeh, Alexander N.R. Weber et al. · PLoS Pathogens
Open access |
12 Mar 2015 |
675 |
| 31 |
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
Australian Ovarian Cancer Study et al. · Nature
Open access202 authors |
23 Jul 2014 |
667 |
| 32 |
Clinical picture and treatment of 2212 patients with common variable immunodeficiency
Benjamin Gathmann et al. · Journal of Allergy and Clinical Immunology
|
28 Feb 2014 |
644 |
| 33 |
Patient Blood Management
Markus M. Mueller et al. · JAMA
|
12 Mar 2019 |
643 |
| 34 |
Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality
Quinten Remijsen, Taco Willem Kuijpers, Ellen Wirawan et al. · Cell Death and Differentiation
Open access |
4 Feb 2011 |
618 |
| 35 |
Stroke in COVID-19: A systematic review and meta-analysis
Stefania Nannoni, Rosa de Groot, Steven Bell et al. · International Journal of Stroke
ReviewOpen access |
26 Oct 2020 |
594 |
| 36 |
Whole-genome sequencing of patients with rare diseases in a national health system
Ernest Turro et al. · Nature
Open access512 authors |
24 Jun 2020 |
589 |
| 37 |
Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans
Ineke den Braber, Tendai Mugwagwa, Nienke Vrisekoop et al. · Immunity
Open access |
Feb 2012 |
582 |
| 38 |
The CD47‐SIRPα signaling axis as an innate immune checkpoint in cancer
Hanke L. Matlung, Katka Szilagyi, Neil Barclay et al. · Immunological Reviews
ReviewOpen access |
Mar 2017 |
581 |
| 39 |
Cellular origin and procoagulant properties of microparticles in meningococcal sepsis
Rienk Nieuwland, René J. Berckmans, Sarah McGregor et al. · Blood
|
Feb 2000 |
579 |
| 40 |
Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma
Maartje W. Rohaan et al. · New England Journal of Medicine
Open access |
7 Dec 2022 |
577 |
| 41 |
Clinical response to adalimumab: relationship to anti-adalimumab antibodies and serum adalimumab concentrations in rheumatoid arthritis
G. M. Bartelds, Carla Ann Wijbrandts, Michael Twahier Nurmohamed et al. · Annals of the Rheumatic Diseases
Open access |
14 Feb 2007 |
571 |
| 42 |
Simultaneous Detection of 15 Human Cytokines in a Single Sample of Stimulated Peripheral Blood Mononuclear Cells
Wilco de Jager, Henk te Velthuis, Berent J. Prakken et al. · Clinical and Vaccine Immunology
Open access |
2003 |
571 |
| 43 |
Breaching multiple barriers: leukocyte motility through venular walls and the interstitium
Sussan Nourshargh, Peter Lodewijk Hordijk, Michael Sixt · Nature Reviews Molecular Cell Biology
Review |
23 Apr 2010 |
569 |
| 44 |
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations
Thomas F. Eleveld et al. · Nature Genetics
Open access |
29 Jun 2015 |
568 |
| 45 |
Diagnosis and treatment of autoimmune hemolytic anemia in adults: Recommendations from the First International Consensus Meeting
Ulrich Jäger, Wilma Barcellini, Catherine M. Broome et al. · Blood Reviews
Open access |
5 Dec 2019 |
561 |
| 46 |
Guidelines for the use of flow cytometry and cell sorting in immunological studies *
Andrea Cossarizza et al. · European Journal of Immunology
Open access236 authors |
Oct 2017 |
560 |
| 47 |
Age of Transfused Blood in Critically Ill Adults
Jacques Lacroix et al. · New England Journal of Medicine
Open access |
17 Mar 2015 |
560 |
| 48 |
Common variants at CD40 and other loci confer risk of rheumatoid arthritis
Soumya Raychaudhuri et al. · Nature Genetics
Open access |
11 Sep 2008 |
546 |
| 49 |
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
Australian Cancer Study et al. · Nature Genetics
Open access443 authors |
27 Mar 2013 |
544 |
| 50 |
Assessment of antibodies to double-stranded DNA induced in rheumatoid arthritis patients following treatment with infliximab, a monoclonal antibody to tumor necrosis factor α: Findings in open-label and randomized placebo-controlled trials
Peter J Charles, Ruud J.T. Smeenk, Jan L. de Jong et al. · Arthritis & Rheumatism
|
Nov 2000 |
532 |