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Most cited papers from Sanquin

What are the most cited papers from Sanquin?

The most cited paper from Sanquin is "IgG Subclasses and Allotypes: From Structure to Effector Functions" (Gestur Vidarsson, Gillian Dekkers, Theo T. Rispens, 2014), with 2,735 citations. Next come "Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica" (2,685) and "Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network" (2,107).

Showing 50 of 60 papers. Every paper with more than 454 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 IgG Subclasses and Allotypes: From Structure to Effector Functions Gestur Vidarsson, Gillian Dekkers, Theo T. Rispens · Frontiers in Immunology Open access 20 Oct 2014 2,735
2 Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica Catherine Dostert, Virginie Pétrilli, Robin van Bruggen et al. · Science Open access 10 Apr 2008 2,685
3 Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network Thomas Kuilman, Chrysiis Michaloglou, Liesbeth C.W. Vredeveld et al. · Cell Open access Jun 2008 2,107
4 Specific autoantibodies precede the symptoms of rheumatoid arthritis: A study of serial measurements in blood donors Markus M. J. Nielen, Dirkjan van Schaardenburg, Henk W. Reesink et al. · Arthritis & Rheumatism Open access Feb 2004 1,868
5 Large-scale association analysis identifies new risk loci for coronary artery disease Panos Deloukas et al. · Nature Genetics Open access183 authors 2 Dec 2012 1,681
6 Allergy, Parasites, and the Hygiene Hypothesis Maria Yazdanbakhsh, Peter G. Kremsner, Ronald van Ree · Science 19 Apr 2002 1,539
7 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease William John Astle et al. · Cell Open access Nov 2016 1,429
8 Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability Philip J. M. Brouwer et al. · Science Open access 15 Jun 2020 1,356
9 Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci Eli A. Stahl et al. · Nature Genetics Open access 9 May 2010 1,289
10 Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids Krijn K. Dijkstra et al. · Cell Open access 9 Aug 2018 1,129
11 Large-scale genotyping identifies 41 new loci associated with breast cancer risk Kyriaki Michailidou et al. · Nature Genetics Open access222 authors 27 Mar 2013 1,109
12 Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 Irani Thevarajan, Thi H. O. Nguyen, Marios Koutsakos et al. · Nature Medicine Open access 16 Mar 2020 1,107
13 Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes Laura K. Mackay et al. · Science Open access 21 Apr 2016 1,038
14 Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) Andrea Cossarizza et al. · European Journal of Immunology Open access436 authors Oct 2019 1,014
15 HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors Stephen A. Migueles, Alisha C. Laborico, W. Lesley Shupert et al. · Nature Immunology 7 Oct 2002 1,012
16 Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange Marijn van der Neut Kolfschoten, Janine Schuurman, Mario Losen et al. · Science 13 Sep 2007 990
17 EAACI Molecular Allergology User's Guide Paolo Maria Matricardi et al. · Pediatric Allergy and Immunology Open access May 2016 926
18 International consensus statement on the peri‐operative management of anaemia and iron deficiency Manuel Múñoz, Austin George Acheson, Michael Auerbach et al. · Anaesthesia Open access 20 Dec 2016 876
19 The Interaction Between Signal Regulatory Protein Alpha (SIRPα) and CD47: Structure, Function, and Therapeutic Target A. Neil Barclay, Timo K. van den Berg · Annual Review of Immunology Review 11 Nov 2013 860
20 C-Reactive Protein as a Cardiovascular Risk Factor Wim K. Lagrand, Cees A. Visser, Willem T. Hermens et al. · Circulation Open access 6 Jul 1999 839
21 Immunoglobulin G4: an odd antibody Rob C. Aalberse, Steven O. Stapel, Janine Schuurman et al. · Clinical & Experimental Allergy 16 Feb 2009 836
22 Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells Lu Chen et al. · Cell Open access Nov 2016 793
23 Development of Antidrug Antibodies Against Adalimumab and Association With Disease Activity and Treatment Failure During Long-term Follow-up G. M. Bartelds · JAMA 12 Apr 2011 787
24 Persistent immune activation in HIV-1 infection is associated with progression to AIDS Mette D. Hazenberg, Sigrid A. Otto, Birgit HB van Benthem et al. · AIDS 27 Aug 2003 786
25 Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial Merih I. Baharoglu, Charlotte Cordonnier, Rustam Al‐Shahi Salman et al. · The Lancet Open access 10 May 2016 773
26 Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials Nicholas J. Viney, Julian C. van Capelleveen, Richard S. Geary et al. · The Lancet 21 Sep 2016 759
27 Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts Willem J. H. van Berkel, Nanne M. Kamerbeek, Marco W. Fraaije · Journal of Biotechnology Open access 22 May 2006 718
28 Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data Vincent H. J. van der Velden, Giovanni Cazzaniga, André Schrauder et al. · Leukemia Open access 8 Feb 2007 711
29 Chronic Granulomatous Disease: The European Experience J. Merlijn van den Berg, Elsbeth van Koppen, Anders Åhlin et al. · PLoS ONE Open access 20 Apr 2009 697
30 Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injury Philipp Krüger, Mona Saffarzadeh, Alexander N.R. Weber et al. · PLoS Pathogens Open access 12 Mar 2015 675
31 Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche Australian Ovarian Cancer Study et al. · Nature Open access202 authors 23 Jul 2014 667
32 Clinical picture and treatment of 2212 patients with common variable immunodeficiency Benjamin Gathmann et al. · Journal of Allergy and Clinical Immunology 28 Feb 2014 644
33 Patient Blood Management Markus M. Mueller et al. · JAMA 12 Mar 2019 643
34 Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality Quinten Remijsen, Taco Willem Kuijpers, Ellen Wirawan et al. · Cell Death and Differentiation Open access 4 Feb 2011 618
35 Stroke in COVID-19: A systematic review and meta-analysis Stefania Nannoni, Rosa de Groot, Steven Bell et al. · International Journal of Stroke ReviewOpen access 26 Oct 2020 594
36 Whole-genome sequencing of patients with rare diseases in a national health system Ernest Turro et al. · Nature Open access512 authors 24 Jun 2020 589
37 Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans Ineke den Braber, Tendai Mugwagwa, Nienke Vrisekoop et al. · Immunity Open access Feb 2012 582
38 The CD47‐SIRPα signaling axis as an innate immune checkpoint in cancer Hanke L. Matlung, Katka Szilagyi, Neil Barclay et al. · Immunological Reviews ReviewOpen access Mar 2017 581
39 Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Rienk Nieuwland, René J. Berckmans, Sarah McGregor et al. · Blood Feb 2000 579
40 Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma Maartje W. Rohaan et al. · New England Journal of Medicine Open access 7 Dec 2022 577
41 Clinical response to adalimumab: relationship to anti-adalimumab antibodies and serum adalimumab concentrations in rheumatoid arthritis G. M. Bartelds, Carla Ann Wijbrandts, Michael Twahier Nurmohamed et al. · Annals of the Rheumatic Diseases Open access 14 Feb 2007 571
42 Simultaneous Detection of 15 Human Cytokines in a Single Sample of Stimulated Peripheral Blood Mononuclear Cells Wilco de Jager, Henk te Velthuis, Berent J. Prakken et al. · Clinical and Vaccine Immunology Open access 2003 571
43 Breaching multiple barriers: leukocyte motility through venular walls and the interstitium Sussan Nourshargh, Peter Lodewijk Hordijk, Michael Sixt · Nature Reviews Molecular Cell Biology Review 23 Apr 2010 569
44 Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations Thomas F. Eleveld et al. · Nature Genetics Open access 29 Jun 2015 568
45 Diagnosis and treatment of autoimmune hemolytic anemia in adults: Recommendations from the First International Consensus Meeting Ulrich Jäger, Wilma Barcellini, Catherine M. Broome et al. · Blood Reviews Open access 5 Dec 2019 561
46 Guidelines for the use of flow cytometry and cell sorting in immunological studies * Andrea Cossarizza et al. · European Journal of Immunology Open access236 authors Oct 2017 560
47 Age of Transfused Blood in Critically Ill Adults Jacques Lacroix et al. · New England Journal of Medicine Open access 17 Mar 2015 560
48 Common variants at CD40 and other loci confer risk of rheumatoid arthritis Soumya Raychaudhuri et al. · Nature Genetics Open access 11 Sep 2008 546
49 Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer Australian Cancer Study et al. · Nature Genetics Open access443 authors 27 Mar 2013 544
50 Assessment of antibodies to double-stranded DNA induced in rheumatoid arthritis patients following treatment with infliximab, a monoclonal antibody to tumor necrosis factor α: Findings in open-label and randomized placebo-controlled trials Peter J Charles, Ruud J.T. Smeenk, Jan L. de Jong et al. · Arthritis & Rheumatism Nov 2000 532

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.