| 1 |
Antibodies to watch in 2020
Hélène Kaplon, Mrinalini Muralidharan, Zita Schneider et al. · mAbs
Open access |
18 Dec 2019 |
442 |
| 2 |
Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape
Constance J. Martin et al. · Science Translational Medicine
|
25 Mar 2020 |
232 |
| 3 |
Advances and limitations for the treatment of spinal muscular atrophy
John W. Day, Kelly Howell, Amy Place et al. · BMC Pediatrics
Open access |
3 Nov 2022 |
138 |
| 4 |
Infectious Disease as an Evolutionary Paradigm
Joshua Lederberg · Emerging infectious diseases
Open access |
Dec 1997 |
123 |
| 5 |
Specific inhibition of myostatin activation is beneficial in mouse models of SMA therapy
Kimberly K. Long, Karen M. O’Shea, Ramzi J. Khairallah et al. · Human Molecular Genetics
Open access |
7 Nov 2018 |
112 |
| 6 |
Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis
Alan C. Chen, Adriana Donovan, Renée M. Ned et al. · Proceedings of the National Academy of Sciences
Open access |
31 Aug 2015 |
98 |
| 7 |
Blocking extracellular activation of myostatin as a strategy for treating muscle wasting
Michelle Pirruccello, Justin Jackson, Stefan Wawersik et al. · Scientific Reports
Open access |
29 Jan 2018 |
94 |
| 8 |
Product of the steel locus suppresses apoptosis in hemopoietic cells. Comparison with pathways activated by granulocyte macrophage colony-stimulating factor.
Julio Roberto Cáceres‐Cortés, Daniel Rajotte, J. Dumouchel et al. · Journal of Biological Chemistry
Open access |
Apr 1994 |
88 |
| 9 |
Safety and Efficacy of Apitegromab in Patients With Spinal Muscular Atrophy Types 2 and 3
Thomas O. Crawford, Basil T. Darras, John Day et al. · Neurology
Open access |
8 Feb 2024 |
53 |
| 10 |
A Randomized Phase 1 Safety, Pharmacokinetic and Pharmacodynamic Study of the Novel Myostatin Inhibitor Apitegromab (SRK-015): A Potential Treatment for Spinal Muscular Atrophy
Doreen Barrett, Sanela Bilic, Yung H. Chyung et al. · Advances in Therapy
Open access |
8 May 2021 |
47 |
| 11 |
Rare deleterious mutations of the gene EFR3A in autism spectrum disorders
Abha R. Gupta, Michelle Pirruccello, Feng Cheng et al. · Molecular Autism
Open access |
2014 |
42 |
| 12 |
Risk-Based Control Strategies of Recombinant Monoclonal Antibody Charge Variants
Alain Beck, Christine Nowak, Deborah Meshulam et al. · Antibodies
Open access |
20 Nov 2022 |
41 |
| 13 |
Measuring Soil Electrical Resistivity Using a Resistivity Box and a Resistivity Probe
Sekharan Sreedeep, A.C. Reshma, Devendra Narain Singh · Geotechnical Testing Journal
|
25 May 2004 |
40 |
| 14 |
Stability of Protein Pharmaceuticals: Recent Advances
Mark Cornell Manning, Ryan E. Holcomb, R. W. Payne et al. · Pharmaceutical Research
|
27 Jun 2024 |
37 |
| 15 |
Tolloid cleavage activates latent GDF8 by priming the pro‐complex for dissociation
Viet Q. Le, Roxana E. Iacob, Yuan Tian et al. · The EMBO Journal
Open access |
17 Jan 2018 |
35 |
| 16 |
Preclinical characterization of dostarlimab, a therapeutic anti-PD-1 antibody with potent activity to enhance immune function in in vitro cellular assays and in vivo animal models
Sujatha Kumar, Srimoyee Ghosh, Geeta Sharma et al. · mAbs
Open access |
2021 |
34 |
| 17 |
Federated Learning and Data Privacy: A Review of Challenges and Opportunities
Praveen Kumar Myakala, Chiranjeevi Bura, Anil Kumar Jonnalagadda · International Journal of Research Publication and Reviews
Open access |
Dec 2024 |
32 |
| 18 |
Recent Studies of Image and Soft Computing Techniques for Plant Disease Recognition and Classification
Hiteshwari Sabrol, Satish Kumar · International Journal of Computer Applications
Open access |
17 Sep 2015 |
32 |
| 19 |
Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-β
Jun Kuai, Lidia Mosyak, Jonathan C.W. Brooks et al. · Biochemistry
|
24 Feb 2015 |
32 |
| 20 |
FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models
Timothy Weeden et al. · Communications Medicine
Open access |
18 Jan 2025 |
31 |
| 21 |
Neutralizing Antibody Validation Testing and Reporting Harmonization
Heather A. Myler et al. · The AAPS Journal
Open access |
8 Jul 2023 |
30 |
| 22 |
Population pharmacokinetics and exposure–response of anti‐programmed cell death protein‐1 monoclonal antibody dostarlimab in advanced solid tumours
Murad R. Melhem, Eva Hanze, Sharon M. Lu et al. · British Journal of Clinical Pharmacology
Open access |
31 Mar 2022 |
29 |
| 23 |
CXA-10, a Nitrated Fatty Acid, Is Renoprotective in Deoxycorticosterone Acetate-Salt Nephropathy
CYNTHIA M. ARBEENY, Hong Ling, Mandy M. Smith et al. · Journal of Pharmacology and Experimental Therapeutics
Open access |
21 Mar 2019 |
29 |
| 24 |
Safety and efficacy of apitegromab in nonambulatory type 2 or type 3 spinal muscular atrophy (SAPPHIRE): a phase 3, double-blind, randomised, placebo-controlled trial
Thomas O. Crawford et al. · The Lancet Neurology
Open access |
13 Aug 2025 |
28 |
| 25 |
Nonclinical Development of SRK-181: An Anti-Latent TGFβ1 Monoclonal Antibody for the Treatment of Locally Advanced or Metastatic Solid Tumors
Brian T. Welsh, Ryan Faucette, Sanela Bilic et al. · International Journal of Toxicology
Open access |
19 Mar 2021 |
27 |
| 26 |
Structural basis of specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015
Kevin B. Dagbay, Erin Treece, Frederick C. Streich et al. · Journal of Biological Chemistry
Open access |
20 Feb 2020 |
27 |
| 27 |
An antibody that inhibits TGF-β1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis
Justin Jackson et al. · Science Signaling
|
9 Jul 2024 |
23 |
| 28 |
2D-LC–MS/MS to Measure Cleaved High-Molecular-Weight Kininogen in Human Plasma as A Biomarker for C1-Inh-Hae
Guodong Zhang, Daniel J. Sexton, Ryan Faucette et al. · Bioanalysis
Open access |
Oct 2017 |
23 |
| 29 |
The effect of nitrogen on cereal yields
E. R. Bullen, W. J. Lessells · The Journal of Agricultural Science
|
Oct 1957 |
22 |
| 30 |
Biophysical and Immunological Characterization and In Vivo Pharmacokinetics and Toxicology in Nonhuman Primates of the Anti-PD-1 Antibody Pembrolizumab
Beth Hutchins et al. · Molecular Cancer Therapeutics
|
30 Mar 2020 |
21 |
| 31 |
Long-term efficacy, safety, and patient-reported outcomes of apitegromab in patients with spinal muscular atrophy: results from the 36-month TOPAZ study
Thomas O. Crawford, John W. Day, Darryl C. De Vivo et al. · Frontiers in Neurology
Open access |
22 Jul 2024 |
20 |
| 32 |
An Integrated Analysis of Dostarlimab Immunogenicity
Sharon M. Lu, Ronald R. Bowsher, Amanda Clancy et al. · The AAPS Journal
Open access |
29 Jul 2021 |
18 |
| 33 |
Cigarette Smoking in a Cohort of Sydney Schoolchildren: 1971-1974
Stephen Leeder, JENNIFER K. PEAT, Ann J. Woolcock et al. · Australian and New Zealand Journal of Medicine
|
Oct 1977 |
13 |
| 34 |
Aligning Germline Cancer Predisposition With Tumor-Based Next-Generation Sequencing for Modern Oncology Diagnosis, Interception, and Therapeutic Development
Timothy Anthony Yap, Zsofia Kinga Stadler, Leigh Anne Stout et al. · American Society of Clinical Oncology Educational Book
|
Jun 2023 |
12 |
| 35 |
Preclinical Safety Assessment and Toxicokinetics of Apitegromab, an Antibody Targeting Proforms of Myostatin for the Treatment of Muscle-Atrophying Disease
Brian T. Welsh, Shaun M. Cote, Deborah Meshulam et al. · International Journal of Toxicology
Open access |
Jul 2021 |
11 |
| 36 |
Apitegromab for lean mass preservation during tirzepatide-induced weight loss: a randomized, double-blind, placebo-controlled phase 2 trial
Richard E. Pratley, Douglas Scott Denham, Rupal Trivedi et al. · Nature Medicine
Open access |
8 Jun 2026 |
10 |
| 37 |
Linavonkibart and pembrolizumab in immune checkpoint blockade-resistant advanced solid tumors: a phase 1 trial
Timothy A. Yap, Randy F. Sweis, Ulka Vaishampayan et al. · Nature Medicine
Open access |
13 Jan 2026 |
8 |
| 38 |
Presynapses are mitophagy pit stops that prevent axon degeneration
Wai Kit Lam, Runa S. J. Lindblom, Bridget Milky et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
9 Sep 2024 |
8 |
| 39 |
A Review On Google Earth Engine: An Open Access Cloud Analysis Platform For Planetary Scale Satellite Data
Rohini Sangeetham, Nagamuthu Krishnan S S · E3S Web of Conferences
Conference paperOpen access |
2024 |
6 |
| 40 |
A Sensitive and Selective Immunoassay for the Quantitation of Serum Latent Myostatin after In Vivo Administration of SRK-015, a Selective Inhibitor of Myostatin Activation
Shaun M. Cote, Justin Jackson, Michelle Pirruccello et al. · SLAS DISCOVERY
Open access |
26 Jul 2019 |
6 |
| 41 |
Comparative Study of Parallel Programming Models to Compute Complex Algorithm
Mukul Mani Sharma, Pradeep Soni · International Journal of Computer Applications
Open access |
18 Jun 2014 |
6 |
| 42 |
Remaining Burden of Spinal Muscular Atrophy Among Treated Patients: A Survey of Patients and Caregivers
Julie A. Parsons, Natalie Land, Melissa Culhane Maravić et al. · Annals of Clinical and Translational Neurology
Open access |
6 Jul 2025 |
5 |
| 43 |
Effect of Pranayama and Meditation on Emotional Intelligence among Undergraduate Students: A Randomized Controlled Study
Jairam Kushwaha, Vatsala Thapliyal, Sachin Kumar Sharma et al. · International Journal of Ayurvedic Medicine
Open access |
10 Jul 2024 |
5 |
| 44 |
Selective Myostatin Inhibition Spares Sublesional Muscle Mass and Myopenia-Related Dysfunction after Severe Spinal Cord Contusion in Mice
Gregory E. Bigford, Adriana Donovan, Micah T. Webster et al. · Journal of Neurotrauma
|
29 Oct 2021 |
5 |
| 45 |
Assessment of Water Quality of Tighra Reservoir using Weighted Arithmetic Water Quality Index (WA-WQI)
Rishabh Kumar, Jay Singh Rajput, Abhishek Kumar Saxena · International Journal of Innovative Science and Research Technology (IJISRT)
Open access |
29 May 2024 |
4 |
| 46 |
Roadways Wind Turbine Technology
Raja Kumar, Pankaj Kumar, Pritam meena et al. · Journal of Nonlinear Analysis and Optimization Theory & Applications (JNAO)
Open access |
2023 |
4 |
| 47 |
Caste, gender, and labour: A case study of dalit women domestic workers
Aishwarya Arora · International Journal of Political Science and Governance
Open access |
Jul 2023 |
4 |
| 48 |
Quantitative Analysis of Document Stored Databases
Pradeep Soni, Narendra Singh Yadav · International Journal of Computer Applications
Open access |
19 May 2015 |
4 |
| 49 |
Physico-Chemical Analysis of Sugar Mill Effluent of Kabirdham (C.G.)
Chhaya Bhatt, Rashmi Verma · International Journal of Scientific Engineering and Research
Open access |
27 Oct 2016 |
3 |
| 50 |
No idle flow shop scheduling models with separated set-up times and concept of job weightage to optimize rental cost of machines
Shakuntala Singla, Harshleen Kaur, Deepak Gupta et al. · Journal of Project Management
Open access |
2024 |
3 |