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Fibronectin Binding Protein and Host Cell Tyrosine Kinase Are Required for Internalization of Staphylococcus aureus by Epithelial Cells
Katarzyna Dziewanowska, Joseph M. Patti, Claudia F. Deobald et al. · Infection and Immunity
Open access |
Sep 1999 |
296 |
| 2 |
Advances in fluorescence derivatization methods for high-performance liquid chromatographic analysis of glycoprotein carbohydrates
Kalyan R. Anumula · Analytical Biochemistry
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18 Oct 2005 |
256 |
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Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities
Donald C. Porter et al. · Proceedings of the National Academy of Sciences
Open access |
6 Aug 2012 |
178 |
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Characterization of a Protective Monoclonal AntibodyRecognizing Staphylococcus aureus MSCRAMM ProteinClumping FactorA
Andrea E. Hall, Paul J. Domanski, Pratiksha R. Patel et al. · Infection and Immunity
Open access |
25 Nov 2003 |
147 |
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CDK8/19 Mediator kinases potentiate induction of transcription by NFκB
Mengqian Chen, Jiaxin Liang, Hao Ji et al. · Proceedings of the National Academy of Sciences
Open access |
30 Aug 2017 |
145 |
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Staphylococcal Fibronectin Binding Protein Interacts with Heat Shock Protein 60 and Integrins: Role in Internalization by Epithelial Cells
Katarzyna Dziewanowska, Andrew R. Carson, Joseph M. Patti et al. · Infection and Immunity
Open access |
Nov 2000 |
140 |
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Wnt/β-Catenin activation promotes prostate tumor progression in a mouse model
Xiuping Yu, Y Wang, David J. DeGraff et al. · Oncogene
Open access |
13 Dec 2010 |
130 |
| 8 |
Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer
Eugenia V. Broude, Balázs Győrffy, Alexander A. Chumanevich et al. · Current Cancer Drug Targets
Open access |
30 Sep 2015 |
101 |
| 9 |
Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus
Christopher McGuigan, Karolina Madela, Mohamed Aljarah et al. · Bioorganic & Medicinal Chemistry Letters
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21 Jun 2010 |
99 |
| 10 |
A humanized monoclonal antibody targeting Staphylococcus aureus
Joseph M. Patti · Vaccine
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14 Sep 2004 |
84 |
| 11 |
INX-08189, a Phosphoramidate Prodrug of 6-O-Methyl-2′-C-Methyl Guanosine, Is a Potent Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic and Pharmacodynamic Properties
John H. Vernachio et al. · Antimicrobial Agents and Chemotherapy
Open access |
Mar 2011 |
84 |
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CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins
Mengqian Chen et al. · Nucleic Acids Research
Open access |
10 Jun 2023 |
76 |
| 13 |
Multicenter Study to Assess Safety and Efficacy of INH-A21, a Donor-Selected Human Staphylococcal Immunoglobulin, for Prevention of Nosocomial Infections in Very Low Birth Weight Infants
Barry T. Bloom, Robert L. Schelonka, Tom J. Kueser et al. · The Pediatric Infectious Disease Journal
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Oct 2005 |
66 |
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A Recombinant Clumping Factor A-Containing Vaccine Induces Functional Antibodies to Staphylococcus aureus That Are Not Observed after Natural Exposure
Julio C. Hawkins, Srinivas Kodali, Yury V. Matsuka et al. · Clinical and Vaccine Immunology
Open access |
16 Aug 2012 |
63 |
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Phosphoramidate ProTides of 2′- C -Methylguanosine as Highly Potent Inhibitors of Hepatitis C Virus. Study of Their in Vitro and in Vivo Properties
Christopher McGuigan et al. · Journal of Medicinal Chemistry
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8 Jun 2010 |
57 |
| 16 |
Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo
Xiaokai Ding, Amanda C. Sharko, Martina S.J. McDermott et al. · Proceedings of the National Academy of Sciences
Open access |
Aug 2022 |
56 |
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Phosphorodiamidates as a Promising New Phosphate Prodrug Motif for Antiviral Drug Discovery: Application to Anti-HCV Agents
Christopher McGuigan et al. · Journal of Medicinal Chemistry
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31 Oct 2011 |
54 |
| 18 |
A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics
Li Zhang, Chen Cheng, Jing Li et al. · Journal of Medicinal Chemistry
Open access |
3 Feb 2022 |
40 |
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Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides
Christopher McGuigan, Claire Bourdin, Marco Derudas et al. · European Journal of Medicinal Chemistry
Open access |
9 Oct 2013 |
33 |
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TP53 codon 72 polymorphism affects accumulation of mtDNA damage in human cells
Serena Altilia, Aurelia Santoro, Davide Malagoli et al. · Aging
Open access |
29 Jan 2012 |
30 |
| 21 |
VHL2C Phenotype in a German von Hippel-Lindau Family with ConcurrentVHLGermline Mutations P81S and L188V
Gregor Weirich, Bettina Klein, Thorsten Wöhl et al. · The Journal of Clinical Endocrinology & Metabolism
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Nov 2002 |
29 |
| 22 |
Mediator kinase inhibition reverses castration resistance of advanced prostate cancer
Jing Li et al. · Journal of Clinical Investigation
Open access |
28 Mar 2024 |
23 |
| 23 |
Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay
Jing Li, Hao Ji, Donald C. Porter et al. · Cells
Open access |
6 Oct 2019 |
23 |
| 24 |
Dual pro-drugs of 2′-C-methyl guanosine monophosphate as potent and selective inhibitors of hepatitis C virus
Christopher McGuigan, Karolina Madela, Mohamed Aljarah et al. · Bioorganic & Medicinal Chemistry Letters
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26 Jun 2011 |
23 |
| 25 |
Detection of morphine in urine based on a surface plasmon resonance imaging immunoassay
Haokun Ke, Xianchao Du, Ling Wang et al. · Analytical Methods
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2020 |
19 |
| 26 |
In Vivo Expression of a GST-Fusion Protein Mediates the Rapid Generation of Affinity Matured Monoclonal Antibodies Using DNA-Based Immunizations
Katherine E. Kilpatrick, Sandy Kerner, Eric P. Dixon et al. · Hybridoma and Hybridomics
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Aug 2002 |
15 |
| 27 |
Biotechnology in Commercial Mushroom Fermentation
T. E. Tautorus, P. M. Townsley · Nature Biotechnology
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Aug 1984 |
13 |
| 28 |
460 A STUDY OF THE SAFETY AND PHARMACOKINETICS OF SINGLE ASCENDING ORAL DOSES OF INX-08189, A NUCLEOTIDE POLYMERASE INHIBITOR, IN HEALTHY SUBJECTS
Joseph M. Patti, Mark Matson, Brian A. Boehlecke et al. · Journal of Hepatology
Open access |
Mar 2011 |
13 |
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Antibody response to the extracellular adherence protein (Eap) ofStaphylococcus aureusin healthy and infected individuals
Insa Joost, Susanne Jacob, Olaf Utermöhlen et al. · FEMS Immunology & Medical Microbiology
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20 Jan 2011 |
13 |
| 30 |
Mediator kinase inhibitors suppress triple-negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors
Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko et al. · Proceedings of the National Academy of Sciences
Open access |
14 Nov 2024 |
10 |
| 31 |
Monitoring Glycosylation of Therapeutic Glycoproteins for Consistency by HPLC Using Highly Fluorescent Anthranilic Acid (AA) Tag
Shirish T. Dhume, George N. Saddic, Kalyan R. Anumula · Humana Press eBooks
Book chapter |
29 Mar 2008 |
10 |
| 32 |
Will we ever see the approval of aStaphylococcus aureusvaccine?
Joseph M. Patti · Expert Review of Anti-infective Therapy
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Oct 2011 |
10 |
| 33 |
Carbohydrate Composition Analysis of Glycoproteins by HPLC Using Highly Fluorescent Anthranilic Acid (AA) Tag
George N. Saddic, Shirish T. Dhume, Kalyan R. Anumula · Humana Press eBooks
Book chapter |
29 Mar 2008 |
10 |
| 34 |
The autophilic anti-CD20 antibody DXL625 displays enhanced potency due to lipid raft-dependent induction of apoptosis
Marc G. Bingaman, Gargi Dan Basu, Tiana C. Golding et al. · Anti-Cancer Drugs
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23 Mar 2010 |
9 |
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Knockout of cyclin-dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice
Alexandra V. Bruter et al. · eLife
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May 2024 |
8 |
| 36 |
2′-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743
Christopher McGuigan, Marco Derudas, Maurizio Quintiliani et al. · Bioorganic & Medicinal Chemistry Letters
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5 Oct 2009 |
8 |
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970 PRECLINICAL CHARACTERIZATION OF ABT-072: A NOVEL NON-NUCLEOSIDE HCV POLYMERASE INHIBITOR
Renaud Wagner et al. · Journal of Hepatology
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Apr 2009 |
8 |
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Chronic thoracic pain after cardiac surgery: role of inflammation and biomechanical sternal stability
Jeko M. Madjarov, Michael G. Katz, Yoav Hadas et al. · Frontiers in Pain Research
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11 Aug 2023 |
7 |
| 39 |
Application of Electro-Activated Dissociation Fragmentation Technique to Identifying Glucuronidation and Oxidative Metabolism Sites of Vepdegestrant by Liquid Chromatography-High Resolution Mass Spectrometry
Yifei He, Pengyi Hou, Zhimin Long et al. · Drug Metabolism and Disposition
Open access |
3 Jun 2024 |
6 |
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Synthesis and evaluation against hepatitis C virus of 7-deaza analogues of 2′-C-methyl-6-O-methyl guanosine nucleoside and l-Alanine ester phosphoramidates
Claire Bourdin et al. · Bioorganic & Medicinal Chemistry Letters
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20 Dec 2012 |
6 |
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Immunotherapeutics for nosocomial infections
Joseph M. Patti · Expert Opinion on Investigational Drugs
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28 May 2004 |
5 |
| 42 |
CDK8/19 Inhibition Attenuates G1 Arrest Induced by BCR-ABL Antagonists and Accelerates Death of Chronic Myelogenous Leukemia Cells
Alvina I. Khamidullina, Margarita A. Yastrebova, Alexandra V. Bruter et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
25 Sep 2023 |
2 |
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CDK19 and CDK8 Mediator kinases drive androgen-independent in vivo growth of castration-resistant prostate cancer
Jing Li et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
11 Aug 2023 |
2 |
| 44 |
A Study of the Safety and Pharmacokinetics of Multiple Ascending Doses of FV-100 in Healthy Subjects
Mark Matson, Helen S. Pentikis, Brian A. Boehlecke et al. · Antiviral Research
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May 2009 |
2 |
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A Study of the Safety and Pharmacokinetics of Single and Multiple Doses of FV-100 in Subjects 65 Years and Over
Mark Matson, George J. Atiee, Helen S. Pentikis et al. · Antiviral Research
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May 2009 |
1 |
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CDK8/19 inhibition prevents adaptive resistance to CDK4/6 inhibitors in vitro and in vivo
Zachary T. Mack et al. · Cell Reports Medicine
Open access |
19 Aug 2026 |
0 |
| 47 |
Inhibition of CDK8 rescues impaired ischemic fracture healing
Christina A. Capobianco, Michelle J. Song, Easton C. Farrell et al. · npj Regenerative Medicine
Open access |
17 Jan 2026 |
0 |
| 48 |
PSRC Column–TSC Beam Composite System for the Hyundai Motor Group Innovation Center Singapore
Seung-Hwan Lee, Kwang-Won Jo, Kyong Min Ro et al. · Structural Engineering International
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24 Dec 2025 |
0 |
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Proteomic Analysis of Breast Cancer Subtypes Identifies Stromal Protein Profiles that Contribute to Aggressive Malignant Behavior
Jordan B. Burton, Philippe D. Gascard, Deng Pan et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
24 Jan 2025 |
0 |
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Metabolic gene therapy in a canine with pulmonary hypertension secondary to degenerative mitral valve disease
Michael G. Katz, Dan G. Ohad, P.J. de Putter et al. · Frontiers in Veterinary Science
Open access |
23 Sep 2024 |
0 |