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Most cited papers from Senex Biotechnology (United States)

What are the most cited papers from Senex Biotechnology (United States)?

The most cited paper from Senex Biotechnology (United States) is "Fibronectin Binding Protein and Host Cell Tyrosine Kinase Are Required for Internalization of Staphylococcus aureus by Epithelial Cells" (Katarzyna Dziewanowska, Joseph M. Patti, Claudia F. Deobald et al., 1999), with 296 citations. Next come "Advances in fluorescence derivatization methods for high-performance liquid chromatographic analysis of glycoprotein carbohydrates" (256) and "Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities" (178).

Showing 50 of 55 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Fibronectin Binding Protein and Host Cell Tyrosine Kinase Are Required for Internalization of Staphylococcus aureus by Epithelial Cells Katarzyna Dziewanowska, Joseph M. Patti, Claudia F. Deobald et al. · Infection and Immunity Open access Sep 1999 296
2 Advances in fluorescence derivatization methods for high-performance liquid chromatographic analysis of glycoprotein carbohydrates Kalyan R. Anumula · Analytical Biochemistry 18 Oct 2005 256
3 Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities Donald C. Porter et al. · Proceedings of the National Academy of Sciences Open access 6 Aug 2012 178
4 Characterization of a Protective Monoclonal AntibodyRecognizing Staphylococcus aureus MSCRAMM ProteinClumping FactorA Andrea E. Hall, Paul J. Domanski, Pratiksha R. Patel et al. · Infection and Immunity Open access 25 Nov 2003 147
5 CDK8/19 Mediator kinases potentiate induction of transcription by NFκB Mengqian Chen, Jiaxin Liang, Hao Ji et al. · Proceedings of the National Academy of Sciences Open access 30 Aug 2017 145
6 Staphylococcal Fibronectin Binding Protein Interacts with Heat Shock Protein 60 and Integrins: Role in Internalization by Epithelial Cells Katarzyna Dziewanowska, Andrew R. Carson, Joseph M. Patti et al. · Infection and Immunity Open access Nov 2000 140
7 Wnt/β-Catenin activation promotes prostate tumor progression in a mouse model Xiuping Yu, Y Wang, David J. DeGraff et al. · Oncogene Open access 13 Dec 2010 130
8 Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer Eugenia V. Broude, Balázs Győrffy, Alexander A. Chumanevich et al. · Current Cancer Drug Targets Open access 30 Sep 2015 101
9 Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus Christopher McGuigan, Karolina Madela, Mohamed Aljarah et al. · Bioorganic & Medicinal Chemistry Letters 21 Jun 2010 99
10 A humanized monoclonal antibody targeting Staphylococcus aureus Joseph M. Patti · Vaccine 14 Sep 2004 84
11 INX-08189, a Phosphoramidate Prodrug of 6-O-Methyl-2′-C-Methyl Guanosine, Is a Potent Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic and Pharmacodynamic Properties John H. Vernachio et al. · Antimicrobial Agents and Chemotherapy Open access Mar 2011 84
12 CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins Mengqian Chen et al. · Nucleic Acids Research Open access 10 Jun 2023 76
13 Multicenter Study to Assess Safety and Efficacy of INH-A21, a Donor-Selected Human Staphylococcal Immunoglobulin, for Prevention of Nosocomial Infections in Very Low Birth Weight Infants Barry T. Bloom, Robert L. Schelonka, Tom J. Kueser et al. · The Pediatric Infectious Disease Journal Oct 2005 66
14 A Recombinant Clumping Factor A-Containing Vaccine Induces Functional Antibodies to Staphylococcus aureus That Are Not Observed after Natural Exposure Julio C. Hawkins, Srinivas Kodali, Yury V. Matsuka et al. · Clinical and Vaccine Immunology Open access 16 Aug 2012 63
15 Phosphoramidate ProTides of 2′- C -Methylguanosine as Highly Potent Inhibitors of Hepatitis C Virus. Study of Their in Vitro and in Vivo Properties Christopher McGuigan et al. · Journal of Medicinal Chemistry 8 Jun 2010 57
16 Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo Xiaokai Ding, Amanda C. Sharko, Martina S.J. McDermott et al. · Proceedings of the National Academy of Sciences Open access Aug 2022 56
17 Phosphorodiamidates as a Promising New Phosphate Prodrug Motif for Antiviral Drug Discovery: Application to Anti-HCV Agents Christopher McGuigan et al. · Journal of Medicinal Chemistry 31 Oct 2011 54
18 A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics Li Zhang, Chen Cheng, Jing Li et al. · Journal of Medicinal Chemistry Open access 3 Feb 2022 40
19 Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides Christopher McGuigan, Claire Bourdin, Marco Derudas et al. · European Journal of Medicinal Chemistry Open access 9 Oct 2013 33
20 TP53 codon 72 polymorphism affects accumulation of mtDNA damage in human cells Serena Altilia, Aurelia Santoro, Davide Malagoli et al. · Aging Open access 29 Jan 2012 30
21 VHL2C Phenotype in a German von Hippel-Lindau Family with ConcurrentVHLGermline Mutations P81S and L188V Gregor Weirich, Bettina Klein, Thorsten Wöhl et al. · The Journal of Clinical Endocrinology & Metabolism Nov 2002 29
22 Mediator kinase inhibition reverses castration resistance of advanced prostate cancer Jing Li et al. · Journal of Clinical Investigation Open access 28 Mar 2024 23
23 Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay Jing Li, Hao Ji, Donald C. Porter et al. · Cells Open access 6 Oct 2019 23
24 Dual pro-drugs of 2′-C-methyl guanosine monophosphate as potent and selective inhibitors of hepatitis C virus Christopher McGuigan, Karolina Madela, Mohamed Aljarah et al. · Bioorganic & Medicinal Chemistry Letters 26 Jun 2011 23
25 Detection of morphine in urine based on a surface plasmon resonance imaging immunoassay Haokun Ke, Xianchao Du, Ling Wang et al. · Analytical Methods 2020 19
26 In Vivo Expression of a GST-Fusion Protein Mediates the Rapid Generation of Affinity Matured Monoclonal Antibodies Using DNA-Based Immunizations Katherine E. Kilpatrick, Sandy Kerner, Eric P. Dixon et al. · Hybridoma and Hybridomics Aug 2002 15
27 Biotechnology in Commercial Mushroom Fermentation T. E. Tautorus, P. M. Townsley · Nature Biotechnology Aug 1984 13
28 460 A STUDY OF THE SAFETY AND PHARMACOKINETICS OF SINGLE ASCENDING ORAL DOSES OF INX-08189, A NUCLEOTIDE POLYMERASE INHIBITOR, IN HEALTHY SUBJECTS Joseph M. Patti, Mark Matson, Brian A. Boehlecke et al. · Journal of Hepatology Open access Mar 2011 13
29 Antibody response to the extracellular adherence protein (Eap) ofStaphylococcus aureusin healthy and infected individuals Insa Joost, Susanne Jacob, Olaf Utermöhlen et al. · FEMS Immunology & Medical Microbiology Open access 20 Jan 2011 13
30 Mediator kinase inhibitors suppress triple-negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko et al. · Proceedings of the National Academy of Sciences Open access 14 Nov 2024 10
31 Monitoring Glycosylation of Therapeutic Glycoproteins for Consistency by HPLC Using Highly Fluorescent Anthranilic Acid (AA) Tag Shirish T. Dhume, George N. Saddic, Kalyan R. Anumula · Humana Press eBooks Book chapter 29 Mar 2008 10
32 Will we ever see the approval of aStaphylococcus aureusvaccine? Joseph M. Patti · Expert Review of Anti-infective Therapy Oct 2011 10
33 Carbohydrate Composition Analysis of Glycoproteins by HPLC Using Highly Fluorescent Anthranilic Acid (AA) Tag George N. Saddic, Shirish T. Dhume, Kalyan R. Anumula · Humana Press eBooks Book chapter 29 Mar 2008 10
34 The autophilic anti-CD20 antibody DXL625 displays enhanced potency due to lipid raft-dependent induction of apoptosis Marc G. Bingaman, Gargi Dan Basu, Tiana C. Golding et al. · Anti-Cancer Drugs 23 Mar 2010 9
35 Knockout of cyclin-dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice Alexandra V. Bruter et al. · eLife Open access May 2024 8
36 2′-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743 Christopher McGuigan, Marco Derudas, Maurizio Quintiliani et al. · Bioorganic & Medicinal Chemistry Letters Open access 5 Oct 2009 8
37 970 PRECLINICAL CHARACTERIZATION OF ABT-072: A NOVEL NON-NUCLEOSIDE HCV POLYMERASE INHIBITOR Renaud Wagner et al. · Journal of Hepatology Open access Apr 2009 8
38 Chronic thoracic pain after cardiac surgery: role of inflammation and biomechanical sternal stability Jeko M. Madjarov, Michael G. Katz, Yoav Hadas et al. · Frontiers in Pain Research Open access 11 Aug 2023 7
39 Application of Electro-Activated Dissociation Fragmentation Technique to Identifying Glucuronidation and Oxidative Metabolism Sites of Vepdegestrant by Liquid Chromatography-High Resolution Mass Spectrometry Yifei He, Pengyi Hou, Zhimin Long et al. · Drug Metabolism and Disposition Open access 3 Jun 2024 6
40 Synthesis and evaluation against hepatitis C virus of 7-deaza analogues of 2′-C-methyl-6-O-methyl guanosine nucleoside and l-Alanine ester phosphoramidates Claire Bourdin et al. · Bioorganic & Medicinal Chemistry Letters 20 Dec 2012 6
41 Immunotherapeutics for nosocomial infections Joseph M. Patti · Expert Opinion on Investigational Drugs 28 May 2004 5
42 CDK8/19 Inhibition Attenuates G1 Arrest Induced by BCR-ABL Antagonists and Accelerates Death of Chronic Myelogenous Leukemia Cells Alvina I. Khamidullina, Margarita A. Yastrebova, Alexandra V. Bruter et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 25 Sep 2023 2
43 CDK19 and CDK8 Mediator kinases drive androgen-independent in vivo growth of castration-resistant prostate cancer Jing Li et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 11 Aug 2023 2
44 A Study of the Safety and Pharmacokinetics of Multiple Ascending Doses of FV-100 in Healthy Subjects Mark Matson, Helen S. Pentikis, Brian A. Boehlecke et al. · Antiviral Research May 2009 2
45 A Study of the Safety and Pharmacokinetics of Single and Multiple Doses of FV-100 in Subjects 65 Years and Over Mark Matson, George J. Atiee, Helen S. Pentikis et al. · Antiviral Research May 2009 1
46 CDK8/19 inhibition prevents adaptive resistance to CDK4/6 inhibitors in vitro and in vivo Zachary T. Mack et al. · Cell Reports Medicine Open access 19 Aug 2026 0
47 Inhibition of CDK8 rescues impaired ischemic fracture healing Christina A. Capobianco, Michelle J. Song, Easton C. Farrell et al. · npj Regenerative Medicine Open access 17 Jan 2026 0
48 PSRC Column–TSC Beam Composite System for the Hyundai Motor Group Innovation Center Singapore Seung-Hwan Lee, Kwang-Won Jo, Kyong Min Ro et al. · Structural Engineering International 24 Dec 2025 0
49 Proteomic Analysis of Breast Cancer Subtypes Identifies Stromal Protein Profiles that Contribute to Aggressive Malignant Behavior Jordan B. Burton, Philippe D. Gascard, Deng Pan et al. · bioRxiv (Cold Spring Harbor Laboratory) PreprintOpen access 24 Jan 2025 0
50 Metabolic gene therapy in a canine with pulmonary hypertension secondary to degenerative mitral valve disease Michael G. Katz, Dan G. Ohad, P.J. de Putter et al. · Frontiers in Veterinary Science Open access 23 Sep 2024 0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.