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Most cited papers from SENS Research Foundation

What are the most cited papers from SENS Research Foundation?

The most cited paper from SENS Research Foundation is "Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype" (Christopher D. Wiley, Michael C. Velarde, Pacôme Lecot et al., 2015), with 1,273 citations. Next come "Role of immune cells in the removal of deleterious senescent cells" (360) and "A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood" (305).

Showing 50 of 51 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype Christopher D. Wiley, Michael C. Velarde, Pacôme Lecot et al. · Cell Metabolism Open access 16 Dec 2015 1,273
2 Role of immune cells in the removal of deleterious senescent cells Abhijit Kale, Amit Kumar Sharma, Alexandra Stolzing et al. · Immunity & Ageing Open access 3 Jun 2020 360
3 A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood Justin Rebo, Melod Mehdipour, Ranveer Gathwala et al. · Nature Communications Open access 22 Nov 2016 305
4 Aging of the Immune System: Focus on Natural Killer Cells Phenotype and Functions Ashley Brauning, Michael J. Rae, Gina Zhu et al. · Cells Open access 17 Mar 2022 208
5 Dissecting primary and secondary senescence to enable new senotherapeutic strategies Tesfahun Dessale Admasu, Michael J. Rae, Alexandra Stolzing · Ageing Research Reviews ReviewOpen access 21 Jul 2021 97
6 ARDD 2020: from aging mechanisms to interventions Garik V. Mkrtchyan et al. · Aging Open access 30 Dec 2020 57
7 Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant Amutha Boominathan, Shon Vanhoozer, Nathan Basisty et al. · Nucleic Acids Research Open access 4 Sep 2016 51
8 Selective ablation of primary and paracrine senescent cells by targeting iron dyshomeostasis Tesfahun Dessale Admasu, Kristie Kim, Michael J. Rae et al. · Cell Reports Open access Feb 2023 49
9 Toward a Unified Theory of Aging and Regeneration Michael D. West, Hal Sternberg, Ivan Labat et al. · Regenerative Medicine Open access 28 Aug 2019 47
10 Strategies for Engineered Negligible Senescence Ben Zealley, Aubrey D.N.J. de Grey · Gerontology Oct 2012 45
11 Latest advances in aging research and drug discovery Daniela Bakula et al. · Aging Open access 21 Nov 2019 28
12 Do We Have Genes that Exist to Hasten Aging? New Data, New Arguments, But the Answer is Still No Aubrey D.N.J. de Grey · Current Aging Science 5 Jun 2015 28
13 Innovating Aging: Promises and Pitfalls on the Road to Life Extension Jan Vijg, Aubrey D.N.J. de Grey · Gerontology Open access 2014 27
14 Musashi expression in intestinal stem cells attenuates radiation-induced decline in intestinal permeability and survival in Drosophila Amit Sharma, Kazutaka Akagi, Blaine Pattavina et al. · Scientific Reports Open access 5 Nov 2020 25
15 Cyclodextrin dimers: A versatile approach to optimizing encapsulation and their application to therapeutic extraction of toxic oxysterols Amelia M. Anderson, Tamari Kirtadze, Milo Malanga et al. · International Journal of Pharmaceutics Open access 8 Apr 2021 23
16 Medical Bioremediation: A Concept Moving Toward Reality John Schloendorn, Tim Webb, Kent Kemmish et al. · Rejuvenation Research Dec 2009 23
17 Cryopreservation of Mesenchymal Stem Cells Using Medical Grade Ice Nucleation Inducer Nicholas Martin Wragg, Dimitris Tampakis, Alexandra Stolzing · International Journal of Molecular Sciences Open access 13 Nov 2020 21
18 Codon optimization is an essential parameter for the efficient allotopic expression of mtDNA genes Caitlin J. Lewis, Bhavna Dixit, Elizabeth Batiuk et al. · Redox Biology Open access 11 Jan 2020 21
19 Efficient and safe correction of hemophilia A by lentiviral vector-transduced BOECs in an implantable device Cristina Olgasi, Chiara Borsotti, Simone Merlin et al. · Molecular Therapy — Methods & Clinical Development Open access 3 Nov 2021 20
20 Rapid enrichment of mitochondria from mammalian cell cultures using digitonin Bhavna Dixit, Shon Vanhoozer, Nana Abena Anti et al. · MethodsX Open access 23 Dec 2020 18
21 The B612 Foundation Sentinel Space Telescope Edward T. Lu, Harold J. Reitsema, John R. Troeltzsch et al. · New Space 22 Jan 2013 13
22 The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics Sanjana Saravanan, Caitlin J. Lewis, Bhavna Dixit et al. · Biomedicines Open access 18 Feb 2022 12
23 Clonal derivation of white and brown adipocyte progenitor cell lines from human pluripotent stem cells Michael D. West, Ching-Fang Chang, Dana Larocca et al. · Stem Cell Research & Therapy Open access 8 Jan 2019 12
24 A Quantitative Assessment of Factors Affecting the Technological Development and Adoption of Companion Diagnostics Dee Luo, James Andrew Buchan Smith, Nick A. Meadows et al. · Frontiers in Genetics Open access 28 Jan 2016 12
25 Whole-Animal Senescent Cytotoxic T Cell Removal Using Antibodies Linked to Magnetic Nanoparticles Justin Rebo, Keith Causey, Ben Zealley et al. · Rejuvenation Research Apr 2010 11
26 A human neuron Alzheimer’s disease model reveals barriers to senolytic translatability Chaska C. Walton, Ellen Y. Wang, Suckwon Lee et al. · Alzheimer s Research & Therapy Open access 26 Jul 2025 9
27 A Divide-and-Conquer Assault on Aging: Mainstream at Last Aubrey D.N.J. de Grey · Rejuvenation Research 12 Jul 2013 8
28 Mitochondria-Targeted Catalase Does Not Suppress Development of Cellular Senescence during Aging Bronwyn A. Mogck, Samantha T. Jezak, Christopher D. Wiley · Biomedicines Open access 10 Feb 2024 7
29 A small-molecule Psora-4 acts as a caloric restriction mimetic to promote longevity in C. elegans Tesfahun Dessale Admasu, Diogo Barardo, Li Fang Ng et al. · GeroScience Open access 14 May 2021 7
30 Zeno’s Paradox and the Faith that Technological Game-Changers Are Impossible Aubrey D.N.J. de Grey · Gerontology 15 Aug 2012 7
31 Enhanced co-culture and enrichment of human natural killer cells for the selective clearance of senescent cells Kristie Kim, Tesfahun Dessale Admasu, Alexandra Stolzing et al. · Aging Open access 4 Mar 2022 6
32 Exogenous expression of ATP8, a mitochondrial encoded protein, from the nucleus in vivo David V Begelman, Bhavna Dixit, Carly Truong et al. · Molecular Therapy — Methods & Clinical Development Open access 6 Nov 2024 5
33 Programs, Hyperfunction, and Damage: Why Definitions and Logic Matter So Much in Biogerontology Aubrey D.N.J. de Grey · Rejuvenation Research 31 Mar 2021 5
34 21 st Century Cures Act: An Act of Cure or Diagnosis? David A. Brindley, Zeeshaan Arshad, Dee Luo et al. · Rejuvenation Research Open access Aug 2015 5
35 A systematic review of lifespan studies in rodents using stem cell transplantations Oliver G. Frost, Pranav Ramkilawan, Abdelhadi Rebbaa et al. · Ageing Research Reviews ReviewOpen access 6 Apr 2024 4
36 The Practicality or Otherwise of Biomedical Rejuvenation Therapies: A Response to Kyriazis Aubrey D.N.J. de Grey · Rejuvenation Research 29 Jul 2014 4
37 In Silico Approaches and the Role of Ontologies in Aging Research Georg Fuellen, Melanie Boerries, Hauke S. Busch et al. · Rejuvenation Research Open access 4 Nov 2013 4
38 The coming of age of AGE Aubrey D.N.J. de Grey · GeroScience Open access 27 Nov 2020 2
39 Aging Is No Longer a “First-World Problem” Aubrey D.N.J. de Grey · Rejuvenation Research Dec 2015 2
40 The Rational Imperative to Aim High Aubrey D.N.J. de Grey · Rejuvenation Research Oct 2014 2
41 Inhibition of the metalloprotease ADAM19 as a novel senomorphic strategy to ameliorate gut permeability and senescence markers by modulating senescence-associated secretory phenotype (SASP) Sudipta Bar, Tyler A. U. Hilsabeck, Blaine Pattavina et al. · Aging Open access 20 Mar 2025 1
42 Cyclodextrin dimers: A pharmaceutical engineering approach to the therapeutic extraction of toxic oxysterols Matthew S. O’Connor, Daniel M. Clemens, Ann L. Anderson et al. · Atherosclerosis Aug 2021 1
43 To Age, or Not to Age: That Is the Question Maria Entraigues Abramson Book chapter 2019 1
44 Cancers co-opt cohabitants’ catabolism Ben Zealley, Aubrey D.N.J. de Grey · Cell Cycle Open access 11 Jun 2012 1
45 A Leader Who Leads by Example-Again Aubrey D.N.J. de Grey · Rejuvenation Research 28 May 2021 0
46 Review of Replacing Aging by Jean M. Hébert Aubrey D.N.J. de Grey · Rejuvenation Research Dec 2020 0
47 Cherish Your Exceptions, But Also Your Doubts Aubrey D.N.J. de Grey · Rejuvenation Research Open access 30 Jan 2019 0
48 Response to Milholland et al. (Rejuvenation Res. 2017;20:437–440) Aubrey D.N.J. de Grey · Rejuvenation Research Oct 2017 0
49 Mucolipidosis Type IV Ehud Goldin · Elsevier eBooks Book chapter 2015 0
50 Rescue of mitochondrial mutations via improved allotopic expression Amutha Boominathan, Kathleen Powers, Shon Vanhoozer et al. · Mitochondrion Sep 2015 0

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.