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21 May 2023 |
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15 Oct 2021 |
818 |
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Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation
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16 Dec 2019 |
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650 |
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Effect of heavy metal stress on antioxidative enzymes and lipid peroxidation in leaves and roots of two mangrove plant seedlings (Kandelia candel and Bruguiera gymnorrhiza)
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4 Sep 2023 |
645 |
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AlphaFold2 and its applications in the fields of biology and medicine
Zhenyu Yang, Xiaoxi Zeng, Yi Chen Zhao et al. · Signal Transduction and Targeted Therapy
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14 Mar 2023 |
604 |
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Overcoming cancer therapeutic bottleneck by drug repurposing
Zhe Zhang, Li Zhou, Na Xie et al. · Signal Transduction and Targeted Therapy
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2 Jul 2020 |
523 |
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Temporal single-cell tracing reveals clonal revival and expansion of precursor exhausted T cells during anti-PD-1 therapy in lung cancer
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23 Dec 2021 |
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Immune phenotypic linkage between colorectal cancer and liver metastasis
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17 Mar 2022 |
486 |
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MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters
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21 Oct 2022 |
480 |
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A pan-cancer single-cell panorama of human natural killer cells
Fei Tang, Jinhu Li, Lu Qi et al. · Cell
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21 Aug 2023 |
466 |
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Enhanced sampling in molecular dynamics
Yi Yang, Qiang Shao, Jun Zhang et al. · The Journal of Chemical Physics
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16 Aug 2019 |
441 |
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Supramolecular cancer nanotheranostics
Jiong Zhou, Lang Rao, Guocan Yu et al. · Chemical Society Reviews
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2021 |
416 |
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Insights Gained from Single-Cell Analysis of Immune Cells in the Tumor Microenvironment
Xianwen Ren, Lei Zhang, Yuanyuan Zhang et al. · Annual Review of Immunology
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26 Feb 2021 |
390 |
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The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy
Li Guo, Yuan Tian, Wei‐Guo Zhu · Frontiers in Cell and Developmental Biology
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29 Sep 2020 |
370 |
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Enhanced receptor binding of SARS-CoV-2 through networks of hydrogen-bonding and hydrophobic interactions
Yingjie Wang, Meiyi Liu, Jiali Gao · Proceedings of the National Academy of Sciences
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5 Jun 2020 |
365 |
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Biomedical Micro‐/Nanomotors: From Overcoming Biological Barriers to In Vivo Imaging
Changyong Gao, Yong Wang, Zihan Ye et al. · Advanced Materials
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24 Jun 2020 |
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Single-cell Stereo-seq reveals induced progenitor cells involved in axolotl brain regeneration
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Identification of differential RNA modifications from nanopore direct RNA sequencing with xPore
Ploy N. Pratanwanich, Fei Yao, Ying Chen et al. · Nature Biotechnology
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19 Jul 2021 |
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Engineering polyphenols with biological functions via polyphenol-protein interactions as additives for functional foods
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15 Feb 2021 |
323 |
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Extracellular vesicles: a rising star for therapeutics and drug delivery
Shuang Du, Yucheng Guan, Aihua Xie et al. · Journal of Nanobiotechnology
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20 Jul 2023 |
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Detection of m6A from direct RNA sequencing using a multiple instance learning framework
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10 Nov 2022 |
308 |
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Covalently Engineered Nanobody Chimeras for Targeted Membrane Protein Degradation
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294 |
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DFT exchange: sharing perspectives on the workhorse of quantum chemistry and materials science
Andrew M. Teale et al. · Physical Chemistry Chemical Physics
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2022 |
287 |
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Cross-tissue human fibroblast atlas reveals myofibroblast subtypes with distinct roles in immune modulation
Yang Gao, Jianan Li, Wenfeng Cheng et al. · Cancer Cell
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19 Sep 2024 |
283 |
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Ecological responses, adaptation and mechanisms of mangrove wetland ecosystem to global climate change and anthropogenic activities
You‐Shao Wang, Ji‐Dong Gu · International Biodeterioration & Biodegradation
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272 |
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Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species
Ruoke Wang, Qi Zhang, Jiwan Ge et al. · Immunity
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8 Jun 2021 |
264 |
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Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy
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256 |
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Harnessing Nanomaterials for Cancer Sonodynamic Immunotherapy
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239 |
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Pushing the frontiers: tools for monitoring neurotransmitters and neuromodulators
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31 Mar 2022 |
236 |
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Hierarchical graph learning for protein–protein interaction
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25 Feb 2023 |
234 |
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Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition
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228 |
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Cell transcriptomic atlas of the non-human primate Macaca fascicularis
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Structural and mechanistic insights into fungal β-1,3-glucan synthase FKS1
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22 Mar 2023 |
222 |
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Cold-chain food contamination as the possible origin of COVID-19 resurgence in Beijing
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Characterization and heterologous reconstitution of Taxus biosynthetic enzymes leading to baccatin III
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Surface hydroxide promotes CO2 electrolysis to ethylene in acidic conditions
Yufei Cao, Chen Zhu, Peihao Li et al. · Nature Communications
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25 Apr 2023 |
213 |
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Pan-cancer single-cell dissection reveals phenotypically distinct B cell subtypes
Yang Yu, Xueyan Chen, Jieying Pan et al. · Cell
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23 Jul 2024 |
208 |
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Structure-aware protein–protein interaction site prediction using deep graph convolutional network
Qianmu Yuan, Jianwen Chen, Huiying Zhao et al. · Bioinformatics
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8 Sep 2021 |
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Designing nanotheranostics with machine learning
Lang Rao, Yuan Yuan, Xi Shen et al. · Nature Nanotechnology
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Single-cell RNA sequencing reveals intrahepatic and peripheral immune characteristics related to disease phases in HBV-infected patients
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31 Mar 2022 |
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Integrated multi-omics profiling yields a clinically relevant molecular classification for esophageal squamous cell carcinoma
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29 Dec 2022 |
186 |
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A body map of somatic mutagenesis in morphologically normal human tissues
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25 Aug 2021 |
186 |