| 1 |
Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing
Raymond R. Tice, Eva Agurell, Diana Anderson et al. · Environmental and Molecular Mutagenesis
|
6 Jun 2000 |
4,883 |
| 2 |
High-performance liquid chromatography of reducing carbohydrates as strongly ultraviolet-absorbing and electrochemically sensitive 1-phenyl-3-methyl5-pyrazolone derivatives
Susumu Honda, Eiko Akao, Shigeo Suzuki et al. · Analytical Biochemistry
|
Aug 1989 |
666 |
| 3 |
Arbutin: mechanism of its depigmenting action in human melanocyte culture.
Kazuhisa Maeda, Mitsunori Fukuda · Journal of Pharmacology and Experimental Therapeutics
|
Feb 1996 |
532 |
| 4 |
Control of murine hair follicle regression (catagen) by TGF‐β1 in vivo
Kerstin Foitzik, G Lindner, Sven Mueller‐Roever et al. · The FASEB Journal
|
Apr 2000 |
384 |
| 5 |
Development of an in vitro skin sensitization test using human cell lines: The human Cell Line Activation Test (h-CLAT)
Takao Ashikaga, Yukiko Yoshida, Morihiko Hirota et al. · Toxicology in Vitro
|
29 Nov 2005 |
344 |
| 6 |
Molecular Control of Epithelial–Mesenchymal Interactions During Hair Follicle Cycling
Vladimir A. Botchkarev, Jiro Kishimoto · Journal of Investigative Dermatology Symposium Proceedings
Conference paperOpen access |
Jun 2003 |
335 |
| 7 |
Possible Involvement of Gelatinases in Basement Membrane Damage and Wrinkle Formation in Chronically Ultraviolet B-exposed Hairless Mouse
Shinji Inomata, Keiko Takada, Makoto Tsunenaga et al. · Journal of Investigative Dermatology
Open access |
2003 |
283 |
| 8 |
Functional Vanilloid Receptors in Cultured Normal Human Epidermal Keratinocytes
Kaori Inoue, Kaori Inoue, Schuichi Koizumi et al. · Biochemical and Biophysical Research Communications
|
Feb 2002 |
278 |
| 9 |
Kinetic study of quenching reaction of singlet oxygen and scavenging reaction of free radical by squalene in n-butanol
Yoshiyuki Kohno, Yoshifumi Egawa, Shingo Itoh et al. · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism
|
Apr 1995 |
275 |
| 10 |
2-Nonenal Newly Found in Human Body Odor Tends to Increase with Aging
Shinichiro Haze, Yoko Gozu, Shôji Nakamura et al. · Journal of Investigative Dermatology
Open access |
Apr 2001 |
270 |
| 11 |
The Human Skin Barrier Is Organized as Stacked Bilayers of Fully Extended Ceramides with Cholesterol Molecules Associated with the Ceramide Sphingoid Moiety
Ichiro Iwai, Hong‐Mei Han, Lianne den Hollander et al. · Journal of Investigative Dermatology
Open access |
26 Apr 2012 |
243 |
| 12 |
Ca2+ waves in keratinocytes are transmitted to sensory neurons: the involvement of extracellular ATP and P2Y2 receptor activation
Schuichi Koizumi, Kayoko Fujishita, Kaori Inoue et al. · Biochemical Journal
Open access |
Jun 2004 |
239 |
| 13 |
Interplay between microbial d-amino acids and host d-amino acid oxidase modifies murine mucosal defence and gut microbiota
Jumpei Sasabe, Yurika Miyoshi, Seth Rakoff-Nahoum et al. · Nature Microbiology
Open access |
25 Jul 2016 |
234 |
| 14 |
Exposure to a Dry Environment Enhances Epidermal Permeability Barrier Function
Mitsuhiro Denda, Junko Sato, Yoshiko Murakami Masuda et al. · Journal of Investigative Dermatology
Open access |
Nov 1998 |
234 |
| 15 |
Comparison of the depth profiles of water and water-binding substances in the stratum corneum determined in vivo by Raman spectroscopy between the cheek and volar forearm skin: effects of age, seasonal changes and artificial forced hydration
Mariko Egawa, Hachiro Tagami · British Journal of Dermatology
|
28 Nov 2007 |
230 |
| 16 |
TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding
Masakiyo Sakaguchi, Hitoshi Murata, Ken-ichi Yamamoto et al. · PLoS ONE
Open access |
Aug 2011 |
230 |
| 17 |
Immunoreactivity of VR1 on Epidermal Keratinocyte of Human Skin
Mitsuhiro Denda, Shigeyoshi Fuziwara, Kaori Inoue et al. · Biochemical and Biophysical Research Communications
|
Aug 2001 |
228 |
| 18 |
Effects of Citrus Fragrance on Immune Function and Depressive States
Teruhisa Komori, Ryoichi Fujiwara, Masahiro Tanida et al. · NeuroImmunoModulation
|
20 Nov 1995 |
227 |
| 19 |
Role of TGF-β2 in the human hair cycle
Toshihiko Hibino, Toshio Nishiyama · Journal of Dermatological Science
|
3 Apr 2004 |
225 |
| 20 |
Chiral amino acid metabolomics for novel biomarker screening in the prognosis of chronic kidney disease
Tomonori Kimura, Kenji Hamase, Yurika Miyoshi et al. · Scientific Reports
Open access |
18 May 2016 |
224 |
| 21 |
Multidimensional LC Separations in Shotgun Proteomics
Akira Motoyama, John R. Yates · Analytical Chemistry
|
30 Sep 2008 |
224 |
| 22 |
Categorization of Chemicals According to Their Relative Human Skin Sensitizing Potency
David A. Basketter, Nathalie Alépée, Takao Ashikaga et al. · Dermatitis
|
Feb 2014 |
224 |
| 23 |
Melanocyte‐Stimulating Properties of Arachidonic Acid Metabolites: Possible Role in Postinflammatory Pigmentation
Yasushi Tomita, Kazuhisa Maeda, Hachiro Tagami · Pigment Cell Research
|
Nov 1992 |
222 |
| 24 |
Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT) II. An inter-laboratory study of the h-CLAT
H. Sakaguchi, Takao Ashikaga, Masaaki Miyazawa et al. · Toxicology in Vitro
|
8 Dec 2005 |
221 |
| 25 |
Modulations in Epidermal Calcium Regulate the Expression of Differentiation-Specific Markers
Peter M. Elias, Sung Ku Ahn, Mitsuhiro Denda et al. · Journal of Investigative Dermatology
Open access |
Nov 2002 |
216 |
| 26 |
Effects of Skin Surface Temperature on Epidermal Permeability Barrier Homeostasis
Mitsuhiro Denda, Takaaki Sokabe, Tomoko Fukumi‐Tominaga et al. · Journal of Investigative Dermatology
Open access |
26 Oct 2006 |
213 |
| 27 |
Neuropeptide Control Mechanisms in Cutaneous Biology: Physiological and Clinical Significance
Eva M.J. Peters, Marna Elise Ericson, Junichi Hosoi et al. · Journal of Investigative Dermatology
Open access |
15 Aug 2006 |
213 |
| 28 |
d -Amino acid oxidase controls motoneuron degeneration through d -serine
Jumpei Sasabe, Yurika Miyoshi, Masataka Suzuki et al. · Proceedings of the National Academy of Sciences
Open access |
27 Dec 2011 |
208 |
| 29 |
Non-animal methods to predict skin sensitization (II): an assessment of defined approaches
Nicole Kleinstreuer et al. · Critical Reviews in Toxicology
Open access |
23 Feb 2018 |
206 |
| 30 |
Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database
Sebastian Hoffmann et al. · Critical Reviews in Toxicology
Open access |
23 Feb 2018 |
188 |
| 31 |
Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc
Yongchan Lee, Pattama Wiriyasermkul, Chunhuan Jin et al. · Nature Structural & Molecular Biology
|
Jun 2019 |
183 |
| 32 |
Neutral Cysteine Protease Bleomycin Hydrolase Is Essential for the Breakdown of Deiminated Filaggrin into Amino Acids
Yayoi Kamata, Aya Taniguchi, Mami Yamamoto et al. · Journal of Biological Chemistry
Open access |
13 Mar 2009 |
173 |
| 33 |
Effects of Fragrance Inhalation on Sympathetic Activity in Normal Adults
Shinichiro Haze, Keiko Sakai, Yoko Gozu · The Japanese Journal of Pharmacology
Open access |
2002 |
171 |
| 34 |
Long-Term Culture of Mouse Vibrissal Dermal Papilla Cells and De Novo Hair Follicle Induction
Aki Osada, Tokuro Iwabuchi, Jiro Kishimoto et al. · Tissue Engineering
|
6 Mar 2007 |
171 |
| 35 |
Topical Simvastatin Accelerates Wound Healing in Diabetes by Enhancing Angiogenesis and Lymphangiogenesis
Jun Asai, Hideya Takenaka, Satoshi Hirakawa et al. · American Journal Of Pathology
Open access |
5 Nov 2012 |
169 |
| 36 |
Bayesian integrated testing strategy (ITS) for skin sensitization potency assessment: a decision support system for quantitative weight of evidence and adaptive testing strategy
Joanna S. Jaworska, Andreas Natsch, Cindy A. Ryan et al. · Archives of Toxicology
|
26 Nov 2015 |
167 |
| 37 |
Stress alters cutaneous permeability barrier homeostasis
Mitsuhiro Denda, Toru Tsuchiya, Peter M. Elias et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
|
Feb 2000 |
166 |
| 38 |
Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen
Tatsuya Hasegawa, Tomonori Oka, Heehwa G. Son et al. · Cell
Open access |
Mar 2023 |
163 |
| 39 |
Gut microbiota–derived D-serine protects against acute kidney injury
Yusuke Nakade et al. · JCI Insight
Open access |
17 Oct 2018 |
160 |
| 40 |
Determination of d-serine and d-alanine in the tissues and physiological fluids of mice with various d-amino-acid oxidase activities using two-dimensional high-performance liquid chromatography with fluorescence detection
Yurika Miyoshi, Kenji Hamase, Yosuke Tojo et al. · Journal of Chromatography B
|
24 Jun 2009 |
152 |
| 41 |
Topical trans-4-aminomethylcyclohexanecarboxylic acid prevents ultraviolet radiation-induced pigmentation
Kazuhisa Maeda, Masako Naganuma · Journal of Photochemistry and Photobiology B Biology
|
Dec 1998 |
149 |
| 42 |
Effect of exposure of human skin to a dry environment
Mariko Egawa, Motoki Oguri, Tomohiro Kuwahara et al. · Skin Research and Technology
|
Nov 2002 |
149 |
| 43 |
Primary structure of the Saccharomyces cerevisiae GAL7 gene
Tajima Masahiro, Yasuhisa Nogi, Toshio Fukasawa · Yeast
|
Sep 1985 |
146 |
| 44 |
Epidermal keratinocytes as the forefront of the sensory system
Mitsuhiro Denda, Masashi Nakatani, Kazuyuki Ikeyama et al. · Experimental Dermatology
|
6 Feb 2007 |
144 |
| 45 |
Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo andIn Vitro
Tsutomu Soma, Masashi Ogo, Jun‐ichi Suzuki et al. · Journal of Investigative Dermatology
Open access |
Dec 1998 |
143 |
| 46 |
Simultaneous determination of hydrophilic amino acid enantiomers in mammalian tissues and physiological fluids applying a fully automated micro-two-dimensional high-performance liquid chromatographic concept
Kenji Hamase, Yurika Miyoshi, Kyoko Ueno et al. · Journal of Chromatography A
|
7 Sep 2009 |
141 |
| 47 |
Involvement of Transforming Growth Factor-β2 in Catagen Induction During the Human Hair Cycle
Tsutomu Soma, Yumiko Tsuji, Toshihiko Hibino · Journal of Investigative Dermatology
Open access |
Jun 2002 |
140 |
| 48 |
Ultraviolet B irradiation of human skin induces an angiogenic switch that is mediated by upregulation of vascular endothelial growth factor and by downregulation of thrombospondin-1
Kimihiko Yano, Kotaro Kadoya, Kentaro Kajiya et al. · British Journal of Dermatology
|
2005 |
139 |
| 49 |
Systematic evaluation of non-animal test methods for skin sensitisation safety assessment
Kerstin Bianca Reisinger et al. · Toxicology in Vitro
Open access |
30 Oct 2014 |
135 |
| 50 |
Apelin Inhibits Diet-Induced Obesity by Enhancing Lymphatic and Blood Vessel Integrity
Mika Sawane, Kentaro Kajiya, Hiroyasu Kidoya et al. · Diabetes
Open access |
2 Feb 2013 |
133 |