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Most cited papers from Showa Pharmaceutical University

What are the most cited papers from Showa Pharmaceutical University?

The most cited paper from Showa Pharmaceutical University is "The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity" (Toshimasa Yamauchi et al., 2001), with 4,950 citations. Next come "Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling" (937) and "Isolation and Characterization of GBP28, a Novel Gelatin-Binding Protein Purified from Human Plasma" (913).

Showing 50 of 58 papers. Every paper with more than 173 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity Toshimasa Yamauchi et al. · Nature Medicine Aug 2001 4,950
2 Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling Tomoaki Ida, Tomohiro Sawa, Hideshi Ihara et al. · Proceedings of the National Academy of Sciences Open access 14 Apr 2014 937
3 Isolation and Characterization of GBP28, a Novel Gelatin-Binding Protein Purified from Human Plasma Yasuko Nakano, Takashi Tobe, N.-H. Choi-Miura et al. · The Journal of Biochemistry Oct 1996 913
4 LTRPC2 Ca2+-Permeable Channel Activated by Changes in Redox Status Confers Susceptibility to Cell Death Yuji Hara, Minoru Wakamori, Masakazu Ishii et al. · Molecular Cell Open access 2002 834
5 Current status of zirconia restoration Takashi Miyazaki, Takashi Nakamura, Hideo Matsumura et al. · Journal of Prosthodontic Research Open access Oct 2013 767
6 Phospholipase A2 enzymes Ichiro Kudo, Makoto Murakami · Prostaglandins & Other Lipid Mediators Aug 2002 754
7 Genetic Variation in the Gene Encoding Adiponectin Is Associated With an Increased Risk of Type 2 Diabetes in the Japanese Population Kazuo Hara et al. · Diabetes Feb 2002 706
8 Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α‐synuclein Pang‐Hsien Tu, James E. Galvin, Minami Baba et al. · Annals of Neurology Sep 1998 702
9 Nitric oxide activates TRP channels by cysteine S-nitrosylation Takashi Yoshida, Ryuji Inoue, Takashi Morii et al. · Nature Chemical Biology 24 Sep 2006 571
10 The Belle II Physics Book E Kou et al. · Progress of Theoretical and Experimental Physics Open access539 authors 26 Aug 2019 567
11 Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics Takaaki Akaike et al. · Nature Communications Open access 23 Oct 2017 557
12 Regulatory Functions of Phospholipase A2 Makoto Murakami, Yoshihito Nakatani, Gen‐ichi Atsumi et al. · Critical Reviews in Immunology 1997 548
13 Constitutive Phosphorylation of the Parkinson's Disease Associated α-Synuclein Masayasu Okochi, Jochen Walter, Akihiko Koyama et al. · Journal of Biological Chemistry Open access 2000 525
14 Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain–Barré syndrome Nobuhiro Yuki, Keiichiro Susuki, Michiaki Koga et al. · Proceedings of the National Academy of Sciences Open access 26 Jul 2004 501
15 Measurement of the τ Lepton Polarization and R ( D * ) in the Decay B ¯ → D * τ − ν ¯ τ S. Hirose et al. · Physical Review Letters Open access194 authors 26 May 2017 491
16 Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum high-density lipoprotein-cholesterol, independent of body mass index, in the Japanese population Yukihiro YAMAMOTO, Hiroshi Hirose, Ikuo Saito et al. · Clinical Science 3 Jul 2002 478
17 Molecular and Functional Characterization of a Novel Mouse Transient Receptor Potential Protein Homologue TRP7 Takaharu Okada, Ryuji Inoue, Kazuto Yamazaki et al. · Journal of Biological Chemistry Open access Sep 1999 462
18 Structural basis for the activation of PPARγ by oxidized fatty acids Toshimasa Itoh, Louise Fairall, Kush Amin et al. · Nature Structural & Molecular Biology Open access 17 Aug 2008 459
19 Role of human cytochrome P4502A6 in C-oxidation of nicotine. Masatoshi Nakajima, Takahiko Yamamoto, K Nunoya et al. · Drug Metabolism and Disposition Nov 1996 421
20 Gemfibrozil and Its Glucuronide Inhibit the Organic Anion Transporting Polypeptide 2 (OATP2/OATP1B1:SLC21A6)-Mediated Hepatic Uptake and CYP2C8-Mediated Metabolism of Cerivastatin: Analysis of the Mechanism of the Clinically Relevant Drug-Drug Interaction between Cerivastatin and Gemfibrozil Yoshihisa Shitara, Masaru Hirano, Hitoshi Sato et al. · Journal of Pharmacology and Experimental Therapeutics 16 Sep 2004 406
21 Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound Shigeki Kiyonaka et al. · Proceedings of the National Academy of Sciences Open access 16 Mar 2009 390
22 A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine Tadashi Miyasaka, Hiromichi Tanaka, Masanori Baba et al. · Journal of Medicinal Chemistry Open access Dec 1989 384
23 Recent advances in molecular biology and physiology of the prostaglandin E2-biosynthetic pathway Makoto Murakami, Ichiro Kudo · Progress in Lipid Research 16 Jul 2003 369
24 Measurement of the branching ratio of B ¯ 0 → D * + τ − ν ¯ τ relative to B ¯ 0 → D * + ℓ − ν ¯ ℓ decays with a semileptonic tagging method Y. Sato et al. · Physical review. D/Physical review. D. Open access182 authors 27 Oct 2016 362
25 Perilipins: a diversity of intracellular lipid droplet proteins Hiroyuki Itabe, Tomohiro Yamaguchi, Satomi Nimura et al. · Lipids in Health and Disease Open access 28 Apr 2017 360
26 Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population Genta Sawada et al. · Gastroenterology Open access 10 Feb 2016 345
27 A mitochondrial superoxide theory for oxidative stress diseases and aging Hiroko P. Indo, Hsiu‐Chuan Yen, Ikuo Nakanishi et al. · Journal of Clinical Biochemistry and Nutrition Open access 22 Dec 2014 337
28 Lepton-Flavor-Dependent Angular Analysis of B → K * ℓ + ℓ − S. Wehle et al. · Physical Review Letters Open access205 authors 13 Mar 2017 312
29 Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes. Masatoshi Nakajima, Takahiko Yamamoto, K Nunoya et al. · Journal of Pharmacology and Experimental Therapeutics May 1996 285
30 The Belle II Physics Book Zupanc, A. et al. · RWTH Publications (RWTH Aachen) Open access539 authors 2019 269
31 Isolation from Human Erythrocytes of a New Membrane Protein Which Inhibits the Formation of Complement Transmembrane Channels1 Yuji Sugita, Yasuko Nakano, Motowo Tomita · The Journal of Biochemistry Oct 1988 267
32 Comparison of Serum High–Molecular Weight (HMW) Adiponectin With Total Adiponectin Concentrations in Type 2 Diabetic Patients With Coronary Artery Disease Using a Novel Enzyme-Linked Immunosorbent Assay to Detect HMW Adiponectin Yoshimasa Aso, Ruriko Yamamoto, Sadao Wakabayashi et al. · Diabetes Open access 27 Jun 2006 264
33 The Clinical Pharmacokinetics of Escitalopram Niranjan Sathyanarayana Rao · Clinical Pharmacokinetics 2007 258
34 Bactericidal activity of Ag–zeolite mediated by reactive oxygen species under aerated conditions Yoshihiro H. Inoue, Masanobu Hoshino, Hiroo Takahashi et al. · Journal of Inorganic Biochemistry Sep 2002 257
35 Hypocholesterolemic and antioxidant effects of aqueous extracts from the dried calyx of Hibiscus sabdariffa L. in hypercholesterolemic rats Vilasinee Hirunpanich, Anocha Utaipat, Noppawan Phumala Morales et al. · Journal of Ethnopharmacology 18 Oct 2005 256
36 Synthesis of Pyrroles by Gold(I)-Catalyzed Amino−Claisen Rearrangement of N-Propargyl Enaminone Derivatives Akio Saito, Tomoyo Konishi, Yuji Hanzawa · Organic Letters 21 Dec 2009 252
37 Measurement of R ( D ) and R ( D * ) with a Semileptonic Tagging Method G. Caria et al. · Physical Review Letters Open access204 authors 24 Apr 2020 239
38 Measurement of the τ lepton polarization and R ( D * ) in the decay B ¯ → D * τ − ν ¯ τ with one-prong hadronic τ decays at Belle S. Hirose et al. · Physical review. D/Physical review. D. Open access184 authors 10 Jan 2018 233
39 Prostaglandin E synthase Makoto Murakami, Yoshihito Nakatani, Toshihiro Tanioka et al. · Prostaglandins & Other Lipid Mediators Aug 2002 231
40 TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α Anahita Hamidi, Jie Song, Noopur Thakur et al. · Science Signaling 4 Jul 2017 225
41 A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob Hiroyuki Mizuguchi, Noriko Koizumi, Tetsuji Hosono et al. · Gene Therapy May 2001 225
42 Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell deathin rats Sachiko Tanaka, Masatoshi Ide, Toshiomi Shibutani et al. · Journal of Neuroscience Research 2006 225
43 Stimulation of in vitro angiogenesis by hydrogen peroxide and the relation with Ets-1 in endothelial cells Masako Yasuda, Yumi Ohzeki, Shunichi Shimizu et al. · Life Sciences Dec 1998 220
44 Phenotypic Change from Transformed to Normal Induced by Benzoquinonoid Ansamycins Accompanies Inactivation of p60 src in Rat Kidney Cells Infected with Rous Sarcoma Virus Yoshimasa Uehara, Makoto Hori, TOMIO TAKEUCHI et al. · Molecular and Cellular Biology Open access Jun 1986 218
45 Mice Lacking Pin1 Develop Normally, but Are Defective in Entering Cell Cycle from G0 Arrest Fumihiro Fujimori, Katsuhiko Takahashi, Chiyoko Uchida et al. · Biochemical and Biophysical Research Communications Nov 1999 215
46 Chemie von a‐Aminonitrilen. Aldomerisierung von Glycolaldehyd‐phosphat zu racemischen Hexose‐2,4,6‐triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose‐2,4‐diphosphaten: rac‐Allose‐2,4,6‐triphosphat und rac‐Ribose‐2,4‐diphosphat sind die Reaktionshauptprodukte D Müller, Stefan Pitsch, Atsushi Kittaka et al. · Helvetica Chimica Acta Open access 8 Aug 1990 214
47 Relationship between health literacy, health information access, health behavior, and health status in Japanese people Machi Suka, Takeshi Odajima, Masako Okamoto et al. · Patient Education and Counseling 24 Feb 2015 214
48 The antibacterial effects of terpene alcohols on Staphylococcus aureus and their mode of action Yoshihiro H. Inoue, Akiko Shiraishi, Toshiko Hada et al. · FEMS Microbiology Letters Aug 2004 207
49 Loss of function of 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase 1 (HMG1) in Arabidopsis leads to dwarfing, early senescence and male sterility, and reduced sterol levels Masashi Suzuki, Yukiko Kamide, Noriko Nagata et al. · The Plant Journal 26 Jan 2004 207
50 Antibacterial Activity of Long-Chain Fatty Alcohols against Staphylococcus aureus Naoko Togashi, Akiko Shiraishi, Miki Nishizaka et al. · Molecules Open access 5 Feb 2007 202

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.