Most cited papers from Siena Biotech (Italy)
What are the most cited papers from Siena Biotech (Italy)?
The most cited paper from Siena Biotech (Italy) is "Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58" (Hervé Tettelin et al., 2000), with 1,105 citations. Next come "Target deconvolution strategies in drug discovery" (438) and "Induction of Dickkopf-1, a Negative Modulator of the Wnt Pathway, Is Associated with Neuronal Degeneration in Alzheimer's Brain" (401).
Showing 50 of 61 papers. Every paper with more than 44 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58 Hervé Tettelin et al. · Science | 10 Mar 2000 | 1,105 |
| 2 | Target deconvolution strategies in drug discovery Georg C. Terstappen, Christina Schlüpen, Roberto Raggiaschi et al. · Nature Reviews Drug Discovery | 5 Oct 2007 | 438 |
| 3 | Induction of Dickkopf-1, a Negative Modulator of the Wnt Pathway, Is Associated with Neuronal Degeneration in Alzheimer's Brain Andrea Caricasole, Agata Copani, Filippo Caraci et al. · Journal of Neuroscience | 30 Jun 2004 | 401 |
| 4 | BLUEPRINT to decode the epigenetic signature written in blood David J. Adams et al. · Nature Biotechnology | Mar 2012 | 384 |
| 5 | ATP extracellular concentrations are increased in the rat striatum during in vivo ischemia Alessia Melani, D. Turchi, Maria Giuliana Vannucchi et al. · Neurochemistry International | 19 Jul 2005 | 257 |
| 6 | Increased Dickkopf‐1 expression in transgenic mouse models of neurodegenerative disease Maria Cristina Rosi, Ilaria Luccarini, Cristina Grossi et al. · Journal of Neurochemistry | 29 Dec 2009 | 173 |
| 7 | An exploratory double‐blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with H untington's disease Sigurd D. Süßmuth et al. · British Journal of Clinical Pharmacology | 16 Sep 2014 | 170 |
| 8 | Dietary fatty acids influence the growth and fatty acid composition of the yellow mealworm Tenebrio molitor (Coleoptera: Tenebrionidae) Elena Dreassi, Annarita Cito, Assunta Zanfini et al. · Lipids | 12 Jan 2017 | 153 |
| 9 | A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease Marianne R. Smith et al. · Human Molecular Genetics | 16 Jan 2014 | 149 |
| 10 | Signals from the IL-1 Receptor Homolog, Toll, Can Activate an Immune Response in a Drosophila Hemocyte Cell Line Marco Rosetto, Ylva Engström, C. T. Baldari et al. · Biochemical and Biophysical Research Communications | Apr 1995 | 145 |
| 11 | Functional Characterization of WNT7A Signaling in PC12 Cells Andrea Caricasole, Teresa Ferraro, Luisa Iacovelli et al. · Journal of Biological Chemistry | Sep 2003 | 144 |
| 12 | Induction of Dickkopf-1, a Negative Modulator of the Wnt Pathway, Is Required for the Development of Ischemic Neuronal Death Irene Cappuccio, Agata Calderone, Carla Letizia Busceti et al. · Journal of Neuroscience | 9 Mar 2005 | 138 |
| 13 | Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1 Carla Scali, Filippo Caraci, Marco Gianfriddo et al. · Neurobiology of Disease | 18 Aug 2006 | 128 |
| 14 | The Wnt pathway, cell-cycle activation and β-amyloid: novel therapeutic strategies in Alzheimer's disease? Andrea Caricasole, Agata Copani, Alessandra J. Caruso et al. · Trends in Pharmacological Sciences | May 2003 | 126 |
| 15 | A Radial Glia Gene Marker, Fatty Acid Binding Protein 7 (FABP7), Is Involved in Proliferation and Invasion of Glioblastoma Cells Antonella De Rosa, Serena Pellegatta, Marco Rossi et al. · PLoS ONE | 21 Dec 2012 | 124 |
| 16 | Induction of the Wnt Antagonist, Dickkopf-1, Contributes to the Development of Neuronal Death in Models of Brain Focal Ischemia Federica Mastroiacovo, Carla Letizia Busceti, Francesca Biagioni et al. · Journal of Cerebral Blood Flow & Metabolism | Oct 2008 | 119 |
| 17 | Digital Dermoscopy Analysis and Artificial Neural Network for the Differentiation of Clinically Atypical Pigmented Skin Lesions: A Retrospective Study Pietro Rubegni, Marco Burroni, Roberto Perotti et al. · Journal of Investigative Dermatology | Aug 2002 | 118 |
| 18 | Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents Annalaura Brai, Roberta Fazi, Cristina Tintori et al. · Proceedings of the National Academy of Sciences | 26 Apr 2016 | 113 |
| 19 | β-catenin and Gli1 are prognostic markers in glioblastoma Marco Rossi, Letizia Magnoni, Clelia Miracco et al. · Cancer Biology & Therapy | 15 Apr 2011 | 107 |
| 20 | Induction of the Wnt Inhibitor, Dickkopf‐1, Is Associated with Neurodegeneration Related to Temporal Lobe Epilepsy Carla Letizia Busceti, Francesca Biagioni, Eleonora Aronica et al. · Epilepsia | 13 Mar 2007 | 103 |
| 21 | Extracellular Vesicles as Shuttles of Tumor Biomarkers and Anti-Tumor Drugs Davide Zocco, Pietro Ferruzzi, Francesco Cappello et al. · Frontiers in Oncology | 8 Oct 2014 | 103 |
| 22 | Determinants and Biomarkers of Progression Independent of Relapses in Multiple Sclerosis Massimiliano Calabrese et al. · Annals of Neurology | 3 Apr 2024 | 101 |
| 23 | MF59 Adjuvant Enhances the Antibody Response to Recombinant Hepatitis B Surface Antigen Vaccine in Primates Paula Traquina, Maurizio Morandi, Mario Contorni et al. · The Journal of Infectious Diseases | Dec 1996 | 100 |
| 24 | siRNA screen identifies QPCT as a druggable target for Huntington's disease María Jiménez-Sánchez et al. · Nature Chemical Biology | 6 Apr 2015 | 100 |
| 25 | Procognitive and Neuroprotective Activity of a Novel α7 Nicotinic Acetylcholine Receptor Agonist for Treatment of Neurodegenerative and Cognitive Disorders Renza Roncarati, Carla Scali, Thomas A. Comery et al. · Journal of Pharmacology and Experimental Therapeutics | 18 Feb 2009 | 99 |
| 26 | Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells Alessandra J. Caruso, Marta Motolese, Luisa Iacovelli et al. · Journal of Neurochemistry | 30 May 2006 | 99 |
| 27 | Searching for the Perfect Wave: The Effect of Radiofrequency Electromagnetic Fields on Cells Lisa M. Gherardini, Gastone Ciuti, Selene Tognarelli et al. · International Journal of Molecular Sciences | 27 Mar 2014 | 93 |
| 28 | Straightforward Recursive Partitioning Model for Discarding Insoluble Compounds in the Drug Discovery Process Claudia Lamanna, Marta Bellini, Alessandro Padova et al. · Journal of Medicinal Chemistry | 18 Apr 2008 | 84 |
| 29 | Rapid aggregation and assembly in aqueous solution of Aβ (25–35) peptide Lia Millucci, Roberto Raggiaschi, Davide Franceschini et al. · Journal of Biosciences | Jun 2009 | 80 |
| 30 | Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients Stefania Mantovani et al. · Genes and Immunity | 24 Dec 2021 | 79 |
| 31 | Comparison of Cryopreserved HepaRG Cells with Cryopreserved Human Hepatocytes for Prediction of Clearance for 26 Drugs Ugo Zanelli, Nicola Pasquale Caradonna, David Hallifax et al. · Drug Metabolism and Disposition | 14 Oct 2011 | 76 |
| 32 | Pancreatic cancer spheres are more than just aggregates of stem marker-positive cells Margherita Gaviraghi, Patrizia Tunici, Silvia Valensin et al. · Bioscience Reports | 29 Apr 2010 | 76 |
| 33 | Two Sides of the Same Coin: Wnt Signaling in Neurodegeneration and Neuro-Oncology Andrea Caricasole, Annette C. Bakker, Agata Copani et al. · Bioscience Reports | 12 Oct 2005 | 76 |
| 34 | Promising in Vitro anti-Alzheimer Properties for a Ruthenium(III) Complex Luigi Messori, Michela Camarri, Teresa Ferraro et al. · ACS Medicinal Chemistry Letters | 13 Feb 2013 | 75 |
| 35 | Pharmacological inactivation of the prion protein by targeting a folding intermediate Giovanni Spagnolli et al. · Communications Biology | 12 Jan 2021 | 72 |
| 36 | Novel genes and sex differences in COVID-19 severity Raquel Cruz et al. · Human Molecular Genetics | 16 Jun 2022 | 67 |
| 37 | Evaluation of a High-Throughput Fluorescence Assay Method for hERG Potassium Channel Inhibition Arnulf Dorn, Francis Hermann, Andreas Ebneth et al. · SLAS DISCOVERY | Jun 2005 | 67 |
| 38 | Phosphoproteome Analysis Roberto Raggiaschi, Stefano Gotta, Georg C. Terstappen · Bioscience Reports | 4 Feb 2005 | 66 |
| 39 | Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in European males Margherita Baldassarri et al. · EBioMedicine | 26 Feb 2021 | 66 |
| 40 | The adenosine A2A receptor antagonist ZM241385 enhances neuronal survival after oxygen‐glucose deprivation in rat CA1 hippocampal slices Anna Maria Pugliese, Chiara Traini, Sara Cipriani et al. · British Journal of Pharmacology | 5 May 2009 | 63 |
| 41 | Effects of dietary extra-virgin olive oil on behaviour and brain biochemical parameters in ageing rats Vanessa Pitozzi, Michela Jacomelli, Mohamed M. Zaid et al. · British Journal Of Nutrition | 14 Jan 2010 | 63 |
| 42 | A Practical Synthesis of 2,4(5)-Diarylimidazoles from Simple Building Blocks Valentina Zuliani, Giuseppe Cocconcelli, Marco Fantini et al. · The Journal of Organic Chemistry | 9 May 2007 | 62 |
| 43 | The murine interleukin 1β gene: structure and evolution John L. Telford, G Macchia, Annalisa Massone et al. · Nucleic Acids Research | 1986 | 62 |
| 44 | The Wnt Antagonist, Dickkopf-1, as a Target for the Treatment of Neurodegenerative Disorders Filippo Caraci, Carla Letizia Busceti, Francesca Biagioni et al. · Neurochemical Research | 21 Apr 2008 | 61 |
| 45 | Safety, pharmacokinetics, pharmacogenomics and QT concentration−effect modelling of the SirT1 inhibitor selisistat in healthy volunteers Göran Westerberg, Joseph Chiesa, Claus A. F. Andersen et al. · British Journal of Clinical Pharmacology | 16 Sep 2014 | 61 |
| 46 | EV Separation: Release of Intact Extracellular Vesicles Immunocaptured on Magnetic Particles Dario Brambilla, Laura Solá, Anna Maria Ferretti et al. · Analytical Chemistry | 26 Mar 2021 | 59 |
| 47 | DDX3X Helicase Inhibitors as a New Strategy To Fight the West Nile Virus Infection Annalaura Brai, Francesco Martelli, Valentina Riva et al. · Journal of Medicinal Chemistry | 5 Feb 2019 | 58 |
| 48 | Three-dimensional computation of atom depth in complex molecular structures D. Varrazzo, Andrea Bernini, Ottavia Spiga et al. · Computer applications in the biosciences | 12 Apr 2005 | 56 |
| 49 | Screening Technologies for Ion Channel Drug Discovery Georg C. Terstappen, Renza Roncarati, John Dunlop et al. · Future Medicinal Chemistry | May 2010 | 55 |
| 50 | Endogenous activation of group-II metabotropic glutamate receptors inhibits the hypothalamic–pituitary–adrenocortical axis Sergio Scaccianoce, Francesco Matrisciano, Paolo Bianco et al. · Neuropharmacology | Apr 2003 | 55 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.