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Institution · Simcere Pharmaceutical (China)

Most cited papers from Simcere Pharmaceutical (China)

Simcere Pharmaceutical (China)

What are the most cited papers from Simcere Pharmaceutical (China)?

The most cited paper from Simcere Pharmaceutical (China) is "Selenium–GPX4 axis protects follicular helper T cells from ferroptosis" (Yin Yao et al., 2021), with 386 citations. Next come "Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells" (227) and "Efficacy and safety of camrelizumab plus apatinib during the perioperative period in resectable hepatocellular carcinoma: a single-arm, open label, phase II clinical trial" (222).

Showing 50 of 61 papers. Every paper with more than 40 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Selenium–GPX4 axis protects follicular helper T cells from ferroptosis Yin Yao et al. · Nature Immunology 19 Aug 2021 386
2 Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells Tianyu Cao et al. · Cell Open access Apr 2024 227
3 Efficacy and safety of camrelizumab plus apatinib during the perioperative period in resectable hepatocellular carcinoma: a single-arm, open label, phase II clinical trial Yongxiang Xia et al. · Journal for ImmunoTherapy of Cancer Open access Apr 2022 222
4 Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m6A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression Hao Liu et al. · Molecular Cancer Open access 12 Mar 2022 199
5 MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma Yuxiong Lu, Qing Yang, Yubin Su et al. · Cell Death and Disease Open access 19 May 2021 188
6 Optimizing genomic medicine in epilepsy through a gene-customized approach to missense variant interpretation Joshua L. Traynelis, Michael A. Silk, Quanli Wang et al. · Genome Research Open access Sep 2017 188
7 Association of Breast and Ovarian Cancers With Predisposition Genes Identified by Large-Scale Sequencing Hsiao‐Mei Lu, Shuwei Li, Mary Helen Black et al. · JAMA Oncology Open access 21 Aug 2018 184
8 Curcumin inhibits angiogenesis and improves defective hematopoiesis induced by tumor-derived VEGF in tumor model through modulating VEGF-VEGFR2 signaling pathway Zhongping Fu, Xiao Chen, Shengwen Guan et al. · Oncotarget Open access 8 May 2015 124
9 Preparation and characterization of N-succinyl-N′-octyl chitosan micelles as doxorubicin carriers for effective anti-tumor activity XU Xiang-yang, Ling Li, Zhou Jianping et al. · Colloids and Surfaces B Biointerfaces 21 Dec 2006 124
10 NIR-II fluorescence imaging guided tumor-specific NIR-II photothermal therapy enhanced by starvation mediated thermal sensitization strategy Yeneng Dai, Zhiquan Sun, Honghai Zhao et al. · Biomaterials 31 May 2021 118
11 The synergetic effect of edaravone and borneol in the rat model of ischemic stroke Hai‐Yin Wu, Ying Tang, Liyan Gao et al. · European Journal of Pharmacology 27 Jun 2014 118
12 Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir Xiangrui Jiang et al. · Nature Communications Open access 13 Oct 2023 117
13 CAPON-nNOS coupling can serve as a target for developing new anxiolytics Li‐Juan Zhu, Tingyou Li, Chun‐Xia Luo et al. · Nature Medicine 17 Aug 2014 106
14 Sublingual Edaravone Dexborneol for the Treatment of Acute Ischemic Stroke Yu Fu et al. · JAMA Neurology Open access 19 Feb 2024 105
15 Patient-derived xenograft in zebrafish embryos: a new platform for translational research in gastric cancer Jiaqi Wu, Jing Zhai, Chong-Yong Li et al. · Journal of Experimental & Clinical Cancer Research Open access 15 Nov 2017 97
16 nNOS-expressing neurons in the vmPFC transform pPVT-derived chronic pain signals into anxiety behaviors Haiying Liang, Zhijin Chen, Hui Xiao et al. · Nature Communications Open access 19 May 2020 90
17 Multicenter, randomized, double‐blind, controlled trial of treatment of active rheumatoid arthritis with T‐614 compared with methotrexate Liangjing Lu, Chun‐de Bao, Min Dai et al. · Arthritis Care & Research 29 Jun 2009 86
18 Structure-activity relationship of low molecular weight Astragalus membranaceus polysaccharides produced by Bacteroides Yang Cai, Zhenyuan Si, Ying Jiang et al. · Carbohydrate Polymers 19 May 2023 84
19 Optimizing diagnostic strategy for novel coronavirus pneumonia, a multi-center study in Eastern China Jingwen Ai, H. C. Zhang, Teng Xu et al. · medRxiv PreprintOpen access 17 Feb 2020 81
20 Metagenomic next-generation sequencing to identify pathogens and cancer in lung biopsy tissue Yifan Guo, Henan Li, Hongbin Chen et al. · EBioMedicine Open access 25 Oct 2021 78
21 Identification of pathogens in culture-negative infective endocarditis cases by metagenomic analysis Jun Cheng, Huan Hu, Yue Kang et al. · Annals of Clinical Microbiology and Antimicrobials Open access Dec 2018 77
22 Design, Synthesis, Biological Evaluation, and Structure−Activity Relationship (SAR) Discussion of Dipeptidyl Boronate Proteasome Inhibitors, Part I: Comprehensive Understanding of the SAR of α-Amino Acid Boronates Yongqiang Zhu, Xin Zhao, Xinrong Zhu et al. · Journal of Medicinal Chemistry 18 Jun 2009 74
23 Characteristics and clinical trial results of agonistic anti‑CD40 antibodies in the treatment of malignancies (Review) Dake Li, Wen Wang · Oncology Letters Open access 31 Aug 2020 72
24 Engineering cytokines for cancer immunotherapy: a systematic review Yong Fu, Renhong Tang, Xiaofeng Zhao · Frontiers in Immunology ReviewOpen access 6 Jul 2023 71
25 Glutathione S-transferases P1 protects breast cancer cell from adriamycin-induced cell death through promoting autophagy Xiaoliang Dong, Yang Yang, Yi Zhou et al. · Cell Death and Differentiation Open access 25 Jan 2019 70
26 Macrophage‐derived extracellular vesicles regulate follicular activation and improve ovarian function in old mice by modulating local environment Yue Xiao, Xiaoxu Peng, Yue Peng et al. · Clinical and Translational Medicine Open access Oct 2022 69
27 Effect of size on the in vitro / in vivo drug release and degradation of exenatide-loaded PLGA microspheres Xia Lin, Hua Zhe Yang, Lili Su et al. · Journal of Drug Delivery Science and Technology 19 Mar 2018 69
28 Evaluation of characteristics of CD44+CD117+ ovarian cancer stem cells in three dimensional basement membrane extract scaffold versus two dimensional monocultures Junsong Chen, Jing Wang, Dengyu Chen et al. · BMC Cell Biology Open access 31 Jan 2013 69
29 Sensitive determination of 20(S)-protopanaxadiol in rat plasma using HPLC–APCI-MS: Application of pharmacokinetic study in rats Hongcan Ren, Jianguo Sun, Guangji Wang et al. · Journal of Pharmaceutical and Biomedical Analysis 10 Oct 2008 69
30 Variant Interpretation for Cancer (VIC): a computational tool for assessing clinical impacts of somatic variants Max M. He, Quan Li, Muqing Yan et al. · Genome Medicine Open access 23 Aug 2019 66
31 Compound edaravone alleviates lipopolysaccharide (LPS)-induced acute lung injury in mice Zhengping Zhang, Zhaowen Luo, Aijing Bi et al. · European Journal of Pharmacology 25 May 2017 65
32 KRAS Mutation-Responsive miR-139-5p inhibits Colorectal Cancer Progression and is repressed by Wnt Signaling Feng Du, Tianyu Cao, Huahong Xie et al. · Theranostics Open access 2020 63
33 Modulation of age-related insulin sensitivity by VEGF-dependent vascular plasticity in adipose tissues Jennifer Honek, Takahiro Seki, Hideki Iwamoto et al. · Proceedings of the National Academy of Sciences Open access 30 Sep 2014 62
34 Detection of pathogens from resected heart valves of patients with infective endocarditis by next-generation sequencing Jun Cheng, Huan Hu, Fang Wei et al. · International Journal of Infectious Diseases Open access 27 Mar 2019 59
35 Clinical value of metagenomic next-generation sequencing by Illumina and Nanopore for the detection of pathogens in bronchoalveolar lavage fluid in suspected community-acquired pneumonia patients Jing Zhang, Lin Gao, Chi Zhu et al. · Frontiers in Cellular and Infection Microbiology Open access 27 Sep 2022 52
36 Phase II clinical trial of neoadjuvant anti-PD-1 (toripalimab) combined with axitinib in resectable mucosal melanoma Bin Lian, Zhiwang Li, Nan Wu et al. · Annals of Oncology Open access 11 Nov 2023 49
37 Endostar Suppresses Invasion Through Downregulating the Expression of Matrix Metalloproteinase-2/9 in MDA-MB-435 Human Breast Cancer Cells Na Lu, Yun Ling, Ying Gao et al. · Experimental Biology and Medicine 14 May 2008 49
38 Adapt-Kcr: a novel deep learning framework for accurate prediction of lysine crotonylation sites based on learning embedding features and attention architecture Zutan Li, Jingya Fang, Shining Wang et al. · Briefings in Bioinformatics 26 Jan 2022 48
39 NcPath: a novel platform for visualization and enrichment analysis of human non-coding RNA and KEGG signaling pathways Zutan Li, Yuan Zhang, Jingya Fang et al. · Bioinformatics Open access 16 Dec 2022 47
40 Attributable risk and economic cost of hospital admissions for mental disorders due to PM2.5 in Beijing Ziting Wu, Xi Chen, Guoxing Li et al. · The Science of The Total Environment Open access 11 Feb 2020 47
41 Endostar attenuates melanoma tumor growth via its interruption of b-FGF mediated angiogenesis Lijia Xiao, Shucai Yang, Jianhua Hao et al. · Cancer Letters 15 Jan 2015 47
42 Increased Plasma Exposures of Five Protoberberine Alkaloids from Coptidis Rhizoma in Streptozotocin-Induced Diabetic Rats: Is P‐GP Involved? Sen Yu, Yunli Yu, Li Liu et al. · Planta Medica 27 Jan 2010 47
43 Marsdenia tenacissima extract induces G0/G1 cell cycle arrest in human esophageal carcinoma cells by inhibiting mitogen-activated protein kinase (MAPK) signaling pathway Wei Fan, Li Sun, Jing-Qian Zhou et al. · Chinese Journal of Natural Medicines Jun 2015 47
44 Comprehensive identification of FGFR1-4 alterations in 5 557 Chinese patients with solid tumors by next-generation sequencing. Weiquan Gu, Jie Yang, Yong Wang et al. · PubMed Open access 2021 46
45 Molecular targeting of VEGF/VEGFR signaling by the anti-VEGF monoclonal antibody BD0801 inhibits the growth and induces apoptosis of human hepatocellular carcinoma cells in vitro and in vivo Lin Liu, Shukui Qin, Yinghui Zheng et al. · Cancer Biology & Therapy Open access 10 Feb 2017 46
46 IGF-1-induced epithelial–mesenchymal transition in MCF-7 cells is mediated by MUC1 Gaoyong Liao, Mengyu Wang, Yu Ou et al. · Cellular Signalling 24 Jun 2014 46
47 Ultrasensitive detection of multiple Alzheimer's disease biomarkers by SERS-LFA Yuanbao Zhan, Ruihua Fei, Lu Yu et al. · The Analyst 2022 45
48 A CGA/EGFR/GATA2 positive feedback circuit confers chemoresistance in gastric cancer Tianyu Cao et al. · Journal of Clinical Investigation Open access 14 Mar 2022 45
49 A Feedback Circuitry between Polycomb Signaling and Fructose-1, 6-Bisphosphatase Enables Hepatic and Renal Tumorigenesis Kun Lun Liao et al. · Cancer Research 16 Jan 2020 45
50 Five new C21 steroidal glycosides from the stems of Marsdenia tenacissima Hua Zhang, Aimin Tan, Zhang An-yuan et al. · Steroids 18 Nov 2009 45

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.