| 1 |
ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions
Jonathan A C Sterne et al. · BMJ
Open access |
12 Oct 2016 |
20,199 |
| 2 |
The Hallmarks of Aging
Carlos López-Otı́n, Marı́a A. Blasco, Linda Partridge et al. · Cell
Open access |
Jun 2013 |
15,388 |
| 3 |
Planck 2018 results
N. Aghanim et al. · Astronomy and Astrophysics
Open access181 authors |
3 Apr 2020 |
14,737 |
| 4 |
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Clotilde Théry et al. · Journal of Extracellular Vesicles
Open access382 authors |
23 Nov 2018 |
11,535 |
| 5 |
Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide
Tammy Hoffmann, Paul Glasziou, Isabelle Boutron et al. · BMJ
Open access |
7 Mar 2014 |
10,971 |
| 6 |
Planck 2015 results
Peter A. R. Ade et al. · Astronomy and Astrophysics
Open access261 authors |
20 Jun 2016 |
10,771 |
| 7 |
Signatures of mutational processes in human cancer
Australian Pancreatic Cancer Genome Initiative et al. · Nature
Open access |
14 Aug 2013 |
10,284 |
| 8 |
Review of Particle Physics
Masaharu Tanabashi et al. · Physical review. D/Physical review. D.
Open access232 authors |
17 Aug 2018 |
7,268 |
| 9 |
The Gaia mission
T. Prusti et al. · Astronomy and Astrophysics
Open access625 authors |
15 Sep 2016 |
7,118 |
| 10 |
Planck 2013 results. XVI. Cosmological parameters
Peter A. R. Ade et al. · Astronomy and Astrophysics
Open access264 authors |
25 Feb 2014 |
6,598 |
| 11 |
Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries
Giacomo Bellani, John Gerard Laffey, Tài Pham et al. · JAMA
Open access |
22 Feb 2016 |
6,014 |
| 12 |
Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
Bertrand Routy et al. · Science
|
2 Nov 2017 |
5,679 |
| 13 |
Advanced Virgo: a second-generation interferometric gravitational wave detector
F. Acernese et al. · Classical and Quantum Gravity
Open access234 authors |
18 Dec 2014 |
4,224 |
| 14 |
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
Bin Zhou et al. · The Lancet
Open access1,145 authors |
24 Aug 2021 |
3,934 |
| 15 |
GWTC-1: A Gravitational-Wave Transient Catalog of Compact Binary Mergers Observed by LIGO and Virgo during the First and Second Observing Runs
B. P. Abbott et al. · Physical Review X
Open access1,149 authors |
4 Sep 2019 |
3,658 |
| 16 |
Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission
Gill Livingston et al. · The Lancet
Open access |
31 Jul 2024 |
3,635 |
| 17 |
Gravitational Waves and Gamma-Rays from a Binary Neutron Star Merger: GW170817 and GRB 170817A
B. P. Abbott et al. · The Astrophysical Journal Letters
Open access1,154 authors |
16 Oct 2017 |
3,599 |
| 18 |
Comparative Efficacy and Acceptability of 21 Antidepressant Drugs for the Acute Treatment of Adults With Major Depressive Disorder: A Systematic Review and Network Meta-Analysis
Andrea Cipriani, Toshi A. Furukawa, Georgia Salanti et al. · The Lancet
ReviewOpen access |
21 Feb 2018 |
3,587 |
| 19 |
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
Jérôme Galon, Daniela Bruni · Nature Reviews Drug Discovery
Review |
4 Jan 2019 |
3,569 |
| 20 |
LSST: From Science Drivers to Reference Design and Anticipated Data Products
Željko Ivezić et al. · The Astrophysical Journal
Open access327 authors |
10 Mar 2019 |
3,523 |
| 21 |
GW151226: Observation of Gravitational Waves from a 22-Solar-Mass Binary Black Hole Coalescence
B. P. Abbott et al. · Physical Review Letters
Open access977 authors |
15 Jun 2016 |
3,514 |
| 22 |
Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
Marie Vétizou et al. · Science
Open access |
5 Nov 2015 |
3,498 |
| 23 |
Immunogenic Cell Death in Cancer Therapy
Guido Kroemer, Lorenzo Galluzzi, Oliver Kepp et al. · Annual Review of Immunology
Review |
16 Nov 2012 |
3,313 |
| 24 |
Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies
Matthew D. F. McInnes et al. · JAMA
ReviewOpen access |
23 Jan 2018 |
3,242 |
| 25 |
OARSI guidelines for the non-surgical management of knee osteoarthritis
T.E. McAlindon, Raveendhara R. Bannuru, Matthew C. Sullivan et al. · Osteoarthritis and Cartilage
Open access |
24 Jan 2014 |
3,183 |
| 26 |
Immunogenic cell death in cancer and infectious disease
Lorenzo Galluzzi, Aitziber Buqué, Oliver Kepp et al. · Nature reviews. Immunology
Review |
17 Oct 2016 |
3,145 |
| 27 |
Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers
Karoline B. Kuchenbaecker et al. · JAMA
Open access |
20 Jun 2017 |
2,963 |
| 28 |
Biological Functions of Autophagy Genes: A Disease Perspective
Beth Levine, Guido Kroemer · Cell
Open access |
2019 |
2,917 |
| 29 |
Molecular mechanisms of cisplatin resistance
Lorenzo Galluzzi, Laura Senovilla, Ilio Vitale et al. · Oncogene
|
5 Sep 2011 |
2,825 |
| 30 |
Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study
Jerome Rene Lechien et al. · European Archives of Oto-Rhino-Laryngology
Open access |
6 Apr 2020 |
2,771 |
| 31 |
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Daniel J. Klionsky et al. · Autophagy
Open access2,930 authors |
2 Jan 2021 |
2,743 |
| 32 |
Hepatocellular carcinoma
Josep Maria Llovet, Jessica Zucman‐Rossi, Eli Pikarsky et al. · Nature Reviews Disease Primers
Review |
14 Apr 2016 |
2,705 |
| 33 |
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
Mike A. Nalls et al. · The Lancet Neurology
ReviewOpen access270 authors |
6 Nov 2019 |
2,611 |
| 34 |
The molecular machinery of regulated cell death
Daolin Tang, Rui Kang, Tom Vanden Berghe et al. · Cell Research
Open access |
4 Apr 2019 |
2,601 |
| 35 |
GW170817: Measurements of Neutron Star Radii and Equation of State
B. P. Abbott et al. · Physical Review Letters
Open access1,150 authors |
15 Oct 2018 |
2,512 |
| 36 |
Planck 2018 results
Y. Akrami et al. · Astronomy and Astrophysics
Open access175 authors |
9 Oct 2019 |
2,504 |
| 37 |
Genetics of rheumatoid arthritis contributes to biology and drug discovery
Yukinori Okada et al. · Nature
Open access |
24 Dec 2013 |
2,501 |
| 38 |
THE ELEVENTH AND TWELFTH DATA RELEASES OF THE SLOAN DIGITAL SKY SURVEY: FINAL DATA FROM SDSS-III
Shadab Alam et al. · The Astrophysical Journal Supplement Series
Open access304 authors |
27 Jul 2015 |
2,476 |
| 39 |
Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014–2018)
Jean‐Pascal Lefaucheur et al. · Clinical Neurophysiology
Open access |
31 Dec 2019 |
2,413 |
| 40 |
The immune contexture in cancer prognosis and treatment
Wolf H. Fridman, Laurence Zitvogel, Catherine Sautès‐Fridman et al. · Nature Reviews Clinical Oncology
Review |
25 Jul 2017 |
2,367 |
| 41 |
A molecular marker of artemisinin-resistant Plasmodium falciparum malaria
Frédéric Ariey et al. · Nature
Open access |
18 Dec 2013 |
2,218 |
| 42 |
Self-consumption: the interplay of autophagy and apoptosis
Guillermo Mariño, Mireia Niso‐Santano, Eric H. Baehrecke et al. · Nature Reviews Molecular Cell Biology
ReviewOpen access |
8 Jan 2014 |
2,197 |
| 43 |
Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization
Delphine Planas et al. · Nature
Open access |
8 Jul 2021 |
2,187 |
| 44 |
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
Franck Pagès et al. · The Lancet
|
May 2018 |
2,133 |
| 45 |
Gaia Data Release 1
A. G. A. Brown et al. · Astronomy and Astrophysics
Open access591 authors |
15 Sep 2016 |
2,113 |
| 46 |
Autophagy and Aging
David Chaim Rubinsztein, Guillermo Mariño, Guido Kroemer · Cell
Open access |
Sep 2011 |
2,112 |
| 47 |
European guideline for the diagnosis and treatment of insomnia
Dieter Wilhelm Riemann et al. · Journal of Sleep Research
|
5 Sep 2017 |
2,100 |
| 48 |
70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer
Fátima Cardoso et al. · New England Journal of Medicine
Open access |
24 Aug 2016 |
2,097 |
| 49 |
THE BARYON OSCILLATION SPECTROSCOPIC SURVEY OF SDSS-III
Kyle S. Dawson et al. · The Astronomical Journal
Open access165 authors |
6 Dec 2012 |
2,091 |
| 50 |
Gut microbiota-derived metabolites as key actors in inflammatory bowel disease
Aonghus Lavelle, Harry Sokol · Nature Reviews Gastroenterology & Hepatology
Review |
19 Feb 2020 |
2,062 |