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Most cited papers from South College

What are the most cited papers from South College?

The most cited paper from South College is "Drugs for bad bugs: confronting the challenges of antibacterial discovery" (David J Payne, Michael N. Gwynn, David J. Holmes et al., 2006), with 2,527 citations. Next come "Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia" (1,541) and "Drug–target residence time and its implications for lead optimization" (1,476).

Showing 50 of 61 papers. Every paper with more than 233 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Drugs for bad bugs: confronting the challenges of antibacterial discovery David J Payne, Michael N. Gwynn, David J. Holmes et al. · Nature Reviews Drug Discovery Review 8 Dec 2006 2,527
2 Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia Mark A. Dawson et al. · Nature Open access Oct 2011 1,541
3 Drug–target residence time and its implications for lead optimization Robert A. Copeland, David L. Pompliano, Thomas D. Meek · Nature Reviews Drug Discovery Review 4 Aug 2006 1,476
4 The complete genome of the hyperthermophilic bacterium Aquifex aeolicus Gerard Deckert, Patrick V. Warren, Terry Gaasterland et al. · Nature Open access Mar 1998 1,112
5 Updating and further expanding GSK's solvent sustainability guide Catherine M. Alder, John D. Hayler, Richard K. Henderson et al. · Green Chemistry 2016 1,045
6 Thousands of chemical starting points for antimalarial lead identification Francisco‐Javier Gamo, Laura María Sanz, Jaume Vidal et al. · Nature May 2010 1,023
7 Deep Eutectic Solvents: Sustainable Media for Nanoscale and Functional Materials Durgesh V. Wagle, Hua Zhao, Gary A. Baker · Accounts of Chemical Research 3 Jun 2014 892
8 A unified analysis of the English bare plural Greg N. Carlson · Linguistics and Philosophy 1977 755
9 Vaccination against Lyme Disease with Recombinant Borrelia burgdorferi Outer-Surface Lipoprotein A with Adjuvant Allen C. Steere, Vijay K. Sikand, François Meurice et al. · New England Journal of Medicine Open access 23 Jul 1998 752
10 Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs Gary G. Liversidge, Kenneth C. Cundy · International Journal of Pharmaceutics Oct 1995 739
11 Approaches for enhancing oral bioavailability of peptides and proteins Jwala Renukuntla, Aswani Dutt Vadlapudi, Ashaben Patel et al. · International Journal of Pharmaceutics Open access 18 Feb 2013 676
12 Parallel adaptive radiations in two major clades of placental mammals Ole Madsen, Mark Scally, Christophe J. Douady et al. · Nature Feb 2001 657
13 Prediction of Protein−Ligand Interactions. Docking and Scoring: Successes and Gaps Andrew R. Leach, Brian K. Shoichet, Catherine E. Peishoff · Journal of Medicinal Chemistry 28 Sep 2006 650
14 Development of immuno-oncology drugs — from CTLA4 to PD1 to the next generations Axel Hoos · Nature Reviews Drug Discovery Review 11 Mar 2016 616
15 Reductive carboxylation supports redox homeostasis during anchorage-independent growth Lei Jiang, Alexander A. Shestov, Pamela M. Swain et al. · Nature Open access Apr 2016 609
16 Mechanisms, Capabilities, and Applications of High‐Resolution Electrohydrodynamic Jet Printing M. Serdar Önses, Erick Sutanto, Placid Mathew Ferreira et al. · Small 29 Jun 2015 602
17 The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future Steven M. Mennen et al. · Organic Process Research & Development Open access 7 May 2019 589
18 Residence Time of Receptor−Ligand Complexes and Its Effect on Biological Function Peter J. Tummino, Robert A. Copeland · Biochemistry 16 Apr 2008 555
19 BET inhibitor resistance emerges from leukaemia stem cells Chun Yew Fong et al. · Nature Open access Sep 2015 553
20 GPU-Accelerated Molecular Dynamics and Free Energy Methods in Amber18: Performance Enhancements and New Features Tai‐Sung Lee, David S. Cerutti, Dan Mermelstein et al. · Journal of Chemical Information and Modeling Open access 10 Sep 2018 516
21 Big opportunities for small molecules in immuno-oncology Jerry L. Adams, James F . Smothers, Roopa Srinivasan et al. · Nature Reviews Drug Discovery Review 31 Jul 2015 473
22 Activity Demands During Multi-Directional Team Sports: A Systematic Review Jeffrey B. Taylor, Alexis A. Wright, Steven L. Dischiavi et al. · Sports Medicine Review 11 Aug 2017 440
23 Long Distance Agreement in Hindi-Urdu Rajesh Bhatt · Natural Language & Linguistic Theory Nov 2005 438
24 Comparison of RNA-seq and microarray-based models for clinical endpoint prediction Wenqian Zhang et al. · Genome biology Open access 24 Jun 2015 432
25 Probabilistic Relationships between Ground-Motion Parameters and Modified Mercalli Intensity in California C. Bruce Worden, Matt Gerstenberger, David A. Rhoades et al. · Bulletin of the Seismological Society of America Feb 2012 418
26 Validation Studies of the Site-Directed Docking Program LibDock Shashidhar N. Rao, Martha S. Head, Amit Kulkarni et al. · Journal of Chemical Information and Modeling Open access Nov 2007 413
27 Cycloaddition Chemistry of Organic Molecules with Semiconductor Surfaces Robert J. Hamers, Sarah K. Coulter, Mark D. Ellison et al. · Accounts of Chemical Research 2 Jun 2000 408
28 The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum Andreas Ruepp, Werner Graml, Leticia Santos et al. · Nature Open access Sep 2000 402
29 Differential cytokine expression in avian cells in response to invasion by Salmonella typhimurium, Salmonella enteritidis and Salmonella gallinarum The GenBank accession numbers for the sequences reported in this paper are AI982185 for chicken IL-6 cDNA and AJ250838 for the partial chicken IL-6 genomic sequence, respectively. Pete Kaiser, Lisa M. Rothwell, Edouard E. Galyov et al. · Microbiology Dec 2000 399
30 Universal trees based on large combined protein sequence data sets James R. Brown, Christophe J. Douady, Michael J. Italia et al. · Nature Genetics Jul 2001 391
31 Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin Steven D. Knight et al. · ACS Medicinal Chemistry Letters Open access 19 Jan 2010 375
32 Structure and sequence analysis of Yersinia YadA and Moraxella UspAs reveal a novel class of adhesins Egbert Hoiczyk, Andreas Roggenkamp, Marisa Reichenbecher et al. · The EMBO Journal Open access 15 Nov 2000 363
33 An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure Kevin S. Thorneloe et al. · Science Translational Medicine 7 Nov 2012 347
34 The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors Daniel Zingg, Julien Debbache, Simon M. Schaefer et al. · Nature Communications Open access 22 Jan 2015 340
35 Effects of amendment of biochar-manure compost in conjunction with pyroligneous solution on soil quality and wheat yield of a salt-stressed cropland from Central China Great Plain Muhammad Siddique Lashari, Yuming Liu, Lianqing Li et al. · Field Crops Research 28 Feb 2013 329
36 A genomic analysis of two‐component signal transduction in Streptococcus pneumoniae John P. Throup, Kristin K. Koretke, Alexander P. Bryant et al. · Molecular Microbiology Open access Feb 2000 320
37 Evidentiality, logophoricity and the syntactic representation of pragmatic features Margaret Speas · Lingua 19 May 2003 320
38 Open-Air Alkylation Reactions in Photoredox-Catalyzed DNA-Encoded Library Synthesis James P. Phelan, Simon B. Lang, Jaehoon Sim et al. · Journal of the American Chemical Society Open access 12 Feb 2019 318
39 Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery Thomas G. Davies et al. · Journal of Medicinal Chemistry Open access 31 Mar 2016 315
40 Iron acquisition and virulence in Helicobacter pylori: a major role for FeoB, a high‐affinity ferrous iron transporter Jyoti Velayudhan, Nicky J. Hughes, Andrew A. McColm et al. · Molecular Microbiology Open access Jul 2000 315
41 Identification of Novel Inhibitors of the Transforming Growth Factor β1 (TGF-β1) Type 1 Receptor (ALK5) James F. Callahan, Joelle L. Burgess, James A. Fornwald et al. · Journal of Medicinal Chemistry Open access 30 Jan 2002 311
42 Modeling Individual Preferences for Ownership and Sharing of Autonomous Vehicle Technologies Patrícia Sauri Lavieri, Venu M. Garikapati, Chandra R. Bhat et al. · Transportation Research Record Journal of the Transportation Research Board 2017 310
43 On the Evolution of Protein Folds: Are Similar Motifs in Different Protein Folds the Result of Convergence, Insertion, or Relics of an Ancient Peptide World? Andrei N. Lupas, Chris Paul Ponting, Robert B. Russell · Journal of Structural Biology May 2001 308
44 Implications of early and guideline adherent physical therapy for low back pain on utilization and costs John D. Childs, Julie M. Fritz, Samuel Shangwu Wu et al. · BMC Health Services Research Open access 8 Apr 2015 306
45 Verb movement and the subject position in Yiddish Molly Diesing · Natural Language & Linguistic Theory Feb 1990 301
46 Is Motor Impairment in Autism Spectrum Disorder Distinct From Developmental Coordination Disorder? A Report From the SPARK Study Anjana Narayan Bhat · Physical Therapy Open access 19 Dec 2019 298
47 Drug particle size reduction for decreasing gastric irritancy and enhancing absorption of naproxen in rats Gary G. Liversidge, Phil Conzentino · International Journal of Pharmaceutics Oct 1995 296
48 Characterization of a novel chicken muscle disorder through differential gene expression and pathway analysis using RNA-sequencing Marie F Mutryn, Erin M. Brannick, Weixuan Fu et al. · BMC Genomics Open access 20 May 2015 287
49 A functional genomic analysis of type 3 Streptococcus pneumoniae virulence Gee W. Lau, Sauli Haataja, Michael A. Lonetto et al. · Molecular Microbiology May 2001 286
50 The structure of coxsackievirus B3 at 3.5 å resolution J.K. Muckelbauer, Marcia J. Kremer, Iwona Minor et al. · Structure Open access Jul 1995 281

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.