| 1 |
Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women
Jorma A. Paavonen et al. · The Lancet
|
Jul 2009 |
1,663 |
| 2 |
Overall efficacy of HPV-16/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasia: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial
Matti Lehtinen et al. · The Lancet Oncology
|
9 Nov 2011 |
708 |
| 3 |
Light-induced cell damage in live-cell super-resolution microscopy
Sina Wäldchen, Julian Lehmann, Teresa Klein et al. · Scientific Reports
Open access |
20 Oct 2015 |
573 |
| 4 |
Cross-protective efficacy of HPV-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by non-vaccine oncogenic HPV types: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial
Cosette Marie Wheeler et al. · The Lancet Oncology
|
9 Nov 2011 |
515 |
| 5 |
A role for nitrilase 3 in the regulation of root morphology in sulphur‐starving Arabidopsis thaliana
Alexandra Kutz, Axel Müller, Peter Hennig et al. · The Plant Journal
Open access |
Apr 2002 |
243 |
| 6 |
Natural History of Progression of HPV Infection to Cervical Lesion or Clearance: Analysis of the Control Arm of the Large, Randomised PATRICIA Study
Unnop Jaisamrarn et al. · PLoS ONE
Open access |
19 Nov 2013 |
218 |
| 7 |
Intracellular metabolism of 4-hydroxynonenal
Werner Siems, Tilman Grune · Molecular Aspects of Medicine
|
21 Jun 2003 |
211 |
| 8 |
Immunogenicity and safety of the HPV-16/18 AS04-adjuvanted vaccine administered as a 2-dose schedule compared to the licensed 3-dose schedule
Barbara Romanowski, Tino F. Schwarz, Linda M. Ferguson et al. · Human Vaccines
Open access |
Dec 2011 |
194 |
| 9 |
A role for β‐sitosterol to stigmasterol conversion in plant–pathogen interactions
Thomas Griebel, Jürgen Zeier · The Plant Journal
|
26 Apr 2010 |
193 |
| 10 |
S3-Leitlinie Kolorektales Karzinom Version 1.0 - Juni 2013 AWMF-Registernummer: 021/007OL
Christian Peter Pox et al. · Zeitschrift für Gastroenterologie
Open access |
16 Aug 2013 |
183 |
| 11 |
The Arabidopsis transcription factor bZIP11 activates auxin-mediated transcription by recruiting the histone acetylation machinery
Christoph Weiste, Wolfgang Dröge‐Laser · Nature Communications
Open access |
27 May 2014 |
180 |
| 12 |
Significance of psychosocial factors in cardiology: update 2018
Christian Albus, Christiane Waller, Kurt Fritzsche et al. · Clinical Research in Cardiology
Open access |
10 May 2019 |
176 |
| 13 |
Randomized clinical trial comparing lightweight composite mesh with polyester or polypropylene mesh for incisional hernia repair
J. Conze, Andrew N. Kingsnorth, Jean Bernard Flament et al. · British journal of surgery
Open access |
24 Nov 2005 |
169 |
| 14 |
Identification of Arabidopsis thaliana phloem RNAs provides a search criterion for phloem‐based transcripts hidden in complex datasets of microarray experiments
Rosalia Deeken, Peter Ache, Inga Kajahn et al. · The Plant Journal
|
14 May 2008 |
160 |
| 15 |
Immunogenicity and tolerability of an HPV-16/18 AS04-adjuvanted prophylactic cervical cancer vaccine in women aged 15–55 years
Tino F. Schwarz, Marek Spaczyński, Achim Schneider et al. · Vaccine
|
26 Nov 2008 |
152 |
| 16 |
Efficacy of the human papillomavirus (HPV)‐16/18 AS04‐adjuvanted vaccine in women aged 15–25 years with and without serological evidence of previous exposure to HPV‐16/18
Anne Szarewski et al. · International Journal of Cancer
Open access |
19 Aug 2011 |
143 |
| 17 |
Safety and immunogenicity of three different formulations of an adjuvanted varicella-zoster virus subunit candidate vaccine in older adults: A phase II, randomized, controlled study
Roman Chlíbek, Jan Smetana, Karlis Pauksens et al. · Vaccine
|
6 Feb 2014 |
137 |
| 18 |
Biodiversity of arbuscular mycorrhizal fungi in roots and soils of two salt marshes
Petra Wilde, A. H. E. Manal, Marc Stodden et al. · Environmental Microbiology
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10 Feb 2009 |
131 |
| 19 |
Intestinal transit and systemic metabolism of apple polyphenols
Kathrin Kahle, Michael Andreas Kempf, Peter H. Schreier et al. · European Journal of Nutrition
|
23 Dec 2010 |
129 |
| 20 |
Metabolic fate of 4-hydroxynonenal in hepatocytes: 1,4-dihydroxynonene is not the main product
Werner G. Siems, Helmward Zöllner, Tilman Grune et al. · Journal of Lipid Research
Open access |
Mar 1997 |
125 |
| 21 |
Novel findings on the metabolic effects of the low glycaemic carbohydrate isomaltulose (Palatinose™)
Ines Holub, Andrea Gostner, Stephan Theis et al. · British Journal Of Nutrition
Open access |
9 Mar 2010 |
125 |
| 22 |
Erythrocyte free radical and energy metabolism.
Siems Wg, Olaf Sommerburg, Tilman Grune · PubMed
|
Feb 2000 |
124 |
| 23 |
Long-term immunogenicity and safety of an investigational herpes zoster subunit vaccine in older adults
Roman Chlíbek, Karlis Pauksens, Lars Rombo et al. · Vaccine
Open access |
2 Oct 2015 |
123 |
| 24 |
Efficacy of Human Papillomavirus 16 and 18 (HPV-16/18) AS04-Adjuvanted Vaccine against Cervical Infection and Precancer in Young Women: Final Event-Driven Analysis of the Randomized, Double-Blind PATRICIA Trial
Dan Apter et al. · Clinical and Vaccine Immunology
Open access |
5 Feb 2015 |
122 |
| 25 |
β‐Carotene cleavage products induce oxidative stress in vitro by impairing mitochondrial respiration
Werner Siems, Olaf Sommerburg, Lorenz Schild et al. · The FASEB Journal
|
21 Jun 2002 |
119 |
| 26 |
Single dose vaccination with AS03-adjuvanted H5N1 vaccines in a randomized trial induces strong and broad immune responsiveness to booster vaccination in adults
Tino F. Schwarz, Thomas Horacek, Markus Knuf et al. · Vaccine
|
16 Jul 2009 |
119 |
| 27 |
Surgery of the lateral skull base: a 50-year endeavour
E. Zanoletti et al. · Acta Otorhinolaryngologica Italica
Open access |
24 May 2019 |
118 |
| 28 |
4-Hydroxynonenal formation during ischemia and reperfusion of rat small intestine
Werner G. Siems, Tilman Grune, H. Esterbauer · Life Sciences
|
Jul 1995 |
118 |
| 29 |
Immune response to human papillomavirus after prophylactic vaccination with AS04-adjuvanted HPV-16/18 vaccine: Improving upon nature
Tino F. Schwarz, Oberdan Léo · Gynecologic Oncology
|
25 Jul 2008 |
118 |
| 30 |
Impact of adjuvants on CD4+ T cell and B cell responses to a protein antigen vaccine: Results from a phase II, randomized, multicenter trial
Geert G Leroux-Roels et al. · Clinical Immunology
Open access |
26 May 2016 |
116 |
| 31 |
Clinical features of crimean-congo haemorrhagic fever in the united arab emirates
Tino F. Schwarz, H Nsanze, A. Mahmood Ameen · Infection
|
Nov 1997 |
109 |
| 32 |
Plant roots employ cell-layer-specific programs to respond to pathogenic and beneficial microbes
Christian Fröschel, Jaqueline Komorek, Agnès Attard et al. · Cell Host & Microbe
Open access |
29 Dec 2020 |
107 |
| 33 |
Prior human papillomavirus‐16/18 AS04‐adjuvanted vaccination prevents recurrent high grade cervical intraepithelial neoplasia after definitive surgical therapy: Post‐hoc analysis from a randomized controlled trial
Suzanne Marie Garland et al. · International Journal of Cancer
Open access |
19 Aug 2016 |
105 |
| 34 |
Immune response to the HPV-16/18 AS04-adjuvanted vaccine administered as a 2-dose or 3-dose schedule up to 4 years after vaccination
Barbara Romanowski, Tino F. Schwarz, Linda M. Ferguson et al. · Human Vaccines & Immunotherapeutics
Open access |
27 Feb 2014 |
99 |
| 35 |
The low energy signaling network
Filipa Tomé, Thomas Nägele, Mattia Adamo et al. · Frontiers in Plant Science
Open access |
17 Jul 2014 |
97 |
| 36 |
Improved antioxidative protection in winter swimmers
Werner G. Siems · QJM
|
Apr 1999 |
97 |
| 37 |
Sustained immunogenicity of the HPV-16/18 AS04-adjuvanted vaccine administered as a two-dose schedule in adolescent girls: Five-year clinical data and modeling predictions from a randomized study
Barbara Romanowski, Tino F. Schwarz, Linda Ferguson et al. · Human Vaccines & Immunotherapeutics
Open access |
15 Jul 2015 |
96 |
| 38 |
Functional abnormalities in P0-deficient mice resemble human hereditary neuropathies linked to P0 gene mutations
Jürgen Zielasek, Rudolf Martini, Klaus V. Toyka · Muscle & Nerve
|
Aug 1996 |
95 |
| 39 |
A randomized, double-blind trial to evaluate immunogenicity and safety of 13-valent pneumococcal conjugate vaccine given concomitantly with trivalent influenza vaccine in adults aged ≥65 years
Tino F. Schwarz, Johan Flamaing, Hans C Rümke et al. · Vaccine
Open access |
19 Jun 2011 |
94 |
| 40 |
β-Carotene cleavage products after oxidation mediated by hypochlorous acid—a model for neutrophil-derived degradation
Olaf Sommerburg, Claus‐Dieter Langhans, Jürgen Arnhold et al. · Free Radical Biology and Medicine
|
21 Nov 2003 |
94 |
| 41 |
Safety and reactogenicity profile of an adjuvanted H5N1 pandemic candidate vaccine in adults within a phase III safety trial
Hans C Rümke, José-María Bayas, José-Ramón de Juanes et al. · Vaccine
|
2 Apr 2008 |
94 |
| 42 |
Increased Levels of 4-Hydroxynonenal Modified Proteins in Plasma of Children with Autoimmune Diseases
Tilman Grune, Philip Michel, Nicolle Sitte et al. · Free Radical Biology and Medicine
|
1997 |
93 |
| 43 |
More than a marine propeller – the flagellum of the probiotic Escherichia coli strain Nissle 1917 is the major adhesin mediating binding to human mucus
Anja Troge, Wolfgang M. Scheppach, Bjoern O. Schroeder et al. · International Journal of Medical Microbiology
|
4 Nov 2012 |
85 |
| 44 |
Efficacy of the HPV-16/18 AS04-Adjuvanted Vaccine Against Low-Risk HPV Types (PATRICIA Randomized Trial): An Unexpected Observation
Anne Szarewski et al. · The Journal of Infectious Diseases
Open access |
3 Oct 2013 |
84 |
| 45 |
Prevalence and risk factors for cervical HPV infection and abnormalities in young adult women at enrolment in the multinational PATRICIA trial
Édith Roset Bahmanyar et al. · Gynecologic Oncology
Open access |
29 Aug 2012 |
83 |
| 46 |
Clinical update of the AS04-Adjuvanted human Papillomavirus-16/18 cervical cancer vaccine, cervarix®
Tino F. Schwarz · Advances in Therapy
|
Nov 2009 |
81 |
| 47 |
High‐throughput protoplast transactivation (PTA) system for the analysis of Arabidopsis transcription factor function
Nora Wehner, Laura Helena Hartmann, Andrea Ehlert et al. · The Plant Journal
Open access |
12 Jul 2011 |
79 |
| 48 |
Lycopene and β‐carotene decompose more rapidly than lutein and zeaxanthin upon exposure to various pro‐oxidants in vitro
Werner G. Siems, Olaf Sommerburg, Frederik J.G.M. van Kuijk · BioFactors
|
1999 |
78 |
| 49 |
Increased levels of 4‐hydroxynonenal in human monocytes fed with malarial pigment hemozoin A possible clue for hemozoin toxicity
Evelin Schwarzer, Oliver Müller, Paolo Arese et al. · FEBS Letters
Open access |
17 Jun 1996 |
75 |
| 50 |
Pseudomonas syringae infection triggers de novo synthesis of phytosphingosine from sphinganine in Arabidopsis thaliana
Markus Peer, Martin Stegmann, Martin Johannes Mueller et al. · FEBS Letters
Open access |
21 Aug 2010 |
73 |