| 1 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Richard Karlsson Linnér et al. · Nature Genetics
Open access |
9 Jan 2019 |
857 |
| 2 |
Whole-genome sequence variation, population structure and demographic history of the Dutch population
Laurent C. Francioli et al. · Nature Genetics
Open access |
29 Jun 2014 |
732 |
| 3 |
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene
Aude Nicolas et al. · Neuron
Open access540 authors |
Mar 2018 |
728 |
| 4 |
The LOFAR Two-metre Sky Survey
T. W. Shimwell et al. · Astronomy and Astrophysics
Open access107 authors |
27 Sep 2018 |
596 |
| 5 |
Time-Resolved Holography with Photoelectrons
Ymkje Huismans et al. · Science
Open access |
17 Dec 2010 |
581 |
| 6 |
Disease variants alter transcription factor levels and methylation of their binding sites
Marc Jan Bonder et al. · Nature Genetics
Open access |
5 Dec 2016 |
567 |
| 7 |
Identification of context-dependent expression quantitative trait loci in whole blood
Daria V. Zhernakova et al. · Nature Genetics
Open access |
5 Dec 2016 |
519 |
| 8 |
Detection of long repeat expansions from PCR-free whole-genome sequence data
Egor Dolzhenko et al. · Genome Research
Open access |
8 Sep 2017 |
445 |
| 9 |
Genetic and environmental influences interact with age and sex in shaping the human methylome
Jenny van Dongen et al. · Nature Communications
Open access |
7 Apr 2016 |
439 |
| 10 |
The pharmacokinetic-pharmacodynamic relationship for mycophenolate mofetil in renal transplantation*
Michael Hale, Andrew J. Nicholls, Roy E S Bullingham et al. · Clinical Pharmacology & Therapeutics
|
Dec 1998 |
400 |
| 11 |
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits
Eleonora Porcu et al. · Nature Communications
Open access135 authors |
24 Jul 2019 |
360 |
| 12 |
Randomised phase II study of cisplatin and 5-fluorouracil (5-FU) versus cisplatin alone in advanced squamous cell oesophageal cancer
Harry Bleiberg, Thierry Conroy, Bernard Paillot et al. · European Journal of Cancer
|
Jul 1997 |
353 |
| 13 |
Systematic effects in LOFAR data: A unified calibration strategy
F. de Gasperin, Tammo Jan Dijkema, A. Drabent et al. · Astronomy and Astrophysics
Open access |
4 Oct 2018 |
213 |
| 14 |
Physical Activity as a Critical Component of First-Line Treatment for Elevated Blood Pressure or Cholesterol: Who, What, and How?: A Scientific Statement From the American Heart Association
Bethany Barone Gibbs, Marie‐France Hivert, Gerald J. Jerome et al. · Hypertension
|
2 Jun 2021 |
201 |
| 15 |
Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis
W Van Rheenen et al. · European Journal of Human Genetics
Open access |
28 Jun 2018 |
200 |
| 16 |
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
Melinda C Mills et al. · Nature Human Behaviour
Open access252 authors |
Jul 2021 |
166 |
| 17 |
Underpinning tectonic reconstructions of the western Mediterranean region with dynamic slab evolution from 3‐D numerical modeling
Maria V. Chertova, Wim Spakman, T. Geenen et al. · Journal of Geophysical Research Solid Earth
|
18 Jun 2014 |
134 |
| 18 |
AFiD-GPU: A versatile Navier–Stokes solver for wall-bounded turbulent flows on GPU clusters
Xiaojue Zhu, Everett H. Phillips, Vamsi Spandan et al. · Computer Physics Communications
Open access |
5 Apr 2018 |
127 |
| 19 |
Studies on acrylamide levels in roasting, storage and brewing of coffee
Ingo Lantz, Ruediger Ternité, J. Wilkens et al. · Molecular Nutrition & Food Research
|
19 Oct 2006 |
124 |
| 20 |
Structure and evolution of high-mass stellar mergers
E. Glebbeek, Evghenii Gaburov, Simon Portegies Zwart et al. · Monthly Notices of the Royal Astronomical Society
Open access |
6 Aug 2013 |
122 |
| 21 |
A data infrastructure reference model with applications: towards realization of a ScienceTube vision with a data replication service
Morris Riedel et al. · Journal of Internet Services and Applications
Open access |
2013 |
111 |
| 22 |
Event generation and statistical sampling for physics with deep generative models and a density information buffer
Sydney Otten, S. Caron, Wieske de Swart et al. · Radboud Repository (Radboud University)
|
2021 |
104 |
| 23 |
The LOFAR pilot surveys for pulsars and fast radio transients
Thijs Coenen et al. · Astronomy and Astrophysics
Open access |
2 Aug 2014 |
104 |
| 24 |
Modeling of PMS Ae/Fe stars using UV spectra
P. F. C. Blondel, H. R. E. Tjin A Djie · Astronomy and Astrophysics
Open access |
Sep 2006 |
101 |
| 25 |
Furan in coffee: pilot studies on formation during roasting and losses during production steps and consumer handling
Helmut Guenther, Katrin Hoenicke, Steven Biesterveld et al. · Food Additives & Contaminants Part A
Open access |
9 Jan 2010 |
92 |
| 26 |
CLTune: A Generic Auto-Tuner for OpenCL Kernels
Cedric Nugteren, Valeriu Codreanu
Conference paperOpen access |
Sep 2015 |
89 |
| 27 |
Sub-arcsecond imaging with the International LOFAR Telescope
Leah K. Morabito et al. · Astronomy and Astrophysics
Open access |
9 Apr 2021 |
88 |
| 28 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences 1
Richard Karlsson Linnér et al. · bioRxiv (Cold Spring Harbor Laboratory)
PreprintOpen access |
8 Feb 2018 |
87 |
| 29 |
National records of 3000 European bee and hoverfly species: A contribution to pollinator conservation
Sara Reverté et al. · Insect Conservation and Diversity
Open access107 authors |
12 Sep 2023 |
86 |
| 30 |
24.77 Pflops on a Gravitational Tree-Code to Simulate the Milky Way Galaxy with 18600 GPUs
Jeroen Bédorf, Evghenii Gaburov, Michiko S. Fujii et al.
Conference paperOpen access |
Nov 2014 |
81 |
| 31 |
Effect of Roasting Conditions on Reduction of Ochratoxin A in Coffee
Gerrit H. D. van der Stegen, Paulus J. M. Essens, Joost van der Lijn · Journal of Agricultural and Food Chemistry
|
28 Sep 2001 |
80 |
| 32 |
Tamsulosin: 3-Year Long-Term Efficacy and Safety in Patients with Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Obstruction: Analysis of a European, Multinational, Multicenter, Open-Label Study
Claude C. Schulman, J. Cortvriend, Ulrich Jonas et al. · European Urology
|
1999 |
79 |
| 33 |
Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels
Elisabeth M. van Leeuwen et al. · Nature Communications
Open access125 authors |
9 Mar 2015 |
75 |
| 34 |
DNA methylation signatures of educational attainment
Jenny van Dongen et al. · npj Science of Learning
Open access |
23 Mar 2018 |
70 |
| 35 |
Constraining cold accretion on to supermassive black holes: molecular gas in the cores of eight brightest cluster galaxies revealed by joint CO and CN absorption
Tom Rose et al. · Monthly Notices of the Royal Astronomical Society
Open access |
Aug 2019 |
66 |
| 36 |
Unleashing the potential of digital pathology data by training computer-aided diagnosis models without human annotations
Niccolò Marini, Stefano Marchesin, Sebastian Otálora et al. · npj Digital Medicine
Open access |
22 Jul 2022 |
65 |
| 37 |
CUBu: Universal Real-Time Bundling for Large Graphs
Matthew van der Zwan, Valeriu Codreanu, Alexandru Cristian Telea · IEEE Transactions on Visualization and Computer Graphics
Open access |
7 Jan 2016 |
64 |
| 38 |
Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults
Jenny van Dongen et al. · Biological Psychiatry
Open access |
Mar 2019 |
62 |
| 39 |
Photic stimulation — standardization of screening methods
Dorothée Kasteleijn‐Nolst Trenité, Colin D. Binnie, Graham F. A. Harding et al. · Neurophysiologie Clinique
|
Sep 1999 |
60 |
| 40 |
Using the Network Description Language in Optical Networks
Jeroen van der Ham, Paola Grosso, Ronald van der Pol et al.
Conference paperOpen access |
May 2007 |
59 |
| 41 |
A distributed topology information system for optical networks based on the semantic web
Jeroen van der Ham, Freek Dijkstra, Paola Grosso et al. · Optical Switching and Networking
Open access |
20 Feb 2008 |
54 |
| 42 |
Intratumoral low-dose interleukin-2 induces rejection of distant solid tumour
Riks A. Maas, D. Henk, Jan R.T. van Weering et al. · Cancer Immunology Immunotherapy
Open access |
Nov 1991 |
54 |
| 43 |
Predicting atmospheric optical properties for radiative transfer computations using neural networks
Menno Veerman, Robert L. Pincus, Robin Stoffer et al. · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
Open access |
15 Feb 2021 |
53 |
| 44 |
Template matching as a tool for annotation of tomograms of stained biological structures
Misjaël N. Lebbink, Willie J. C. Geerts, Theo P. van der Krift et al. · Journal of Structural Biology
Open access |
23 Dec 2006 |
53 |
| 45 |
Recommendations for Services in a FAIR Data Ecosystem
Hylke Koers, Daniel Bangert, Emilie Hermans et al. · Patterns
Open access |
7 Jul 2020 |
52 |
| 46 |
Flexible transgastric peritoneoscopy: A novel approach to diagnostic and therapeutic interventions in the peritoneal cavity
Anthony Nicholas Kalloo, Sergey V. Kantsevoy, Vikesh K. Singh et al. · Gastroenterology
|
Apr 2000 |
51 |
| 47 |
Multipathing with MPTCP and OpenFlow
Ronald van der Pol, Sander Boele, Freek Dijkstra et al.
Conference paper |
Nov 2012 |
51 |
| 48 |
The functional adaptation of the diseased kidney. 3. Ammonium excretion.
Evert J. Dorhout-Mees, Marcel Cerqueira César Machado, Eduardo Slatopolsky et al. · Journal of Clinical Investigation
Open access |
Mar 1966 |
51 |
| 49 |
Contact sensitization by alternative topical medicaments containing plant extracts
D. P. Bruynzeel, Willem G. van Ketel, E. GORDON YOUNG et al. · Contact Dermatitis
|
Apr 1992 |
51 |
| 50 |
Deep sub-arcsecond wide-field imaging of the Lockman Hole field at 144 MHz
Frits Sweijen, Reinout J. van Weeren, Huub J. A. Röttgering et al. · Nature Astronomy
Open access |
27 Jan 2022 |
46 |