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Most cited papers from Swim Across America

What are the most cited papers from Swim Across America?

The most cited paper from Swim Across America is "PD-1 Blockade in Tumors with Mismatch-Repair Deficiency" (Dung Thi Le et al., 2015), with 9,595 citations. Next come "Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade" (6,813) and "Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies" (5,211).

Showing 50 of 61 papers. Every paper with more than 150 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 PD-1 Blockade in Tumors with Mismatch-Repair Deficiency Dung Thi Le et al. · New England Journal of Medicine Open access 30 May 2015 9,595
2 Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade Dung Thi Le et al. · Science Open access 27 Jul 2017 6,813
3 Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies Chetan Bettegowda et al. · Science Translational Medicine Open access 19 Feb 2014 5,211
4 Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma Alexandra Snyder et al. · New England Journal of Medicine Open access 20 Nov 2014 4,426
5 Neoadjuvant PD-1 Blockade in Resectable Lung Cancer Patrick M. Forde et al. · New England Journal of Medicine Open access 16 Apr 2018 2,183
6 The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers Luis Alberto Diaz, Richard Thomas Williams, Jian Wu et al. · Nature Open access Jun 2012 1,760
7 DAXX / ATRX , MEN1 , and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors Yuchen Jiao, Chanjuan Shi, Barish H. Edil et al. · Science Open access 20 Jan 2011 1,727
8 Cancer/testis antigens, gametogenesis and cancer Andrew J.G. Simpson, Otávia L. Caballero, Achim A. Jungbluth et al. · Nature reviews. Cancer Review 20 Jul 2005 1,613
9 Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer Australian Pancreatic Cancer Genome Initiative et al. · Nature Open access Nov 2017 1,242
10 Consensus guidelines for the definition, detection and interpretation of immunogenic cell death Lorenzo Galluzzi et al. · Journal for ImmunoTherapy of Cancer Open access Mar 2020 1,116
11 Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures Yasin Şenbabaoğlu et al. · Genome biology Open access 17 Nov 2016 1,056
12 Clinical implications of T cell exhaustion for cancer immunotherapy Andrew T. Chow, Karlo Perica, Christopher Austin Klebanoff et al. · Nature Reviews Clinical Oncology ReviewOpen access 10 Oct 2022 1,043
13 Enhancing immunotherapy in cancer by targeting emerging immunomodulatory pathways Lukas Kraehenbuehl, Chien‐Huan Weng, Shabnam Z Eghbali et al. · Nature Reviews Clinical Oncology Review 27 Sep 2021 903
14 Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells Olivier De Henau et al. · Nature Open access Nov 2016 893
15 Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors Shihao Xu et al. · Immunity Open access 7 Jun 2021 815
16 The head and neck cancer immune landscape and its immunotherapeutic implications Rajarsi Mandal, Yasin Şenbabaoğlu, Alexis Desrichard et al. · JCI Insight Open access 19 Oct 2016 804
17 Localized Oncolytic Virotherapy Overcomes Systemic Tumor Resistance to Immune Checkpoint Blockade Immunotherapy Dmitriy Zamarin, Rikke Holmgaard, Sumit Kumar Subudhi et al. · Science Translational Medicine Open access 5 Mar 2014 712
18 A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy Marta Łuksza, Nadeem Riaz, Vladimir Makarov et al. · Nature Open access Nov 2017 685
19 CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors Haiping Wang, Fabien Franco, Yao-Chen Tsui et al. · Nature Immunology Open access 17 Feb 2020 681
20 Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4 Rikke Holmgaard, Dmitriy Zamarin, David H. Munn et al. · The Journal of Experimental Medicine Open access 10 Jun 2013 641
21 Frequent ATRX , CIC , FUBP1 and IDH1 mutations refine the classification of malignant gliomas Yuchen Jiao et al. · Oncotarget Open access 31 Jul 2012 590
22 Genetic diversity of tumors with mismatch repair deficiency influences anti–PD-1 immunotherapy response Rajarsi Mandal et al. · Science Open access 2 May 2019 587
23 Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers Justina X. Caushi et al. · Nature Open access 21 Jul 2021 574
24 Evaluation of Ipilimumab in Combination With Allogeneic Pancreatic Tumor Cells Transfected With a GM-CSF Gene in Previously Treated Pancreatic Cancer Dung Thi Le, Eric R. Lutz, Jennifer N. Uram et al. · Journal of Immunotherapy Open access 6 Aug 2013 564
25 Concomitant Tumor Immunity to a Poorly Immunogenic Melanoma Is Prevented by Regulatory T Cells Mary Jo Turk, Jose Alejandro Guevara-Patino, Gabrielle A. Rizzuto et al. · The Journal of Experimental Medicine Open access 20 Sep 2004 541
26 Emerging Concepts for Immune Checkpoint Blockade-Based Combination Therapies Roberta Zappasodi, Taha Merghoub, Jedd D. Wolchok · Cancer Cell Open access Apr 2018 534
27 Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine Luís Felipe Campesato, Sadna Budhu, Jeremy H. Tchaicha et al. · Nature Communications Open access 11 Aug 2020 517
28 The genomic landscape of response to EGFR blockade in colorectal cancer Andrea Bertotti et al. · Nature Open access 29 Sep 2015 500
29 Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner Rikke Holmgaard, Dmitriy Zamarin, Yanyun Li et al. · Cell Reports Open access 24 Sep 2015 499
30 Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient Alejandro Jiménez-Sánchez, Danish Memon, Stephane Pourpe et al. · Cell Open access Aug 2017 474
31 CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours Roberta Zappasodi et al. · Nature Open access 15 Feb 2021 404
32 Intratumoral injection of Clostridium novyi -NT spores induces antitumor responses Nicholas Jason Roberts et al. · Science Translational Medicine Open access 13 Aug 2014 401
33 Noninvasive Early Identification of Therapeutic Benefit from Immune Checkpoint Inhibition Barzin Y. Nabet et al. · Cell Open access Oct 2020 373
34 Neutrophil phenotypes and functions in cancer: A consensus statement Daniela F. Quail et al. · The Journal of Experimental Medicine Open access 6 May 2022 364
35 ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity John Alec Moral et al. · Nature Open access 19 Feb 2020 353
36 Evaluation of DNA from the Papanicolaou Test to Detect Ovarian and Endometrial Cancers Isaac Kinde, Chetan Bettegowda, Yuxuan Wang et al. · Science Translational Medicine Open access 9 Jan 2013 327
37 T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants Daniel Hirschhorn et al. · Cell Open access Mar 2023 312
38 Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis Jun Li et al. · Cancer Discovery Open access 28 Dec 2020 301
39 Pharmacologic modulation of RNA splicing enhances anti-tumor immunity Sydney X. Lu et al. · Cell Open access 24 Jun 2021 297
40 Mismatch Repair Deficiency and Response to Immune Checkpoint Blockade Valerie Lee, Adrian Gerard Murphy, Dung Thi Le et al. · The Oncologist Open access 13 Jul 2016 284
41 Cross-presentation of Disialoganglioside GD3 to Natural Killer T Cells Dianna Wu, Neil Howard Segal, Stéphane Sidobre et al. · The Journal of Experimental Medicine Open access 7 Jul 2003 280
42 TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine Isaac Kinde, Enrico Munari, Sheila F. Faraj et al. · Cancer Research Open access 12 Oct 2013 255
43 Somatic Mutations and Neoepitope Homology in Melanomas Treated with CTLA-4 Blockade Tavi Nathanson, Arun Kumar Ahuja, Alex Rubinsteyn et al. · Cancer Immunology Research Open access 12 Dec 2016 246
44 Rational design of anti-GITR-based combination immunotherapy Roberta Zappasodi, Cynthia A. Sirard, Yanyun Li et al. · Nature Medicine Open access 29 Apr 2019 233
45 Tumor immunity and autoimmunity induced by immunization with homologous DNA. Lawrence W. Weber, Wilbur Bo Bowne, Jedd D. Wolchok et al. · Journal of Clinical Investigation Open access 15 Sep 1998 230
46 Classification and Subtype Prediction of Adult Soft Tissue Sarcoma by Functional Genomics Neil Howard Segal, Paul Pavlidis, Cristina R. Antonescu et al. · American Journal Of Pathology Open access Aug 2003 224
47 Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade Evan J. Lipson, Victor E. Velculescu, Theresa S. Pritchard et al. · Journal for ImmunoTherapy of Cancer Open access Dec 2014 218
48 Neoantigen quality predicts immunoediting in survivors of pancreatic cancer Marta Łuksza et al. · Nature Open access 19 May 2022 211
49 Heteroclitic Immunization Induces Tumor Immunity Ruben Dyall, Wilbur Bo Bowne, Lawrence W. Weber et al. · The Journal of Experimental Medicine Open access 2 Nov 1998 205
50 Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer Danish Memon et al. · Cancer Cell Open access 11 Jan 2024 203

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.