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Genetic studies of body mass index yield new insights for obesity biology
The LifeLines Cohort Study et al. · Nature
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10 Feb 2015 |
4,954 |
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Discovery and refinement of loci associated with lipid levels
Cristen J. Willer et al. · Nature Genetics
Open access259 authors |
6 Oct 2013 |
3,319 |
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A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
Majid Nikpay et al. · Nature Genetics
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7 Sep 2015 |
2,733 |
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Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
Cardiogenics et al. · Nature Genetics
Open access167 authors |
6 Mar 2011 |
1,959 |
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New genetic loci link adipose and insulin biology to body fat distribution
Dmitry Shungin et al. · Nature
Open access410 authors |
10 Feb 2015 |
1,726 |
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Large-scale association analysis identifies new risk loci for coronary artery disease
Panos Deloukas et al. · Nature Genetics
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2 Dec 2012 |
1,681 |
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Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management
Erik S.G. Stroes et al. · European Heart Journal
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18 Feb 2015 |
1,451 |
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The UK10K project identifies rare variants in health and disease
Writing group et al. · Nature
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14 Sep 2015 |
1,195 |
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The power of genetic diversity in genome-wide association studies of lipids
Sarah E. Graham et al. · Nature
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9 Dec 2021 |
1,099 |
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Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts
Karani Santhanakrishnan Vimaleswaran et al. · PLoS Medicine
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5 Feb 2013 |
1,069 |
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A catalog of genetic loci associated with kidney function from analyses of a million individuals
Lifelines Cohort Study et al. · Nature Genetics
Open access329 authors |
31 May 2019 |
946 |
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Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure
Sonia H Shah et al. · Nature Communications
Open access203 authors |
9 Jan 2020 |
944 |
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A saturated map of common genetic variants associated with human height
Loïc Yengo et al. · Nature
Open access632 authors |
12 Oct 2022 |
934 |
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The trans-ancestral genomic architecture of glycemic traits
Jihua Chen et al. · Nature Genetics
Open access417 authors |
31 May 2021 |
918 |
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Common variants associated with plasma triglycerides and risk for coronary artery disease
Ron Do et al. · Nature Genetics
Open access263 authors |
6 Oct 2013 |
912 |
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Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
LifeLines Cohort Study et al. · Nature Genetics
Open access226 authors |
21 Dec 2012 |
893 |
| 17 |
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Robert A. Scott et al. · Nature Genetics
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12 Aug 2012 |
859 |
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Multi-ethnic genome-wide association study for atrial fibrillation
Carolina Roselli et al. · Nature Genetics
Open access218 authors |
8 Jun 2018 |
836 |
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Association analyses based on false discovery rate implicate new loci for coronary artery disease
Christopher P. Nelson et al. · Nature Genetics
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17 Jul 2017 |
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Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report
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30 Apr 2019 |
713 |
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Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol
Reijo Laaksonen et al. · European Heart Journal
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28 Apr 2016 |
704 |
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Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Sonja I. Berndt et al. · Nature Genetics
Open access322 authors |
7 Apr 2013 |
688 |
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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
Ron Do et al. · Nature
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8 Dec 2014 |
685 |
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Association of Vitamin D Deficiency with Heart Failure and Sudden Cardiac Death in a Large Cross-Sectional Study of Patients Referred for Coronary Angiography
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Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
Cristian Pattaro et al. · Nature Communications
Open access700 authors |
21 Jan 2016 |
547 |
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Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease
Helena Gylling et al. · Atherosclerosis
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23 Nov 2013 |
527 |
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New susceptibility locus for coronary artery disease on chromosome 3q22.3
Italian Atherosclerosis, Thrombosis, and Vascular Biology Working Group et al. · Nature Genetics
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8 Feb 2009 |
488 |
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Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
Joshua C. Randall et al. · PLoS Genetics
Open access265 authors |
6 Jun 2013 |
462 |
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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
Symen Ligthart et al. · The American Journal of Human Genetics
Open access349 authors |
Nov 2018 |
461 |
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Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
Eleanor Wheeler et al. · PLoS Medicine
Open access216 authors |
12 Sep 2017 |
450 |
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The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Georg Ehret et al. · Nature Genetics
Open access313 authors |
12 Sep 2016 |
446 |
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Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
German Chronic Kidney Disease Study et al. · Nature Genetics
Open access228 authors |
Oct 2019 |
442 |
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Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
Xia Jiang et al. · Nature Communications
Open access104 authors |
11 Jan 2018 |
408 |
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Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
Jie Huang et al. · Nature Communications
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14 Sep 2015 |
387 |
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Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study
Karani Santhanakrishnan Vimaleswaran et al. · The Lancet Diabetes & Endocrinology
Open access103 authors |
25 Jun 2014 |
382 |
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Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
Norihiro Kato et al. · Nature Genetics
Open access248 authors |
21 Sep 2015 |
381 |
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Genetic evidence of assortative mating in humans
Matthew R. Robinson et al. · Nature Human Behaviour
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371 |
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Rationale and Plan for Vitamin D Food Fortification: A Review and Guidance Paper
Stefan Pilz et al. · Frontiers in Endocrinology
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17 Jul 2018 |
367 |
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Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation
Ingrid Elisabeth Christophersen et al. · Nature Genetics
Open access162 authors |
17 Apr 2017 |
365 |
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Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium
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16 Feb 2017 |
355 |
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Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
Mariaelisa Graff et al. · PLoS Genetics
ReviewOpen access281 authors |
27 Apr 2017 |
345 |
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Seventy-five genetic loci influencing the human red blood cell
Pim van der Harst et al. · Nature
Open access195 authors |
Dec 2012 |
336 |
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Vitamin D and cardiovascular disease prevention
Stefan Pilz, Nicolas Verheyen, Martin Robert Grübler et al. · Nature Reviews Cardiology
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6 May 2016 |
330 |
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The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis
Timothy M Walker et al. · The Lancet Microbe
Open access232 authors |
8 Mar 2022 |
305 |
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Uric Acid and Cardiovascular Events
Marcus Edi Kleber, Graciela Delgado, Tanja B. Grammer et al. · Journal of the American Society of Nephrology
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18 Mar 2015 |
302 |
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HDL cholesterol: reappraisal of its clinical relevance
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24 Mar 2017 |
292 |
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Genome-wide analysis identifies novel susceptibility loci for myocardial infarction
Jaana Hartiala et al. · European Heart Journal
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8 Dec 2020 |
290 |
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Dysfunctional nitric oxide signalling increases risk of myocardial infarction
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Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation
Stephen Zewinger et al. · Nature Immunology
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282 |
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Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci
Folkert Wouter Asselbergs et al. · The American Journal of Human Genetics
Open access170 authors |
11 Oct 2012 |
274 |