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Institution · Synovo (Germany)

Most cited papers from Synovo (Germany)

What are the most cited papers from Synovo (Germany)?

The most cited paper from Synovo (Germany) is "The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction" (Philipp Schwabl, Eva Hambruch, Berit Seeland et al., 2016), with 176 citations. Next come "Quorum-Quenching and Matrix-Degrading Enzymes in Multilayer Coatings Synergistically Prevent Bacterial Biofilm Formation on Urinary Catheters" (159) and "Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion" (128).

Showing 50 of 56 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The FXR agonist PX20606 ameliorates portal hypertension by targeting vascular remodelling and sinusoidal dysfunction Philipp Schwabl, Eva Hambruch, Berit Seeland et al. · Journal of Hepatology Open access 18 Dec 2016 176
2 Quorum-Quenching and Matrix-Degrading Enzymes in Multilayer Coatings Synergistically Prevent Bacterial Biofilm Formation on Urinary Catheters Kristina Ivanova, Margarida M. Fernandes, António Francesko et al. · ACS Applied Materials & Interfaces Open access 23 Nov 2015 159
3 Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion Florian C. Maier, Hans F. Wehrl, Andreas M. Schmid et al. · Nature Medicine 10 Nov 2014 128
4 Synthetic Farnesoid X Receptor Agonists Induce High-Density Lipoprotein-Mediated Transhepatic Cholesterol Efflux in Mice and Monkeys and Prevent Atherosclerosis in Cholesteryl Ester Transfer Protein Transgenic Low-Density Lipoprotein Receptor (−/−) Mice Eva Hambruch, Shinobu Miyazaki‐Anzai, Ulrike K. Hahn et al. · Journal of Pharmacology and Experimental Therapeutics Open access 24 Aug 2012 99
5 Elevated wound fluid pH correlates with increased risk of wound infection Daniel Gary Metcalf, Marieke Haalboom, Philip G. Bowler et al. · Wound Medicine 24 Jul 2019 82
6 Dexamethasone attenuates early expression of three molecules associated with microglia/macrophages activation following rat traumatic brain injury Zhiyuan Zhang, Zhiren Zhang, Zhiren Zhang et al. · Acta Neuropathologica 31 Jan 2007 76
7 The Non-Steroidal FXR Agonist Cilofexor Improves Portal Hypertension and Reduces Hepatic Fibrosis in a Rat NASH Model Philipp Schwabl, Eva Hambruch, Grant R. Budas et al. · Biomedicines Open access 9 Jan 2021 69
8 Early infiltration of CD8+ macrophages/microglia to lesions of rat traumatic brain injury Zhiren Zhang, Matthias Artelt, Michael W. M. Burnet et al. · Neuroscience 2006 61
9 Synthesis and pharmacological validation of a novel series of non-steroidal FXR agonists Ulrich R. Abel, Thomas Schlüter, Andreas Schulz et al. · Bioorganic & Medicinal Chemistry Letters Open access 20 Jun 2010 60
10 Development of non-antibiotic macrolide that corrects inflammation-driven immune dysfunction in models of inflammatory bowel diseases and arthritis Andrea Mencarelli, Eleonora Distrutti, Barbara Renga et al. · European Journal of Pharmacology 30 Apr 2011 59
11 Enhancing Methotrexate Tolerance with Folate Tagged Liposomes in Arthritic Mice Eugénia Nogueira, Franck Lager, Delphine Le Roux et al. · Journal of Biomedical Nanotechnology Open access 30 Jul 2015 58
12 Lesional accumulation of P2X4 receptor+ monocytes following experimental traumatic brain injury Zhiren Zhang, Matthias Artelt, Michael W. M. Burnet et al. · Experimental Neurology 3 Nov 2005 57
13 pH-responsive materials for optical monitoring of wound status Clemens Gamerith, Daniel Luschnig, Andreas Ortner et al. · Sensors and Actuators B Chemical 9 Aug 2019 55
14 Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa Thomas E. Blank, Tobias Goldmann, Mirja Koch et al. · Frontiers in Immunology Open access 4 Jan 2018 55
15 Cellobiose dehydrogenase functionalized urinary catheter as novel antibiofilm system Barbara Thallinger, Martin Brandauer, Peter Burger et al. · Journal of Biomedical Materials Research Part B Applied Biomaterials 6 Aug 2015 44
16 Azithromycin analogue CSY 0073 attenuates lung inflammation induced by LPS challenge Viviane Balloy, April E. Deveaux, David Lebeaux et al. · British Journal of Pharmacology Open access 13 Jan 2014 43
17 Culture results from wound biopsy versus wound swab: does it matter for the assessment of wound infection? Marieke Haalboom, Miriam H.E. Blokhuis‐Arkes, Roland J. Beuk et al. · Clinical Microbiology and Infection Open access 23 Aug 2018 40
18 FTY720 attenuates accumulation of EMAP‐II+ and MHC‐II+ monocytes in early lesions of rat traumatic brain injury Zhiyuan Zhang, Zhiyuan Zhang, Zhiren Zhang et al. · Journal of Cellular and Molecular Medicine Open access Mar 2007 40
19 Structural changes within the bifunctional cryptochrome/photolyase CraCRY upon blue light excitation Sophie Franz-Badur, Alexander Penner, Simon Straß et al. · Scientific Reports Open access 9 Jul 2019 33
20 Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties Olaf D. Kinzel, Christoph Steeneck, Thomas Schlüter et al. · Bioorganic & Medicinal Chemistry Letters Open access 24 May 2016 32
21 Penetration, distribution, and elimination of remofuscin/soraprazan in Stargardt mouse eyes following a single intravitreal injection using pharmacokinetics and transmission electron microscopic autoradiography: Implication for the local treatment of Stargardt’s disease and dry age‐related macular degeneration Sylvie Julien, Barbara Illing, Alexander Tschulakow et al. · Pharmacology Research & Perspectives Open access 8 Nov 2020 26
22 AWD-12-281 (inhaled) (elbion/GlaxoSmithKline). Hans-Jürgen Gutke, Jan‐Hinrich Guse, Moussa Khobzaoui et al. · PubMed Nov 2005 23
23 Mechanistic role of p38 MAPK in gastric cancer dissemination in a rodent model peritoneal metastasis Luigina Graziosi, Andrea Mencarelli, Chiara Santorelli et al. · European Journal of Pharmacology 20 Nov 2011 23
24 A potassium channel agonist protects hearing function and promotes outer hair cell survival in a mouse model for age-related hearing loss Barbara Peixoto Pinheiro, Marcus Müller, Michael Bös et al. · Cell Death and Disease Open access 11 Jul 2022 21
25 Removal of RPE lipofuscin results in rescue from retinal degeneration in a mouse model of advanced Stargardt disease: Role of reactive oxygen species Yuan Fang, Tatjana Taubitz, Alexander Tschulakow et al. · Free Radical Biology and Medicine Open access 24 Feb 2022 21
26 The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine‐rich glycoprotein Ulrich Deuschle, Manfred Birkel, Eva Hambruch et al. · International Journal of Cancer Open access Nov 2014 19
27 Low Prevalence of Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions—A Multiregional Study in Central and West Africa Tina Krueger, Moses Ikegbunam, Abel Lissom et al. · Pathogens Open access 14 Mar 2023 18
28 Bone morphogenetic protein-6 is expressed early by activated astrocytes in lesions of rat traumatic brain injury Zhiren Zhang, Katrin Trautmann, Matthias Artelt et al. · Neuroscience 2006 17
29 A Connection between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis Vukić Šoškić, Martina Klemm, Tassula Proikas‐Cezanne et al. · Journal of Proteome Research 9 May 2008 16
30 Design and Synthesis of Highly Selective Brain Penetrant p38α Mitogen-Activated Protein Kinase Inhibitors Niklas M. Tormählen, Mariella Martorelli, Annette Kühn et al. · Journal of Medicinal Chemistry Open access 11 May 2021 15
31 Lysozyme‐responsive polymer systems for detection of infection Doris Schiffer, Vanessa Verient, Daniel Luschnig et al. · Engineering in Life Sciences 12 Jan 2015 15
32 Imidazoquinolines with improved pharmacokinetic properties induce a high IFNα to TNFα ratio in vitro and in vivo Manuel Keppler, Simon Straß, Sophia Geiger et al. · Frontiers in Immunology Open access 20 Jun 2023 14
33 Pharmacokinetics, Pharmacodynamics and Antiviral Efficacy of the MEK Inhibitor Zapnometinib in Animal Models and in Humans Julia Koch-Heier, Annika Schönsiegel, Lara Maria Waidele et al. · Frontiers in Pharmacology Open access 15 Jun 2022 14
34 Folate-Targeted Liposomal Formulations Improve Effects of Methotrexate in Murine Collagen-Induced Arthritis Diana Guimarães, Franck Lager, Gilles Renault et al. · Biomedicines Open access 21 Jan 2022 14
35 Intramolecular sulfoxide electrophilic sulfenylation in 2- and 3-indoleanilides Mary E. Eggers, Parag V. Jog, Dallas K. Bates · Tetrahedron 24 Oct 2007 13
36 Dexamethasone transiently attenuates up-regulation of endostatin/collagen XVIII following traumatic brain injury Zhiyuan Zhang, Zhiyuan Zhang, Zhiren Zhang et al. · Neuroscience 8 Jun 2007 13
37 Complementary methods for SARS-CoV-2 diagnosis in times of material shortage Thaisa Lucas Sandri, Juliana Inoue, Johanna Geiger et al. · Scientific Reports Open access 7 Jun 2021 11
38 A Host-Directed Approach to the Detection of Infection in Hard-to-Heal Wounds Michael W. M. Burnet, Daniel Gary Metcalf, Scarlet Milo et al. · Diagnostics Open access 4 Oct 2022 8
39 Inhibition of Sema-3A Promotes Cell Migration, Axonal Growth, and Retinal Ganglion Cell Survival Anat Nitzan, Miriam Corredor-Sanchez, Ronit Galron et al. · Translational Vision Science & Technology Open access 24 Nov 2021 8
40 Efficacy of Bioactive Cyclic Peptides in Rheumatoid Arthritis: Translation from In Vitro to In Vivo Models Roger R. C. New, Michal Bogus, Gurpal S. Bansal et al. · Molecules Open access 25 Sep 2017 8
41 Isostearic acid is an active component of imiquimod formulations used to induce psoriaform disease models Simon Straß, Johanna Geiger, Mariella Martorelli et al. · Inflammopharmacology 21 Mar 2023 7
42 Synthesis, Characterization, and in vivo Distribution of Intracellular Delivered Macrolide Short‐Chain Fatty Acid Derivatives Simon Straß, Anna Schwamborn, Manuel Keppler et al. · ChemMedChem 31 Mar 2021 7
43 The Azithromycin Pro-Drug CSY5669 Boosts Bacterial Killing While Attenuating Lung Inflammation Associated with Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus Anno Saris, Wanhai Qin, Christine C. A. van Linge et al. · Antimicrobial Agents and Chemotherapy Open access 16 Aug 2022 6
44 Pharmacokinetic Optimization of Small Molecule Janus Kinase 3 Inhibitors to Target Immune Cells Julian Laux, Michael Förster, Laura Riexinger et al. · ACS Pharmacology & Translational Science Open access 14 Jul 2022 6
45 Evaluating Malaria Rapid Diagnostic Tests and Microscopy for Detecting Plasmodium Infection and Status of Plasmodium falciparum Histidine-Rich Protein 2/3 Gene Deletions in Southeastern Nigeria Moses Ikegbunam, Maike Maurer, Harrison Odera Abone et al. · American Journal of Tropical Medicine and Hygiene Open access 26 Mar 2024 5
46 Immune cell targeted fumaric esters support a role of GPR109A as a primary target of monomethyl fumarate in vivo Simon Straß, Johanna Geiger, Natascha Cloos et al. · Inflammopharmacology Apr 2023 5
47 Anti-Inflammatory Macrolides to Manage Chronic Neutrophilic Inflammation Michael W. M. Burnet, Jan‐Hinrich Guse, Hans-Jürgen Gutke et al. · Royal Society of Chemistry eBooks Book chapter 3 Oct 2014 5
48 Glucagon-like peptide-1 receptor agonists for treatment of diabetes and obesity: advantage of oral delivery Roger R. C. New, M. Bogus, G. N. Travers et al. · Frontiers in Drug Delivery Open access 6 Nov 2024 3
49 Selective Inhibitors of Janus Kinase 3 Modify Responses to Lipopolysaccharides by Increasing the Interleukin-10-to-Tumor Necrosis Factor α Ratio Julian Laux, Mariella Martorelli, Nadja Späth et al. · ACS Pharmacology & Translational Science Open access 18 May 2023 3
50 99 NOVEL FXR AGONISTS WITH POTENT LIPID LOWERING, INSULIN SENSITISING, ANTI-INFLAMMATORY AND ANTI-FIBROTISATION EFFECTS IN MOUSE MODELS OF METABOLIC SYNDROME AND NASH Claus Kremoser, Eva Hambruch, Ulrich Deuschle et al. · Journal of Hepatology Mar 2011 3

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.