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Institution · Syntrix Biosystems (United States)

Most cited papers from Syntrix Biosystems (United States)

Syntrix Biosystems (United States)

What are the most cited papers from Syntrix Biosystems (United States)?

The most cited paper from Syntrix Biosystems (United States) is "Binding of perfluorinated fatty acids to serum proteins" (Paul D. Jones, Wenyue Hu, Wim De Coen et al., 2003), with 638 citations. Next come "KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer" (632) and "Effective combinatorial immunotherapy for castration-resistant prostate cancer" (555).

Showing 50 of 94 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Binding of perfluorinated fatty acids to serum proteins Paul D. Jones, Wenyue Hu, Wim De Coen et al. · Environmental Toxicology and Chemistry Nov 2003 638
2 KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer Wenting Liao et al. · Cancer Cell Open access 21 Mar 2019 632
3 Effective combinatorial immunotherapy for castration-resistant prostate cancer Xin Lü, James W. Horner, Erin Paul et al. · Nature Open access 16 Mar 2017 555
4 Aquatic Toxicology of Perfluorinated Chemicals John Paul Giesy, Jonathan E. Naile, Jong Seong Khim et al. · Reviews of Environmental Contamination and Toxicology Book chapter 6 Nov 2009 285
5 Inhibition of MDSC Trafficking with SX-682, a CXCR1/2 Inhibitor, Enhances NK-Cell Immunotherapy in Head and Neck Cancer Models Sarah Greene, Yvette L. Robbins, Wojciech K. Mydlarz et al. · Clinical Cancer Research Open access 17 Dec 2019 284
6 Inhibiting myeloid-derived suppressor cell trafficking enhances T cell immunotherapy Lillian Sun, Paúl E. Clavijo, Yvette L. Robbins et al. · JCI Insight Open access 3 Apr 2019 241
7 Ecotoxicological Evaluation of Perfluorooctanesulfonate (PFOS) Susan A. Beach, John L. Newsted, Katie K. Coady et al. · Reviews of Environmental Contamination and Toxicology Book chapter 2006 232
8 Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC Julia Kargl, Xiaodong Zhu, Huajia Zhang et al. · JCI Insight Open access 18 Dec 2019 199
9 Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: Hormone production Markus Hecker, John L. Newsted, Margaret Burkhardt Murphy et al. · Toxicology and Applied Pharmacology Aug 2006 198
10 Perfluorinated compounds in streams of the Shihwa industrial zone and Lake Shihwa, South Korea Paweł Rostkowski, Nobuyoshi Yamashita, Iris Man Ka So et al. · Environmental Toxicology and Chemistry 31 Aug 2006 164
11 Avian Toxicity Reference Values for Perfluorooctane Sulfonate John L. Newsted, Paul D. Jones, Katie K. Coady et al. · Environmental Science & Technology 14 Oct 2005 161
12 Interactions between aryl hydrocarbon receptor (AhR) and hypoxia signaling pathways Minghua Nie, Alan L. Blankenship, John Paul Giesy · Environmental Toxicology and Pharmacology Jun 2001 110
13 Effects of perfluorooctane sulfonate on mallard and northern bobwhite quail exposed chronically via the diet John L. Newsted, Katherine Kemler Coady, Susan A. Beach et al. · Environmental Toxicology and Pharmacology 5 Jun 2006 109
14 Combined Inhibition of SHP2 and CXCR1/2 Promotes Antitumor T-cell Response in NSCLC Kwan Ho Tang, Shuai Li, Alireza Khodadadi-Jamayran et al. · Cancer Discovery Open access 5 Aug 2021 105
15 The H295R system for evaluation of endocrine-disrupting effects Tannia Gracia, Klára Hilscherová, Paul D. Jones et al. · Ecotoxicology and Environmental Safety 29 Aug 2006 100
16 Simultaneous inhibition of CXCR1/2, TGF-β, and PD-L1 remodels the tumor and its microenvironment to drive antitumor immunity Lucas A. Horn, Jeffrey Riskin, Heidi Hempel et al. · Journal for ImmunoTherapy of Cancer Open access Mar 2020 99
17 The OECD validation program of the H295R steroidogenesis assay: Phase 3. Final inter-laboratory validation study Markus Hecker, Henner Hollert, Ralph L. Cooper et al. · Environmental Science and Pollution Research 2 Oct 2010 97
18 Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer Pat Gulhati et al. · Nature Cancer Open access 30 Dec 2022 90
19 Acute and Chronic Effects of Perfluorobutane Sulfonate (PFBS) on the Mallard and Northern Bobwhite Quail John L. Newsted, Susan A. Beach, Sean Gallagher et al. · Archives of Environmental Contamination and Toxicology 4 Oct 2007 89
20 Comparison of fathead minnow ovary explant and H295R cell-based steroidogenesis assays for identifying endocrine-active chemicals Daniel L. Villeneuve, Gerald T. Ankley, Elizabeth A. Makynen et al. · Ecotoxicology and Environmental Safety 21 Apr 2007 76
21 The OECD Validation Program of the H295R Steroidogenesis Assay for the Identification of In Vitro Inhibitors and Inducers of Testosterone and Estradiol Production. Phase 2: Inter-Laboratory Pre-Validation Studies (8 pp) Markus Hecker, Henner Hollert, Ralph L. Cooper et al. · Environmental Science and Pollution Research 2007 74
22 Modulation of steroidogenic gene expression and hormone production of H295R cells by pharmaceuticals and other environmentally active compounds Tannia Gracia, Klára Hilscherová, Paul D. Jones et al. · Toxicology and Applied Pharmacology 4 Aug 2007 74
23 Assessment of chemical effects on aromatase activity using the H295R cell line Eric B. Higley, John L. Newsted, Xiaowei Zhang et al. · Environmental Science and Pollution Research 19 Jan 2010 73
24 Mechanisms of TCDD-induced abnormalities and embryo lethality in white leghorn chickens Anneka Blankenship, Klára Hilscherová, Minghua Nie et al. · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology Sep 2003 66
25 Sensitivity of Japanese Quail (Coturnix japonica), Common Pheasant (Phasianus colchicus), and White Leghorn Chicken (Gallus gallus domesticus) Embryos to In Ovo Exposure to TCDD, PeCDF, and TCDF Andrew M. Cohen-Barnhouse, Matthew J. Zwiernik, Jane E. Link et al. · Toxicological Sciences 22 Sep 2010 53
26 Oxidative stress in liver and brain of the hatchling chicken (Gallus domesticus) following in ovo injection with TCDD Klára Hilscherová, Anneka Blankenship, Minghua Nie et al. · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology Sep 2003 48
27 Modulation of steroidogenesis by coastal waters and sewage effluents of Hong Kong, China, using the H295R assay Tannia Gracia, Paul D. Jones, Eric B. Higley et al. · Environmental Science and Pollution Research 20 May 2008 46
28 Bioaccumulation of polychlorinated dibenzo-p-dioxins, dibenzofurans, and dioxin-like polychlorinated biphenyls in fishes from the Tittabawassee and Saginaw Rivers, Michigan, USA Yi Wan, Paul D. Jones, Ryan R. Holem et al. · The Science of The Total Environment 10 Mar 2010 43
29 Alteration of steroidogenesis in H295R cells by organic sediment contaminants and relationships to other endocrine disrupting effects Luděk Bláha, Klára Hilscherová, Edita Mazurová et al. · Environment International 5 May 2006 39
30 Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2 Dean Y. Maeda, Angela M. Peck, Aaron D. Schuler et al. · Journal of Medicinal Chemistry Open access 25 Sep 2014 38
31 Perfluorinated Compounds in the Great Lakes John Paul Giesy, Scott A. Mabury, Jonathan W. Martin et al. · ˜The œhandbook of environmental chemistry Book chapter 10 Jan 2006 34
32 IL-8 signaling does not mediate intra-amniotic LPS-induced inflammation and maturation in preterm fetal lamb lung Suhas G. Kallapur, Timothy J. M. Moss, Richard Lambert Auten et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology Open access 3 Jul 2009 34
33 Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer Yini Zhu et al. · Science Immunology Open access 10 Mar 2023 33
34 Effects of repeated exposure to malathion on growth, food consumption, and locomotor performance of the western fence lizard (Sceloporus occidentalis) Ryan R. Holem, William Alexander Hopkins, Larry G. Talent · Environmental Pollution 5 Jul 2007 33
35 Tree swallow (Tachycineta bicolor) exposure to polychlorinated biphenyls at the Kalamazoo River superfund site, Michigan, USA Arianne M. Neigh, Matthew J. Zwiernik, Patrick W. Bradley et al. · Environmental Toxicology and Chemistry 17 Jan 2006 32
36 Protein kinase A catalytic subunit interacts and phosphorylates members of trans-sialidase super-family in Trypanosoma cruzi Yi Bao, Louis M. Weiss, Fen Yan et al. · Microbes and Infection Open access 12 May 2010 28
37 Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology Marialuisa Moccia, Brendan Frett, Lingtian Zhang et al. · Journal of Medicinal Chemistry Open access 16 Apr 2020 27
38 Squamous epithelial lesion of the mandibles and maxillae of wild mink (Mustela vison) naturally exposed to polychlorinated biphenyls Kerrie J. Beckett, Stephanie D. Millsap, Alan L. Blankenship et al. · Environmental Toxicology and Chemistry Mar 2005 26
39 Optimization of Bivalent Glutathione S-Transferase Inhibitors by Combinatorial Linker Design Sumit S. Mahajan, Liming Hou, Catalin E. Doneanu et al. · Journal of the American Chemical Society 10 Jun 2006 26
40 Passerine Exposure to Primarily PCDFs and PCDDs in the River Floodplains Near Midland, Michigan, USA Timothy B. Fredricks, Matthew J. Zwiernik, Rita M. Seston et al. · Archives of Environmental Contamination and Toxicology Open access 5 Nov 2009 25
41 Glutathione S-transferase P1-1 expression modulates sensitivity of human kidney 293 cells to photodynamic therapy with hypericin Michael J. Dabrowski, Dean Y. Maeda, John A. Zebala et al. · Archives of Biochemistry and Biophysics Open access 4 Mar 2006 24
42 Regression and Eradication of Triple-Negative Breast Carcinoma in 4T1 Mouse Model by Combination Immunotherapies Saifun Nahar, Yue Huang, Bethany A. Nagy et al. · Cancers Open access 19 Apr 2023 23
43 Intestinal Transport of Aminopterin Enantiomers in Dogs and Humans with Psoriasis Is Stereoselective: Evidence for a Mechanism Involving the Proton-Coupled Folate Transporter Alan Menter, Breck Thrash, Christina Cherian et al. · Journal of Pharmacology and Experimental Therapeutics Open access Jun 2012 23
44 Bivalent inhibitors of glutathione S-transferase: The effect of spacer length on isozyme selectivity Dean Y. Maeda, Sumit S. Mahajan, William M. Atkins et al. · Bioorganic & Medicinal Chemistry Letters Open access 6 May 2006 22
45 Effects of in ovo exposure of white leghorn chicken, common pheasant, and Japanese quail to 2,3,7,8-tetrachlorodibenzo-p-dioxin and two chlorinated dibenzofurans on CYP1A induction Yinfei Yang, Steve B. Wiseman, Andrew M. Cohen-Barnhouse et al. · Environmental Toxicology and Chemistry Open access 12 Apr 2010 22
46 Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast Vidya C. Sinha, Amanda L. Rinkenbaugh, Mingchu Xu et al. · Nature Communications Open access 18 Aug 2021 21
47 Exposure and effects assessment of resident mink (Mustela vison) exposed to polychlorinated dibenzofurans and other dioxin-like compounds in the Tittabawassee River basin, Midland, Michigan, USA Matthew J. Zwiernik, Denise P. Kay, Jeremy N. Moore et al. · Environmental Toxicology and Chemistry 24 Apr 2008 21
48 Plasma to egg conversion factor for evaluating polychlorinated biphenyl and DDT exposures in great horned owls and bald eagles Karl D. Strause, Matthew J. Zwiernik, Sook Hyeon Im et al. · Environmental Toxicology and Chemistry 28 Jun 2007 20
49 CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth Jinming Yang, Kensey N. Bergdorf, Chunhua Yan et al. · Molecular Cancer Open access 3 Jun 2023 19
50 Reproductive success of passerines exposed to polychlorinated biphenyls through the terrestrial food web of the Kalamazoo River Arianne M. Neigh, Matthew J. Zwiernik, Carrie A. Joldersma et al. · Ecotoxicology and Environmental Safety 16 Dec 2005 19

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.