| 1 |
MET Exon 14 Mutations in Non–Small-Cell Lung Cancer Are Associated With Advanced Age and Stage-Dependent MET Genomic Amplification and c-Met Overexpression
Mark Magdi Awad, Geoffrey R. Oxnard, David Michael Jackman et al. · Journal of Clinical Oncology
Open access |
5 Jan 2016 |
706 |
| 2 |
Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment
Maria Pia Morelli, Michael James Overman, Arvind N. Dasari et al. · Annals of Oncology
Open access |
28 Jan 2015 |
256 |
| 3 |
Performance of Streck cfDNA Blood Collection Tubes for Liquid Biopsy Testing
Inga Medina Diaz, Annette Nocon, Daniel H. Mehnert et al. · PLoS ONE
Open access |
10 Nov 2016 |
198 |
| 4 |
Reference intervals: the way forward
Ferruccio Ceriotti, Rolf Hinzmann, Mauro Panteghini · Annals of Clinical Biochemistry International Journal of Laboratory Medicine
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22 Dec 2008 |
198 |
| 5 |
Repeated mutKRAS ctDNA measurements represent a novel and promising tool for early response prediction and therapy monitoring in advanced pancreatic cancer
Stephan Krüger, Volker Heinemann, C. M. D. Ross et al. · Annals of Oncology
Open access |
19 Sep 2018 |
164 |
| 6 |
Revisiting the white blood cell count: immature granulocytes count as a diagnostic marker to discriminate between SIRS and sepsis - a prospective, observational study
Axel Nierhaus, Stefanie Klatte, Jo Linssen et al. · BMC Immunology
Open access |
11 Feb 2013 |
137 |
| 7 |
Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies
Filip Jankú et al. · Oncotarget
Open access |
25 Feb 2015 |
94 |
| 8 |
Performance evaluation and relevance of the CellaVision TM DM96 system in routine analysis and in patients with malignant hematological diseases
Édouard Cornet, J.‐P. PEROL, Xavier Troussard · International Journal of Laboratory Hematology
Open access |
29 Oct 2008 |
78 |
| 9 |
A novel haemocytometric COVID-19 prognostic score developed and validated in an observational multicentre European hospital-based study
Joachim Linssen et al. · eLife
Open access |
26 Nov 2020 |
59 |
| 10 |
Detection of TP53 and PIK3CA Mutations in Circulating Tumor DNA Using Next-Generation Sequencing in the Screening Process for Early Breast Cancer Diagnosis
Begoña Jiménez Rodríguez, Gema Díaz Córdoba, Alicia Garrido Aranda et al. · Journal of Clinical Medicine
Open access |
7 Aug 2019 |
59 |
| 11 |
Identification and quantification of high fluorescence‐stained lymphocytes as antibody synthesizing/secreting cells using the automated routine hematology analyzer XE‐2100
Joachim Linssen, V. Jennissen, Jörg Hildmann et al. · Cytometry Part B Clinical Cytometry
|
31 Jan 2007 |
53 |
| 12 |
Pre-Analytical Evaluation of Streck Cell-Free DNA Blood Collection Tubes for Liquid Profiling in Oncology
Inga Medina Diaz, Annette Nocon, Stefanie AE Held et al. · Diagnostics
Open access |
29 Mar 2023 |
52 |
| 13 |
Reference intervals for Sysmex XN hematological parameters as assessed in the Dutch Lifelines cohort
Lucas Joost Van Pelt, Stefanie Klatte, Talent Hwandih et al. · Clinical Chemistry and Laboratory Medicine (CCLM)
Open access |
30 Apr 2022 |
48 |
| 14 |
Improved Flagging Rates on the Sysmex XE-5000 Compared With the XE-2100 Reduce the Number of Manual Film Reviews and Increase Laboratory Productivity
Carol J. Briggs, Joachim Linssen, Ian Longair et al. · American Journal of Clinical Pathology
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14 Jul 2011 |
48 |
| 15 |
Where is laboratory medicine headed in the next decade? Partnership model for efficient integration and adoption of artificial intelligence into medical laboratories
Anna Carobene, Federico Cabitza, Sergio Bernardini et al. · Clinical Chemistry and Laboratory Medicine (CCLM)
Open access |
3 Nov 2022 |
39 |
| 16 |
Efficacy of Advanced Discriminating Algorithms for Screening on Iron-Deficiency Anemia and β-Thalassemia Trait
Margreet Schoorl, Marianne Schoorl, Jo Linssen et al. · American Journal of Clinical Pathology
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Aug 2012 |
39 |
| 17 |
Automation and validation of a rapid method to assess neutrophil and monocyte activation by routine fluorescence flow cytometry in vitro
Jo Linssen, S. Aderhold, Axel Nierhaus et al. · Cytometry Part B Clinical Cytometry
Open access |
22 Apr 2008 |
39 |
| 18 |
The 2000HIV study: Design, multi-omics methods and participant characteristics
Wilhelm A. J. W. Vos et al. · Frontiers in Immunology
Open access |
20 Dec 2022 |
35 |
| 19 |
Bacteriuria and phenotypic antimicrobial susceptibility testing in 45 min by point-of-care Sysmex PA-100 System: first clinical evaluation
Carles Alonso-Tarrés, Carla Benjumea Moreno, Ferrán Navarro et al. · European Journal of Clinical Microbiology & Infectious Diseases
Open access |
3 Jun 2024 |
32 |
| 20 |
Type 1 inflammatory endotype relates to low compliance, lung fibrosis, and severe complications in COVID-19
Takehiro Hasegawa, Atsushi Nakagawa, Kohjin Suzuki et al. · Cytokine
Open access |
7 Jun 2021 |
32 |
| 21 |
An unbiased tissue transcriptome analysis identifies potential markers for skin phenotypes and therapeutic responses in atopic dermatitis
Ayano Fukushima‐Nomura, Hiroshi Kawasaki, Kiyoshi Yashiro et al. · Nature Communications
Open access |
2 Jun 2025 |
26 |
| 22 |
Evaluation of the Sysmex XT-2000iV haematology analyser for rat, dog and mouse whole blood samples
R. A. Mathers, G. O. Evans, John Bleby et al. · Comparative Clinical Pathology
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28 Apr 2008 |
24 |
| 23 |
Next-generation sequencing (NGS) profiling of matched tumor and circulating tumor DNA (ctDNA) in head and neck squamous cell carcinoma (HNSCC)
Panagiota Economopoulou, Aris Spathis, Ioannis Kotsantis et al. · Oral Oncology
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3 Mar 2023 |
23 |
| 24 |
Quantification of Amyloid-β in Plasma by Simple and Highly Sensitive Immunoaffinity Enrichment and LC-MS/MS Assay
Takuya Iino, Shunsuke Watanabe, Kazuto Yamashita et al. · The Journal of Applied Laboratory Medicine
Open access |
30 Nov 2020 |
23 |
| 25 |
Profiling of circulating tumor DNA in plasma of non‐small cell lung cancer patients, monitoring of epidermal growth factor receptor p.T790M mutated allelic fraction using beads, emulsion, amplification, and magnetics companion assay and evaluation in future application in mimicking circulating tumor cells
Jessica Garcia, Anne‐Sophie Wozny, Florence Geiguer et al. · Cancer Medicine
Open access |
21 May 2019 |
19 |
| 26 |
Detection and Quantification of KIT Mutations in ctDNA by Plasma Safe-SeqS
Johannes Fredebohm, Daniel H. Mehnert, Ann-Kathrin Löber et al. · Advances in experimental medicine and biology
Book chapter |
2016 |
19 |
| 27 |
Prospective study evaluating dynamic changes of cell-free HPV DNA in locoregional viral-associated oropharyngeal cancer treated with induction chemotherapy and response-adaptive treatment
Ari Joseph Rosenberg, Evgeny Izumchenko, Alexander T. Pearson et al. · BMC Cancer
Open access |
3 Jan 2022 |
18 |
| 28 |
Total and differential leucocyte counts in rat and mouse bronchoalveolar lavage fluids using the Sysmex XT-2000iV
R. A. Mathers, G. O. Evans, John Bleby et al. · Comparative Clinical Pathology
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20 Nov 2006 |
18 |
| 29 |
Correlates of Neutralizing/SARS-CoV-2-S1-binding Antibody Response with Adverse Effects and Immune Kinetics in BNT162b2-Vaccinated Individuals
Kenji Maeda et al. · Research Square
PreprintOpen access |
3 Sep 2021 |
16 |
| 30 |
Cyt‐Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2019 Conference Workshops
Kamila Czechowska et al. · Cytometry Part A
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Dec 2019 |
16 |
| 31 |
Fragmented red cells reference range for the Sysmex XN ®‐series of automated blood cell counters
Jean‐François Lesesve, Élodie Speyer, J.‐P. PEROL · International Journal of Laboratory Hematology
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17 Apr 2015 |
16 |
| 32 |
Stool-Based Testing for Post-Polypectomy Colorectal Cancer Surveillance Safely Reduces Colonoscopies: The MOCCAS Study
Beatriz G. Carvalho et al. · Gastroenterology
Open access |
30 Aug 2024 |
15 |
| 33 |
Clearance of ctDNA in triple-negative and HER2-positive breast cancer patients during neoadjuvant treatment is correlated with pathologic complete response
Nikaoly Ciriaco, Esther Zamora, Santiago Escrivá-de-Romaní et al. · Therapeutic Advances in Medical Oncology
Open access |
2022 |
15 |
| 34 |
Performance of the XN-2000 WPC channel-flagging to differentiate reactive and neoplastic leukocytosis
Peter Schuff‐Werner, Peter Kohlschein, Aliaksandra Maroz et al. · Clinical Chemistry and Laboratory Medicine (CCLM)
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24 Jan 2016 |
15 |
| 35 |
Performance evaluation of the new Sysmex XR-Series haematology analyser
Kenichi Fujimaki, Kornelia Hummel, Immaculate Magonde et al. · Practical Laboratory Medicine
Open access |
15 Feb 2024 |
14 |
| 36 |
A method comparison study of the high throughput automated HISCL® SARS‐CoV‐2 antigen assay using nasopharyngeal swab samples from symptomatic and asymptomatic subjects against conventional RT‐PCR
Joachim Linssen, Claire Schapendonk, Marion Münster et al. · Journal of Medical Virology
Open access |
25 Feb 2022 |
13 |
| 37 |
Th1 cytokine endotype discriminates and predicts severe complications in COVID-19
Takehiro Hasegawa, Takashi Hato, Toshitsugu Okayama et al. · European Cytokine Network
Open access |
Jun 2022 |
12 |
| 38 |
Evaluation of the Sysmex XN ‐31 automated analyser for blood donor malaria screening at Malawi Blood Transfusion Services
Bridon M’baya, Thom Mfune, Aubrey Samon et al. · Vox Sanguinis
Open access |
23 Sep 2021 |
12 |
| 39 |
Comparison of the cytokine adsorption ability in continuous renal replacement therapy using polyethyleneimine-coated polyacrylonitrile (AN69ST) or polymethylmethacrylate (PMMA) hemofilters: a pilot single-center open-label randomized control trial
Yoshihiko Nakamura, Hiroki Hatomoto, Shintaro Yamasaki et al. · European journal of medical research
Open access |
30 Jun 2023 |
11 |
| 40 |
The prognostic value of Krebs von den Lungen-6 and surfactant protein-A levels in the patients with interstitial lung disease
Peiyan Zheng, Xiaomao Zheng, Hasegawa Takehiro et al. · Journal of Translational Internal Medicine
Open access |
Sep 2021 |
11 |
| 41 |
Patient-centric thresholding of Cobas® EGFR mutation Test v2 for surveillance of EGFR-mutated metastatic non-small cell lung cancer
Jonas Claus, Dieter De Smet, Joke Breyne et al. · Scientific Reports
Open access |
6 Aug 2024 |
10 |
| 42 |
Analytical and clinical performance validation of HPV-SEQ, a novel NGS-based liquid biopsy platform for detection and quantification of human papilloma virus circulating tumor DNA
Samaneh Eickelschulte et al. · Oral Oncology
Open access |
26 Jun 2025 |
9 |
| 43 |
Broad spectrum of regorafenib activity on mutant KIT and absence of clonal selection in gastrointestinal stromal tumor (GIST): correlative analysis from the GRID trial
Michael Jeffers, Christian Kappeler, Iris Kuss et al. · Gastric Cancer
Open access |
20 Jan 2022 |
9 |
| 44 |
Routine Molecular Screening of Patients with Advanced Non-SmallCell Lung Cancer in Circulating Cell-Free DNA at Diagnosis and During Progression Using OncoBEAMTM EGFR V2 and NGS Technologies
Jessica Garcia, Arnaud Gauthier, Gaëlle Lescuyer et al. · Molecular Diagnosis & Therapy
Open access |
Mar 2021 |
9 |
| 45 |
Surveillance of Disease Progression in Metastatic Breast Cancer by Molecular Counting of Circulating Tumor DNA Using Plasma-SeqSensei Breast Cancer in Vitro Diagnostics Assay
Geert Antoine Martens, Jan H. Demol, Franceska Dedeurwaerdere et al. · Journal of Molecular Diagnostics
Open access |
7 Nov 2024 |
8 |
| 46 |
ExoCounter Assays Identify Women Who May Develop Early-Onset Preeclampsia From 12.5 μL First-Trimester Serum by Characterizing Placental Small Extracellular Vesicles
Shuhan Jiang, Wei Zhang, Qing Cao et al. · Hypertension
Open access |
25 May 2023 |
8 |
| 47 |
Bone Marrow Cells and Myocardial Regeneration
Fu‐Sheng Wang, Cathy Trester · International Journal of Hematology
|
May 2004 |
8 |
| 48 |
Development of a new HISCL automated CXCL9 immunoassay
Takehiro Hasegawa, Maho Yoshida, Shunsuke Watanabe et al. · Scientific Reports
Open access |
Apr 2023 |
7 |
| 49 |
Blood-based RAS mutation testing: concordance with tissue-based RAS testing and mutational changes on progression
Theodora Germetaki, Camille Nicholls, Richard Adams et al. · Future Oncology
Open access |
27 Jul 2020 |
7 |
| 50 |
Measurement of CD4+ T cells in point‐of‐care settings with the Sysmex pocH‐100i haematological analyser
Carol J. Briggs, SJ Machin, M. K. Müller et al. · International Journal of Laboratory Hematology
Open access |
23 Feb 2009 |
7 |