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Institution · Tanabe Research Laboratories

Most cited papers from Tanabe Research Laboratories

Tanabe Research Laboratories

What are the most cited papers from Tanabe Research Laboratories?

The most cited paper from Tanabe Research Laboratories is "IκB Kinases Phosphorylate NF-κB p65 Subunit on Serine 536 in the Transactivation Domain" (Hiroaki Sakurai, Hiroaki Chiba, Hidetaka Miyoshi et al., 1999), with 825 citations. Next come "Overview of PDEs and Their Regulation" (808) and "Skeletal Muscle FOXO1 (FKHR) Transgenic Mice Have Less Skeletal Muscle Mass, Down-regulated Type I (Slow Twitch/Red Muscle) Fiber Genes, and Impaired Glycemic Control" (573).

Showing 50 of 61 papers. Every paper with more than 80 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 IκB Kinases Phosphorylate NF-κB p65 Subunit on Serine 536 in the Transactivation Domain Hiroaki Sakurai, Hiroaki Chiba, Hidetaka Miyoshi et al. · Journal of Biological Chemistry Open access Oct 1999 825
2 Overview of PDEs and Their Regulation Kenji Omori, Jun Kotera · Circulation Research 16 Feb 2007 808
3 Skeletal Muscle FOXO1 (FKHR) Transgenic Mice Have Less Skeletal Muscle Mass, Down-regulated Type I (Slow Twitch/Red Muscle) Fiber Genes, and Impaired Glycemic Control Yasutomi Kamei, Shinji Miura, Miki T. SUZUKI et al. · Journal of Biological Chemistry Open access 24 Jul 2004 573
4 Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response Taiichi Katayama, Kazunori Imaizumi, Naoya Sato et al. · Nature Cell Biology 29 Oct 1999 529
5 Cloning and Characterization of a Novel Human Phosphodiesterase That Hydrolyzes Both cAMP and cGMP (PDE10A) Kotomi Fujishige, Jun Kotera, Hideo Michibata et al. · Journal of Biological Chemistry Open access Jun 1999 408
6 Greater Oxidative Stress in Healthy Young Men Compared With Premenopausal Women Tomomi Ide, Hiroyuki Tsutsui, Noriko Ohashi et al. · Arteriosclerosis Thrombosis and Vascular Biology Open access Mar 2002 362
7 Elevated Cyclic AMP Inhibits NF-κB-mediated Transcription in Human Monocytic Cells and Endothelial Cells Véronique Ollivier, Graham C. Parry, Ronald R. Cobb et al. · Journal of Biological Chemistry Open access Aug 1996 338
8 Role of host angiotensin II type 1 receptor in tumor angiogenesis and growth Kimiyasu Egami, Toyoaki Murohara, Toshifumi Shimada et al. · Journal of Clinical Investigation Open access Jul 2003 336
9 Cytokine induction of monocyte chemoattractant protein‐1 gene expression in human endothelial cells depends on the cooperative action of NF‐χB and AP‐1 Teresa Martin, Pina M. Cardarelli, Graham C. Parry et al. · European Journal of Immunology May 1997 319
10 Optical properties of cyclic olefin copolymers G. Khanarian · Optical Engineering Jun 2001 298
11 Mammalian Prenylcysteine Carboxyl Methyltransferase Is in the Endoplasmic Reticulum Qun Dai, Edwin Choy, Vi Kien Chiu et al. · Journal of Biological Chemistry Open access Jun 1998 295
12 Expression and regulation of chemokine receptors in human natural killer cells Marit Inngjerdingen, Bassam B. Damaj, Azzam A. Maghazachi · Blood 15 Jan 2001 293
13 Receptor Activator of NF-κB Ligand (RANKL) Activates TAK1 Mitogen-Activated Protein Kinase Kinase Kinase through a Signaling Complex Containing RANK, TAB2, and TRAF6 Junko Mizukami, Giichi Takaesu, Hiroyuki Akatsuka et al. · Molecular and Cellular Biology Open access Feb 2002 282
14 TMC-95A, B, C, and D, Novel Proteasome Inhibitors Produced by Apiospora montagnei Sacc. TC 1093. Taxonomy, Production, Isolation, and Biological Activities. Yutaka Koguchi, Jun Kohno, MAKI NISHIO et al. · The Journal of Antibiotics Open access 2000 276
15 l ‐Type amino acid transporter 1 inhibitors inhibit tumor cell growth Koji Oda, Noriko Hosoda, Hiroshi Endô et al. · Cancer Science Open access 8 Oct 2009 274
16 Pressure Overload Induces Cardiac Hypertrophy in Angiotensin II Type 1A Receptor Knockout Mice Koichiro Harada, Issei Komuro, Ichiro Shiojima et al. · Circulation Open access 19 May 1998 258
17 T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes. Akira Oku, Kiichiro Ueta, Kenji Arakawa et al. · Diabetes Sep 1999 256
18 The signaling networks of the herpesvirus entry mediator (TNFRSF14) in immune regulation Marcos W. Steinberg, Timothy C. Cheung, Carl F. Ware · Immunological Reviews ReviewOpen access 21 Oct 2011 251
19 Angiotensin II Type 1A Receptor Knockout Mice Display Less Left Ventricular Remodeling and Improved Survival After Myocardial Infarction Koichiro Harada, Takeshi Sugaya, Kazuo Murakami et al. · Circulation 16 Nov 1999 204
20 Striatum‐ and testis‐specific phosphodiesterase PDE10A Kotomi Fujishige, Jun Kotera, Kenji Omori · European Journal of Biochemistry Open access 15 Dec 1999 185
21 Development of synthetic lung surfactants. Yuji Tanaka, Takahito Takei, T Aiba et al. · Journal of Lipid Research Open access Jul 1988 184
22 Two cis-acting elements in the 3′ untranslated region of α-CaMKII regulate its dendritic targeting Yasutake Mori, Kazunori Imaizumi, Taiichi Katayama et al. · Nature Neuroscience Nov 2000 181
23 Effect of Diltiazem on Electrical and Mechanical Activity of Isolated Cardiac Ventricular Muscle of Guinea Pig Hiromichi Nakajima, Masao Hoshiyama, Keiko Yamashita et al. · The Japanese Journal of Pharmacology Open access 1975 177
24 Separation and determination of lipophilic corticosteroids and benzothiazepin analogues by micellar electrokinetic chromatography using bile salts Hiroyuki Nishi, Tsukasa Fukuyama, Masaaki Matsuo et al. · Journal of Chromatography A 1990 168
25 Importance of Monocyte Chemoattractant Protein-1 Pathway in Neointimal Hyperplasia After Periarterial Injury in Mice and Monkeys Kensuke Egashira, Qingwei David Zhao, Chu Kataoka et al. · Circulation Research 14 Jun 2002 166
26 Chiral separation of diltiazem, trimetoquinol and related compounds by micellar electrokinetic chromatography with bile salts Hiroyuki Nishi, Tsukasa Fukuyama, Masaaki Matsuo et al. · Journal of Chromatography A Aug 1990 160
27 Molecular Cloning of a Novel Polypeptide, DP5, Induced during Programmed Neuronal Death Kazunori Imaizumi, Manabu Tsuda, Yuji Imai et al. · Journal of Biological Chemistry Open access Jul 1997 160
28 Protein encapsulation into biodegradable microspheres by a novel S/O/W emulsion method using poly(ethylene glycol) as a protein micronization adjuvant Takahiro Morita, Yumi Sakamura, Yuji Horikiri et al. · Journal of Controlled Release Dec 2000 156
29 Angiotensin II plays a pathogenic role in immune-mediated renal injury in mice Yutaka Hisada, Takeshi Sugaya, Masaya Yamanouchi et al. · Journal of Clinical Investigation Open access Mar 1999 153
30 Human NK Cells Express CC Chemokine Receptors 4 and 8 and Respond to Thymus and Activation-Regulated Chemokine, Macrophage-Derived Chemokine, and I-309 Marit Inngjerdingen, Bassam B. Damaj, Azzam A. Maghazachi · The Journal of Immunology Open access Apr 2000 151
31 Expression of Zinc Transporter Gene, ZnT-1, Is Induced after Transient Forebrain Ischemia in the Gerbil Manabu Tsuda, Kazunori Imaizumi, Taiichi Katayama et al. · Journal of Neuroscience Open access Sep 1997 142
32 Separation of water-soluble vitamins by micellar electrokinetic chromatography Hiroyuki Nishi, Nobuchika Tsumagari, Toshio Kakimoto et al. · Journal of Chromatography A 1989 131
33 Role of Angiotensin II–Regulated Apoptosis Through Distinct AT 1 and AT 2 Receptors in Neointimal Formation Jun Suzuki, Masaru Iwai, Hironori Nakagami et al. · Circulation 13 Aug 2002 130
34 Ca2+ channel antagonists and neuroprotection from cerebral ischemia Tsutomu Kobayashi, Yasuo Mori · European Journal of Pharmacology Dec 1998 126
35 Preparation of enteric coated timed-release press-coated tablets and evaluation of their function by in vitro and in vivo tests for colon targeting Eiji Fukui, Nobuteru Miyamura, Katsuji Uemura et al. · International Journal of Pharmaceutics Jun 2000 120
36 Separation of β-lactam antibiotics by micellar electrokinetic chromatography Hiroyuki Nishi, Nobuchika Tsumagari, Toshio Kakimoto et al. · Journal of Chromatography A 1989 120
37 Purification and Properties of β-Galactosidase from Aspergillus oryzae Yuji Tanaka, Akihiro KAGAMIISHI, Akira Kiuchi et al. · The Journal of Biochemistry 1975 119
38 Evidence for the importance of angiotensin II type 1 receptor in ischemia-induced angiogenesis Ken‐ichiro Sasaki, Toyoaki Murohara, Hisao Ikeda et al. · Journal of Clinical Investigation Open access Mar 2002 112
39 Usefulness and Limitation of DiBAC4(3), a Voltage-Sensitive Fluorescent Dye, for the Measurement of Membrane Potentials Regulated by Recombinant Large Conductance Ca2+-Activated K+ Channels in HEK293 Cells Aki Yamada, Norikazu Gaja, Susumu Ohya et al. · The Japanese Journal of Pharmacology Open access 2001 111
40 Studies on a New 1, 5-Benzothiazepine Derivative (CRD-401). IV. Coronary Vasodilating Effect and Structure-Activity Relationship Taku Nagao, Masanori Sato, Hiromichi Nakajima et al. · Chemical and Pharmaceutical Bulletin Open access 1973 101
41 A Two-Week, Randomized, Double-masked Study to Evaluate Safety and Efficacy of Lubricin (150 μg/mL) Eye Drops Versus Sodium Hyaluronate (HA) 0.18% Eye Drops (Vismed®) in Patients with Moderate Dry Eye Disease Alessandro Lambìase, Benjamin David Sullivan, Tannin A. Schmidt et al. · The Ocular Surface 9 Sep 2016 99
42 Biocatalysis: Immobilized cells and enzymes Ichiro Chibata, Tetsuya Tosa, Tadashi Sato · Journal of Molecular Catalysis Sep 1986 99
43 Anti-C5a receptor antibodies. Characterization of neutralizing antibodies specific for a peptide, C5aR-(9-29), derived from the predicted amino-terminal sequence of the human C5a receptor. Eric Lease Morgan, Julia A. Ember, Sam D. Sanderson et al. · The Journal of Immunology Jul 1993 98
44 Pharmaceutical applications of micelles in chromatography and electrophoresis Hiroyuki Nishi · Journal of Chromatography A Sep 1997 95
45 Suppression of arthritis by the inhibitors of dipeptidyl peptidase IV Sumiko Tanaka, Takanori Murakami, Hiroshi Horikawa et al. · International Journal of Immunopharmacology 1997 94
46 Drug release characteristics of multi-reservoir type microspheres with poly(dl-lactide-co-glycolide) and poly(dl-lactide) Akihiro Matsumoto, Yasuhisa Matsukawa, Takehiko Suzuki et al. · Journal of Controlled Release 3 Jun 2005 92
47 The Antidiabetic Agent Thiazolidinedione Stimulates the Interaction between PPARγ and CBP Junko Mizukami, Tomoyasu Taniguchi · Biochemical and Biophysical Research Communications Nov 1997 92
48 An Organic Acid-Induced Sigmoidal Release System for Oral Controlled-Release Preparations. 2. Permeability Enhancement of Eudragit RS Coating Led by the Physicochemical Interactions with Organic Acid Shinji Narisawa, Minako Nagata, Yoshiyuki HIRAKAWA et al. · Journal of Pharmaceutical Sciences Feb 1996 91
49 STUDIES ON TETRAHYDROISOQUINOLINES (THI) (I) BRONCHODILATOR ACTIVITY AND STRUCTURE-ACTIVITY RELATIONSHIP Yoshio Iwasawa, Akio Kiyomoto · The Japanese Journal of Pharmacology Open access 1967 88
50 Anti-apoptotic Effect of Acetyl-l-carnitine and l-Carnitine in Primary Cultured Neurons. Taketoshi Ishii, Yasuko Shimpo, Yuzo Matsuoka et al. · The Japanese Journal of Pharmacology Open access 2000 87

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.