Most cited papers from Target (United States)
What are the most cited papers from Target (United States)?
The most cited paper from Target (United States) is "Pembrolizumab versus Ipilimumab in Advanced Melanoma" (Caroline Robert et al., 2015), with 5,968 citations. Next come "Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer" (2,702) and "The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids" (2,411).
Showing 50 of 60 papers. Every paper with more than 399 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Pembrolizumab versus Ipilimumab in Advanced Melanoma Caroline Robert et al. · New England Journal of Medicine | 19 Apr 2015 | 5,968 |
| 2 | Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer Shanu Modi et al. · New England Journal of Medicine | 5 Jun 2022 | 2,702 |
| 3 | The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids Andrew J. Brown et al. · Journal of Biological Chemistry | Mar 2003 | 2,411 |
| 4 | Melanoma staging: Evidence‐based changes in the American Joint Committee on Cancer eighth edition cancer staging manual Jeffrey E. Gershenwald, Richard A. Scolyer, Kenneth R. Hess et al. · CA A Cancer Journal for Clinicians | 13 Oct 2017 | 2,317 |
| 5 | Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis James W. Bainbridge, Alexander J. Smith, Susie S. Barker et al. · New England Journal of Medicine | 27 Apr 2008 | 1,933 |
| 6 | Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand Jian-Ping Xiong, Thilo Stehle, Rongguang Zhang et al. · Science | 5 Apr 2002 | 1,616 |
| 7 | Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results Gooitzen M. van Dam, George Themelis, Lucia M. A. Crane et al. · Nature Medicine | 18 Sep 2011 | 1,544 |
| 8 | 5th ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 5) Fátima Cardoso et al. · Annals of Oncology | 23 Sep 2020 | 1,397 |
| 9 | Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions Aaron D. Goldberg et al. · Cell | Mar 2010 | 1,314 |
| 10 | The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis Marloes J.M. Gooden, Geertruida H. de Bock, Ninke Leffers et al. · British Journal of Cancer | 31 May 2011 | 1,305 |
| 11 | Osteocyte control of bone formation via sclerostin, a novel BMP antagonist D. G. Winkler, May Kung Sutherland, James C. Geoghegan et al. · The EMBO Journal | 21 Nov 2003 | 1,119 |
| 12 | Major types and time–space distribution of Mesozoic ore deposits in South China and their geodynamic settings Mao Jingwen, Yanbo Cheng, Chen Maohong et al. · Mineralium Deposita | 29 Oct 2012 | 1,059 |
| 13 | A catalog of genetic loci associated with kidney function from analyses of a million individuals Lifelines Cohort Study et al. · Nature Genetics | 31 May 2019 | 946 |
| 14 | Surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system Gert Storm, Sheila O. Belliot, Toos Daemen et al. · Advanced Drug Delivery Reviews | Oct 1995 | 876 |
| 15 | The growth of the continental crust: Constraints from zircon Hf-isotope data Elena A. Belousova, Yu. A. Kostitsyn, William L. Griffin et al. · Lithos | 4 Aug 2010 | 870 |
| 16 | Substantial Susceptibility of Chronic Lymphocytic Leukemia to BCL2 Inhibition: Results of a Phase I Study of Navitoclax in Patients With Relapsed or Refractory Disease Andrew Warwick Roberts, John Francis Seymour, Jennifer R. Brown et al. · Journal of Clinical Oncology | 20 Dec 2011 | 831 |
| 17 | Sentinel Node Dissection Is Safe in the Treatment of Early-Stage Vulvar Cancer Ate G.J. van der Zee, Maaike H.M. Oonk, Joanne A. de Hullu et al. · Journal of Clinical Oncology | 16 Feb 2008 | 821 |
| 18 | Remote sensing of solar-induced chlorophyll fluorescence (SIF) in vegetation: 50 years of progress Gina H. Mohammed et al. · Remote Sensing of Environment | 13 Jul 2019 | 775 |
| 19 | Stereospecific PARP Trapping by BMN 673 and Comparison with Olaparib and Rucaparib Junko Murai, Shar-Yin Naomi Huang, Amèlie Renaud et al. · Molecular Cancer Therapeutics | 19 Dec 2013 | 775 |
| 20 | Attenuated Cold Sensitivity in TRPM8 Null Mice Raymond W. Colburn, Mary Lou Lubin, Dennis J. Stone et al. · Neuron | May 2007 | 775 |
| 21 | Stability and kinetics of G-quadruplex structures Andrew N. Lane, Jonathan Brad Chaires, Robert D. Gray et al. · Nucleic Acids Research | 21 Aug 2008 | 748 |
| 22 | Strategies towards statistically robust interpretations of in situ U–Pb zircon geochronology Christopher J. Spencer, Christopher L. Kirkland, Richard Taylor · Geoscience Frontiers | 15 Dec 2015 | 734 |
| 23 | The Composition and Evolution of Lithospheric Mantle: a Re-evaluation and its Tectonic Implications William L. Griffin, Suzanne Yvette O'Reilly, Juan Carlos Afonso et al. · Journal of Petrology | 4 Jul 2008 | 715 |
| 24 | British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma Matthew R Banks, David Yates Graham, Marnix Jansen et al. · Gut | 5 Jul 2019 | 657 |
| 25 | Mitochondrial metabolism promotes adaptation to proteotoxic stress Peter Tsvetkov, Alexandre Detappe, Kai Cai et al. · Nature Chemical Biology | 27 May 2019 | 653 |
| 26 | The influence of lead discovery strategies on the properties of drug candidates György Miklós Keserű, Gergely M. Makara · Nature Reviews Drug Discovery | 27 Feb 2009 | 633 |
| 27 | New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries Nick R. G. Shrine et al. · Nature Genetics | 25 Feb 2019 | 615 |
| 28 | Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A 1 –A 2A Receptor Heteromers Francisco Ciruela, Vicent Casadó, Ricardo J. Rodrigues et al. · Journal of Neuroscience | 15 Feb 2006 | 592 |
| 29 | T–cell mediated rejection of gene–modified HIV–specific cytotoxic T lymphocytes in HIV–infected patients Stanley R. Riddell, Mark Elliott, Deborah A. Lewinsohn et al. · Nature Medicine | Feb 1996 | 579 |
| 30 | Sediment-Hosted Lead-Zinc Deposits in Earth History David L. Leach, Dwight C. Bradley, David L. Huston et al. · Economic Geology | May 2010 | 570 |
| 31 | Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data Ioanna Tachmazidou et al. · Nature Genetics | 21 Jan 2019 | 551 |
| 32 | A Large Non-immunized Human Fab Fragment Phage Library That Permits Rapid Isolation and Kinetic Analysis of High Affinity Antibodies Hans J. de Haard, Nicole van Neer, Anneke W. Reurs et al. · Journal of Biological Chemistry | Jun 1999 | 534 |
| 33 | A genetic linkage between subduction- and collision-related porphyry Cu deposits in continental collision zones Zengqian Hou, Zhiming Yang, Yongjun Lu et al. · Geology | 6 Feb 2015 | 526 |
| 34 | Loss of 53BP1 Causes PARP Inhibitor Resistance in Brca1 -Mutated Mouse Mammary Tumors Janneke E. Jaspers, Ariena J. Kersbergen, Ute Boon et al. · Cancer Discovery | 26 Oct 2012 | 523 |
| 35 | MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease Pierre‐Antoine Juge et al. · New England Journal of Medicine | 20 Oct 2018 | 518 |
| 36 | Antibody phage display technology and its applications Hennie R. Hoogenboom, Adriaan P. de Bruı̈ne, Simon E. Hufton et al. · Immunotechnology | Jun 1998 | 515 |
| 37 | Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer Mary Anna Venneri, Michele De Palma, Maurilio Ponzoni et al. · Blood | 27 Feb 2007 | 505 |
| 38 | Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury Jinghai James Xu, Peter V. Henstock, Margaret C. Dunn et al. · Toxicological Sciences | 3 Jun 2008 | 495 |
| 39 | Lung microbiome dynamics in COPD exacerbations Zhang Wang, Mona Bafadhel, Koirobi Haldar et al. · European Respiratory Journal | 25 Feb 2016 | 491 |
| 40 | Human organoids in basic research and clinical applications Xiao-Yan Tang, Shanshan Wu, Da Wang et al. · Signal Transduction and Targeted Therapy | 24 May 2022 | 487 |
| 41 | In vivo gene transfer via intravenous administration of cationic lipid–protamine–DNA (LPD) complexes S Li, Leaf Huang · Gene Therapy | Sep 1997 | 476 |
| 42 | Protamine sulfate enhances lipid-mediated gene transfer FL Sorgi, Sukanta S. Bhattacharya, Leaf Huang · Gene Therapy | Sep 1997 | 457 |
| 43 | Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells Hua Zhu, Hao Wu, Xiuping Liu et al. · Autophagy | 16 Aug 2009 | 453 |
| 44 | Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire Jacob Glanville, Wenwu Zhai, Jan Berka et al. · Proceedings of the National Academy of Sciences | 29 Oct 2009 | 451 |
| 45 | Isolation and Characterization of Griffithsin, a Novel HIV-inactivating Protein, from the Red Alga Griffithsia sp. Toshiyuki Mori, Barry R. O’Keefe, Raymond C. Sowder et al. · Journal of Biological Chemistry | 22 Dec 2004 | 450 |
| 46 | Inhibitors of Ubiquitin-Activating Enzyme (E1), a New Class of Potential Cancer Therapeutics Yili Yang, Jirouta Kitagaki, Ren‐Ming Dai et al. · Cancer Research | Oct 2007 | 450 |
| 47 | The RASSF1A tumor suppressor Howard Donninger, Michele D. Vos, Geoffrey Clark · Journal of Cell Science | 15 Sep 2007 | 446 |
| 48 | Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels German Chronic Kidney Disease Study et al. · Nature Genetics | Oct 2019 | 442 |
| 49 | Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity Valérie Turcot et al. · Nature Genetics | 19 Dec 2017 | 438 |
| 50 | Designing meaningful density functional theory calculations in materials science—a primer Ann E. Mattsson, Peter A. Schultz, M. P. Desjarlais et al. · Modelling and Simulation in Materials Science and Engineering | 19 Nov 2004 | 437 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.