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Most cited papers from Texas Biomedical Research Institute

What are the most cited papers from Texas Biomedical Research Institute?

The most cited paper from Texas Biomedical Research Institute is "The mutational constraint spectrum quantified from variation in 141,456 humans" (Konrad J. Karczewski et al., 2020), with 10,422 citations. Next come "Genetic studies of body mass index yield new insights for obesity biology" (4,954) and "Multipoint Quantitative-Trait Linkage Analysis in General Pedigrees" (3,078).

Showing 50 of 60 papers. Every paper with more than 515 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The mutational constraint spectrum quantified from variation in 141,456 humans Konrad J. Karczewski et al. · Nature Open access177 authors 27 May 2020 10,422
2 Genetic studies of body mass index yield new insights for obesity biology The LifeLines Cohort Study et al. · Nature Open access487 authors 10 Feb 2015 4,954
3 Multipoint Quantitative-Trait Linkage Analysis in General Pedigrees Laura A. Almasy, John Blangero · The American Journal of Human Genetics Open access May 1998 3,078
4 Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. James E. Hixson, D.T. Vernier · Journal of Lipid Research Open access Mar 1990 2,963
5 Production of infectious hepatitis C virus in tissue culture from a cloned viral genome Takaji Wakita, Thomas Pietschmann, Takanobu Kato et al. · Nature Medicine Open access 12 Jun 2005 2,753
6 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors 2 Jan 2021 2,743
7 Defining the role of common variation in the genomic and biological architecture of adult human height Andrew R. Wood et al. · Nature Genetics 446 authors 5 Oct 2014 2,114
8 Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes Feng Gao, Elizabeth Bailes, David L. Robertson et al. · Nature 4 Feb 1999 1,753
9 New genetic loci link adipose and insulin biology to body fat distribution Dmitry Shungin et al. · Nature Open access410 authors 10 Feb 2015 1,726
10 Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection Robert E. Lanford, Elisabeth S. Hildebrandt-Eriksen, Andreas Petri et al. · Science Open access 3 Dec 2009 1,664
11 Evolutionary and Biomedical Insights from the Rhesus Macaque Genome Richard A. Gibbs et al. · Science Open access176 authors 12 Apr 2007 1,452
12 Neuroactive steroids Steven M. Paul, Robert H. Purdy · The FASEB Journal Mar 1992 1,329
13 Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies Anderson M. Winkler, Peter V Kochunov, John Blangero et al. · NeuroImage Open access 17 Dec 2009 1,234
14 A structural variation reference for medical and population genetics Ryan L. Collins et al. · Nature Open access208 authors 27 May 2020 1,205
15 The genetic architecture of type 2 diabetes Christian Fuchsberger et al. · Nature Open access301 authors 11 Jul 2016 1,129
16 Cellular Senescence in Aging Primates Utz Herbig, Mark Ferreira, Laura Condel et al. · Science 2 Feb 2006 1,101
17 Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain. Robert H. Purdy, A. Leslie Morrow, Perry H. Moore et al. · Proceedings of the National Academy of Sciences Open access 15 May 1991 964
18 Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study Aung Pyae Phyo, Standwell C. Nkhoma, Kasia Stepniewska et al. · The Lancet Open access 5 Apr 2012 942
19 Common genetic variants influence human subcortical brain structures The Alzheimer’s Disease Neuroimaging Initiative et al. · Nature Open access291 authors 20 Jan 2015 934
20 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance Alisa K Manning et al. · Nature Genetics Open access216 authors 13 May 2012 894
21 The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data Paul M. Thompson et al. · Brain Imaging and Behavior Open access289 authors 7 Jan 2014 891
22 Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing Laura Riva et al. · Nature Open access 24 Jul 2020 861
23 Microsatellite Markers Reveal a Spectrum of Population Structures in the Malaria Parasite Plasmodium falciparum Timothy J. C. Anderson, Bernhard Haubold, Jeff T. Williams et al. · Molecular Biology and Evolution Open access Oct 2000 836
24 HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help Arash Grakoui, Naglaa H. Shoukry, David J. Woollard et al. · Science 23 Oct 2003 828
25 An abundance of X-linked genes expressed in spermatogonia P. Jeremy Wang, John Robert McCarrey, Fengtang Yang et al. · Nature Genetics Apr 2001 801
26 The transcriptional landscape of age in human peripheral blood Marjolein J. Peters et al. · Nature Communications Open access137 authors 22 Oct 2015 783
27 BNT162b vaccines protect rhesus macaques from SARS-CoV-2 Annette B. Vogel et al. · Nature Open access Feb 2021 761
28 Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line. Tal Kafri, M. Silber Ariel, Michael Brandeis et al. · Genes & Development Open access May 1992 739
29 Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences Tarjei S. Mikkelsen et al. · Nature Open access May 2007 728
30 A pathogenic picornavirus acquires an envelope by hijacking cellular membranes Zongdi Feng, Lucinda Hensley, Kevin L. McKnight et al. · Nature Open access 28 Mar 2013 728
31 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study Thomas W. Winkler et al. · PLoS Genetics Open access439 authors Oct 2015 699
32 Obesity Accelerates the Progression of Coronary Atherosclerosis in Young Men Henry C. McGill, Clyde Alex McMahan, Edward E. Herderick et al. · Circulation Open access 11 Jun 2002 692
33 Integrated omics: tools, advances and future approaches Biswapriya B. Misra, Carl D. Langefeld, Michael Olivier et al. · Journal of Molecular Endocrinology 13 Jul 2018 686
34 Natural history of Williams syndrome: Physical characteristics Colleen A. Morris, Susan A. Demsey, Claire O. Leonard et al. · The Journal of Pediatrics Aug 1988 678
35 Comprehensive statistical study of 452 BRCA1 missense substitutions with classification of eight recurrent substitutions as neutral Sean V. Tavtigian, A M Deffenbaugh, L Yin et al. · Journal of Medical Genetics Open access 13 Jul 2005 677
36 Origin of atherosclerosis in childhood and adolescence Henry C. McGill, C. Alex McMahan, Edward E. Herderick et al. · American Journal of Clinical Nutrition Open access Nov 2000 667
37 Identification of common variants associated with human hippocampal and intracranial volumes the Alzheimer's Disease Neuroimaging Initiative (ADNI) et al. · Nature Genetics Open access204 authors 15 Apr 2012 662
38 Variations in GABRA2, Encoding the α2 Subunit of the GABAA Receptor, Are Associated with Alcohol Dependence and with Brain Oscillations Howard J. Edenberg, Danielle M. Dick, Xiaoling Xuei et al. · The American Journal of Human Genetics Open access 17 Mar 2004 660
39 Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome Ahmed H. Kissebah, Gabriele E. Sonnenberg, Joel B. Myklebust et al. · Proceedings of the National Academy of Sciences Open access 19 Dec 2000 643
40 Why primate models matter Kimberley A. Phillips, Karen Lisa Bales, John P. Capitanio et al. · American Journal of Primatology Open access 10 Apr 2014 632
41 Protease inhibitors targeting coronavirus and filovirus entry Yanchen Zhou, Punitha Vedantham, Kai Lü et al. · Antiviral Research Open access 7 Feb 2015 626
42 ECG T-Wave Patterns in Genetically Distinct Forms of the Hereditary Long QT Syndrome Arthur J. Moss, Wojciech Zaręba, Jesaia Benhorin et al. · Circulation 15 Nov 1995 625
43 Dengue Virus Structural Differences That Correlate with Pathogenesis Katrin Claire Leitmeyer, David W. Vaughn, Douglas M. Watts et al. · Journal of Virology Open access Jun 1999 620
44 Polymorphisms in the Tyrosine Kinase 2 and Interferon Regulatory Factor 5 Genes Are Associated with Systemic Lupus Erythematosus Snævar Sigurðsson, Gunnel Nordmark, Harald H.H. Göring et al. · The American Journal of Human Genetics Open access 8 Feb 2005 613
45 DNA polymerase ? inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes Thomas W. Glover, Carol S. Berger, Jane Coyle et al. · Human Genetics Jul 1984 609
46 Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160 Phillip W. Berman, Timothy J. Gregory, Lavon M. Riddle et al. · Nature Open access 14 Jun 1990 592
47 REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters Alina Baum et al. · Science Open access 9 Oct 2020 586
48 Phylogeny and Divergence-Date Estimates of Rapid Radiations in Muroid Rodents Based on Multiple Nuclear Genes Scott J. Steppan, Ronald M. Adkins, Joel Anderson · Systematic Biology Aug 2004 574
49 Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment Yasuteru Sakurai, Andrey A. Kolokoltsov, Cheng‐Chang Chen et al. · Science Open access 27 Feb 2015 569
50 Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations M. Geoffrey Hayes et al. · Nature Communications Open access 18 Aug 2015 555

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.