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Most cited papers from The Coordinating Center

What are the most cited papers from The Coordinating Center?

The most cited paper from The Coordinating Center is "Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin" (Diabetes Prevention Program Research Group, 2002), with 19,192 citations. Next come "A simulation study of the number of events per variable in logistic regression analysis" (9,562) and "Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study" (3,665).

Showing 50 of 60 papers. Every paper with more than 434 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin Diabetes Prevention Program Research Group · New England Journal of Medicine Open access 7 Feb 2002 19,192
2 A simulation study of the number of events per variable in logistic regression analysis Peter N. Peduzzi, John Concato, Elizabeth Kemper et al. · Journal of Clinical Epidemiology Open access Dec 1996 9,562
3 Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study Karen L. Kotloff et al. · The Lancet 13 May 2013 3,665
4 Gemfibrozil for the Secondary Prevention of Coronary Heart Disease in Men with Low Levels of High-Density Lipoprotein Cholesterol Hanna E. Bloomfield, Sander J. Robins, Dorothea Collins et al. · New England Journal of Medicine Open access 5 Aug 1999 3,470
5 Preliminary Report: Effect of Encainide and Flecainide on Mortality in a Randomized Trial of Arrhythmia Suppression after Myocardial Infarction The Cardiac Arrhythmia Suppression Trial (CAST) Investigators · New England Journal of Medicine 10 Aug 1989 3,320
6 Mortality and Morbidity in Patients Receiving Encainide, Flecainide, or Placebo Debra S. Echt, Philip R. Liebson, L. Brent Mitchell et al. · New England Journal of Medicine Open access 21 Mar 1991 3,280
7 Once-Yearly Zoledronic Acid for Treatment of Postmenopausal Osteoporosis Dennis M. Black et al. · New England Journal of Medicine Open access 3 May 2007 2,988
8 Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge. James H. Chesebro, Genell L. Knatterud, Robert Roberts et al. · Circulation Open access Jul 1987 2,257
9 Importance of events per independent variable in proportional hazards regression analysis II. Accuracy and precision of regression estimates Peter N. Peduzzi, John Concato, Alvan R. Feinstein et al. · Journal of Clinical Epidemiology Open access Dec 1995 2,186
10 Hundreds of variants clustered in genomic loci and biological pathways affect human height Hana Lango Allen et al. · Nature Open access293 authors 29 Sep 2010 2,063
11 Efficacy of Carotid Endarterectomy for Asymptomatic Carotid Stenosis Robert W. Hobson, David G. Weiss, William S. Fields et al. · New England Journal of Medicine Open access 28 Jan 1993 1,443
12 Effect of Weight Loss With Lifestyle Intervention on Risk of Diabetes Richard F. Hamman, Rena R. Wing, Sharon L. Edelstein et al. · Diabetes Care Open access 25 Aug 2006 1,363
13 A Comparison of Four Treatments for Generalized Convulsive Status Epilepticus David M. Treiman, Patti D. Meyers, Nancy Y. Walton et al. · New England Journal of Medicine Open access 17 Sep 1998 1,341
14 Glucosamine, Chondroitin Sulfate, and the Two in Combination for Painful Knee Osteoarthritis Daniel O. Clegg et al. · New England Journal of Medicine Open access 22 Feb 2006 1,340
15 Coronary-Artery Revascularization before Elective Major Vascular Surgery Edward O. McFalls, Herbert B. Ward, THOMAS E. MORITZ et al. · New England Journal of Medicine Open access 30 Dec 2004 1,315
16 Diabetes Mellitus after Kidney Transplantation in the United States Bertram L. Kasiske, Jon J. Snyder, David T. Gilbertson et al. · American Journal of Transplantation Open access Feb 2003 1,298
17 Cystatin C and the Risk of Death and Cardiovascular Events among Elderly Persons Michael G. Shlipak, Mark J. Sarnak, Ronit Katz et al. · New England Journal of Medicine Open access 18 May 2005 1,257
18 The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women John A. Kanis et al. · Osteoporosis International 23 Feb 2007 1,228
19 SERUM CHOLESTEROL, BLOOD PRESSURE, AND MORTALITY: IMPLICATIONS FROM A COHORT OF 361 662 MEN MichaelJ Martin, WarrenS Browner, S. B. Hulley et al. · The Lancet Oct 1986 1,131
20 Relation of C-Reactive Protein and Coronary Heart Disease in the MRFIT Nested Case-Control Study Lewis H. Kuller, Russell P. Tracy, Jessica Shaten et al. · American Journal of Epidemiology Open access 15 Sep 1996 1,105
21 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution MAGIC et al. · Nature Genetics 301 authors 10 Oct 2010 965
22 The Effect of Metformin and Intensive Lifestyle Intervention on the Metabolic Syndrome: The Diabetes Prevention Program Randomized Trial Trevor John Orchard, Marinella G. Temprosa, Ronald B Goldberg et al. · Annals of Internal Medicine Open access 19 Apr 2005 950
23 MEDICAL SCIENCE GISSI-2: A factorial randomised trial of alteplase versus streptokinase and heparin versus no heparin among 12 490 patients with acute myocardial infarction GRUPPOITALIANOPERLOSTUDIODELL · The Lancet Jul 1990 911
24 Predictive Value of Brachial Flow-Mediated Dilation for Incident Cardiovascular Events in a Population-Based Study Joseph Yeboah, Aaron R. Folsom, Gregory L. Burke et al. · Circulation Open access 28 Jul 2009 894
25 Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis Fabrizio De Benedetti et al. · New England Journal of Medicine Open access 19 Dec 2012 888
26 Effect of Systemic Glucocorticoids on Exacerbations of Chronic Obstructive Pulmonary Disease Dennis E. Niewoehner, Marcia L. Erbland, Robert H. Deupree et al. · New England Journal of Medicine Open access 24 Jun 1999 882
27 Ten-Year Mortality from Cardiovascular Disease in Relation to Cholesterol Level among Men with and without Preexisting Cardiovascular Disease Juha Pekkanen, Shai Linn, Gerardo Heiss et al. · New England Journal of Medicine Open access 14 Jun 1990 836
28 A Simplified Severity Scale for Age-Related Macular Degeneration Age-Related Eye Disease Study Research Group · Archives of Ophthalmology Open access Nov 2005 815
29 Outcomes in Patients with Acute Non–Q-Wave Myocardial Infarction Randomly Assigned to an Invasive as Compared with a Conservative Management Strategy William E. Boden, Robert A. O’Rourke, Michael H. Crawford et al. · New England Journal of Medicine Open access 18 Jun 1998 808
30 Clinical Use of Bone Densitometry Steven Ron Cummings, David Westfall Bates, Dennis M. Black · JAMA 16 Oct 2002 802
31 The Efficacy of Terazosin, Finasteride, or Both in Benign Prostatic Hyperplasia Herbert Lepor, William O. Williford, Michael J. Barry et al. · New England Journal of Medicine Open access 22 Aug 1996 801
32 Midlife and Late-Life Obesity and the Risk of Dementia Annette L. Fitzpatrick, Lewis H. Kuller, Oscar L. López et al. · Archives of Neurology Open access Mar 2009 798
33 Adjuvant Exemestane with Ovarian Suppression in Premenopausal Breast Cancer Olivia Pagani et al. · New England Journal of Medicine Open access Jun 2014 756
34 The Age-Related Eye Disease Study Severity Scale for Age-Related Macular Degeneration Age-Related Eye Disease Study Research Group · Archives of Ophthalmology Open access Nov 2005 745
35 Cardiovascular Mortality Risk in Chronic Kidney Disease Michael G. Shlipak, Linda F. Fried, Mary Cushman et al. · JAMA 12 Apr 2005 740
36 Changes in Plasma HIV-1 RNA and CD4+ Lymphocyte Counts and the Risk of Progression to AIDS William A. O’Brien, Pamela M. Hartigan, David E. Martin et al. · New England Journal of Medicine Open access 15 Feb 1996 737
37 Projecting the Number of Patients with End-Stage Renal Disease in the United States to the Year 2015 David T. Gilbertson, Jiannong Liu, Jay L. Xue et al. · Journal of the American Society of Nephrology 2 Nov 2005 722
38 Two Randomized Trials of Canakinumab in Systemic Juvenile Idiopathic Arthritis Nicolino Ruperto et al. · New England Journal of Medicine Open access 19 Dec 2012 722
39 Physical Fitness as a Predictor of Cardiovascular Mortality in Asymptomatic North American Men Lars‐Göran Ekelund, William L. Haskell, Jeffrey L. Johnson et al. · New England Journal of Medicine 24 Nov 1988 688
40 A Controlled Trial of Inpatient and Outpatient Geriatric Evaluation and Management Harvey Jay Cohen, John R. Feussner, Morris Weinberger et al. · New England Journal of Medicine 21 Mar 2002 663
41 Hemicraniectomy in Older Patients with Extensive Middle-Cerebral-Artery Stroke Eric Jüttler, Andreas Wilhelm Unterberg, Johannes Woitzik et al. · New England Journal of Medicine Open access 19 Mar 2014 626
42 Naltrexone in the Treatment of Alcohol Dependence John H. Krystal, Joyce A. Cramer, William F. Krol et al. · New England Journal of Medicine Open access 13 Dec 2001 620
43 Prospective Study of Coronary Heart Disease Incidence in Relation to Fasting Total Homocysteine, Related Genetic Polymorphisms, and B Vitamins Aaron R. Folsom, Francisco Javier Nieto, Paul Gerard McGovern et al. · Circulation Open access 21 Jul 1998 607
44 Office-Based Treatment of Opiate Addiction with a Sublingual-Tablet Formulation of Buprenorphine and Naloxone Paul J. Fudala, T. Peter Bridge, Susan Herbert et al. · New England Journal of Medicine Open access 3 Sep 2003 582
45 Long-term survival of medically treated patients in the Coronary Artery Surgery Study (CASS) Registry. Mary Jane Emond, Michael B. Mock, K B Davis et al. · Circulation Open access Dec 1994 556
46 Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women Yi‐Hsiang Hsu, Scott Alan Venners, Henry A Terwedow et al. · American Journal of Clinical Nutrition Open access 2006 549
47 Racial differences in response to therapy for heart failure: Analysis of the vasodilator-heart failure trials Peter E. Carson, Susan Ziesche, Gary R. Johnson et al. · Journal of Cardiac Failure Sep 1999 535
48 Carotenoid Content of U.S. Foods: An Update of the Database Joanne M. Holden, Alison L. Eldridge, Gary R. Beecher et al. · Journal of Food Composition and Analysis Sep 1999 533
49 Cost Effectiveness of Thrombolytic Therapy with Tissue Plasminogen Activator as Compared with Streptokinase for Acute Myocardial Infarction Daniel B. Mark, Mark Andrew Hlatky, Robert M. Califf et al. · New England Journal of Medicine Open access 25 May 1995 523
50 A Comparison of Clozapine and Haloperidol in Hospitalized Patients with Refractory Schizophrenia Robert Alan Rosenheck, Joyce A. Cramer, Weichun Xu et al. · New England Journal of Medicine Open access 18 Sep 1997 520

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.