Institution · TherapeuticsMD (United States)

Most cited papers from TherapeuticsMD (United States)

TherapeuticsMD (United States)

What are the most cited papers from TherapeuticsMD (United States)?

The most cited paper from TherapeuticsMD (United States) is "Dasatinib in Imatinib-Resistant Philadelphia Chromosome–Positive Leukemias" (Moshe Talpaz, Neil P. Shah, Hagop M. Kantarjian et al., 2006), with 1,789 citations. Next come "Size and shape effects in the biodistribution of intravascularly injected particles" (965) and "The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion" (362).

Published TypeFieldAccessCitations

Showing 50 of 60 papers. Every paper with more than 11 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Dasatinib in Imatinib-Resistant Philadelphia Chromosome–Positive Leukemias Moshe Talpaz, Neil P. Shah, Hagop M. Kantarjian et al. · New England Journal of Medicine Open access	14 Jun 2006	1,789
2	Size and shape effects in the biodistribution of intravascularly injected particles Paolo Decuzzi, Biana Godin, Takemi Tanaka et al. · Journal of Controlled Release	28 Oct 2009	965
3	The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion Mei Yee Koh, Robert Lemos, Xiuping Liu et al. · Cancer Research Open access	22 Apr 2011	362
4	The Women's EMPOWER Survey: Identifying Women's Perceptions on Vulvar and Vaginal Atrophy and Its Treatment Sheryl A. Kingsberg, Michael Krychman, Shelli Graham et al. · The Journal of Sexual Medicine Open access	12 Feb 2017	215
5	Landscape of DNA Virus Associations across Human Malignant Cancers: Analysis of 3,775 Cases Using RNA-Seq Joseph David Khoury, Nizar M. Tannir, Michelle D. Williams et al. · Journal of Virology Open access	6 Jun 2013	212
6	Increased Incidence of Endometrial Cancer Following the Women's Health Initiative: An Assessment of Risk Factors Ginger D. Constantine, Grant Kessler, Shelli Graham et al. · Journal of Women s Health Open access	28 Nov 2018	167
7	The association between Parkinson's disease and melanoma Tianhong Pan, Xinqun Li, Joseph J. Jankovic · International Journal of Cancer	4 Jan 2011	162
8	2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity Sherry Y. Wu et al. · Nature Communications Open access	12 Mar 2014	140
9	The Women's EMPOWER Survey: Women's Knowledge and Awareness of Treatment Options for Vulvar and Vaginal Atrophy Remains Inadequate Michael Krychman, Shelli Graham, Brian A. Bernick et al. · The Journal of Sexual Medicine Open access	12 Feb 2017	128
10	Systemic estradiol levels with low-dose vaginal estrogens Richard J. Santen, Sebastián Mirkin, Brian A. Bernick et al. · Menopause The Journal of The North American Menopause Society Open access	2 Dec 2019	124
11	A systematic review of the efficacy and safety of vaginal estrogen products for the treatment of genitourinary syndrome of menopause Colton Biehl, Olivia Plotsker, Sebastián Mirkin · Menopause The Journal of The North American Menopause Society Review	23 Oct 2018	118
12	Zearalenone Mycotoxin Affects Immune Mediators, MAPK Signalling Molecules, Nuclear Receptors and Genome-Wide Gene Expression in Pig Spleen Gina Cecilia Pistol, Cornelia Braicu, Monica Moțiu et al. · PLoS ONE Open access	26 May 2015	105
13	Selective estrogen receptor modulators (SERMs): A review of clinical data Sebastián Mirkin, James H. Pickar · Maturitas	24 Oct 2014	101
14	Behaviours and attitudes influencing treatment decisions for menopausal symptoms in five European countries Ginger D. Constantine, Shelli Graham, Cathy Clerinx et al. · Post Reproductive Health Open access	19 Feb 2016	90
15	Human vaginal pH and microbiota: an update Keshav Godha, Kelly M. Tucker, Colton Biehl et al. · Gynecological Endocrinology	22 Dec 2017	84
16	The REJOICE trial: a phase 3 randomized, controlled trial evaluating the safety and efficacy of a novel vaginal estradiol soft-gel capsule for symptomatic vulvar and vaginal atrophy Ginger D. Constantine, James A. Simon, James H. Pickar et al. · Menopause The Journal of The North American Menopause Society Open access	6 Dec 2016	84
17	Enhancing Chemotherapy Response with Bmi-1 Silencing in Ovarian Cancer Enfeng Wang, Sanjib Bhattacharyya, Annamária Szabolcs et al. · PLoS ONE Open access	21 Mar 2011	83
18	Computer-Aided Drug Discovery and Development Shuxing Zhang · Methods in molecular biology Book chapter	2011	78
19	Phase 1 study of an anti-CD33 immunotoxin, humanized monoclonal antibody M195 conjugated to recombinant gelonin (HUM-195/rGEL), in patients with advanced myeloid malignancies Gautam M. Borthakur, Michael G. Rosenblum, Moshe Talpaz et al. · Haematologica Open access	8 Aug 2012	73
20	WISDOM survey: attitudes and behaviors of physicians toward vulvar and vaginal atrophy (VVA) treatment in women including those with breast cancer history Sheryl A. Kingsberg, Lisa C. Larkin, Michael Krychman et al. · Menopause The Journal of The North American Menopause Society Open access	21 Aug 2018	54
21	TX-004HR vaginal estradiol has negligible to very low systemic absorption of estradiol David F. Archer, Ginger D. Constantine, James A. Simon et al. · Menopause The Journal of The North American Menopause Society Open access	20 Dec 2016	47
22	Endometrial safety of low-dose vaginal estrogens in menopausal women: a systematic evidence review Ginger D. Constantine, Shelli Graham, Kate L. Lapane et al. · Menopause The Journal of The North American Menopause Society Open access	26 Mar 2019	42
23	Vaginal pH: a simple assessment highly correlated with vaginal morphology and symptoms in postmenopausal women Kelly M. Tucker, Keshav Godha, Sebastián Mirkin et al. · Menopause The Journal of The North American Menopause Society	6 Mar 2018	40
24	Mesenchymal Chondrosarcoma: a Review with Emphasis on its Fusion-Driven Biology Marc El Beaino, Jason Roszik, John Andrew Livingston et al. · Current Oncology Reports	26 Mar 2018	40
25	Novel insight into triple-negative breast cancers, the emerging role of angiogenesis, and antiangiogenic therapy Cornelia Braicu, Roxana Chiorean, Alexandru Irimie et al. · Expert Reviews in Molecular Medicine	2016	40
26	The MATE survey: men's perceptions and attitudes towards menopause and their role in partners’ menopausal transition Sharon J. Parish, Stephanie S. Faubion, Marc S. Weinberg et al. · Menopause The Journal of The North American Menopause Society Open access	10 Jun 2019	39
27	Design of an EGFR-targeting toxin for photochemical delivery: in vitro and in vivo selectivity and efficacy Maria Brandal Berstad, Lawrence H. Cheung, Kristian Berg et al. · Oncogene	16 Feb 2015	38
28	Visual improvements in vaginal mucosa correlate with symptoms of VVA: data from a double-blind, placebo-controlled trial James A. Simon, David F. Archer, Risa Kagan et al. · Menopause The Journal of The North American Menopause Society Open access	18 Apr 2017	33
29	Pharmacokinetic studies of solubilized estradiol given vaginally in a novel softgel capsule James H. Pickar, Julia M. Amadio, Brian A. Bernick et al. · Climacteric Open access	9 Feb 2016	30
30	Relationship between vasomotor symptom improvements and quality of life and sleep outcomes in menopausal women treated with oral, combined 17β-estradiol/progesterone Sebastián Mirkin, Shelli Graham, Dennis A. Revicki et al. · Menopause The Journal of The North American Menopause Society Open access	31 Dec 2018	29
31	17β-Estradiol and natural progesterone for menopausal hormone therapy: REPLENISH phase 3 study design of a combination capsule and evidence review Sebastián Mirkin, Julia M. Amadio, Brian A. Bernick et al. · Maturitas Open access	9 Mar 2015	28
32	Endometrial safety and bleeding profile of a 17β-estradiol/progesterone oral softgel capsule (TX-001HR)∗ Sebastián Mirkin, Steven Robert Goldstein, David F. Archer et al. · Menopause The Journal of The North American Menopause Society Open access	8 Jan 2020	26
33	Evaluation of clinical meaningfulness of estrogen plus progesterone oral capsule (TX-001HR) on moderate to severe vasomotor symptoms Ginger D. Constantine, Dennis A. Revicki, Risa Kagan et al. · Menopause The Journal of The North American Menopause Society Open access	4 Dec 2018	25
34	Evidence on the use of progesterone in menopausal hormone therapy Sebastián Mirkin · Climacteric Open access	9 Apr 2018	23
35	A vaginal estradiol softgel capsule, TX-004HR, has negligible to very low systemic absorption of estradiol: Efficacy and pharmacokinetic data review James A. Simon, David F. Archer, Ginger D. Constantine et al. · Maturitas Open access	16 Feb 2017	23
36	Metabolic and cardiovascular effects of TX-001HR in menopausal women with vasomotor symptoms Roger A. Lobo, Andrew M. Kaunitz, Nanette F. Santoro et al. · Climacteric Open access	31 Jul 2019	22
37	Improvement in sleep outcomes with a 17β-estradiol–progesterone oral capsule (TX-001HR) for postmenopausal women Risa Kagan, Ginger D. Constantine, Andrew M. Kaunitz et al. · Menopause The Journal of The North American Menopause Society Open access	21 Dec 2018	22
38	Oral 17β-estradiol/progesterone (TX-001HR) and quality of life in postmenopausal women with vasomotor symptoms James A. Simon, Andrew M. Kaunitz, Robin Kroll et al. · Menopause The Journal of The North American Menopause Society Open access	26 Nov 2018	22
39	Initial results of phase I study of DCC-2618, a broad-spectrum KIT and PDGFRa inhibitor, in patients (pts) with gastrointestinal stromal tumor (GIST) by number of prior regimens Suzanne George, Michael Charles Heinrich, Ping Chi et al. · Annals of Oncology Open access	Oct 2018	22
40	Review of menopausal hormone therapy with estradiol and progesterone versus other estrogens and progestins Shelli Graham, David F. Archer, James A. Simon et al. · Gynecological Endocrinology Open access	8 Sep 2022	21
41	The utility of measuring anti-Müllerian hormone in predicting menopause B. Aydogan, Sebastián Mirkin · Climacteric	7 Apr 2015	20
42	Intravenous Forodesine (BCX-1777), a Novel Purine Nucleoside Phosphorylase (PNP) Inhibitor, Demonstrates Clinical Activity in Phase I/II Studies in Patients with B-Cell Acute Lymphoblastic Leukemia. Richard R. Furman, Varsha V. Gandhi, John C. Bennett et al. · Blood	16 Nov 2004	19
43	TX-004HR Improves Sexual Function as Measured by the Female Sexual Function Index in Postmenopausal Women with Vulvar and Vaginal Atrophy: The REJOICE Trial Sheryl A. Kingsberg, Leonard R. Derogatis, James A. Simon et al. · The Journal of Sexual Medicine Open access	Oct 2016	19
44	A randomized, double-blind, placebo-controlled phase 2 pilot trial evaluating a novel, vaginal softgel capsule containing solubilized estradiol James H. Pickar, Julia M. Amadio, John M. Hill et al. · Menopause The Journal of The North American Menopause Society Open access	2 Feb 2016	18
45	Exploring the safety, effect on the tumor microenvironment, and efficacy of itacitinib in combination with epacadostat or parsaclisib in advanced solid tumors: a phase I study Aung Naing, John D. Powderly, John J. Nemunaitis et al. · Journal for ImmunoTherapy of Cancer Open access	Mar 2022	17
46	Uterine bleeding with hormone therapies in menopausal women: a systematic review James H. Pickar, David F. Archer, Steven Robert Goldstein et al. · Climacteric ReviewOpen access	7 Sep 2020	17
47	TX-001HR is associated with a clinically meaningful effect on severity of moderate to severe vasomotor symptoms in the REPLENISH trial Ginger D. Constantine, James A. Simon, Andrew M. Kaunitz et al. · Menopause The Journal of The North American Menopause Society Open access	13 Jul 2020	17
48	Effects of Estradiol Dose and Serum Estradiol Levels on Metabolic Measures in Early and Late Postmenopausal Women in the REPLENISH Trial Intira Sriprasert, Howard N. Hodis, Brian A. Bernick et al. · Journal of Women s Health Open access	9 Jul 2020	17
49	Update on the phase II SUMMIT trial: Neratinib + fulvestrant for HER2-mutant, HR-positive, metastatic breast cancer Lillian Mary Smyth, Cristina Saura, Sarina Anne Piha-Paul et al. · Annals of Oncology Open access	May 2019	17
50	Determination of estradiol and progesterone content in capsules and creams from compounding pharmacies Frank Z. Stanczyk, Chunying Niu, Colleen G. Azen et al. · Menopause The Journal of The North American Menopause Society Open access	3 Jun 2019	16

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.