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Most cited papers from TiFN

What are the most cited papers from TiFN?

The most cited paper from TiFN is "Review article: the role of butyrate on colonic function" (Henrike M. Hamer, Daisy M.A.E. Jonkers, Koen Venema et al., 2007), with 2,777 citations. Next come "Population-level analysis of gut microbiome variation" (2,527) and "The gut microbiota and host health: a new clinical frontier" (2,357).

Showing 50 of 60 papers. Every paper with more than 329 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Review article: the role of butyrate on colonic function Henrike M. Hamer, Daisy M.A.E. Jonkers, Koen Venema et al. · Alimentary Pharmacology & Therapeutics Open access 26 Oct 2007 2,777
2 Population-level analysis of gut microbiome variation Gwen Falony et al. · Science Open access 28 Apr 2016 2,527
3 The gut microbiota and host health: a new clinical frontier Julian Roberto Marchesi, David Adams, Francesca Fava et al. · Gut Open access 2 Sep 2015 2,357
4 Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity Alexandra Zhernakova et al. · Science Open access 28 Apr 2016 2,024
5 Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans Silvie Timmers, Ellen Konings, Lena Bilet et al. · Cell Metabolism Open access Nov 2011 1,320
6 Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation Gijs den Besten, Aycha Bleeker, Albert Gerding et al. · Diabetes 18 Feb 2015 1,130
7 Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice Amandine Everard, Vladimir Lazarević, Muriel Derrien et al. · Diabetes Open access 21 Sep 2011 1,080
8 Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition Ruud S. Kootte et al. · Cell Metabolism Open access Oct 2017 1,051
9 Potent Competitive Interactions of Some Brominated Flame Retardants and Related Compounds with Human Transthyretin in Vitro Ilonka A.T.M. Meerts · Toxicological Sciences Open access Jul 2000 905
10 The effect of host genetics on the gut microbiome Marc Jan Bonder et al. · Nature Genetics Open access 3 Oct 2016 883
11 Stress Physiology of Lactic Acid Bacteria Konstantinos Papadimitriou, Ángel Alegría, Peter A. Bron et al. · Microbiology and Molecular Biology Reviews ReviewOpen access 27 Jul 2016 878
12 The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids Jingyuan Fu, Marc Jan Bonder, María Carmen Cénit et al. · Circulation Research Open access 8 Oct 2015 794
13 The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates Erwin G. Zoetendal, Jeroen Raes, Bartholomeus van den Bogert et al. · The ISME Journal Open access 19 Jan 2012 734
14 Shifts in growth strategies reflect tradeoffs in cellular economics Douwe Molenaar, Rogier van Berlo, Dick de Ridder et al. · Molecular Systems Biology Open access 3 Nov 2009 726
15 Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier Jurgen M. Karczewski, Freddy J. Troost, Irene Konings et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology Open access 11 Mar 2010 679
16 High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota Erwin G. Zoetendal, Mirjana D. Rajilić-Stojanović, Willem M. de Vos · Gut Open access 21 Oct 2008 669
17 The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity Rinke Stienstra, Leo A. B. Joosten, Tim B. Koenen et al. · Cell Metabolism Open access Dec 2010 669
18 Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms Saad Al-Lahham, Maikel Petrus Peppelenbosch, Han Roelofsen et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 6 Aug 2010 624
19 Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila Muriel Derrien, Peter van Baarlen, Guido J. E. J. Hooiveld et al. · Frontiers in Microbiology Open access 2011 613
20 Epithelial crosstalk at the microbiota–mucosal interface Jerry Mark Wells, Oriana Rossi, Marjolein Meijerink et al. · Proceedings of the National Academy of Sciences Open access 8 Sep 2010 589
21 Dietary Protein, Weight Loss, and Weight Maintenance Margriet S. Westerterp‐Plantenga, Arie G. Nieuwenhuizen, Daniel Tomé et al. · Annual Review of Nutrition ReviewOpen access 12 Jun 2009 576
22 The significance of genic balance to endosperm development in interspecific crosses S. A. Johnston, Ton P. M. den Nijs, Stanley J. Peloquin et al. · Theoretical and Applied Genetics Open access 1980 575
23 Mucin-bacterial interactions in the human oral cavity and digestive tract Muriel Derrien, Mark W. J. van Passel, Jeroen H.B. van de Bovenkamp et al. · Gut Microbes Open access Jul 2010 565
24 Protein Supplementation Increases Muscle Mass Gain During Prolonged Resistance-Type Exercise Training in Frail Elderly People: A Randomized, Double-Blind, Placebo-Controlled Trial Michael Tieland, Marlou L. Dirks, Nikita van der Zwaluw et al. · Journal of the American Medical Directors Association Open access 6 Jul 2012 563
25 Saliva as research material: Biochemical, physicochemical and practical aspects Raymond G. Schipper, Erika Silletti, Monique H. Vingerhoeds · Archives of Oral Biology Open access 11 Aug 2007 534
26 Identification of selected seaweed polysaccharides (phycocolloids) by vibrational spectroscopy (FTIR-ATR and FT-Raman) Leonel Pereira, Ana Margarida Amado, Alan Trevor Critchley et al. · Food Hydrocolloids Open access 5 Dec 2008 517
27 A Novel Approach for Nontargeted Data Analysis for Metabolomics. Large-Scale Profiling of Tomato Fruit Volatiles Yury M. Tikunov, Arjen Lommen, C. H. Ric De Vos et al. · PLANT PHYSIOLOGY Open access Nov 2005 516
28 Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease Emma Gerrits, Nieske Brouwer, Susanne M. Kooistra et al. · Acta Neuropathologica Open access 20 Feb 2021 506
29 Lipid accumulation in non-adipose tissue and lipotoxicity Noud A. van Herpen, Vera B. Schrauwen‐Hinderling · Physiology & Behavior Open access 6 Dec 2007 499
30 Regenerative agriculture – the soil is the base Loekie Schreefel, Rogier P.O. Schulte, I.J.M. de Boer et al. · Global Food Security Open access 6 Aug 2020 490
31 Consumer response to packaging design: The role of packaging materials and graphics in sustainability perceptions and product evaluations Nigel Desmond Steenis, Erica van Herpen, Ivo A. van der Lans et al. · Journal of Cleaner Production Open access 6 Jun 2017 490
32 Patients With Type 2 Diabetes Show a Greater Decline in Muscle Mass, Muscle Strength, and Functional Capacity With Aging Marika Leenders, Lex B. Verdijk, L. van der Hoeven et al. · Journal of the American Medical Directors Association 26 Mar 2013 489
33 Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon Noortje Ijssennagger, Clara Belzer, Guido J. E. J. Hooiveld et al. · Proceedings of the National Academy of Sciences Open access 27 Jul 2015 459
34 Kupffer Cells Promote Hepatic Steatosis Via Interleukin-1β–Dependent Suppression of Peroxisome Proliferator-Activated Receptor α Activity Rinke Stienstra, Fredy Z. Saudale, Caroline Duval et al. · Hepatology Open access 29 Sep 2009 451
35 Microbial stress response in minimal processing Tjakko Abee · International Journal of Food Microbiology Open access 15 Sep 1999 447
36 Saturated fat stimulates obesity and hepatic steatosis and affects gut microbiota composition by an enhanced overflow of dietary fat to the distal intestine Nicole J. W. de Wit, Muriel Derrien, Hanneke Bosch-Vermeulen et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology Open access 15 Jun 2012 436
37 Butyrate modulates oxidative stress in the colonic mucosa of healthy humans Henrike M. Hamer, Daisy M.A.E. Jonkers, Aalt Bast et al. · Clinical Nutrition 24 Dec 2008 407
38 Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice Floris Fransen, Adriaan A. van Beek, Theo Borghuis et al. · Frontiers in Immunology Open access 23 Oct 2017 404
39 The pro-oxidant chemistry of the natural antioxidants vitamin C, vitamin E, carotenoids and flavonoids Ivonne M.C.M. Rietjens, Marelle G. Boersma, Laura de Haan et al. · Environmental Toxicology and Pharmacology Open access Jul 2002 403
40 The Biological Relevance of Direct Antioxidant Effects of Polyphenols for Cardiovascular Health in Humans Is Not Established1–4 Peter C.H. Hollman, Aedín Cassidy, Blandine Comte et al. · Journal of Nutrition Open access 30 Mar 2011 402
41 Differential NF-κB pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance Peter van Baarlen, Freddy J. Troost, Saskia van Hemert et al. · Proceedings of the National Academy of Sciences Open access 3 Feb 2009 387
42 Short chain fatty acids exchange across the gut and liver in humans measured at surgery Johanne G. Bloemen, Koen Venema, Marcel C.G. van de Poll et al. · Clinical Nutrition 12 Jun 2009 386
43 Microbiota conservation and BMI signatures in adult monozygotic twins Sebastian Tims, Catherine A Derom, Daisy M.A.E. Jonkers et al. · The ISME Journal Open access 29 Nov 2012 385
44 The extracellular biology of the lactobacilli Michiel Kleerebezem, Pascal Hols, Elvis Bernard et al. · FEMS Microbiology Reviews Open access 21 Dec 2009 382
45 Effect of fish oil on cognitive performance in older subjects Ondine van de Rest, Johanna Marianne Geleijnse, Frans J. Kok et al. · Neurology Open access 4 Aug 2008 382
46 Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein René Koopman, Nico Crombach, Annemie P. Gijsen et al. · American Journal of Clinical Nutrition Open access 27 May 2009 380
47 The proteolytic system of lactic acid bacteria revisited: a genomic comparison Mengjin Liu, Jumamurat R. Bayjanov, Bernadet Renckens et al. · BMC Genomics Open access 2010 376
48 Understanding the role of tryptophan and serotonin metabolism in gastrointestinal function Dániel Keszthelyi, Freddy J. Troost, Ad Masclee · Neurogastroenterology & Motility 28 Jul 2009 373
49 Production of Aroma Compounds in Lactic Fermentations Eddy J. Smid, Michiel Kleerebezem · Annual Review of Food Science and Technology ReviewOpen access 28 Feb 2014 363
50 Exercise-Induced Splanchnic Hypoperfusion Results in Gut Dysfunction in Healthy Men Kim van Wijck, Kaatje Lenaerts, Luc J. C. van Loon et al. · PLoS ONE Open access 21 Jul 2011 359

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.