| 1 |
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al. · Autophagy
Open access2,467 authors |
2 Jan 2016 |
6,023 |
| 2 |
Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species
Koji Atarashi, Takeshi Tanoue, Tatsuichiro Shima et al. · Science
Open access |
23 Dec 2010 |
3,724 |
| 3 |
Consensus statement on concussion in sport—the 5 th international conference on concussion in sport held in Berlin, October 2016
Paul Robert McCrory et al. · British Journal of Sports Medicine
|
26 Apr 2017 |
3,354 |
| 4 |
YET ANOTHER CHAOTIC ATTRACTOR
Guanrong Chen, Tetsushi Ueta · International Journal of Bifurcation and Chaos
Open access |
Jul 1999 |
2,832 |
| 5 |
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
Shin Yoshimoto, Tze Mun Loo, Koji Atarashi et al. · Nature
|
25 Jun 2013 |
2,234 |
| 6 |
Response of plants to water stress
Yuriko Osakabe, Keishi Osakabe, Kazuo Shinozaki et al. · Frontiers in Plant Science
Open access |
13 Mar 2014 |
1,619 |
| 7 |
Ubiquitin is phosphorylated by PINK1 to activate parkin
Fumika Koyano, Kei Okatsu, Hidetaka Kosako et al. · Nature
|
30 Apr 2014 |
1,522 |
| 8 |
Influence of interhemispheric interactions on motor function in chronic stroke
Nagako Murase, Julie Agatha Vásquez Duque, Riccardo Mazzocchio et al. · Annals of Neurology
|
3 Feb 2004 |
1,490 |
| 9 |
Mutations of optineurin in amyotrophic lateral sclerosis
Hirofumi Maruyama et al. · Nature
|
28 Apr 2010 |
1,274 |
| 10 |
A Slicer-Mediated Mechanism for Repeat-Associated siRNA 5' End Formation in Drosophila
Lalith S. Gunawardane, Kuniaki Saito, Kazumichi M. Nishida et al. · Science
|
22 Feb 2007 |
1,229 |
| 11 |
Electrodiagnostic criteria for diagnosis of ALS
Mamede A. de Carvalho, Reinhard Dengler, Andrew Eisen et al. · Clinical Neurophysiology
|
9 Feb 2008 |
1,204 |
| 12 |
Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning
Tatsuya Yoshizawa, Yuki Handa, Yoshikatsu Uematsu et al. · Nature Genetics
|
Aug 1997 |
1,184 |
| 13 |
Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
Toshikazu Nakamura, Katsuhiko Nawa, Akira Ichihara · Biochemical and Biophysical Research Communications
|
Aug 1984 |
1,150 |
| 14 |
Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)
Yoshikatsu Kanai, Hiroko Segawa, Ken‐ichi Miyamoto et al. · Journal of Biological Chemistry
Open access |
Sep 1998 |
1,119 |
| 15 |
Genome evolution in the allotetraploid frog Xenopus laevis
Adam M. Session et al. · Nature
Open access |
Oct 2016 |
1,066 |
| 16 |
Tuning arousal with optogenetic modulation of locus coeruleus neurons
Matthew E. Carter, Ofer Yizhar, Sachiko Chikahisa et al. · Nature Neuroscience
Open access |
31 Oct 2010 |
1,053 |
| 17 |
Search for Majorana Neutrinos Near the Inverted Mass Hierarchy Region with KamLAND-Zen
A. Gando et al. · Physical Review Letters
Open access |
16 Aug 2016 |
994 |
| 18 |
Degenerative Disorders of the Temporomandibular Joint: Etiology, Diagnosis, and Treatment
Eiji I. Tanaka, Michael S. Detamore, Louis Gerard Mercuri · Journal of Dental Research
|
Apr 2008 |
954 |
| 19 |
A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application
Taku Okazaki, Shunsuke Chikuma, Yoshiko Iwai et al. · Nature Immunology
Open access |
15 Nov 2013 |
931 |
| 20 |
Design concepts for the Cherenkov Telescope Array CTA: an advanced facility for ground-based high-energy gamma-ray astronomy
Marcos Daniel Actis et al. · Experimental Astronomy
Open access672 authors |
22 Nov 2011 |
921 |
| 21 |
p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload
Masanori Sano, Tohru Minamino, Haruhiro Toko et al. · Nature
|
Mar 2007 |
908 |
| 22 |
Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells
Masako Tada, Yousuke Takahama, Kuniya Abe et al. · Current Biology
Open access |
Oct 2001 |
884 |
| 23 |
Comparative Metagenomics Revealed Commonly Enriched Gene Sets in Human Gut Microbiomes
Ken Kurokawa, Takehiko Itoh, Tomomi Kuwahara et al. · DNA Research
Open access |
2007 |
866 |
| 24 |
Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways
Katsutomo Okamura, Akira Ishizuka, Haruhiko Siomi et al. · Genes & Development
Open access |
Jul 2004 |
847 |
| 25 |
Comparative release of growth factors from PRP, PRF, and advanced-PRF
Eizaburo Kobayashi, Laura Flückiger, Masako Fujioka‐Kobayashi et al. · Clinical Oral Investigations
Open access |
24 Jan 2016 |
819 |
| 26 |
Therapy for thymic epithelial tumors: a clinical study of 1,320 patients from Japan
Kazuya Kondo, Yasumasa Monden · The Annals of Thoracic Surgery
Open access |
Sep 2003 |
811 |
| 27 |
An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy
Kazuhiro Kobayashi, Yutaka Nakahori, Masashi Miyake et al. · Nature
|
Jul 1998 |
811 |
| 28 |
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
Kazuki Yasuda et al. · Nature Genetics
|
17 Aug 2008 |
778 |
| 29 |
ATP-sensitive K+ channel in the mitochondrial inner membrane
Isao Inoue, Hideki Nagase, Kuki Kishi et al. · Nature
|
Jul 1991 |
754 |
| 30 |
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines
Osamu Yanagida, Yoshikatsu Kanai, Arthit Chairoungdua et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes
Open access |
Oct 2001 |
754 |
| 31 |
Femtosecond laser-assisted three-dimensional microfabrication in silica
Andrius Marcinkevičius, Saulius Juodkazis, Mitsuru Watanabe et al. · Optics Letters
Open access |
Mar 2001 |
742 |
| 32 |
Identification of Human Plasma Lysophospholipase D, a Lysophosphatidic Acid-producing Enzyme, as Autotaxin, a Multifunctional Phosphodiesterase
Akira Tokumura, Eiji Majima, Yuko Kariya et al. · Journal of Biological Chemistry
Open access |
Oct 2002 |
741 |
| 33 |
Journey through the thymus: stromal guides for T-cell development and selection
Yousuke Takahama · Nature reviews. Immunology
Review |
Feb 2006 |
739 |
| 34 |
Improving polygenic prediction in ancestrally diverse populations
Yunfeng Ruan et al. · Nature Genetics
Open access |
May 2022 |
733 |
| 35 |
Multitargeted cancer prevention by quercetin
Akira Murakami, Hitoshi Ashida, Junji Terao · Cancer Letters
|
8 May 2008 |
723 |
| 36 |
Introducing the CTA concept
B. S. Acharya et al. · Astroparticle Physics
Open access976 authors |
9 Feb 2013 |
717 |
| 37 |
The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage
Amr Selim Abu Lila, Hiroshi Kiwada, Tatsuhiro Ishida · Journal of Controlled Release
|
7 Aug 2013 |
717 |
| 38 |
Novel biomarkers for pre‐diabetes identified by metabolomics
Rui Wang‐Sattler et al. · Molecular Systems Biology
Open access |
25 Sep 2012 |
713 |
| 39 |
Management of Hepatocellular Carcinoma in Japan: JSH Consensus Statements and Recommendations 2021 Update
Masatoshi Kudo et al. · Liver Cancer
Open access |
2021 |
689 |
| 40 |
Spontaneous Long-Term Hyperglycemic Rat With Diabetic Complications: Otsuka Long-Evans Tokushima Fatty (OLETF) Strain
Kazuya Kawano, Tsukasa Hirashima, Shigehito Mori et al. · Diabetes
|
Nov 1992 |
687 |
| 41 |
Circulating Skeletal Stem Cells
Sergei A. Kuznetsov, Mahesh H. Mankani, Stan Gronthos et al. · The Journal of Cell Biology
Open access |
28 May 2001 |
685 |
| 42 |
Anti-PEG antibodies: Properties, formation, testing and role in adverse immune reactions to PEGylated nano-biopharmaceuticals
Gergely Tibor Kozma, Taro Shimizu, Tatsuhiro Ishida et al. · Advanced Drug Delivery Reviews
ReviewOpen access |
2020 |
677 |
| 43 |
Tumor cell expression of programmed cell death‐1 ligand 1 is a prognostic factor for malignant melanoma
Ryosuke Hino, Kenji Kabashima, Yu Kato et al. · Cancer
Open access |
8 Feb 2010 |
670 |
| 44 |
A small peptide modulates stomatal control via abscisic acid in long-distance signalling
Fuminori Takahashi, Takehiro Suzuki, Yuriko Osakabe et al. · Nature
|
29 Mar 2018 |
669 |
| 45 |
Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome
Kuniaki Saito, Kazumichi M. Nishida, Tomoko Mori et al. · Genes & Development
Open access |
Aug 2006 |
662 |
| 46 |
A Vitamin D Receptor Gene Polymorphism in the Translation Initiation Codon: Effect on Protein Activity and Relation to Bone Mineral Density in Japanese Women
Hidekazu Arai, Ken‐ichi Miyamoto, Yutaka Taketani et al. · Journal of Bone and Mineral Research
|
Jun 1997 |
656 |
| 47 |
Transcriptional Roles of Nuclear Factor κB and Nuclear Factor-Interleukin-6 in the Tumor Necrosis Factor α-Dependent Induction of Cyclooxygenase-2 in MC3T3-E1 Cells
Kei Yamamoto, Kei Yamamoto, Toshiya Arakawa et al. · Journal of Biological Chemistry
Open access |
Dec 1995 |
654 |
| 48 |
Effects of Extracranial–Intracranial Bypass for Patients With Hemorrhagic Moyamoya Disease
Susumu Miyamoto et al. · Stroke
Open access |
25 Mar 2014 |
652 |
| 49 |
Neutrophils in tissue injury and repair
Jing Wang · Cell and Tissue Research
Open access |
30 Jan 2018 |
649 |
| 50 |
Hepatocyte Growth Factor Induces Gefitinib Resistance of Lung Adenocarcinoma with Epidermal Growth Factor Receptor–Activating Mutations
Seiji Yano, Wei Wang, Qi Li et al. · Cancer Research
Open access |
14 Nov 2008 |
646 |