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Most cited papers from Toranomon Hospital

What are the most cited papers from Toranomon Hospital?

The most cited paper from Toranomon Hospital is "The International HapMap Project" (Richard A. Gibbs et al., 2003), with 6,187 citations. Next come "Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial" (5,578) and "A cross-population atlas of genetic associations for 220 human phenotypes" (2,484).

Showing 50 of 59 papers. Every paper with more than 398 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The International HapMap Project Richard A. Gibbs et al. · Nature Open access183 authors 18 Dec 2003 6,187
2 Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial Masatoshi Kudo et al. · The Lancet Open access Mar 2018 5,578
3 A cross-population atlas of genetic associations for 220 human phenotypes Saori Sakaue et al. · Nature Genetics Open access 30 Sep 2021 2,484
4 Definition and diagnostic criteria of clinical obesity Francesco Rubino et al. · The Lancet Diabetes & Endocrinology Open access 14 Jan 2025 1,660
5 Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial Thomas B. Powles et al. · The Lancet Open access 18 Dec 2017 1,437
6 A systematic review of waist-to-height ratio as a screening tool for the prediction of cardiovascular disease and diabetes: 0·5 could be a suitable global boundary value Lucy M. Browning, Shiun Dong Hsieh, Margaret Ashwell · Nutrition Research Reviews ReviewOpen access 7 Sep 2010 1,413
7 Gene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma Yujin Hoshida et al. · New England Journal of Medicine Open access 16 Oct 2008 1,318
8 Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma Yujin Hoshida, Sebastian M. B. Nijman, Masahiro Kobayashi et al. · Cancer Research Open access Sep 2009 1,252
9 Phase Ib Study of Lenvatinib Plus Pembrolizumab in Patients With Unresectable Hepatocellular Carcinoma Richard S. Finn, Masafumi Ikeda, Andrew Xiuxuan Zhu et al. · Journal of Clinical Oncology Open access 27 Jul 2020 1,188
10 Six reasons why the waist-to-height ratio is a rapid and effective global indicator for health risks of obesity and how its use could simplify the international public health message on obesity Margaret Ashwell, Shiun Dong Hsieh · International Journal of Food Sciences and Nutrition 2005 1,086
11 The Development and Validation of an Endoscopic Grading System for Barrett’s Esophagus: The Prague C & M Criteria Prateek Sharma, John Dent, David G. Armstrong et al. · Gastroenterology Open access 17 Aug 2006 1,055
12 A proposed system for the nomenclature of hepatitis C viral genotypes Peter Simmonds et al. · Hepatology May 1994 1,024
13 Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region Fumihiko Ishikawa, Shuro Yoshida, Yoriko Saito et al. · Nature Biotechnology 21 Oct 2007 1,000
14 Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis Qing Ye, Biyao Zou, Yee Hui Yeo et al. · ˜The œLancet. Gastroenterology & hepatology Review 12 May 2020 929
15 Radical Lymph Node Dissection for Cancer of the Thoracic Esophagus Hiroshi Akiyama, Masahiko Tsurumaru, Harushi Udagawa et al. · Annals of Surgery Open access Sep 1994 907
16 Molecular motors and mechanisms of directional transport in neurons Nobutaka Hirokawa, Reiko Takemura · Nature reviews. Neuroscience Review 15 Feb 2005 840
17 Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation Anubha Mahajan et al. · Nature Genetics Open access354 authors May 2022 774
18 Population-averaged atlas of the macroscale human structural connectome and its network topology Fang-Cheng F. Yeh, Sandip S. Panesar, David Douglas de Sousa Fernandes et al. · NeuroImage Open access 24 May 2018 725
19 Long-term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection Tetsuya Hosaka, Fumitaka Suzuki, Masahiro Kobayashi et al. · Hepatology Open access 5 Dec 2012 715
20 Management of Hepatocellular Carcinoma in Japan: JSH Consensus Statements and Recommendations 2021 Update Masatoshi Kudo et al. · Liver Cancer Open access 2021 689
21 Prevention of type 2 diabetes by lifestyle intervention: a Japanese trial in IGT males Kinori Kosáka, Mitsuhiko Noda, Takeshi Kuzuya · Diabetes Research and Clinical Practice 29 Sep 2004 661
22 Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers Keisuke Kataoka et al. · Nature 21 May 2016 653
23 Somatic RHOA mutation in angioimmunoblastic T cell lymphoma Mamiko Sakata‐Yanagimoto et al. · Nature Genetics 12 Jan 2014 653
24 A multivariate analysis of risk factors for hepatocellular carcinogenesis: A prospective observation of 795 patients with viral and alcoholic cirrhosis Kenji Ikeda · Hepatology Open access Jul 1993 627
25 Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in HER2-Positive Metastatic Breast Cancer Previously Treated With ≥ 2 HER2-Directed Regimens: Phase III NALA Trial Cristina Saura et al. · Journal of Clinical Oncology Open access 17 Jul 2020 616
26 KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria Masaomi Nangaku, Reiko Sato-Yoshitake, Yasushi Okada et al. · Cell Dec 1994 601
27 Takayasu's Arteritis Kiku Nakao, Masao Ikeda, Shinichi Kimata et al. · Circulation Jun 1967 601
28 Genetic drivers of heterogeneity in type 2 diabetes pathophysiology Ken Suzuki et al. · Nature Open access369 authors 19 Feb 2024 598
29 Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy Akinori Kimura et al. · Nature Genetics Aug 1997 580
30 Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma Masatoshi Kudo et al. · European Journal of Cancer 21 Jun 2011 578
31 Hypertrophic nonobstructive cardiomyopathy with giant negative T waves (apical hypertrophy): Ventriculographic and echocardiographic features in 30 patients Hiroshi Yamaguchi, Takao Ishimura, Shinichiro Nishiyama et al. · The American Journal of Cardiology Sep 1979 568
32 Redefining the elderly as aged 75 years and older: Proposal from the Joint Committee of Japan Gerontological Society and the Japan Geriatrics Society Yasuyoshi Ouchi, Hiromi Rakugi, Hidenori Arai et al. · Geriatrics and gerontology international/Geriatrics & gerontology international Jul 2017 564
33 Effect of Mechanical Thrombectomy Without vs With Intravenous Thrombolysis on Functional Outcome Among Patients With Acute Ischemic Stroke Kentaro Suzuki et al. · JAMA Open access 19 Jan 2021 557
34 Estimation of glomerular filtration rate by the MDRD study equation modified for Japanese patients with chronic kidney disease Enyu Imai et al. · Clinical and Experimental Nephrology 23 Mar 2007 544
35 Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection Hiromitsu Kumada et al. · Hepatology Open access 6 Mar 2014 539
36 Prevalence of chronic kidney disease in the Japanese general population Enyu Imai, Masaru Horio, Tsuyoshi Watanabe et al. · Clinical and Experimental Nephrology 10 Jun 2009 536
37 Respiratory Viral Infection-Induced Microbiome Alterations and Secondary Bacterial Pneumonia Shigeo Hanada, Mina Pirzadeh, Kyle Y. Carver et al. · Frontiers in Immunology Open access 16 Nov 2018 533
38 Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma Yuichiro� Doki et al. · UCL Discovery (University College London) Open access 3 Feb 2022 532
39 A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians Yoichiro Kamatani, Sukanya Wattanapokayakit, Hidenori Ochi et al. · Nature Genetics 6 Apr 2009 526
40 Effects of Oral Branched-Chain Amino Acid Granules on Event-Free Survival in Patients With Liver Cirrhosis Yasutoshi Muto, Shunichi Sato, Akiharu Watanabe et al. · Clinical Gastroenterology and Hepatology Jul 2005 510
41 Neoadjuvant (Chemo)radiotherapy With Total Mesorectal Excision Only Is Not Sufficient to Prevent Lateral Local Recurrence in Enlarged Nodes: Results of the Multicenter Lateral Node Study of Patients With Low cT3/4 Rectal Cancer Atsushi Ogura, Tsuyoshi Konishi, Chris Cunningham et al. · Journal of Clinical Oncology Open access 7 Nov 2018 506
42 Combining Clinical, Pathology, and Gene Expression Data to Predict Recurrence of Hepatocellular Carcinoma Augusto García Villanueva, Yujin Hoshida, Carlo Battiston et al. · Gastroenterology Open access 13 Feb 2011 468
43 Effect of Interferon Therapy on Hepatocellular Carcinogenesis in Patients With Chronic Hepatitis Type C: A Long–Term Observation Study of 1,643 Patients Using Statistical Bias Correction With Proportional Hazard Analysis Kenji Ikeda, Satoshi Saitoh, Yasuji Arase et al. · Hepatology Open access Apr 1999 468
44 Identification of Therapeutic Targets for Quiescent, Chemotherapy-Resistant Human Leukemia Stem Cells Yoriko Saito, Hiroshi Kitamura, Atsushi Hijikata et al. · Science Translational Medicine Open access 3 Feb 2010 464
45 Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial Josep Maria Llovet et al. · The Lancet Oncology Open access209 authors 28 Nov 2023 455
46 Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma Shlomi Finkin et al. · Nature Immunology Open access 26 Oct 2015 451
47 Gut microbial carbohydrate metabolism contributes to insulin resistance Tadashi Takeuchi et al. · Nature Open access 30 Aug 2023 450
48 Role of Insulin Resistance in MAFLD Yoshitaka Sakurai, Naoto Kubota, Toshimasa Yamauchi et al. · International Journal of Molecular Sciences Open access 16 Apr 2021 447
49 Factors predictive of response to interferon-α therapy in hepatitis C virus infection Akihito Tsubota · Hepatology Open access May 1994 444
50 Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients Kenji Ikeda, Satoshi Saitoh, Yoshiyuki Suzuki et al. · Journal of Hepatology Jun 1998 435

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.