| 1 |
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al. · Autophagy
Open access2,467 authors |
2 Jan 2016 |
6,023 |
| 2 |
Nuclear ribosomal internal transcribed spacer (ITS) region as a universal DNA barcode marker for Fungi
Conrad L. Schoch et al. · Proceedings of the National Academy of Sciences
Open access156 authors |
27 Mar 2012 |
5,240 |
| 3 |
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial
Tetsuya Mitsudomi et al. · The Lancet Oncology
|
19 Dec 2009 |
4,130 |
| 4 |
Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C
Yasuhito Tanaka et al. · Nature Genetics
|
13 Sep 2009 |
2,144 |
| 5 |
ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks
Sandeep Burma, Benjamin P. Chen, Michael B. Murphy et al. · Journal of Biological Chemistry
Open access |
Nov 2001 |
1,985 |
| 6 |
Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase
Yasuhisa Kono · Archives of Biochemistry and Biophysics
|
Feb 1978 |
1,805 |
| 7 |
Universal definition and classification of heart failure: a report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure
Biykem Bozkurt et al. · European Journal of Heart Failure
Open access |
19 Feb 2021 |
1,644 |
| 8 |
Proton conduction in sintered oxides and its application to steam electrolysis for hydrogen production
Hiroyasu IWAHARA, Takao Esaka, Hiroyuki Uchida et al. · Solid State Ionics
|
Aug 1981 |
1,492 |
| 9 |
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
Wataru Satake et al. · Nature Genetics
|
15 Nov 2009 |
1,351 |
| 10 |
PI3K-Akt pathway: Its functions and alterations in human cancer
Mitsuhiko Osaki, M Oshimura, Hisao Ito · APOPTOSIS
|
25 Oct 2004 |
1,266 |
| 11 |
Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1
Lucie I. Bruijn, Megan K. Houseweart, Shinsuke Kato et al. · Science
|
18 Sep 1998 |
1,239 |
| 12 |
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis
Akari Suzuki et al. · Nature Genetics
|
27 Jun 2003 |
1,172 |
| 13 |
Self-regeneration of a Pd-perovskite catalyst for automotive emissions control
Yasuo Nishihata, Jun'ichiro Mizuki, Takahiro Akao et al. · Nature
|
Jul 2002 |
1,167 |
| 14 |
In yeast, RAS proteins are controlling elements of adenylate cyclase
Takashi Toda, Isao Uno, Tatsuo Ishikawa et al. · Cell
|
1985 |
1,146 |
| 15 |
[The Rotterdam study].
Kenji Wada, Ken‐ichiro Tanaka, Kenji Nakashima · PubMed
|
Oct 2011 |
1,134 |
| 16 |
Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus
Darwyn Kobasa, Steven M. Jones, Kyoko Shinya et al. · Nature
|
17 Jan 2007 |
950 |
| 17 |
Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts
Yuji Shiba, Toshihito Gomibuchi, Tatsuichiro Seto et al. · Nature
|
Oct 2016 |
864 |
| 18 |
Efficacy of Selpercatinib in RET Fusion–Positive Non–Small-Cell Lung Cancer
Alexander Edward Dela Cruz Drilon et al. · New England Journal of Medicine
Open access |
26 Aug 2020 |
856 |
| 19 |
Polymerase chain reaction detection of 8 putative periodontal pathogens in subgingival plaque of gingivitis and advanced periodontitis lesions
A. Ashimoto, Chider Chen, I. Bakker et al. · Oral Microbiology and Immunology
|
Aug 1996 |
854 |
| 20 |
Effect of cow manure biochar on maize productivity under sandy soil condition
Kingsley Chinyere Uzoma, Mitsuhiro Inoue, Henintsoa Andry et al. · Soil Use and Management
|
15 Apr 2011 |
851 |
| 21 |
Generation of Pluripotent Stem Cells from Neonatal Mouse Testis
Mito Kanatsu‐Shinohara, Kimiko Inoue, Jiyoung Lee et al. · Cell
Open access |
Dec 2004 |
829 |
| 22 |
Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene
Stacie K. Loftus, Jill A. Morris, Eugene D. Carstea et al. · Science
|
11 Jul 1997 |
811 |
| 23 |
Clinical characteristics of clear cell carcinoma of the ovary
Toru Sugiyama, Toshiharu Kamura, Junzo Kigawa et al. · Cancer
|
Jun 2000 |
810 |
| 24 |
Proton Conduction in Sintered Oxides Based on BaCeO3
Hiroyasu IWAHARA, Hiroyuki Uchida, Kenji Ono et al. · Journal of The Electrochemical Society
Open access |
Feb 1988 |
789 |
| 25 |
Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine
Brianna B. Williams, Andrew H. Van Benschoten, Peter Cimermančič et al. · Cell Host & Microbe
Open access |
25 Sep 2014 |
771 |
| 26 |
Soil erosion modelling: A global review and statistical analysis
Pasquale Borrelli et al. · The Science of The Total Environment
Open access |
18 Mar 2021 |
748 |
| 27 |
JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure ― Digest Version ―
Hiroyuki Tsutsui et al. · Circulation Journal
Open access |
9 Sep 2019 |
716 |
| 28 |
Hippocampal LTP Is Accompanied by Enhanced F-Actin Content within the Dendritic Spine that Is Essential for Late LTP Maintenance In Vivo
Yugo Fukazawa, Yoshito Saitoh, Fumiko Ozawa et al. · Neuron
Open access |
May 2003 |
705 |
| 29 |
Integrating neuroimmune systems in the neurobiology of depression
Eric S. Wohleb, Tina Franklin, Masaaki Iwata et al. · Nature reviews. Neuroscience
Review |
9 Jun 2016 |
689 |
| 30 |
Global, regional, and country level need for data on wastewater generation, treatment, and use
Toshio Sato, Manzoor Qadir, Sadahiro Yamamoto et al. · Agricultural Water Management
|
Sep 2013 |
660 |
| 31 |
Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors
Shinya Yamada et al. · Nature
|
Nov 2006 |
639 |
| 32 |
Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria
Manisha Balwani et al. · New England Journal of Medicine
Open access |
10 Jun 2020 |
617 |
| 33 |
Biodegradation of plastics
Masayuki Shimao · Current Opinion in Biotechnology
Review |
Jun 2001 |
614 |
| 34 |
Characterization of Avian H5N1 Influenza Viruses from Poultry in Hong Kong
K. F. Shortridge, Nan Zhou, Yi Guan et al. · Virology
Open access |
Dec 1998 |
596 |
| 35 |
Nursing Competency: Definition, Structure and Development
Mika Fukada · Yonago acta medica
Open access |
2018 |
581 |
| 36 |
Role of cytokines in endometriosis
Tasuku Harada, Tomio Iwabe, Naoki Terakawa · Fertility and Sterility
Open access |
Jul 2001 |
579 |
| 37 |
Environmental factors of cancer of the colon and rectum
Ernest L. Wynder, Takao Shigematsu · Cancer
|
Sep 1967 |
565 |
| 38 |
The varicella zoster virus vasculopathies
Maria A. Nagel et al. · Neurology
Open access |
10 Mar 2008 |
545 |
| 39 |
d -β-Hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease
Yoshihiro Kashiwaya, Takao Takeshima, Nozomi Mori et al. · Proceedings of the National Academy of Sciences
Open access |
9 May 2000 |
544 |
| 40 |
Expression of P-glycoprotein in Human Placenta: Relation to Genetic Polymorphism of the Multidrug Resistance (MDR)-1 Gene
Mizuho Tanabe, Ichiro Ieiri, Naoki Nagata et al. · Journal of Pharmacology and Experimental Therapeutics
|
Jun 2001 |
534 |
| 41 |
Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1
Hiroyasu Nakano, Masahisa Shindo, Sachiko Komazawa‐Sakon et al. · Proceedings of the National Academy of Sciences
Open access |
31 Mar 1998 |
523 |
| 42 |
Vitamin B 12 Sources and Bioavailability
Fumio Watanabe · Experimental Biology and Medicine
|
Nov 2007 |
521 |
| 43 |
Sialic Acid Species as a Determinant of the Host Range of Influenza A Viruses
Yasuo Suzuki, Toshihiro Ito, Takashi Suzuki et al. · Journal of Virology
Open access |
15 Dec 2000 |
517 |
| 44 |
Comprehensive assessment of soil erosion risk for better land use planning in river basins: Case study of the Upper Blue Nile River
Nigussie Haregeweyn, Atsushi Tsunekawa, Jean Poesen et al. · The Science of The Total Environment
Open access |
12 Sep 2016 |
515 |
| 45 |
What is Social Capital? A Comprehensive Review of the Concept
Humnath Bhandari, Kumi Yasunobu · Asian journal of social science
|
2009 |
515 |
| 46 |
Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics
Yohei Nishizato · Clinical Pharmacology & Therapeutics
|
Jun 2003 |
513 |
| 47 |
Application of silicon enhanced drought tolerance in Sorghum bicolor
Taiichiro Hattori, Shinobu Inanaga, Hideki Araki et al. · Physiologia Plantarum
|
23 Mar 2005 |
512 |
| 48 |
Preparation of Chitin Nanofibers with a Uniform Width as α-Chitin from Crab Shells
Shinsuke Ifuku, Masaya Nogi, Kentaro Abe et al. · Biomacromolecules
|
27 Apr 2009 |
501 |
| 49 |
Chitin nanofibers: preparations, modifications, and applications
Shinsuke Ifuku, Hiroyuki Saimoto · Nanoscale
Open access |
2012 |
488 |
| 50 |
Dicer is essential for formation of the heterochromatin structure in vertebrate cells
Tatsuo Fukagawa, Masahiro Nogami, Mitsuko Yoshikawa et al. · Nature Cell Biology
|
11 Jul 2004 |
487 |