Institution · UCB Pharma (United Kingdom)

Most cited papers from UCB Pharma (United Kingdom)

UCB Pharma (United Kingdom)

What are the most cited papers from UCB Pharma (United Kingdom)?

The most cited paper from UCB Pharma (United Kingdom) is "Natural products in drug discovery: advances and opportunities" (Atanas G. Atanasov et al., 2021), with 5,395 citations. Next come "Rings in Drugs" (2,540) and "Organic synthesis provides opportunities to transform drug discovery" (1,554).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 59 papers. Every paper with more than 267 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Natural products in drug discovery: advances and opportunities Atanas G. Atanasov et al. · Nature Reviews Drug Discovery ReviewOpen access	28 Jan 2021	5,395
2	Rings in Drugs Richard D. Taylor, Malcolm MacCoss, Alastair D. G. Lawson · Journal of Medicinal Chemistry	28 Jan 2014	2,540
3	Organic synthesis provides opportunities to transform drug discovery David C. Blakemore, Luis C. Misal Castro, Ian Churcher et al. · Nature Chemistry	22 Mar 2018	1,554
4	Certolizumab Pegol for the Treatment of Crohn's Disease William J. Sandborn, Brian G. Feagan, Simeon Stoinov et al. · New England Journal of Medicine Open access	18 Jul 2007	1,146
5	Maintenance Therapy with Certolizumab Pegol for Crohn's Disease Stefan Schreiber, Mani Khaliq-Kareemi, Ian Craig Lawrance et al. · New England Journal of Medicine	18 Jul 2007	1,050
6	Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis Xinyang Song, Ximei Sun, Sungwhan F. Oh et al. · Nature Open access	25 Dec 2019	1,031
7	Individual intestinal symbionts induce a distinct population of RORγ + regulatory T cells Esen Sefik, Naama Geva‐Zatorsky, Sungwhan F. Oh et al. · Science Open access	13 Aug 2015	903
8	Biochemical Characterization of Human Collagenase-3 Vera Knäuper, Carlos López-Otı́n, Bryan Ronain Smith et al. · Journal of Biological Chemistry Open access	1996	887
9	Mining the Human Gut Microbiota for Immunomodulatory Organisms Naama Geva‐Zatorsky, Esen Sefik, Lindsay H. Kua et al. · Cell Open access	Feb 2017	814
10	Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments Glenn Robert Masson et al. · Nature Methods Open access	27 Jun 2019	804
11	SAbDab: the structural antibody database James B. Dunbar, Konrad Krawczyk, Jinwoo Leem et al. · Nucleic Acids Research Open access	8 Nov 2013	763
12	Cellular Mechanisms for Human Procollagenase-3 (MMP-13) Activation Vera Knäuper, Horst Günter Will, Carlos López-Otı́n et al. · Journal of Biological Chemistry Open access	Jul 1996	754
13	A novel coumarin‐labelled peptide for sensitive continuous assays of the matrix metalloproteinases Christopher G. Knight, Frances W. Willenbrock, Gillian Murphy · FEBS Letters	27 Jan 1992	708
14	Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity Andrew Docherty, Alan Lyons, Bryan John Smith et al. · Nature	Nov 1985	696
15	Single‐Particle Tracking and Modulation of Cell Entry Pathways of a Tetrahedral DNA Nanostructure in Live Cells Le Liang, Jiang Li, Qian Li et al. · Angewandte Chemie International Edition	14 May 2014	584
16	The phage abortive infection system, ToxIN, functions as a protein–RNA toxin–antitoxin pair Peter C. Fineran, Tim R. Blower, Ian J. Foulds et al. · Proceedings of the National Academy of Sciences Open access	5 Jan 2009	581
17	A Randomized, Placebo-Controlled Trial of Certolizumab Pegol (CDP870) for Treatment of Crohn’s Disease Stefan Schreiber, Paul J. Rutgeerts, Richard Neil Fedorak et al. · Gastroenterology	Sep 2005	581
18	Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: Findings of a fifty‐two–week, phase III, multicenter, randomized, double‐blind, placebo‐controlled, parallel‐group study Edward Clark Keystone, Désirée M F M van der Heijde, David H. Mason et al. · Arthritis & Rheumatism	30 Oct 2008	578
19	The Soluble Catalytic Domain of Membrane Type 1 Matrix Metalloproteinase Cleaves the Propeptide of Progelatinase A and Initiates Autoproteolytic Activation Horst Günter Will, Susan J. Atkinson, Georgina S. Butler et al. · Journal of Biological Chemistry Open access	Jul 1996	571
20	PEGylated antibodies and antibody fragments for improved therapy: a review Andrew P. Chapman · Advanced Drug Delivery Reviews Review	Jun 2002	561
21	Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer Khaled M. Ali, Dalya R. Soond, Roberto Piñeiro et al. · Nature Open access	11 Jun 2014	553
22	Arpeggio: A Web Server for Calculating and Visualising Interatomic Interactions in Protein Structures Harry C. Jubb, Alícia P. Higueruelo, Bernardo Ochoa‐Montaño et al. · Journal of Molecular Biology Open access	10 Dec 2016	543
23	A Randomized Controlled Trial of Acetyl Salicyclic Acid in the Secondary Prevention of Mortality from Myocardial Infarction P C Elwood, Alexandra Cochrane, M L Burr et al. · BMJ Open access	9 Mar 1974	521
24	Hybridization Chain Reaction Amplification of MicroRNA Detection with a Tetrahedral DNA Nanostructure-Based Electrochemical Biosensor Zhilei Ge, Meihua Lin, Ping Wang et al. · Analytical Chemistry	22 Jan 2014	502
25	Glucocorticoids promote breast cancer metastasis Milan M. S. Obradović, Baptiste Hamelin, Nenad Manevski et al. · Nature Open access	Mar 2019	484
26	Mechanism of action of certolizumab pegol (CDP870): In vitro comparison with other anti-tumor necrosis factor α agents Andrew M. Nesbitt, Gianluca Fossati, Marianne Bergin et al. · Inflammatory Bowel Diseases	16 Jul 2007	477
27	Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP) Gillian Murphy, Mark I. Cockett, Robin V. Ward et al. · Biochemical Journal Open access	Jul 1991	456
28	Programmable Engineering of a Biosensing Interface with Tetrahedral DNA Nanostructures for Ultrasensitive DNA Detection Meihua Lin, Jingjing Wang, Guobao Zhou et al. · Angewandte Chemie International Edition	29 Dec 2014	450
29	Smart Drug Delivery Nanocarriers with Self‐Assembled DNA Nanostructures Jiang Li, Chunhai Fan, Hao Pei et al. · Advanced Materials	13 Jun 2013	443
30	Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice Tze Guan Tan, Esen Sefik, Naama Geva‐Zatorsky et al. · Proceedings of the National Academy of Sciences Open access	23 Nov 2016	432
31	Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength Michael S. Ominsky et al. · Journal of Bone and Mineral Research Open access	Feb 2010	415
32	Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines Revital Shamri, Valentin Grabovsky, Jean-Marc Gauguet et al. · Nature Immunology	17 Apr 2005	411
33	Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study Xavier Mariette, Frauke Förger, Bincy P Abraham et al. · Annals of the Rheumatic Diseases Open access	30 Oct 2017	401
34	Electrochemical detection of nucleic acids, proteins, small molecules and cells using a DNA-nanostructure-based universal biosensing platform Meihua Lin, Ping Song, Guobao Zhou et al. · Nature Protocols	16 Jun 2016	393
35	An Exonuclease III‐Powered, On‐Particle Stochastic DNA Walker Xiangmeng Qu, Dan Zhu, Guangbao Yao et al. · Angewandte Chemie International Edition	12 Jan 2017	391
36	Five computational developability guidelines for therapeutic antibody profiling Matthew I. J. Raybould, Claire Marks, Konrad Krawczyk et al. · Proceedings of the National Academy of Sciences Open access	14 Feb 2019	387
37	Blood monocytes: distinct subsets, how they relate to dendritic cells, and their possible roles in the regulation of T‐cell responses Frédéric Geissmann, Cédric Auffray, Roger T. Palframan et al. · Immunology and Cell Biology	8 Apr 2008	383
38	Methods for converting cysteine to dehydroalanine on peptides and proteins Justin M. Chalker, Smita B. Gunnoo, Omar Boutureira et al. · Chemical Science	2011	373
39	The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity Rune Busk Damgaard, Jennifer A. Walker, Paola Marco‐Casanova et al. · Cell Open access	Aug 2016	364
40	Antibody-targeted chemotherapy with CMC-544: a CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignancies John F. DiJoseph, Douglas C. Armellino, Erwin R. Boghaert et al. · Blood Open access	18 Nov 2003	362
41	Strategies for the Assessment of Protein Aggregates in Pharmaceutical Biotech Product Development John den Engelsman, Patrick Garidel, Ronald A. Smulders et al. · Pharmaceutical Research Open access	22 Oct 2010	354
42	Whole-exome sequencing in undiagnosed genetic diseases: interpreting 119 trios Xiaolin Zhu et al. · Genetics in Medicine Open access	15 Jan 2015	354
43	The Role of the C-terminal Domain of Human Collagenase-3 (MMP-13) in the Activation of Procollagenase-3, Substrate Specificity, and Tissue Inhibitor of Metalloproteinase Interaction Vera Knäuper, Susan Cowell, Bryan Ronain Smith et al. · Journal of Biological Chemistry Open access	Mar 1997	351
44	In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576. Prakash Mistry, Alistair J. Stewart, Wendy Dangerfield et al. · PubMed	15 Jan 2001	350
45	Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss Akilan Krishnamurthy et al. · Annals of the Rheumatic Diseases Open access	26 Nov 2015	349
46	Therapeutic antibody fragments with prolonged in vivo half-lives Andrew P. Chapman, Pari Antoniw, Mariangela Spitali et al. · Nature Biotechnology	Aug 1999	349
47	Structure and Interactions of the Human Programmed Cell Death 1 Receptor Xiaoxiao Cheng, Václav Veverka, Anand Radhakrishnan et al. · Journal of Biological Chemistry Open access	16 Feb 2013	337
48	A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density Nicholas M. Pearce, Tobias J. Krojer, Anthony R Bradley et al. · Nature Communications Open access	24 Apr 2017	334
49	Efficient synthesis of enzymatically active calf chymosin in Saccharomyces cerevisiae Jane Mellor, Melanie J. Dobson, Nigel A. Roberts et al. · Gene	Sep 1983	333
50	Codon usage can affect efficiency of translation of genes inEscherichia coli M K Robinson, R.J. Lilley, Stephen F. Little et al. · Nucleic Acids Research Open access	1984	296

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.