Science Explorer Back to mapMap
Institution · UPMC Health System

Most cited papers from UPMC Health System

What are the most cited papers from UPMC Health System?

The most cited paper from UPMC Health System is "The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)" (Mervyn Singer, Clifford Scott Deutschman, Christopher W. Seymour et al., 2016), with 29,012 citations. Next come "Mechanisms of Bone Metastasis" (2,764) and "Asthma phenotypes: the evolution from clinical to molecular approaches" (2,446).

Showing 50 of 59 papers. Every paper with more than 541 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) Mervyn Singer, Clifford Scott Deutschman, Christopher W. Seymour et al. · JAMA Open access 22 Feb 2016 29,012
2 Mechanisms of Bone Metastasis Garson David Roodman · New England Journal of Medicine 14 Apr 2004 2,764
3 Asthma phenotypes: the evolution from clinical to molecular approaches Sally E. Wenzel · Nature Medicine May 2012 2,446
4 Historical (1850–2000) gridded anthropogenic and biomass burning emissions of reactive gases and aerosols: methodology and application Jean‐François Lamarque et al. · Atmospheric chemistry and physics Open access 3 Aug 2010 2,430
5 STROCSS 2021: Strengthening the reporting of cohort, cross-sectional and case-control studies in surgery Ginimol Mathew et al. · International Journal of Surgery Open access 10 Nov 2021 2,166
6 Clinical Guideline for the Evaluation and Management of Chronic Insomnia in Adults Sharon Schutte-Rodin, Lauren Broch, Daniel J. Buysse et al. · Journal of Clinical Sleep Medicine Open access 15 Oct 2008 1,957
7 Accurately extracting the signature of intermolecular interactions present in the NCI plot of the reduced density gradient versus electron density Corentin Lefebvre, Gaëtan Rubez, Hassan K. Khartabil et al. · Physical Chemistry Chemical Physics 2017 1,843
8 Polyvinylpyrrolidone (PVP) in nanoparticle synthesis Kallum M. Koczkur, Stefanos Mourdikoudis, Lakshminarayana Polavarapu et al. · Dalton Transactions Open access 2015 1,790
9 Cellular and molecular mechanisms of renal fibrosis Youhua Liu · Nature Reviews Nephrology ReviewOpen access 18 Oct 2011 1,464
10 Development and Validation of the Voice Handicap Index‐10 Clark A. Rosen, Annie Seong Lee, Jamie C. Osborne et al. · The Laryngoscope 26 Aug 2004 1,403
11 A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder Mary Louise Phillips, Cecile D. Ladouceur, Wayne Curtis Drevets · Molecular Psychiatry Open access 24 Jun 2008 1,397
12 Development of Short Forms From the PROMIS™ Sleep Disturbance and Sleep-Related Impairment Item Banks Lan Yu, Daniel J. Buysse, Anne Germain et al. · Behavioral Sleep Medicine Open access 2012 1,308
13 Environmental Contamination Due to Methicillin-Resistant Staphylococcus aureus: Possible Infection Control Implications John M. Boyce, Gail Potter-Bynoe, Claire Chenevert et al. · Infection Control and Hospital Epidemiology Sep 1997 1,289
14 Suicidality and Depression Disparities Between Sexual Minority and Heterosexual Youth: A Meta-Analytic Review Michael P. Marshal, Laura J. Dietz, Mark Friedman et al. · Journal of Adolescent Health Open access 8 Jun 2011 1,221
15 Global data set of biogenic VOC emissions calculated by the MEGAN model over the last 30 years K. Sindelarova, Claire Granier, Idir Bouarar et al. · Atmospheric chemistry and physics Open access 9 Sep 2014 1,208
16 Monitoring of atmospheric composition using the thermal infrared IASI/MetOp sounder C. Clerbaux, A. Boynard, Lieven Clarisse et al. · Atmospheric chemistry and physics Open access 20 Aug 2009 1,031
17 Molecular genetics and diagnosis of thyroid cancer Yuri E. Nikiforov, Marina N. Nikiforova · Nature Reviews Endocrinology Review 30 Aug 2011 1,023
18 Sexual orientation and adolescent substance use: a meta‐analysis and methodological review* Michael P. Marshal, Mark Friedman, Ron D. Stall et al. · Addiction Open access 13 Mar 2008 1,011
19 Atmospheric composition change – global and regional air quality P. S. Monks et al. · Atmospheric Environment Open access 29 Aug 2009 974
20 HMGB1 in health and disease Rui Kang, Ruochan Chen, Qiuhong Zhang et al. · Molecular Aspects of Medicine Open access 8 Jul 2014 973
21 PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals Sally E. Wenzel et al. · Cell Open access Oct 2017 962
22 Relapse prevention with antidepressant drug treatment in depressive disorders: a systematic review John Geddes, Stuart M Carney, Christina Davies et al. · The Lancet Review Feb 2003 952
23 Right ventricular failure in patients with the HeartMate II continuous-flow left ventricular assist device: Incidence, risk factors, and effect on outcomes Robert L. Kormos, Jeffrey J. Teuteberg, Francis D. Pagani et al. · Journal of Thoracic and Cardiovascular Surgery Open access 5 Feb 2010 942
24 Dementia and Cognitive Impairment Julie Hugo, Mary Ganguli · Clinics in Geriatric Medicine Open access 12 Jun 2014 927
25 Demographic, physical and mental health assessments in the adolescent brain and cognitive development study: Rationale and description Deanna M. Barch, Matthew D. Albaugh, Shelli Avenevoli et al. · Developmental Cognitive Neuroscience Open access 3 Nov 2017 904
26 Major depressive disorder: new clinical, neurobiological, and treatment perspectives David J. Kupfer, Ellen F. Frank, Mary Louise Phillips · The Lancet Open access 19 Dec 2011 898
27 Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19 Derek C. Angus et al. · JAMA Open access 2 Sep 2020 895
28 Social Media Use and Perceived Social Isolation Among Young Adults in the U.S. Brian A. Primack, Ariel S. Shensa, Jaime E. Sidani et al. · American Journal of Preventive Medicine Open access 6 Mar 2017 881
29 New Insights into Epithelial-Mesenchymal Transition in Kidney Fibrosis Youhua Liu · Journal of the American Society of Nephrology Open access 18 Dec 2009 875
30 Sleep: A Health Imperative Faith S. Luyster, Patrick J. Strollo, Phyllis C. Zee et al. · SLEEP Open access 31 May 2012 874
31 A Randomized Study of Endobronchial Valves for Advanced Emphysema Frank C. Sciurba, Armin Ernst, Felix J.F. Herth et al. · New England Journal of Medicine Open access 22 Sep 2010 855
32 Adjust for Multiple Comparisons? It’s Not That Simple Andrew D. Althouse · The Annals of Thoracic Surgery Open access 25 Apr 2016 848
33 The changing therapeutic landscape of head and neck cancer John D. Cramer, Barbara Ann Burtness, Quynh‐Thu Le et al. · Nature Reviews Clinical Oncology Review 12 Jun 2019 833
34 The nuisance of nuisance regression: Spectral misspecification in a common approach to resting-state fMRI preprocessing reintroduces noise and obscures functional connectivity Michael N. Hallquist, Kai Hwang, Beatríz Luna · NeuroImage Open access 6 Jun 2013 828
35 Lewy Bodies in Alzheimer's Disease: A Neuropathological Review of 145 Cases Using α‐Synuclein Immunohistochemistry Ronald L. Hamilton · Brain Pathology Open access Jul 2000 768
36 AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity Xinxin Song, Shan Zhu, Pan Chen et al. · Current Biology Open access 26 Jul 2018 764
37 The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC) Ezra E.W. Cohen, R. Bryan Bell, Carlo Bruno Bifulco et al. · Journal for ImmunoTherapy of Cancer Open access 15 Jul 2019 756
38 Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: Review and meta‐analysis Camille C. Rose Ragin, Emanuela Taioli · International Journal of Cancer Jun 2007 754
39 Rhythms of life: circadian disruption and brain disorders across the lifespan Ryan W. Logan, Colleen A. McClung · Nature reviews. Neuroscience ReviewOpen access 20 Nov 2018 729
40 Cognitive Deficits in Unaffected First-Degree Relatives of Schizophrenia Patients: A Meta-analytic Review of Putative Endophenotypes Beth Ellen Snitz · Schizophrenia Bulletin Open access 15 Sep 2005 716
41 Partial recovery of visual function in a blind patient after optogenetic therapy José‐Alain Sahel, Élise Boulanger-Scemama, Chloé Pagot et al. · Nature Medicine 24 May 2021 713
42 A Review of Antimicrobial Peptides and Their Therapeutic Potential as Anti-Infective Drugs Y. Jerold Gordon, Eric G. Romanowski, Alison M. McDermott · Current Eye Research Open access 2005 703
43 Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force Josef S Smolen et al. · Annals of the Rheumatic Diseases Open access 7 Jul 2017 688
44 Recommendations for Planning Pilot Studies in Clinical and Translational Research Charity Galena Moore, Rickey E. Carter, Paul J. Nietert et al. · Clinical and Translational Science Open access Oct 2011 683
45 Bipolar disorder diagnosis: challenges and future directions Mary Louise Phillips, David J. Kupfer · The Lancet Open access May 2013 678
46 Rare coding variation provides insight into the genetic architecture and phenotypic context of autism Jack M. Fu et al. · Nature Genetics Open access117 authors 18 Aug 2022 665
47 Clinical Course of Children and Adolescents With Bipolar Spectrum Disorders Boris B. Birmaher, David Axelson, Michael A. Strober et al. · Archives of General Psychiatry Open access Feb 2006 657
48 Circadian rhythm disturbances in depression Anne Germain, David J. Kupfer · Human Psychopharmacology Clinical and Experimental Open access 5 Aug 2008 651
49 The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis Meihong Deng et al. · Immunity Open access Oct 2018 623
50 Single photon-emission computed tomography Thomas A. Holly, Brian Abbott, Mouaz Husayn Al-Mallah et al. · Journal of Nuclear Cardiology 14 Jun 2010 599

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.