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Most cited papers from Vaccine Research Center

What are the most cited papers from Vaccine Research Center?

The most cited paper from Vaccine Research Center is "Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation" (Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett et al., 2020), with 9,833 citations. Next come "Microbial translocation is a cause of systemic immune activation in chronic HIV infection" (3,596) and "An mRNA Vaccine against SARS-CoV-2 — Preliminary Report" (3,519).

Showing 50 of 59 papers. Every paper with more than 687 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett et al. · Science Open access 19 Feb 2020 9,833
2 Microbial translocation is a cause of systemic immune activation in chronic HIV infection Jason M. Brenchley, David Anthony Price, Timothy W. Schacker et al. · Nature Medicine 19 Nov 2006 3,596
3 An mRNA Vaccine against SARS-CoV-2 — Preliminary Report Lisa A. Jackson et al. · New England Journal of Medicine Open access 14 Jul 2020 3,519
4 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors 2 Jan 2021 2,743
5 Antibody neutralization and escape by HIV-1 Xiping Wei, Julie M. Decker, Shuyi Wang et al. · Nature 19 Mar 2003 2,480
6 A human memory T cell subset with stem cell–like properties Luca Gattinoni, Enrico Lugli, Yun Ji et al. · Nature Medicine Open access 18 Sep 2011 2,012
7 Vaccine Adjuvants: Putting Innate Immunity to Work Robert L. Coffman, Alan Sher, Robert A. Seder · Immunity Open access Oct 2010 1,961
8 Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial Barton F. Haynes et al. · New England Journal of Medicine Open access 4 Apr 2012 1,851
9 HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells Michael R. Betts · Blood Open access 7 Feb 2006 1,843
10 CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract Jason M. Brenchley, Timothy W. Schacker, Laura E. Ruff et al. · The Journal of Experimental Medicine Open access 13 Sep 2004 1,843
11 Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1 Xueling Wu et al. · Science Open access 8 Jul 2010 1,817
12 HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation Nicolas Chomont, Mohamed El‐Far, Petronela Ancuța et al. · Nature Medicine Open access 21 Jun 2009 1,769
13 SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness Kizzmekia S. Corbett et al. · Nature Open access 5 Aug 2020 1,695
14 Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike Lihong Liu et al. · Nature Open access 22 Jul 2020 1,622
15 Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation Michael R. Betts, Jason M. Brenchley, David Anthony Price et al. · Journal of Immunological Methods 12 Sep 2003 1,600
16 T-cell quality in memory and protection: implications for vaccine design Robert A. Seder, Patricia A. Darrah, Mario Roederer · Nature reviews. Immunology Review 7 Mar 2008 1,589
17 Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major Patricia A. Darrah, Dipti T. Patel, Paula Mello De Luca et al. · Nature Medicine 10 Jun 2007 1,415
18 Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection Joseph J. Mattapallil, Daniel C. Douek, Brenna J. Hill et al. · Nature 27 Mar 2005 1,289
19 HIV preferentially infects HIV-specific CD4+ T cells Daniel C. Douek, Jason M. Brenchley, Michael R. Betts et al. · Nature May 2002 1,278
20 Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen Jesper Pallesen, Nianshuang Wang, Kizzmekia S. Corbett et al. · Proceedings of the National Academy of Sciences Open access 14 Aug 2017 1,241
21 Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial Peter B. Gilbert et al. · Science Open access 6 Jan 2022 1,218
22 Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01 Tongqing Zhou, Ivelin S. Georgiev, Xueling Wu et al. · Science Open access 8 Jul 2010 1,187
23 Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus Jason S. McLellan et al. · Science Open access 31 Oct 2013 1,172
24 Antiretroviral-Drug Resistance among Patients Recently Infected with HIV Susan J. Little, Sarah Holte, Jean‐Pierre Routy et al. · New England Journal of Medicine Open access 8 Aug 2002 1,148
25 Human Immunodeficiency Virus Type 1 env Clones from Acute and Early Subtype B Infections for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies Ming Li, Feng Gao, John R. Mascola et al. · Journal of Virology Open access 28 Jul 2005 1,096
26 Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells Jason M. Brenchley, Nitin J. Karandikar, Michael R. Betts et al. · Blood 17 Mar 2003 1,079
27 Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus Hua‐Xin Liao et al. · Nature Open access 2 Apr 2013 1,066
28 Seventeen-colour flow cytometry: unravelling the immune system Stephen P. Perfetto, Pratip K. Chattopadhyay, Mario Roederer · Nature reviews. Immunology Review 30 Jul 2004 1,036
29 SARS-CoV-2 infection and persistence in the human body and brain at autopsy Sydney R. Stein et al. · Nature Open access100 authors 14 Dec 2022 928
30 Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies Masaru Kanekiyo, Chih‐Jen Wei, Hadi Mohamad Yassine et al. · Nature Open access 21 May 2013 923
31 HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Peter D. Kwong et al. · Nature Dec 2002 907
32 Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination Norbert Pardi et al. · Nature Open access 2 Feb 2017 903
33 Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo Anne W. Rimoin, Prime M. Mulembakani, Sara C. Johnston et al. · Proceedings of the National Academy of Sciences Open access 30 Aug 2010 903
34 Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody Jason S. McLellan, Man Chen, Sherman S. Leung et al. · Science Open access 26 Apr 2013 903
35 Similarities and differences in CD4+ and CD8+ effector and memory T cell generation Robert A. Seder, Rafi Ahmed · Nature Immunology 26 Aug 2003 900
36 Systemic Effects of Inflammation on Health during Chronic HIV Infection Steven G. Deeks, Russell P. Tracy, Daniel C. Douek · Immunity Open access Oct 2013 897
37 PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection Constantinos Petrovas, Joseph Paul Casazza, Jason M. Brenchley et al. · The Journal of Experimental Medicine Open access 5 Sep 2006 887
38 Animal models for COVID-19 César Muñoz‐Fontela et al. · Nature Open access 23 Sep 2020 884
39 SPICE: Exploration and analysis of post‐cytometric complex multivariate datasets Mario Roederer, Joshua L. Nozzi, Martha Nason · Cytometry Part A Open access 7 Jan 2011 871
40 Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 Jason S. McLellan et al. · Nature Open access 22 Nov 2011 859
41 Broad and potent neutralization of HIV-1 by a gp41-specific human antibody Jinghe Huang, Gilad Ofek, Leo Laub et al. · Nature Open access 18 Sep 2012 859
42 Endosomal Proteolysis of the Ebola Virus Glycoprotein Is Necessary for Infection Kartik Chandran, Nancy J. Sullivan, Ute Felbor et al. · Science Open access 14 Apr 2005 846
43 The who's who of T ‐cell differentiation: Human memory T ‐cell subsets Yolanda D. Mahnke, Tess Melinda Brodie, Federica Sallusto et al. · European Journal of Immunology Open access 30 Oct 2013 839
44 Rapid COVID-19 vaccine development Barney S. Graham · Science 8 May 2020 836
45 Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing Xueling Wu et al. · Science Open access 12 Aug 2011 825
46 Structure and immune recognition of trimeric pre-fusion HIV-1 Env Marie Pancera et al. · Nature Open access Oct 2014 794
47 Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine Robert A. Seder et al. · Science 101 authors 9 Aug 2013 785
48 Distribution and three-dimensional structure of AIDS virus envelope spikes Ping Zhu, Jun Liu, Julian W. Bess et al. · Nature 24 May 2006 776
49 Structural definition of a conserved neutralization epitope on HIV-1 gp120 Tongqing Zhou, Ling Xu, Barna Dey et al. · Nature Open access 14 Feb 2007 775
50 HIV vaccine design and the neutralizing antibody problem Dennis R. Burton, Ronald C. Desrosiers, Robert W. Doms et al. · Nature Immunology 25 Feb 2004 769

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.