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Most cited papers from Vaccinex (United States)

What are the most cited papers from Vaccinex (United States)?

The most cited paper from Vaccinex (United States) is "Runx2-mediated regulation of the zinc finger Osterix/Sp7 gene" (Yasuhiko Nishio, Yufeng Dong, Mark J. Paris et al., 2006), with 346 citations. Next come "A biological classification of Huntington's disease: the Integrated Staging System" (336) and "CXCL13 antibody for the treatment of autoimmune disorders" (127).

Showing 50 of 89 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Runx2-mediated regulation of the zinc finger Osterix/Sp7 gene Yasuhiko Nishio, Yufeng Dong, Mark J. Paris et al. · Gene 30 Mar 2006 346
2 A biological classification of Huntington's disease: the Integrated Staging System Sarah J. Tabrizi, Scott Schobel, Emily C. Gantman et al. · The Lancet Neurology 15 Jun 2022 336
3 CXCL13 antibody for the treatment of autoimmune disorders Ekaterina Klimatcheva, Tracy Pandina, Christine A. Reilly et al. · BMC Immunology Open access 10 Feb 2015 127
4 SEMA4D compromises blood–brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease Ernest Smith et al. · Neurobiology of Disease Open access 18 Oct 2014 121
5 CXCL13 is elevated in Sjögren's syndrome in mice and humans and is implicated in disease pathogenesis Jill M. Kramer, Ekaterina Klimatcheva, Thomas L. Rothstein · Journal of Leukocyte Biology Open access Aug 2013 120
6 A High-Affinity Fully Human Anti–IL-6 mAb, 1339, for the Treatment of Multiple Myeloma Mariateresa Fulciniti, Teru Hideshima, Claudine Vermot‐Desroches et al. · Clinical Cancer Research Open access 25 Nov 2009 118
7 Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease Amber L. Southwell, Sonia Franciosi, Erika B. Villanueva et al. · Neurobiology of Disease Open access 3 Feb 2015 109
8 Antibody Blockade of Semaphorin 4D Promotes Immune Infiltration into Tumor and Enhances Response to Other Immunomodulatory Therapies Elizabeth E. Evans, Alan S. Jonason, Holm Bußler et al. · Cancer Immunology Research 23 Jan 2015 108
9 Platelet factor 4 limits Th17 differentiation and cardiac allograft rejection Guanfang Shi, David James Field, Kyung-ae Ko et al. · Journal of Clinical Investigation Open access 26 Jan 2014 99
10 Cross-protective immunity following coronavirus vaccination and coronavirus infection Tanushree Dangi, Nicole Palacio, Sarah Sanchez et al. · Journal of Clinical Investigation Open access 8 Oct 2021 92
11 Immunotherapy in Triple-Negative Breast Cancer Leisha A. Emens · The Cancer Journal 2021 86
12 Antibody against Surface-Bound C5a Peptidase Is Opsonic and Initiates Macrophage Killing of Group B Streptococci Qi Cheng, Brian L. Carlson, Sub Pillai et al. · Infection and Immunity Open access Apr 2001 75
13 A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk Elad Katz, Sylvie Dubois-Marshall, Andrew H. Sims et al. · British Journal of Cancer Open access Jul 2010 75
14 Sustained activation and tumor targeting of NKT cells using a CD1d–anti-HER2–scFv fusion protein induce antitumor effects in mice Kathrin Stirnemann, Jackeline F. Romero, Lucia Baldi et al. · Journal of Clinical Investigation Open access Feb 2008 68
15 Pepinemab antibody blockade of SEMA4D in early Huntington’s disease: a randomized, placebo-controlled, phase 2 trial Andrew Feigin et al. · Nature Medicine Open access 8 Aug 2022 66
16 Safety, Pharmacokinetics, and Pharmacodynamics of a Humanized Anti-Semaphorin 4D Antibody, in a First-In-Human Study of Patients with Advanced Solid Tumors Amita Patnaik, Glen J. Weiss, John E. Leonard et al. · Clinical Cancer Research 7 Oct 2015 65
17 Semaphorin4D Inhibition Improves Response to Immune-Checkpoint Blockade via Attenuation of MDSC Recruitment and Function Paúl E. Clavijo, Jay Friedman, Yvette L. Robbins et al. · Cancer Immunology Research Open access 4 Dec 2018 62
18 Transforming Growth Factor-β and Wnt Signals Regulate Chondrocyte Differentiation through Twist1 in a Stage-Specific Manner Yu‐Feng Dong, Do Yu Soung, Yoon Soo Chang et al. · Molecular Endocrinology Open access 8 Aug 2007 60
19 C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer Elizabeth E. Evans, Alicia D. Henn, Alan S. Jonason et al. · Molecular Cancer Therapeutics Nov 2006 56
20 Generation and preclinical characterization of an antibody specific for SEMA4D Terrence Lee Fisher, Christine A. Reilly, Laurie A. Winter et al. · mAbs Open access 2 Oct 2015 55
21 Clinal patterns of desiccation and starvation resistance in ancestral and invading populations of Drosophila subobscura George W. Gilchrist, Lisa M. Jeffers, Brianna West et al. · Evolutionary Applications Open access 31 Jul 2008 54
22 Biology and significance of T‐cell apoptosis in the liver Sun Park, Debbie Murray, Beena John et al. · Immunology and Cell Biology Feb 2002 49
23 Physician Perspectives Regarding Pneumococcal Conjugate Vaccine Stanley J. Schaffer, Peter G. Szilagyi, Laura Pollard Shone et al. · PEDIATRICS Dec 2002 48
24 Anti-CXCL13 antibody can inhibit the formation of gastric lymphoid follicles induced by Helicobacter infection Koji Yamamoto, Shin Nishiumi, Lin Yang et al. · Mucosal Immunology Open access 19 Mar 2014 48
25 LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade Amber Hickman et al. · Journal of Clinical Investigation Open access 12 May 2022 44
26 Development of a Global Respiratory Severity Score (GRSS) for Respiratory Syncytial Virus Infection in Infants Mary T. Caserta, Xing Qiu, Brenda L. Tesini et al. · The Journal of Infectious Diseases Open access 16 Dec 2016 44
27 Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity Elizabeth E. Evans, Vikas A. Mishra, Crystal L. Mallow et al. · Journal of Neuroinflammation Open access 6 Aug 2022 42
28 Nonclinical Safety Evaluation of VX15/2503, a Humanized IgG4 Anti-SEMA4D Antibody John E. Leonard, Terrence Lee Fisher, Laurie A. Winter et al. · Molecular Cancer Therapeutics Open access 6 Feb 2015 36
29 Early BAFF receptor blockade mitigates murine Sjögren's syndrome: Concomitant targeting of CXCL13 and the BAFF receptor prevents salivary hypofunction Arjun Sharma, Jeremy Kiripolsky, Ekaterina Klimatcheva et al. · Clinical Immunology Open access 28 Jan 2016 35
30 CD1d-antibody fusion proteins target iNKT cells to the tumor and trigger long-term therapeutic responses Stéphanie Corgnac, Rachel Perret, Laurent Derré et al. · Cancer Immunology Immunotherapy Open access 14 Dec 2012 35
31 A Phase Ib/II Study of Pepinemab in Combination with Avelumab in Advanced Non–Small Cell Lung Cancer Michael Rahman Shafique et al. · Clinical Cancer Research 5 Apr 2021 32
32 Intranasal immunization with recombinant outer membrane protein P6 induces specific immune responses against nontypeable Haemophilus influenzae Muneki Hotomi, Noboru Yamanaka, Jun Shimada et al. · International Journal of Pediatric Otorhinolaryngology 26 Aug 2002 26
33 Saturation monitoring of VX 15/2503, a novel semaphorin 4 D ‐specific antibody, in clinical trials Terrence Lee Fisher, Jennifer Seils, Christine A. Reilly et al. · Cytometry Part B Clinical Cytometry Open access 13 Nov 2015 25
34 Polarization of Porphyromonas gingivalis–specific helper T‐cell subsets by prior immunization with Fusobacterium nucleatum Jeom‐Il Choi, Melinda A. Borrello, Smith Eh et al. · Oral Microbiology and Immunology Jun 2000 25
35 The Relationship of CD5 + B Lymphocytes to Macrophages: Insights from Normal Biphenotypic B/Macrophage Cells Melinda A. Borrello, James Palis, Richard R. Phipps · International Reviews of Immunology 2001 23
36 Antibody Library Display on a Mammalian Virus Vector: Combining the Advantages of Both Phage and Yeast Display into One Technology Ernest Smith, Maurice Zauderer · Current Drug Discovery Technologies 27 Jan 2014 20
37 Lethality-based selection of recombinant genes in mammalian cells: Application to identifying tumor antigens Ernest Smith, Aparna Mandokhot, Elizabeth E. Evans et al. · Nature Medicine Aug 2001 20
38 Construction of cDNA Libraries in Vaccinia Virus Ernest Smith, Shuying Shi, Maurice Zauderer · Humana Press eBooks Book chapter 2004 18
39 Immunomodulation of the tumor microenvironment by neutralization of Semaphorin 4D Elizabeth E. Evans, Mark J. Paris, Ernest Smith et al. · OncoImmunology Open access 29 May 2015 18
40 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two Casey R. Ager et al. · Journal for ImmunoTherapy of Cancer Open access1,802 authors Nov 2016 17
41 Enhancing the antitumor functions of invariant natural killer T cells using a soluble CD1d-CD19 fusion protein Rupali Das, Peng Guan, Susan J. Wiener et al. · Blood Advances Open access 11 Mar 2019 16
42 Photoactivable Glycolipid Antigens Generate Stable Conjugates with CD1d for Invariant Natural Killer T Cell Activation Natacha Veerapen, Shalu Sharma Kharkwal, P. J. Jervis et al. · Bioconjugate Chemistry Open access 7 Aug 2018 16
43 New Cancer Immunotherapy Agents in Development: a report from an associated program of the 31stAnnual Meeting of the Society for Immunotherapy of Cancer, 2016 Prasad S. Adusumilli et al. · Journal for ImmunoTherapy of Cancer Open access 13 Jun 2017 16
44 Anti-Semaphorin 4D Rescues Motor, Cognitive, and Respiratory Phenotypes in a Rett Syndrome Mouse Model Yilin Mao, Elizabeth E. Evans, Vikas A. Mishra et al. · International Journal of Molecular Sciences Open access 31 Aug 2021 15
45 Absolute quantitation of binding antibodies from clinical samples Chan Tang, Annemiek Verwilligen, JERALD C. SADOFF et al. · npj Vaccines Open access 6 Jan 2024 14
46 Serial Stimulation of Invariant Natural Killer T Cells with Covalently Stabilized Bispecific T-cell Engagers Generates Antitumor Immunity While Avoiding Anergy Shalu Sharma Kharkwal, Christopher T. Johndrow, Natacha Veerapen et al. · Cancer Research Open access 22 Jan 2021 14
47 The composition of immune cells serves as a predictor of adaptive immunity in a cohort of 50‐ to 74‐year‐old adults Richard B. Kennedy, Whitney L. Simon, Michael J. Gibson et al. · Immunology Open access 17 May 2016 14
48 Polymorphism of the major surface epitope of the CopB outer membrane protein ofMoraxella catarrhalis Dai-Fang Liu, Xiaoling Xie, Maria G. Mastri et al. · FEMS Immunology & Medical Microbiology Open access 16 May 2006 13
49 Characterization of immunoglobulin E responses in Balb/c mice against the major allergens of timothy grass (Phleum pratense) pollen Ulrike Seitzer, Holm Bußler, Birgit Kullmann et al. · Clinical & Experimental Allergy May 2003 11
50 Myofibroblast programming blocks differentiation of TLS-organizing fibroblastic reticular cells in pancreatic cancer Elijah Kirschstein, Olivia E. Harder, Jordan Edward Krull et al. · Cancer Cell 26 Mar 2026 10

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.