Most cited papers from Van Andel Institute

Van Andel Institute

What are the most cited papers from Van Andel Institute?

The most cited paper from Van Andel Institute is "The Immune Landscape of Cancer" (Vésteinn Thórsson et al., 2018), with 6,328 citations. Next come "Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)" (6,023) and "Parkinson disease" (5,192).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 58 papers. Every paper with more than 638 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	The Immune Landscape of Cancer Vésteinn Thórsson et al. · Immunity Open access784 authors	Apr 2018	6,328
2	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy Open access2,467 authors	2 Jan 2016	6,023
3	Parkinson disease Werner H Poewe, Klaus Seppi, Caroline M. Tanner et al. · Nature Reviews Disease Primers Review	22 Mar 2017	5,192
4	Genetic effects on gene expression across human tissues François Aguet et al. · Nature Open access250 authors	10 Oct 2017	4,762
5	The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature Open access1,384 authors	5 Feb 2020	3,854
6	Oncogenic Signaling Pathways in The Cancer Genome Atlas Francisco Sánchez-Vega et al. · Cell Open access779 authors	Apr 2018	3,452
7	Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature Open access1,324 authors	5 Feb 2020	3,360
8	Patterns of somatic mutation in human cancer genomes Christopher D. Greenman et al. · Nature Open access	Mar 2007	3,167
9	Comprehensive analyses of tumor immunity: implications for cancer immunotherapy Bo Li, Eric Allan Severson, Jean‐Christophe Pignon et al. · Genome biology Open access	22 Aug 2016	2,798
10	Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer Katherine A. Hoadley et al. · Cell Open access748 authors	Apr 2018	2,785
11	Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors	2 Jan 2021	2,743
12	Met, metastasis, motility and more Carmen Birchmeier, Walter Birchmeier, Ermanno Gherardi et al. · Nature Reviews Molecular Cell Biology Review	Dec 2003	2,620
13	Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies Mike A. Nalls et al. · The Lancet Neurology ReviewOpen access270 authors	6 Nov 2019	2,611
14	Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer A. Gordon Robertson et al. · Cell Open access213 authors	Oct 2017	2,556
15	Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation Tathiane Maistro Malta et al. · Cell Open access748 authors	Apr 2018	2,396
16	Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma Michele Ceccarelli et al. · Cell Open access208 authors	2016	2,394
17	Amyloid beta: structure, biology and structure-based therapeutic development Guo-fang Chen, Ting-Hai Xu, Yan Yan et al. · Acta Pharmacologica Sinica Open access	17 Jul 2017	2,015
18	Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer Giovanni Ciriello et al. · Cell Open access160 authors	Oct 2015	1,991
19	Integrated genomic and molecular characterization of cervical cancer Robert D. Burk et al. · Nature Open access301 authors	20 Jan 2017	1,631
20	Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21 Takeshi Inagaki, Paul A. Dutchak, Guixiang Zhao et al. · Cell Metabolism Open access	Jun 2007	1,512
21	Targeting MET in cancer: rationale and progress Ermanno Gherardi, Walter Birchmeier, Carmen Birchmeier et al. · Nature reviews. Cancer Review	24 Jan 2012	1,435
22	TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth Ken Inoki, Hongjiao Ouyang, Tianqing Zhu et al. · Cell Open access	Sep 2006	1,409
23	Epigenetic Determinants of Cancer Stephen B. Baylin, Peter Anthony Jones · Cold Spring Harbor Perspectives in Biology Open access	18 May 2016	1,398
24	The chromatin accessibility landscape of primary human cancers M. Ryan Corces et al. · Science Open access	26 Oct 2018	1,375
25	Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma Ignacio Pujol Varela et al. · Nature Open access	19 Jan 2011	1,297
26	Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics Alvaro Barbeira et al. · Nature Communications Open access264 authors	2 May 2018	1,265
27	Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas Theo Knijnenburg et al. · Cell Reports Open access763 authors	Apr 2018	1,249
28	Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes Gillian L. Dalgliesh et al. · Nature Open access	2010	1,191
29	Dynamics of Cell Generation and Turnover in the Human Heart Olaf Bergmann, Sofia Zdunek, Anastasia Felker et al. · Cell Open access	Jun 2015	1,167
30	Targeting the cancer epigenome for therapy Peter Anthony Jones, Jean‐Pierre J. Issa, Stephen B. Baylin · Nature Reviews Genetics Review	15 Sep 2016	1,166
31	The evolutionary history of 2,658 cancers Moritz Gerstung et al. · Nature Open access1,441 authors	5 Feb 2020	1,149
32	Parkinson Disease Epidemiology, Pathology, Genetics, and Pathophysiology David K. Simon, Caroline M. Tanner, Patrik Brundin · Clinics in Geriatric Medicine Open access	24 Aug 2019	1,115
33	The ADAMs family of metalloproteases: multidomain proteins with multiple functions Darren F. Seals, Sara A. Courtneidge · Genes & Development Open access	2003	1,064
34	Patterns of somatic structural variation in human cancer genomes Yilong Li et al. · Nature Open access1,411 authors	5 Feb 2020	1,005
35	Androgen receptor: structure, role in prostate cancer and drug discovery M-H. Tan, Jun Li, H. Eric Xu et al. · Acta Pharmacologica Sinica Open access	9 Jun 2014	970
36	DWARF 53 acts as a repressor of strigolactone signalling in rice Liang Jiang, Xue Liu, Guosheng Xiong et al. · Nature Open access	11 Dec 2013	914
37	Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions Brian B. Haab, Maitreya J. Dunham, Patrick O. Brown · Genome biology Open access	22 Jan 2001	892
38	Prostaglandin E 2 Promotes Colon Cancer Cell Growth Through a G s -Axin-ß-Catenin Signaling Axis Maria Domenica Castellone, Hidemi Teramoto, Bart O. Williams et al. · Science	18 Nov 2005	889
39	Sensing the environment: a historical perspective on integrin signal transduction Cindy K. Miranti, Joan S. Brugge · Nature Cell Biology	Apr 2002	870
40	Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma Michael A. Gillette et al. · Cell Open access186 authors	Jul 2020	863
41	Comprehensive characterization, annotation and innovative use of Infinium DNA methylation BeadChip probes Wanding Zhou, Peter W. Laird, Hui Shen · Nucleic Acids Research Open access	12 Oct 2016	854
42	Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Yanyong Kang et al. · Nature Open access	22 Jul 2015	845
43	The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma C. Ricketts et al. · Cell Reports Open access770 authors	Apr 2018	830
44	Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer Gijs van Haaften et al. · Nature Genetics Open access	29 Mar 2009	798
45	Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly‐available database Gilbert S. Omenn et al. · PROTEOMICS Open access	Aug 2005	796
46	Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing Isidro Cortés-Ciriano et al. · Nature Genetics Open access1,407 authors	5 Feb 2020	793
47	Intragenic ERBB2 kinase mutations in tumours Philip Stephens et al. · Nature	Sep 2004	793
48	HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome John David Carpten et al. · Nature Genetics	18 Nov 2002	755
49	A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors Karsten Melcher et al. · Nature Open access	6 Nov 2009	749
50	Signatures of mutation and selection in the cancer genome Graham R. Bignell et al. · Nature Open access	Feb 2010	735

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.