Institution · Virginia BioTechnology Research Park
Most cited papers from Virginia BioTechnology Research Park
What are the most cited papers from Virginia BioTechnology Research Park?
The most cited paper from Virginia BioTechnology Research Park is "Electroconductive hydrogels: Synthesis, characterization and biomedical applications" (Anthony Guiseppi‐Elie, 2010), with 646 citations. Next come "Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak" (514) and "Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer" (388).
Showing 50 of 59 papers. Every paper with more than 81 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Electroconductive hydrogels: Synthesis, characterization and biomedical applications Anthony Guiseppi‐Elie · Biomaterials | 9 Jan 2010 | 646 |
| 2 | Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak Michael C. Kiefer, Matthew J. Brauer, Virginia C. Powers et al. · Nature | Apr 1995 | 514 |
| 3 | Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer Zeng Qiang Yuan, Mei Sun, Richard I. Feldman et al. · Oncogene | 4 May 2000 | 388 |
| 4 | Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle Alan R. Brooks, Richard N. Harkins, Peiyin Wang et al. · The Journal of Gene Medicine | 10 Feb 2004 | 382 |
| 5 | Rational Design of a Combination Medication for the Treatment of Obesity Frank L. Greenway, M.J. Whitehouse, Maria Guttadauria et al. · Obesity | 6 Nov 2008 | 346 |
| 6 | Characterization of Pathology in Transgenic Mice Over-Expressing Human Genomic and cDNA Tau Transgenes Karen Duff, Heather Knight, Lorenzo M. Refolo et al. · Neurobiology of Disease | Apr 2000 | 314 |
| 7 | Identification of gene expression profiles that predict the aggressive behavior of breast cancer cells. Deborah A. Zajchowski, Marty F. Bartholdi, Yun Gong et al. · PubMed | Jul 2001 | 305 |
| 8 | Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow Alan R. Brooks, Peter I. Lelkes, Gabor M. Rubanyi · Physiological Genomics | 10 Apr 2002 | 294 |
| 9 | Search for characteristic structural features of mammalian mitochondrial tRNAs Mark Helm, Hervé Brulé, DAGMAR FRIEDE et al. · RNA | Oct 2000 | 290 |
| 10 | Angiotensin II is associated with activation of NF-κB-mediated genes and downregulation of PPARs Doris M. Tham, Baby Martin-McNulty, Yi-Xin Wang et al. · Physiological Genomics | 2 Oct 2002 | 278 |
| 11 | Interferon-γ Modulates a p53-independent Apoptotic Pathway and Apoptosis-related Gene Expression Natalya Ossina, Angela Cannas, Virginia C. Powers et al. · Journal of Biological Chemistry | Jun 1997 | 277 |
| 12 | Vascular estrogen receptors and endothelium-derived nitric oxide production in the mouse aorta. Gender difference and effect of estrogen receptor gene disruption. Gabor M. Rubanyi, Ana D. Freay, Katalin Zsofia Kauser et al. · Journal of Clinical Investigation | 15 May 1997 | 272 |
| 13 | Lysophospholipid Growth Factors in the Initiation, Progression, Metastases, and Management of Ovarian Cancer Xianjun Fang, Douglas C. Gaudette, Tatsuro Furui et al. · Annals of the New York Academy of Sciences | Apr 2000 | 251 |
| 14 | Apoptosis and Its Role in Human Disease Philip J. Barr, Licia Tomei · Nature Biotechnology | May 1994 | 228 |
| 15 | Thrombin Activatable Fibrinolysis Inhibitor, a Potential Regulator of Vascular Inflammation Timothy G. Myles, Toshihiko Nishimura, Thomas H. Yun et al. · Journal of Biological Chemistry | Dec 2003 | 228 |
| 16 | Furin-mediated Processing of Pro-C-type Natriuretic Peptide Chengliang Wu, Faye Y. Wu, Junliang Pan et al. · Journal of Biological Chemistry | Jul 2003 | 215 |
| 17 | The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models Ying Mei Han, Sandra Lyn Biroc, Weiwei Li et al. · Molecular Cancer Therapeutics | Sep 2006 | 180 |
| 18 | Self-report–based estimates of energy intake offer an inadequate basis for scientific conclusions Dale A. Schoeller, Diana Maria Thomas, Edward Archer et al. · American Journal of Clinical Nutrition | 20 May 2013 | 180 |
| 19 | Bioelectrical Impedance Spectroscopy for Monitoring Mammalian Cells and Tissues under Different Frequency Domains: A Review Sara Abasi, John R. Aggas, Guillermo G. Garayar-Leyva et al. · ACS Measurement Science Au | 19 Aug 2022 | 177 |
| 20 | Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells Wilfried Roth, Christine Wild‐Bode, Michael Platten et al. · Oncogene | 31 Aug 2000 | 170 |
| 21 | Effect of estrogen on endothelial function and angiogenesis Gabor M. Rubanyi, Anthony Johns, Katalin Zsofia Kauser · Vascular Pharmacology | Feb 2002 | 170 |
| 22 | The CC Chemokine I-309 Inhibits CCR8-dependent Infection by Diverse HIV-1 Strains Richard Horuk, Joseph Hesselgesser, Yiqing Zhou et al. · Journal of Biological Chemistry | 1998 | 166 |
| 23 | Processing of Pro-atrial Natriuretic Peptide by Corin in Cardiac Myocytes Faye Y. Wu, Wei Yan, Junliang Pan et al. · Journal of Biological Chemistry | May 2002 | 161 |
| 24 | Association of elevation, urbanization and ambient temperature with obesity prevalence in the United States Jameson D. Voss, Penny M. Masuoka, Bryant J. Webber et al. · International Journal of Obesity | 29 Jan 2013 | 157 |
| 25 | Implantable enzyme amperometric biosensors Christian N. Kotanen, Francis Gabriel Moussy, Sandro Carrara et al. · Biosensors and Bioelectronics | 27 Mar 2012 | 153 |
| 26 | Prevalence and Correlates of Elder Mistreatment in South Carolina: The South Carolina Elder Mistreatment Study Ananda B. Amstadter, Kristyn Zajac, Martha Kirkland Strachan et al. · Journal of Interpersonal Violence | 20 May 2011 | 152 |
| 27 | Fibroblast growth factor‐4 induces vascular permeability, angiogenesis, and arteriogenesis in a rabbit hind limb ischemia model Tuomas T. Rissanen, Johanna E. Markkanen, Katja Arve et al. · The FASEB Journal | 15 Nov 2002 | 148 |
| 28 | Cancer translocations in human cells induced by zinc finger and TALE nucleases Marion Piganeau, Hind Ghezraoui, Anne De Cian et al. · Genome Research | 8 Apr 2013 | 143 |
| 29 | Identification and Characterization of Small Molecule Functional Antagonists of the CCR1 Chemokine Receptor Joseph Hesselgesser, Howard P. Ng, Meina Liang et al. · Journal of Biological Chemistry | Jun 1998 | 138 |
| 30 | The Tumor Suppressor Maspin Does Not Undergo the Stressed to Relaxed Transition or Inhibit Trypsin-like Serine Proteases. Philip A. Pemberton, Daniel T. Wong, Helen L. Gibson et al. · Journal of Biological Chemistry | Jun 1995 | 136 |
| 31 | Thrombin-activatable fibrinolysis inhibitor (TAFI) deficiency is compatible with murine life Mariko Nagashima, Zheng-Feng Yin, Lei Zhao et al. · Journal of Clinical Investigation | 2002 | 133 |
| 32 | Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes Richard E. Straub, C J MacLean, Yunlong Ma et al. · Molecular Psychiatry | Jul 2002 | 133 |
| 33 | Real Time Analysis of the Affinity Regulation of α4-Integrin Alexandre Chigaev, Ann Marie Blenc, Julie V. Braaten et al. · Journal of Biological Chemistry | Dec 2001 | 131 |
| 34 | An Inhibitor of Activated Thrombin-Activatable Fibrinolysis Inhibitor Potentiates Tissue-Type Plasminogen Activator-Induced Thrombolysis in a Rabbit Jugular Vein Thrombolysis Model Mariko Nagashima, Matthias E. Werner, Man Ping Wang et al. · Thrombosis Research | May 2000 | 126 |
| 35 | Lipoxin and Synthetic Lipoxin Analogs: An Overview of Anti- Inflammatory Functions and New Concepts in Immunomodulation John F. Parkinson · Inflammation & Allergy - Drug Targets | Apr 2006 | 123 |
| 36 | Angiotensin II Increases Urokinase-Type Plasminogen Activator Expression and Induces Aneurysm in the Abdominal Aorta of Apolipoprotein E-Deficient Mice Yixin Wang, Baby Martin-McNulty, Ana D. Freay et al. · American Journal Of Pathology | Oct 2001 | 123 |
| 37 | Molecular Cloning and Characterization of Porphyromonas gingivalis Lysine-specific Gingipain Nadine Pavloff, Philip A. Pemberton, Jan Potempa et al. · Journal of Biological Chemistry | 1997 | 120 |
| 38 | 3D printed stimuli-responsive magnetic nanoparticle embedded alginate-methylcellulose hydrogel actuators Daria Anna Podstawczyk, Martyna Nizioł, Patrycja Szymczyk‐Ziółkowska et al. · Additive manufacturing | 28 Apr 2020 | 119 |
| 39 | Functional Analysis of the Transmembrane Domain and Activation Cleavage of Human Corin Sabine Knappe, Faye Y. Wu, Mary Rose Masikat et al. · Journal of Biological Chemistry | Dec 2003 | 116 |
| 40 | Increased aortic stiffness assessed by pulse wave velocity in apolipoprotein E-deficient mice Yixin Wang, Meredith Halks‐Miller, Ron Vergona et al. · American Journal of Physiology-Heart and Circulatory Physiology | Feb 2000 | 111 |
| 41 | Nanobiosensing with graphene and carbon quantum dots: Recent advances Brandon K. Walther, Cerasela Zoica Dinu, Dirk Michael Guldi et al. · Materials Today | 15 May 2020 | 109 |
| 42 | Viruses as an Etiology of Obesity Richard L. Atkinson · Mayo Clinic Proceedings | Oct 2007 | 105 |
| 43 | CSF 5-HIAA and aggression in female macaque monkeys: species and interindividual differences G. C. Westergaard, P. T. Mehlman, G. C. Westergaard et al. · Psychopharmacology | 21 Oct 1999 | 104 |
| 44 | Adipogenic potential of multiple human adenoviruses in vivo and in vitro in animals Leah D. Whigham, Barbara A. Israel, Richard L. Atkinson · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology | 16 Sep 2005 | 103 |
| 45 | Losing faith and finding religion: Religiosity over the life course and substance use and abuse Arden Moscati, Briana R. Mezuk · Drug and Alcohol Dependence | 6 Jan 2014 | 101 |
| 46 | Transmission of Attitudes Toward Abortion and Gay Rights: Effects of Genes, Social Learning and Mate Selection Lindon J. Eaves, Peter Hatemi · Behavior Genetics | 28 Mar 2008 | 100 |
| 47 | Bergamot Polyphenols Improve Dyslipidemia and Pathophysiological Features in a Mouse Model of Non-Alcoholic Fatty Liver Disease Vincenzo Musolino et al. · Scientific Reports | 13 Feb 2020 | 99 |
| 48 | Mechanistic Studies with Potent and Selective Inducible Nitric-oxide Synthase Dimerization Inhibitors Eric Blasko, Charles B. Glaser, James J. Devlin et al. · Journal of Biological Chemistry | 2002 | 94 |
| 49 | GLYX-13: A monoclonal antibody-derived peptide that acts as an N-methyl-d-aspartate receptor modulator Joseph R. Moskal, Amy G. Kuo, Craig Weiss et al. · Neuropharmacology | 28 Jul 2005 | 93 |
| 50 | Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa , Marc Adler, Monica J. Kochanny, Bin Ye et al. · Biochemistry | 26 Nov 2002 | 93 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.