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Most cited papers from Walther Cancer Foundation

What are the most cited papers from Walther Cancer Foundation?

The most cited paper from Walther Cancer Foundation is "NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase" (Osman Nidai Özeş, Lindsey D. Mayo, Jason A. Gustin et al., 1999), with 2,184 citations. Next come "Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase" (1,768) and "A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus" (1,226).

Showing 50 of 60 papers. Every paper with more than 233 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase Osman Nidai Özeş, Lindsey D. Mayo, Jason A. Gustin et al. · Nature Sep 1999 2,184
2 Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase Kun‐Liang Guan, Jack E. Dixon · Analytical Biochemistry Feb 1991 1,768
3 A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus Lindsey D. Mayo, David B. Donner · Proceedings of the National Academy of Sciences Open access 14 Aug 2001 1,226
4 Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist Hal E. Broxmeyer, Christie M. Orschell, D. Wade Clapp et al. · The Journal of Experimental Medicine Open access 18 Apr 2005 1,113
5 Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. Landin F. Boring, JOHN A. GOSLING, Stephen W. Chensue et al. · Journal of Clinical Investigation Open access 15 Nov 1997 1,112
6 CD44+/CD24-breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis Carol A. Sheridan, Hiromitsu Kishimoto, Robyn K. Fuchs et al. · Breast Cancer Research Open access 24 Oct 2006 994
7 Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1 Xianfeng Zhang, Jeffrey E. Settleman, John M. Kyriakis et al. · Nature Jul 1993 883
8 Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist Wayne Conrad Liles, Hal E. Broxmeyer, Elin Rodger et al. · Blood 15 Jul 2003 722
9 Phase III Trial of Gemcitabine Plus Cisplatin Versus Cisplatin Alone in Patients With Locally Advanced or Metastatic Non–Small-Cell Lung Cancer Alan B. Sandler, John J. Nemunaitis, Claude A. Denham et al. · Journal of Clinical Oncology 2000 721
10 Guideline update for MASCC and ESMO in the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting: results of the Perugia consensus conference Fausto Roila et al. · Annals of Oncology Open access May 2010 689
11 NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4 Gregory M. Helbig, Kent W. Christopherson, Poornima Bhat‐Nakshatri et al. · Journal of Biological Chemistry Open access Jun 2003 641
12 Allogeneic sibling umbilical-cord-blood transplantation in children with malignant and non-malignant disease JohnE. Wagner, Michael Steinbuch, NancyA. Kernan et al. · The Lancet Jul 1995 600
13 NF-κB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2 Hui Lin Chua, Poornima Bhat‐Nakshatri, Susan E. Clare et al. · Oncogene 24 Jul 2006 598
14 Regulation of T Cell Receptor Signaling by Tyrosine Phosphatase SYP Association with CTLA-4 Luc E. M. Marengère, Paul D. Waterhouse, Gordon S. Duncan et al. · Science 24 May 1996 570
15 Stat3 and Stat4 Direct Development of IL-17-Secreting Th Cells Anubhav N. Mathur, Hua-Chen Chang, Dimitrios G. Zisoulis et al. · The Journal of Immunology Apr 2007 559
16 Modulation of Hematopoietic Stem Cell Homing and Engraftment by CD26 Kent W. Christopherson, Giao Hangoc, Charlie Mantel et al. · Science 13 Aug 2004 512
17 High-Dose Chemotherapy and Stem-Cell Rescue for Metastatic Germ-Cell Tumors Lawrence H. Einhorn, Stephen D. Williams, Amy R. Chamness et al. · New England Journal of Medicine Open access 25 Jul 2007 498
18 Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp‐2 Tracy M. Saxton, Mark J. Henkemeyer, Stéphan Gasca et al. · The EMBO Journal Open access May 1997 481
19 The suppressive influences of human tumor necrosis factors on bone marrow hematopoietic progenitor cells from normal donors and patients with leukemia: synergism of tumor necrosis factor and interferon- gamma . Hal E. Broxmeyer, Douglas E. Williams, Li Lu et al. · The Journal of Immunology Jun 1986 480
20 Survivin, a cancer target with an emerging role in normal adult tissues Seiji Fukuda, Louis M. Pelus · Molecular Cancer Therapeutics May 2006 468
21 The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338 Alastair J. King, Huaiyu Sun, Bruce Diaz et al. · Nature 12 Nov 1998 444
22 Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2 Keyun Qing, Cathryn S. Mah, Jonathan J. Hansen et al. · Nature Medicine 1999 437
23 p53-Mediated DNA Repair Responses to UV Radiation: Studies of Mouse Cells Lacking p53, p21, and/orgadd45 Genes Martin Lloyd Smith, James M. Ford, Mary Christine Hollander et al. · Molecular and Cellular Biology Open access May 2000 425
24 The PTEN, Mdm2, p53 tumor suppressor–oncoprotein network Lindsey D. Mayo, David B. Donner · Trends in Biochemical Sciences Review Sep 2002 422
25 Identification of New Fluorescent Protein Fragments for Bimolecular Fluorescence Complementation Analysis Under Physiological Conditions Y. John Shyu, Han Liu, Xuehong Deng et al. · BioTechniques Open access 2006 411
26 In Vitro Behavior of Hematopoietic Progenitor Cells Under the Influence of Chemoattractants: Stromal Cell–Derived Factor-1, Steel Factor, and the Bone Marrow Environment Chang H. Kim, Hal E. Broxmeyer · Blood 1998 409
27 A Tyr/Ser protein phosphatase encoded by vaccinia virus Kun‐Liang Guan, Steven S. Broyles, Jack E. Dixon · Nature 28 Mar 1991 401
28 Protein-tyrosine Phosphatase Shp-2 Regulates Cell Spreading, Migration, and Focal Adhesion De-Hua Yu, Cheng‐Kui Qu, Octavian Henegariu et al. · Journal of Biological Chemistry Open access Aug 1998 386
29 Rheb Binds Tuberous Sclerosis Complex 2 (TSC2) and Promotes S6 Kinase Activation in a Rapamycin- and Farnesylation-dependent Manner Ariel Fernando Castro, John F. Rebhun, Geoffrey Clark et al. · Journal of Biological Chemistry Open access Aug 2003 386
30 A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1 Osman Nidai Özeş, Hakan Akça, Lindsey D. Mayo et al. · Proceedings of the National Academy of Sciences Open access 3 Apr 2001 384
31 Uptake of HIV-1 Tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands Ying Liu, Melina Jones, Cynthia M. Hingtgen et al. · Nature Medicine Dec 2000 383
32 A Newly Identified Member of Tumor Necrosis Factor Receptor Superfamily (TR6) Suppresses LIGHT-mediated Apoptosis Kang-Yeol Yu, Byungsuk Kwon, Byungsuk Kwon et al. · Journal of Biological Chemistry Open access May 1999 371
33 Shp-2 Tyrosine Phosphatase Functions as a Negative Regulator of the Interferon-Stimulated Jak/STAT Pathway Min You, Dehua Yu, Gen‐Sheng Feng · Molecular and Cellular Biology Open access Mar 1999 366
34 Cutting Edge: IL-17F, a Novel Cytokine Selectively Expressed in Activated T Cells and Monocytes, Regulates Angiogenesis and Endothelial Cell Cytokine Production Trevor Starnes, Michael J. Robertson, George W. Sledge et al. · The Journal of Immunology Oct 2001 359
35 PTEN Protects p53 from Mdm2 and Sensitizes Cancer Cells to Chemotherapy Lindsey D. Mayo, Jack E. Dixon, Donald L. Durden et al. · Journal of Biological Chemistry Open access Feb 2002 349
36 Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement Tim Lahm, Ivor S. Douglas, Stephen L. Archer et al. · American Journal of Respiratory and Critical Care Medicine Open access Aug 2018 346
37 Chemokines: signal lamps for trafficking of T and B cells for development and effector function Chang H. Kim, Hal E. Broxmeyer · Journal of Leukocyte Biology 1999 346
38 Cutting Edge: IL-17D, a Novel Member of the IL-17 Family, Stimulates Cytokine Production and Inhibits Hemopoiesis Trevor Starnes, Hal E. Broxmeyer, Michael J. Robertson et al. · The Journal of Immunology Open access Jul 2002 337
39 Role of 4-1BB in immune responses Dass S. Vinay, Byoung Se Kwon · Seminars in Immunology Dec 1998 312
40 Ras target proteins in eukaryotic cells Mark S. Marshall · The FASEB Journal Oct 1995 311
41 Vitamin A Metabolites Induce Gut-Homing FoxP3+ Regulatory T Cells Seung Goo Kang, Hyung Wook Lim, OURANIA M. ANDRISANI et al. · The Journal of Immunology Sep 2007 310
42 Cell wall glycosphingolipids ofSphingomonas paucimobilisare CD1d-specific ligands for NKT cells Venkataraman Sriram, Wenjun Du, Jacquelyn Gervay‐Hague et al. · European Journal of Immunology Open access 25 May 2005 309
43 Lamp-2a Facilitates MHC Class II Presentation of Cytoplasmic Antigens Delu Zhou, Ping Li, Yinling Lin et al. · Immunity Open access May 2005 305
44 Cyclooxygenase-2 expression in human pancreatic adenocarcinomas Michele T. YIP-SCHNEIDER · Carcinogenesis Feb 2000 294
45 FOXA1 Expression in Breast Cancer—Correlation with Luminal Subtype A and Survival Sunil Badve, Dmitry A. Turbin, Mangesh A. Thorat et al. · Clinical Cancer Research Aug 2007 291
46 Shp-2 Tyrosine Phosphatase: Signaling One Cell or Many Gen‐Sheng Feng · Experimental Cell Research Nov 1999 287
47 Utilization of Distinct Signaling Pathways by Receptors for Vascular Endothelial Cell Growth Factor and Other Mitogens in the Induction of Endothelial Cell Proliferation Li‐Wha Wu, Lindsey D. Mayo, James D. Dunbar et al. · Journal of Biological Chemistry Open access Feb 2000 286
48 A Reassessment of the Low Molecular Weight Phospholipase A2 Gene Family in Mammals Jay A. Tischfield · Journal of Biological Chemistry Open access Jul 1997 284
49 Selenomethionine regulation of p53 by a ref1-dependent redox mechanism Young Rok Seo, Mark R. Kelley, Martin Lloyd Smith · Proceedings of the National Academy of Sciences Open access 30 Sep 2002 282
50 A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases Lawrence A. Quilliam, John F. Rebhun, Ariel Fernando Castro · Progress in nucleic acid research and molecular biology Book chapter 2002 281

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.