| 1 |
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Christopher J L Murray et al. · The Lancet
Open access362 authors |
Dec 2012 |
9,055 |
| 2 |
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Theo Vos et al. · The Lancet
Open access358 authors |
Dec 2012 |
8,461 |
| 3 |
The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings
Ross W. Paterson et al. · Brain
Open access |
3 Jul 2020 |
1,173 |
| 4 |
The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected Tropical Diseases
Peter Jay Hotez et al. · PLoS neglected tropical diseases
Open access |
24 Jul 2014 |
1,131 |
| 5 |
Mapping the human genetic architecture of COVID-19
COVID-19 Host Genetics Initiative et al. · Nature
Open access3,896 authors |
8 Jul 2021 |
1,130 |
| 6 |
Dissemination and publication of research findings: an updated review of related biases
Fujian Song, Susan Parekh, Lee Hooper et al. · Health Technology Assessment
Open access |
Feb 2010 |
1,053 |
| 7 |
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway
Brian J. Willett et al. · Nature Microbiology
Open access692 authors |
7 Jul 2022 |
739 |
| 8 |
Quantifying the Association Between Physical Activity and Cardiovascular Disease and Diabetes: A Systematic Review and Meta‐Analysis
Ahad Wahid, Nishma Manek, Melanie S. Nichols et al. · Journal of the American Heart Association
ReviewOpen access |
Sep 2016 |
728 |
| 9 |
Langerhans cell histiocytosis (LCH): Guidelines for diagnosis, clinical work‐up, and treatment for patients till the age of 18 years
Riccardo Haupt, Milen Minkov, Itziar Astigarraga et al. · Pediatric Blood & Cancer
Open access |
25 Oct 2012 |
701 |
| 10 |
Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study
Elisabet Bergsten, AnnaCarin Horne, Maurizio Aricò et al. · Blood
Open access |
21 Sep 2017 |
682 |
| 11 |
Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19
Gavin D. Perkins et al. · JAMA
Open access408 authors |
24 Jan 2022 |
424 |
| 12 |
Effect of intravenous haloperidol on the duration of delirium and coma in critically ill patients (Hope-ICU): a randomised, double-blind, placebo-controlled trial
Valerie Joan Page, Eugene Wesley Ely, Simon Gates et al. · The Lancet Respiratory Medicine
Open access |
20 Aug 2013 |
416 |
| 13 |
Adopting and applying eco-design techniques: a practitioners perspective
Paul Knight, James O. Jenkins · Journal of Cleaner Production
Open access |
18 Nov 2008 |
407 |
| 14 |
British Association of Dermatologists’ guidelines for the management of lichen sclerosus 2010
Sallie M. Neill, Fiona Lewis, F.M. Tatnall et al. · British Journal of Dermatology
Open access |
20 Sep 2010 |
372 |
| 15 |
Nutcracker Syndrome: An Update on Current Diagnostic Criteria and Management Guidelines
Kajaluxy Ananthan, Sarah Onida, Alun Huw Davies · European Journal of Vascular and Endovascular Surgery
Open access |
27 Mar 2017 |
361 |
| 16 |
The 2020 International Alliance for the Control of Scabies Consensus Criteria for the Diagnosis of Scabies
Daniel Engelman et al. · British Journal of Dermatology
Open access |
8 Feb 2020 |
360 |
| 17 |
Whole-genome sequencing reveals host factors underlying critical COVID-19
Athanasios Kousathanas et al. · Nature
Open access2,399 authors |
7 Mar 2022 |
356 |
| 18 |
A review of the emission of VOCs from polymeric materials used in buildings
Chuck Wah Yu, Derrick Crump · Building and Environment
|
Nov 1998 |
350 |
| 19 |
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
Heather Jane Cordell et al. · Nature Communications
Open access462 authors |
22 Sep 2015 |
313 |
| 20 |
Rate of complications in scoliosis surgery – a systematic review of the Pub Med literature
Hans‐Rudolf Weiss, Deborah Goodall · Scoliosis
ReviewOpen access |
5 Aug 2008 |
267 |
| 21 |
Central Nervous System Disease in Langerhans Cell Histiocytosis
Nicole Grois, Bernhard Fahrner, Robert John Arceci et al. · The Journal of Pediatrics
Open access |
May 2010 |
261 |
| 22 |
Serum ferritin as an indicator of iron status: what do we need to know?
Jahnavi Daru, Katherine S. Colman, Simon J. Stanworth et al. · American Journal of Clinical Nutrition
Open access |
25 Oct 2017 |
248 |
| 23 |
The global burden of disease study 2013: What does it mean for the NTDs?
Jennifer R. Herricks et al. · PLoS neglected tropical diseases
Open access |
3 Aug 2017 |
241 |
| 24 |
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19
Erola Pairo‐Castineira et al. · Nature
Open access2,642 authors |
17 May 2023 |
233 |
| 25 |
Tyrian Purple: 6,6’-Dibromoindigo and Related Compounds
Christopher J. Cooksey · Molecules
Open access |
31 Aug 2001 |
230 |
| 26 |
Guidelines for the management of lichen sclerosus
S. Neill, F.M. Tatnall, N.H. Cox · British Journal of Dermatology
|
Oct 2002 |
225 |
| 27 |
The intensive care delirium research agenda: a multinational, interprofessional perspective
Pratik P. Pandharipande et al. · Intensive Care Medicine
Open access |
13 Jun 2017 |
221 |
| 28 |
Linear IgA disease in adults
J.N. LEONARD, G P Haffenden, N. P. Ring et al. · British Journal of Dermatology
|
Sep 1982 |
215 |
| 29 |
Incidence and clinical features of Langerhans cell histiocytosis in the UK and Ireland
Jane A Salotti, Vasanta Rao Nanduri, Mark Stephen Pearce et al. · Archives of Disease in Childhood
|
5 Dec 2008 |
210 |
| 30 |
The surgical risk scale as an improved tool for risk-adjusted analysis in comparative surgical audit
R. Sutton, Simon Bann, Mark Brooks et al. · British journal of surgery
Open access |
Jun 2002 |
202 |
| 31 |
Integrated Control and Management of Neglected Tropical Skin Diseases
Oriol Mitjà et al. · PLoS neglected tropical diseases
Open access |
19 Jan 2017 |
195 |
| 32 |
Is a tourniquet beneficial in total knee replacement surgery?
Toby Oliver Smith, Caroline Blanca Hing · The Knee
|
20 Jul 2009 |
195 |
| 33 |
Impact of gastrostomy tube feeding on the quality of life of carers of children with cerebral palsy
Peter B. Sullivan, Edmund Juszczak, Allison ME Bachlet et al. · Developmental Medicine & Child Neurology
|
Dec 2004 |
188 |
| 34 |
Extent of publication bias in different categories of research cohorts: a meta-analysis of empirical studies
Fujian Song, Sheetal Parekh‐Bhurke, Lee Hooper et al. · BMC Medical Research Methodology
ReviewOpen access |
26 Nov 2009 |
185 |
| 35 |
Gastrostomy tube feeding in children with cerebral palsy: a prospective, longitudinal study
Peter B Sullivan, Edmund Juszczak, Allison ME Bachlet et al. · Developmental Medicine & Child Neurology
|
Feb 2005 |
173 |
| 36 |
Recall for Self and Other in Autism: Children's Memory for Events Experienced by Themselves and Their Peers
Claire Millward, Stuart D. Powell, David J. Messer et al. · Journal of Autism and Developmental Disorders
|
Feb 2000 |
172 |
| 37 |
Why onchocerciasis transmission persists after 15 annual ivermectin mass drug administrations in South-West Cameroon
Armelle Forrer et al. · BMJ Global Health
Open access |
2021 |
166 |
| 38 |
Complete Clinical Response After Preoperative Chemoradiation in Rectal Cancer: Is a “Wait and See” Policy Justified?
Rob Glynne‐Jones, Marina Helen Wallace, J.I. Livingstone et al. · Diseases of the Colon & Rectum
|
27 Nov 2007 |
165 |
| 39 |
Localization of a Gene (MCUL1) for Multiple Cutaneous Leiomyomata and Uterine Fibroids to Chromosome 1q42.3-q43
Neyaz Alam et al. · The American Journal of Human Genetics
Open access |
May 2001 |
161 |
| 40 |
Early versus delayed surgery for anterior cruciate ligament reconstruction: a systematic review and meta‐analysis
Toby Oliver Smith, Leigh Davies, Caroline Blanca Hing · Knee Surgery Sports Traumatology Arthroscopy
Review |
16 Oct 2009 |
152 |
| 41 |
Topical tacrolimus may be effective in the treatment of oral and perineal Crohn's disease
David H. Casson, M. Eltumi, S Tomlin et al. · Gut
Open access |
Sep 2000 |
150 |
| 42 |
Methicillin-resistant Staphylococcus aureus: psychological impact of hospitalization and isolation in an older adult population
Sarah Lilly Farah Tarzi, Paul J Kennedy, S. Stone et al. · Journal of Hospital Infection
|
Dec 2001 |
149 |
| 43 |
Graphene Oxide: Opportunities and Challenges in Biomedicine
Pariya Zare, Mina Aleemardani, Amelia Seifalian et al. · Nanomaterials
Open access |
22 Apr 2021 |
143 |
| 44 |
African Programme for Onchocerciasis Control 1995–2015: Model-Estimated Health Impact and Cost
Luc Edgar Coffeng, Wilma A. Stolk, Honorat Zouré et al. · PLoS neglected tropical diseases
Open access |
31 Jan 2013 |
141 |
| 45 |
Comparison of Surgical Risk Score, POSSUM and p-POSSUM in higher-risk surgical patients
Mark Brooks, R. Sutton, S Sarin · British journal of surgery
|
24 Jun 2005 |
135 |
| 46 |
Can pathological complete response in the primary tumour following pre-operative pelvic chemoradiotherapy for T3–T4 rectal cancer predict for sterilisation of pelvic lymph nodes, a low risk of local recurrence and the appropriateness of local excision?
Rob Hughes, Rob Glynne‐Jones, J. Grainger et al. · International Journal of Colorectal Disease
|
29 Apr 2005 |
131 |
| 47 |
A meta-analysis of randomised controlled trials comparing conventional to minimally invasive approaches for repair of an Achilles tendon rupture
Samuel E. McMahon, Toby Oliver Smith, Caroline Blanca Hing · Foot and Ankle Surgery
Review |
17 Dec 2010 |
127 |
| 48 |
A second update on mapping the human genetic architecture of COVID-19
The COVID-19 Host Genetics Initiative et al. · Nature
Open access3,885 authors |
6 Sep 2023 |
125 |
| 49 |
UK national survey of enucleation, evisceration and orbital implant trends
Prakash Viswanathan, Mandeep S. Sagoo, Jane M. Olver · British Journal of Ophthalmology
Open access |
6 Dec 2006 |
125 |
| 50 |
Population-based cohort study of outcomes following cholecystectomy for benign gallbladder diseases
Ravinder Vohra et al. · British journal of surgery
Open access641 authors |
26 Aug 2016 |
122 |