Institution · Wellcome Sanger Institute
Most cited papers from Wellcome Sanger Institute
What are the most cited papers from Wellcome Sanger Institute?
The most cited paper from Wellcome Sanger Institute is "The Sequence Alignment/Map format and SAMtools" (Heng Li, Bob Handsaker, Alec Wysoker et al., 2009), with 69,061 citations. Next come "Fast and accurate short read alignment with Burrows–Wheeler transform" (63,989) and "Initial sequencing and analysis of the human genome" (24,745).
Showing 50 of 60 papers. Every paper with more than 3,475 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | The Sequence Alignment/Map format and SAMtools Heng Li, Bob Handsaker, Alec Wysoker et al. · Bioinformatics | 8 Jun 2009 | 69,061 |
| 2 | Fast and accurate short read alignment with Burrows–Wheeler transform Heng Li, Richard M. Durbin · Bioinformatics | 18 May 2009 | 63,989 |
| 3 | Initial sequencing and analysis of the human genome Eric S. Lander et al. · Nature | Feb 2001 | 24,745 |
| 4 | A global reference for human genetic variation Corresponding authors et al. · Nature | 29 Sep 2015 | 20,444 |
| 5 | An integrated encyclopedia of DNA elements in the human genome Ian Dunham et al. · Nature | Sep 2012 | 19,751 |
| 6 | The variant call format and VCFtools Petr Danecek, Adam Auton, Gonçalo R. Abecasis et al. · Bioinformatics | 7 Jun 2011 | 18,317 |
| 7 | Twelve years of SAMtools and BCFtools Petr Danecek, James Bonfield, Jennifer Liddle et al. · GigaScience | 29 Jan 2021 | 17,094 |
| 8 | The Pfam Protein Families Database Alex Bateman · Nucleic Acids Research | 2002 | 14,221 |
| 9 | Fast and accurate long-read alignment with Burrows–Wheeler transform Heng Li, Richard M. Durbin · Bioinformatics | 15 Jan 2010 | 13,151 |
| 10 | A human gut microbial gene catalogue established by metagenomic sequencing Junjie Qin et al. · Nature | Mar 2010 | 11,892 |
| 11 | Mutations of the BRAF gene in human cancer Helen Ruth Davies et al. · Nature | Jun 2002 | 10,791 |
| 12 | The mutational constraint spectrum quantified from variation in 141,456 humans Konrad J. Karczewski et al. · Nature | 27 May 2020 | 10,422 |
| 13 | InterProScan 5: genome-scale protein function classification PHILIP M. JONES, David Binns, Hsin-Yu Chang et al. · Bioinformatics | 22 Jan 2014 | 10,355 |
| 14 | Signatures of mutational processes in human cancer Australian Pancreatic Cancer Genome Initiative et al. · Nature | 14 Aug 2013 | 10,284 |
| 15 | EMBOSS: The European Molecular Biology Open Software Suite Peter Rice, Ian Longden, Alan J. Bleasby · Trends in Genetics | Jun 2000 | 10,011 |
| 16 | Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls Paul R. Burton et al. · Nature | 6 Jun 2007 | 9,692 |
| 17 | An integrated map of genetic variation from 1,092 human genomes Gil A. McVean et al. · Nature | 31 Oct 2012 | 8,281 |
| 18 | A map of human genome variation from population-scale sequencing Richard M. Durbin et al. · Nature | 26 Oct 2010 | 8,156 |
| 19 | Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing Marco Gerlinger et al. · New England Journal of Medicine | 7 Mar 2012 | 7,931 |
| 20 | Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence Stewart Thomas Cole et al. · Nature | Jun 1998 | 7,928 |
| 21 | Initial sequencing and comparative analysis of the mouse genome Asif T. Chinwalla et al. · Nature | Dec 2002 | 7,343 |
| 22 | Pfam: the protein families database ROBERT FINN, Alex Bateman, Jody Clements et al. · Nucleic Acids Research | 27 Nov 2013 | 6,604 |
| 23 | The Pfam protein families database: towards a more sustainable future ROBERT FINN, Penelope C. Coggill, Ruth Y. Eberhardt et al. · Nucleic Acids Research | 15 Dec 2015 | 6,569 |
| 24 | Roary: rapid large-scale prokaryote pan genome analysis Andrew J. Page, Carla A. Cummins, Martin B. Hunt et al. · Bioinformatics | 20 Jul 2015 | 6,188 |
| 25 | The International HapMap Project Richard A. Gibbs et al. · Nature | 18 Dec 2003 | 6,187 |
| 26 | The Genome Sequence of Drosophila melanogaster Mark D. Adams et al. · Science | 24 Mar 2000 | 6,049 |
| 27 | Cerebral organoids model human brain development and microcephaly Madeline A. Lancaster, Magdalena Renner, Carol-Anne Martin et al. · Nature | 27 Aug 2013 | 5,545 |
| 28 | Landscape of transcription in human cells Sarah Djebali et al. · Nature | Sep 2012 | 5,447 |
| 29 | COSMIC: the Catalogue Of Somatic Mutations In Cancer John G. Tate et al. · Nucleic Acids Research | 11 Oct 2018 | 5,379 |
| 30 | Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Ewan Birney et al. · Nature | Jun 2007 | 5,310 |
| 31 | The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression Thomas Derrien et al. · Genome Research | Sep 2012 | 5,308 |
| 32 | The zebrafish reference genome sequence and its relationship to the human genome Kerstin Howe et al. · Nature | 16 Apr 2013 | 5,261 |
| 33 | GENCODE: The reference human genome annotation for The ENCODE Project Jennifer Harrow et al. · Genome Research | Sep 2012 | 5,112 |
| 34 | Genetic studies of body mass index yield new insights for obesity biology The LifeLines Cohort Study et al. · Nature | 10 Feb 2015 | 4,954 |
| 35 | Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease Luke Jostins et al. · Nature | 31 Oct 2012 | 4,928 |
| 36 | miRBase: microRNA sequences, targets and gene nomenclature Sam Griffiths‐Jones · Nucleic Acids Research | 28 Dec 2005 | 4,881 |
| 37 | Drug repurposing: progress, challenges and recommendations Sudeep P. Pushpakom, Francesco Iorio, Patrick A. Eyers et al. · Nature Reviews Drug Discovery | 12 Oct 2018 | 4,863 |
| 38 | Richness of human gut microbiome correlates with metabolic markers Emmanuelle Le Chatelier et al. · Nature | 27 Aug 2013 | 4,843 |
| 39 | The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019 Annalisa Buniello et al. · Nucleic Acids Research | 25 Oct 2018 | 4,675 |
| 40 | A second generation human haplotype map of over 3.1 million SNPs Sarah Shaw Murray et al. · Nature | Oct 2007 | 4,615 |
| 41 | Genomic Classification and Prognosis in Acute Myeloid Leukemia Elli Papaemmanuil et al. · New England Journal of Medicine | 8 Jun 2016 | 4,520 |
| 42 | Genome sequence of the human malaria parasite Plasmodium falciparum Malcolm J. Gardner et al. · Nature | Oct 2002 | 4,520 |
| 43 | miRBase: tools for microRNA genomics Sam Griffiths‐Jones, Harpreet Kaur Saini, Stijn van Dongen et al. · Nucleic Acids Research | 8 Nov 2007 | 4,458 |
| 44 | Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells Wanjuan Yang, Jorge Soares, Patricia Greninger et al. · Nucleic Acids Research | 22 Nov 2012 | 4,422 |
| 45 | Global variation in copy number in the human genome Richard Redon et al. · Nature | Nov 2006 | 4,397 |
| 46 | Life with 6000 Genes A. Goffeau, B. G. Barrell, Howard Bussey et al. · Science | 25 Oct 1996 | 4,332 |
| 47 | SARS-CoV-2 variants, spike mutations and immune escape William T. Harvey, Alessandro M. Carabelli, Ben Jackson et al. · Nature Reviews Microbiology | Jun 2021 | 3,930 |
| 48 | Human MicroRNA Targets Bino John, Anton James Enright, Alexei A. Aravin et al. · PLoS Biology | 30 Sep 2004 | 3,928 |
| 49 | The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature | 5 Feb 2020 | 3,854 |
| 50 | The Pfam protein families database Marco Punta, Penny C. Coggill, Ruth Y. Eberhardt et al. · Nucleic Acids Research | 29 Nov 2011 | 3,835 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.